AMPK
Los inhibidores de AMPK son compuestos que inhiben la Proteína Quinasa Activada por AMP (AMPK), una enzima clave en la homeostasis energética celular. La AMPK se activa en respuesta a bajos niveles de energía en las células y regula procesos como la captación de glucosa, la oxidación de ácidos grasos y la biogénesis mitocondrial. Inhibir la AMPK es fundamental para estudiar su papel en enfermedades metabólicas, cáncer y envejecimiento. En CymitQuimica, ofrecemos una variedad de inhibidores de AMPK para apoyar su investigación en metabolismo, oncología y enfermedades relacionadas con la edad.
Se han encontrado 165 productos para "AMPK".
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Glycometabolism Compound Library
xnum glycometabolism-related comounds, can be used for HTS and HCT;Forma y color:Odour SolidAMPK-Targeted Compound Library
xnum well-chosen unique AMPK-targeted small molecules；Forma y color:Odour SolidWu-5
CAS:Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis.Fórmula:C15H13NO7SPureza:99.65%Forma y color:SolidPeso molecular:351.33Resolvin D3
CAS:Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation.Fórmula:C22H32O5Forma y color:SolidPeso molecular:376.493Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB.Forma y color:Transparent LiquidMetformin-D6 hydrochloride
CAS:Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Fórmula:C4H12ClN5Pureza:98.1%Forma y color:SolidPeso molecular:171.66Teneligliptin hydrobromide hydrate
CAS:Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.Fórmula:C44H67Br5N12O3S2Forma y color:SolidPeso molecular:1275.731Biguanide
CAS:Biguanide can reduce oxidative stress in rats with hyperglycemia.Fórmula:C2H7N5Forma y color:SolidPeso molecular:101.11BC1618
CAS:BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Fórmula:C24H24F3NO2Pureza:99.95%Forma y color:SolidPeso molecular:415.4481Metformin
CAS:Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Fórmula:C4H11N5Pureza:99.77% - >99.99%Forma y color:SolidPeso molecular:129.1636O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Fórmula:C16H11Cl2N3O2SPureza:99.84% - ≥98%Forma y color:White SolidPeso molecular:380.248EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Fórmula:C30H36Br2N4O2Pureza:99.48%Forma y color:SolidPeso molecular:644.44GSK621
CAS:GSK621 is a specific and potent AMPK activator.Fórmula:C26H20ClN3O5Pureza:97.02% - 97.05%Forma y color:SolidPeso molecular:489.907STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Fórmula:C25H23N3O4SPureza:99.96%Forma y color:SolidPeso molecular:461.533Platycodin D
CAS:Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA.Fórmula:C57H92O28Pureza:99.2% - 99.65%Forma y color:White SolidPeso molecular:1225.3236Bempedoic acid
CAS:Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Fórmula:C19H36O5Pureza:99.85% - 99.94%Forma y color:White SolidPeso molecular:344.4861Kahweol
CAS:Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFórmula:C20H26O3Pureza:99.26% - 99.86%Forma y color:SolidPeso molecular:314.42AMPK activator 2
CAS:AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Fórmula:C13H18F3N5Pureza:99.86%Forma y color:SolidPeso molecular:301.31Dorsomorphin dihydrochloride
CAS:Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFórmula:C24H25N5O·2HClPureza:97.74% - 99.89%Forma y color:SolidPeso molecular:472.41COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Fórmula:C13H8Cl4N2OPureza:98.96%Forma y color:SolidPeso molecular:350.027
