AMPK
Los inhibidores de AMPK son compuestos que inhiben la Proteína Quinasa Activada por AMP (AMPK), una enzima clave en la homeostasis energética celular. La AMPK se activa en respuesta a bajos niveles de energía en las células y regula procesos como la captación de glucosa, la oxidación de ácidos grasos y la biogénesis mitocondrial. Inhibir la AMPK es fundamental para estudiar su papel en enfermedades metabólicas, cáncer y envejecimiento. En CymitQuimica, ofrecemos una variedad de inhibidores de AMPK para apoyar su investigación en metabolismo, oncología y enfermedades relacionadas con la edad.
Se han encontrado 165 productos para "AMPK".
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Dorsomorphin dihydrochloride
CAS:Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFórmula:C24H25N5O·2HClPureza:97.74% - 99.89%Forma y color:SolidPeso molecular:472.41COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Fórmula:C13H8Cl4N2OPureza:98.96%Forma y color:SolidPeso molecular:350.027Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Fórmula:C24H25N5OPureza:98% - 99.92%Forma y color:SolidPeso molecular:399.4882ON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Fórmula:C24H27N7OPureza:99.53% - 99.7%Forma y color:SolidPeso molecular:429.5175IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Fórmula:C21H21NO4Pureza:98.14% - 98.47%Forma y color:SolidPeso molecular:351.3957AMAROGENTIN
CAS:Amarogentin, extracted from Swertia/Gentiana roots, aids liver cancer prevention/treatment by affecting cell cycle and apoptosis.Fórmula:C29H30O13Pureza:99.98% - ≥95%Forma y color:SolidPeso molecular:586.5407WH-4-025
CAS:WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Fórmula:C39H38F3N7O5Pureza:99.41%Forma y color:White SolidPeso molecular:741.7581STO-609
CAS:STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.Fórmula:C19H10N2O3Pureza:97.14% - 99.35%Forma y color:SolidPeso molecular:314.29MK-3903
CAS:MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Fórmula:C27H19ClN2O3Pureza:98.63% - 99.75%Forma y color:SolidPeso molecular:454.904Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFórmula:C19H17NO4Pureza:98.08% - 99.18%Forma y color:SolidPeso molecular:323.3426[6]-Gingerol
CAS:[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Fórmula:C17H26O4Pureza:98% - 99.95%Forma y color:White SolidPeso molecular:294.3859ARN-3236
CAS:ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFórmula:C19H16N2O2SPureza:98.89% - 99.7%Forma y color:SolidPeso molecular:336.408Ginkgolide C
CAS:Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Fórmula:C20H24O11Pureza:99.71% - 99.98%Forma y color:White PowderPeso molecular:440.398Vaccarin
CAS:Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Fórmula:C32H38O19Pureza:99.16% - 99.97%Forma y color:SolidPeso molecular:726.6327Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFórmula:C21H24O10Pureza:97.16%Forma y color:SolidPeso molecular:436.4093MRT67307 HCl
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Fórmula:C26H37ClN6O2Pureza:98.19%Forma y color:SolidPeso molecular:501.07Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Fórmula:C16H30O2Pureza:99.76%Forma y color:SolidPeso molecular:254.4082Buformin
CAS:Buformin, a biguanide oral antidiabetic, inhibits liver glucose production and improves insulin sensitivity.Fórmula:C6H15N5Forma y color:SolidPeso molecular:157.22DASA-58
CAS:DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.Fórmula:C19H23N3O6S2Pureza:96.96% - 99.28%Forma y color:SolidPeso molecular:453.532MOTS-c, human Acetate
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Fórmula:C103H156N28O24S2Pureza:99.93%Forma y color:White SolidPeso molecular:2234.64
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