PKA

Ellagic acid is a fused four ring compound isolated from the kino of Eucalyptus maculata …

MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).

Bucladesine, PKA activator, is a cyclic nucleotide derivative that mimics the action of endogenous cAMP …

Theophylline-7-acetic acid, a stimulant drug of the xanthine chemical class, acts as an adenosine receptor …

Piceatannol is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine …

A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride …

Warangalone is an anti-malarial compound that can inhibit the growth of both strains of parasite …

Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.

KT5720 is a cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase A (PKA) (Ki: 60 …

HA-1004 is a inhibitor of PKG, PKA, PKC and MLC.

Cycloheterophyllin has an antioxidant effect, it is a photoprotective agent that inhibits ultraviolet A (UVA)-induced …

A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for …

Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer …

A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and …

Exisulind induces apoptosis through the activation of protein kinase G (PKG). Exisulind exhibits antineoplastic activity …

Isopedicin has anti-inflammatory functions, it inhibits the O(2)(*)(-) production in human neutrophils by an elevation …

Isocupressic acid induces abortion in pregnant cows when ingested primarily during the last trimester, it …

H-1152 dihydrochloride is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of …

WAY-312157 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.

Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, …

Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK).

alpha-Amyrin palmitate is antiarthritic in the adjuvant model of arthritis in rats. alpha-Amyrin palmitate is …

Capivasertib (AZD5363) is a new-type orally available inhibitor of the serine/threonine protein kinase AKT (IC50s: …

8-Bromo-cAMP is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent …

H 89 is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: …

PKI (5-24) Acetate is a high affinity PKA inhibitor (Ki = 2.3 nM).

PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and …

PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG).PKG Substrate is a …

Ipatasertib dihydrochloride is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and …

RO-3306 is a selectivity ATP-competitive CDK1 inhibitor (Ki: 20 nM). The selectivity of RO-3306 for …

CCT128930 hydrochloride is a potent and selective inhibitor of AKT with IC50 of 6 nM. …

MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 …

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE, also known as cGMP, is a cellular regulatory agent and has been …

PKA Inhibitor Fragment (6-22) amide Acetate is a PKA inhibitor with a Ki of 2.8 …

CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 …

R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. …

Rottlerin is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor …

CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, …

Staurosporine is a potent PKC inhibitor for PKCα/γ/η (IC50: 2/5/4 nM), less potent to PKCε …

HA-100 is an inhibitor of protein kinase

A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within …

AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 …

GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over …

Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: …

Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA …

Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.

Metadoxine is a neurotransmitter stimulant.

Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of …

ML-7 Hcl is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain …

CREBtide acetate is a synthetic substrate for PKA (Km=3.9 μM), which is based on the …

A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and …

BX-912 is a specific inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1, IC50: 12 nM). The selectivity of …

Hydroxyfasudil is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).

PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by …

2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.

AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.

NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over …

PKG inhibitor peptide TFA is an inhibitor of atp-competitive cGMP-dependent protein kinase (PKG), Ki 86 …

8-Bromo-cGMP sodium, a membrane-permeable analogue of cGMP, is a PKG (protein kinase G) activator. 8-Bromo-cGMP …

LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM …

HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein