Receptor de endotelina
Los receptores de endotelina son GPCR que median los efectos de las endotelinas, péptidos vasoconstrictores potentes que desempeñan un papel significativo en la regulación del tono vascular, el control de la presión arterial y la proliferación celular. Los antagonistas de los receptores de endotelina se utilizan en el tratamiento de afecciones como la hipertensión arterial pulmonar y la insuficiencia cardíaca. Estos receptores también son objetivos importantes en la investigación sobre enfermedades cardiovasculares y cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de endotelina de alta calidad para apoyar su investigación en biología cardiovascular, oncología y fisiología vascular.
Se han encontrado 85 productos para "Receptor de endotelina".
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CH 141
CAS:CH 141 is a new type of peripheral vasodilator.Fórmula:C19H21N3OForma y color:SolidPeso molecular:307.39ZD-1611
CAS:ZD-1611 is an effective and selective ETA receptor antagonist. It is used for the research of ischemic stroke.Fórmula:C22H24N4O5SPureza:98%Forma y color:SolidPeso molecular:456.51Atrasentan hydrochloride
CAS:Atrasentan hydrochloride (ABT-627 hydrochloride) is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).Fórmula:C29H39ClN2O6Pureza:99.75%Forma y color:SolidPeso molecular:547.08Aminaftone
CAS:Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.Fórmula:C18H15NO4Pureza:96.31% - 97.57%Forma y color:SolidPeso molecular:309.32Avosentan
CAS:Avosentan（Ro 67-0565; SPP-301） is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.Fórmula:C23H21N5O5SPureza:98.31% - 99.86%Forma y color:SolidPeso molecular:479.51BMS-193884
CAS:BMS-193884 is an oral endothelin antagonist for the treatment of congestive heart failure (CHF) and pulmonary arterial hypertension.Fórmula:C20H17N3O4SForma y color:SolidPeso molecular:395.43CI 1020
CAS:endothelin-A receptor (ETA) antagonistFórmula:C28H26O9Pureza:98%Forma y color:SolidPeso molecular:506.5PD-156707
CAS:PD-156707 is a selective antagonist of endothelin A receptor.Fórmula:C28H26NaO9Pureza:98%Forma y color:SolidPeso molecular:529.497ABT-546
CAS:ABT-546 is a potent, selective endothelin ETA receptor antagonist, Ki 0.46 nM for [125I]ET-1 binding.Fórmula:C30H48N2O6Pureza:98%Forma y color:SolidPeso molecular:532.71TBC3711
CAS:TBC3711 is an endothelin receptor modulator. It is used for the research of endothelin-mediated disorders.Fórmula:C20H21N3O5S2Pureza:98%Forma y color:SolidPeso molecular:447.53Sitaxsentan
CAS:Sitaxsentan (TBC-11251), a selective ETA receptor antagonist, prevents vasoconstriction by blocking endothelin.Fórmula:C18H15ClN2O6S2Pureza:97.99% - 98.71%Forma y color:SolidPeso molecular:454.9SB-209670
CAS:SB-209670 is a selective endothelin receptor antagonist that inhibits the activity of ET(B) receptors in rat vascular endothelium and vascular smooth muscle.Fórmula:C29H28O9Pureza:98.29% - 99.40%Forma y color:SolidPeso molecular:520.53Ref: TM-T34541
1mg315,00€5mg745,00€1mL*10mM (DMSO)755,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€Edonentan
CAS:Edonentan is A potent endothelin A (ETA) receptor antagonist that can be used to study heart failure.Fórmula:C28H32N4O5SPureza:98.07% - 99.13%Forma y color:White SolidPeso molecular:536.64BMS 182874
CAS:BMS 182874: Oral ETA antagonist, IC50=0.150 μM, Ki=0.055 μM, lowers hypertension in rats.Fórmula:C17H19N3O3SPureza:99.73%Forma y color:Yellow SolidPeso molecular:345.42L-749329
CAS:L-749329 is a ligand of ET(A) and ET(B) endothelin receptor.Fórmula:C28H29NO8SPureza:98%Forma y color:SolidPeso molecular:539.6Clazosentan
CAS:Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.Fórmula:C25H23N9O6SPureza:97.26% - >99.99%Forma y color:SolidPeso molecular:577.57Ref: TM-T64084
1mg71,00€5mg167,00€1mL*10mM (DMSO)205,00€10mg258,00€25mg565,00€50mg888,00€100mg1.161,00€IRL 2500
CAS:IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.Fórmula:C36H35N3O4Pureza:99.36%Forma y color:SolidPeso molecular:573.68Diosuxentan
CAS:Diosuxentan is an inhibitor of ETA and is utilized in research pertaining to cardiovascular, renal, and neuronal inflammatory diseases.Fórmula:C20H21BrN6O7SForma y color:SolidPeso molecular:569.39K-8794
CAS:K-8794 is an orally active and selective endothelin receptor ETB antagonist that can be utilized in cardiovascular disease research.Fórmula:C36H38N6O6SForma y color:SolidPeso molecular:682.789BMS-248360
CAS:BMS-248360: Oral dual hAT1/hETA antagonist with Kis of 10nM & 1.9nM, respectively; treats hypertension.Fórmula:C36H45N5O5SPureza:98%Forma y color:SolidPeso molecular:659.84
