Receptor de bombesina
Los receptores de bombesina son un grupo de GPCR que se activan por péptidos similares a la bombesina, los cuales están involucrados en la regulación de la función gastrointestinal, el equilibrio energético y la proliferación celular. Estos receptores son de particular interés en la investigación del cáncer, ya que a menudo están sobreexpresados en ciertos tipos de tumores. Los antagonistas de los receptores de bombesina se estudian por su potencial como terapias contra el cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de bombesina de alta calidad para apoyar su investigación en oncología, fisiología gastrointestinal y señalización de receptores.
Se han encontrado 30 productos de "Receptor de bombesina"
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CD80-IN-3
CAS:<p>CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM).</p>Fórmula:C17H10FN3O3Pureza:98.08%Forma y color:SolidPeso molecular:323.28AMTG-DA1
<p>AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.</p>Fórmula:C101H149IN22O25Forma y color:SolidPeso molecular:2197.0109RC-3095
CAS:<p>RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.</p>Fórmula:C56H79N15O9Pureza:98%Forma y color:SolidPeso molecular:1106.32BA 1
CAS:<p>Potent BB1, BB2, and BB3 agonist; IC50: 0.26, 1.55, 2.52 nM. Boosts glucose transport in myocytes, promotes cancer cell growth in vitro.</p>Fórmula:C57H76N14O11Pureza:98%Forma y color:SolidPeso molecular:1133.32PSMA/GRPR ligand 1
<p>PSMA/GRPR ligand 1 (compound 3) is a bispecific ligand with dual targeting capabilities for tumors that express PSMA(+) and GRPR(+).</p>Forma y color:Odour Solid[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
CAS:<p>Broad-spectrum inverse agonist; potent at ghrelin receptor (EC50=5.2 nM); blocks other neuropeptide receptors; induces apoptosis; inhibits tumor growth.</p>Fórmula:C79H109N19O12Pureza:98%Forma y color:SolidPeso molecular:1516.85[D-Phe12]-Bombesin
CAS:<p>Bombesin receptor antagonist</p>Fórmula:C74H112N22O18SPureza:98%Forma y color:SolidPeso molecular:1629.88[D-Phe12,Leu14]-Bombesin
CAS:<p>Bombesin receptor blocker; stops binding in rat brain (IC50=2 μM), hinders amylase release (IC50=4 μM), reduces appetite suppression in vivo.</p>Fórmula:C77H113F3N22O20Pureza:98%Forma y color:SolidPeso molecular:1724.9(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
CAS:<p>(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].</p>Fórmula:C49H69N13O9Forma y color:SolidPeso molecular:984.15BA 1 TFA
<p>BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.</p>Fórmula:C59H77F3N14O13Forma y color:SolidPeso molecular:1247.32Ici 216140
CAS:<p>ICI 216140: GRP/bombesin receptor 2 blocker, potent at 2 nM. Reduces amylase at 2 mg/kg and lowers bombesin-induced blood pressure at 1 mM in rats.</p>Fórmula:C45H65N13O8Forma y color:SolidPeso molecular:916.08GRP (14-27) (human, porcine, canine)
CAS:<p>GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does not</p>Fórmula:C75H110N24O16S2Pureza:98%Forma y color:SolidPeso molecular:1667.96GB-6
CAS:<p>GB-6, a short linear peptide that selectively binds to the gastrin releasing peptide receptor (GRPR), shows potential as a high-contrast imaging probe due to</p>Fórmula:C32H45N11O8Pureza:98%Forma y color:SolidPeso molecular:711.77RC-3095 TFA
CAS:<p>RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.</p>Fórmula:C58H80F3N15O11Pureza:98%Forma y color:SolidPeso molecular:1220.34Bombesin
CAS:<p>Bombesin: 14-amino acid peptide from toad skin with two mammalian homologs, neuromedin B and gastrin-releasing peptide.</p>Fórmula:C71H110N24O18SForma y color:While Lyophilized PowderPeso molecular:1619.85PD176252
CAS:<p>PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.</p>Fórmula:C32H36N6O5Pureza:99.18%Forma y color:SolidPeso molecular:584.67ML-18
CAS:<p>ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.</p>Fórmula:C32H35N5O5Pureza:98.62% - >99.99%Forma y color:SolidPeso molecular:569.65kuwanon G
CAS:<p>Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.</p>Fórmula:C40H36O11Pureza:98% - 99.57%Forma y color:SolidPeso molecular:692.71Litorin acetate(55749-97-8 Free base)
<p>Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.</p>Fórmula:C53H72N14O13SPureza:98.61%Forma y color:SolidPeso molecular:1145.29Bombesin acetate(31362-50-2 free base)
CAS:<p>Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina).</p>Fórmula:C73H114N24O20SPureza:98.44%Forma y color:SolidPeso molecular:1679.92
![[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1931.webp&w=3840&q=75)
![[D-Phe12]-Bombesin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP2239.webp&w=3840&q=75)
![[D-Phe12,Leu14]-Bombesin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1916.webp&w=3840&q=75)
