AMPK
Los inhibidores de AMPK son compuestos que inhiben la Proteína Quinasa Activada por AMP (AMPK), una enzima clave en la homeostasis energética celular. La AMPK se activa en respuesta a bajos niveles de energía en las células y regula procesos como la captación de glucosa, la oxidación de ácidos grasos y la biogénesis mitocondrial. Inhibir la AMPK es fundamental para estudiar su papel en enfermedades metabólicas, cáncer y envejecimiento. En CymitQuimica, ofrecemos una variedad de inhibidores de AMPK para apoyar su investigación en metabolismo, oncología y enfermedades relacionadas con la edad.
Se han encontrado 162 productos para "AMPK".
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ULK1-IN-2
CAS:ULK1-IN-2, a potent anticancer agent, inhibits ULK1, induces apoptosis, blocks autophagy, and shows high cytotoxicity with an IC50 of 1.94 μM in A549 cells.Fórmula:C19H16BrFN4O6Pureza:99.07% - 99.97%Forma y color:SolidPeso molecular:495.26AMPK activator 6
CAS:AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.Fórmula:C25H28O5Forma y color:SolidPeso molecular:408.49HL271
CAS:HL271 hydrochloride is a chemical derivative of metformin and a potent AMPK activator that enhances AMPK phosphorylation levels.Fórmula:C13H17ClF3N5OPureza:99.84%Forma y color:SolidPeso molecular:351.76D561-0775
CAS:D561-0775 AMPK agonist antitumor compound for metabolic regulation, glycolysis suppression, cancer resistance pathways.Fórmula:C21H15BrN4O3Pureza:98.67%Forma y color:SolidPeso molecular:451.27GL-V9
CAS:GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.Fórmula:C24H27NO5Forma y color:SolidPeso molecular:409.47SMTIN-T140
CAS:SMTIN-T140: strong TRAP1 inhibitor, IC50=1.646μM, anticancer; disrupts mitochondria, boosts ROS, activates AMPK, shrinks PC3 tumors, no in vivo toxicity.Fórmula:C36H34BrClFN5OPPureza:98%Forma y color:SolidPeso molecular:718.02IND 1316
CAS:IND 1316 is an activator of AMP-activated protein kinase (AMPK).Fórmula:C22H17NO3Forma y color:SolidPeso molecular:343.38OSU-53
CAS:OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.Fórmula:C25H24F3N3O6S2Forma y color:SolidPeso molecular:583.6AMPK activator 1
CAS:AMPK activator 1 is an AMPK activator(compound No.1-75, EC50: <0.1μM).Fórmula:C32H33F3N4O3Pureza:98%Forma y color:SolidPeso molecular:578.62AMPK activator 12
CAS:AMPK activator 12 is an AMPK activator and GDF15 inducer that elevates the expression level of GDF15 protein for cancer research.Fórmula:C23H24BrNO2Pureza:99.57%Forma y color:SolidPeso molecular:426.35LRRK2/NUAK1/TYK2-IN-1
CAS:LRRK2/NUAK1/TYK2-IN-1 inhibits LRRK2, TYK2, NUAK1 with IC50 < 10 nM, useful in autoimmune research.Fórmula:C20H11F3N6Forma y color:SolidPeso molecular:392.34AMPK activator 8
CAS:AMPK activator 8 targets rAMPK α1β1γ1/α2β1γ1/α1β2γ1 (EC50: 11/27/4 nM) for type 2 diabetes research.Fórmula:C25H21ClN2O6Forma y color:SolidPeso molecular:480.9AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Fórmula:C25H20N4O2Pureza:98%Forma y color:SolidPeso molecular:408.45AMDE-1
CAS:AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.Fórmula:C18H8ClF6N3Pureza:90%Forma y color:SolidPeso molecular:415.72XMD-17-51
CAS:XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Fórmula:C21H24N8OPureza:99.04%Forma y color:SolidPeso molecular:404.47YM-53601 free base
CAS:YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Fórmula:C21H21FN2OPureza:98%Forma y color:SolidPeso molecular:336.4AMPK activator 9
CAS:AMPK activator 9 (ZM-6) is a potent α2β1γ1 agonist with an EC50 of 1.1 µM, potential for type 2 diabetes research.Fórmula:C31H28F4N4O4Forma y color:SolidPeso molecular:596.57PF-249
CAS:PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.Fórmula:C17H16ClN3O3Pureza:97.01%Forma y color:SolidPeso molecular:345.78Ref: TM-T24626
1mg46,00€5mg92,00€1mL*10mM (DMSO)100,00€10mg147,00€25mg236,00€50mg344,00€100mg482,00€200mg662,00€AMPK-IN-3
CAS:AMPK-IN-3: potent, selective AMPK (α2/α1) & KDR inhibitor; IC50: 60.7/107/3820 nM; anticancer in K562 cells.Fórmula:C25H33N5O3Pureza:97.25%Forma y color:SolidPeso molecular:451.56
