Compuestos policíclicos

<p>Applications 4,4'-Di-tert-butyl-2,2'-bipyridine acts as a reagent in the preparation, antiproliferative and cytotoxic activity of apoptotic ruthenium nitrogen heterocyclic complexes via combinatorial library synthesis.<br>References Mulcahy, S. P., et al.: Dalton Trans., 39, 177 (2010)<br></p>

<p>Applications 1,1’-Bicyclohexyl is a hydrocarbon component present in diesel fuel.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Patino, P. et al.: Energy. Fuel., 16, 1470 (2002); Shokri, S. et al.: Chem. Tech., An Ind. J., 1, 119 (2006);<br></p>

<p>Applications 3-Hydroxyindole is a mutation product of toluene-4-monooxygenase (T4MO), that gets spontaneously converted to indigo. Used in the preparation of indolyl-oxadiazoles with anticonvulsant activity.<br>References Rajak, H. et al.: Int. J. Pharm. Sci. Nanotech., 2, 661 (2009); McClay, K. et al.: Appl. Environ. Microbiol., 71, 5476 (2005); Berry, A. et al.: J. Ind. Microbiol. Biotech., 28, 127 (2002)<br></p>

<p>Applications tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate (cas# 203661-69-2) is a useful research chemical.<br></p>

<p>Applications 6-Dimethylaminopurine-9-riboside (cas# 2620-62-4) is a compound useful in organic synthesis.<br>References Elion, G.B., et al.: JACS, 74, 411-414 (1952), Kelley, J.L., et al.: J. Med. Chem., 32, 1020-1024 (1989)<br></p>

<p>Applications 3-Bicyclo[3.2.1]octanone is used as a reactant in the synthesis of polycyclic acid derivatives as selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).<br>References Ye, X., et. al.: Bioorg. Med. Chem. Lett., 21, 6699 (2011)<br></p>

<p>Applications 2-Butoxyquinoline-4-carboxylic Acid is used in the organic synthesis of o-(β-diethylaminoethyl)cinchoninaldoxime with local anesthetic activity<br>References Rossi, S., et al.: Farmaco, Edizione Scientifica, 34, 486 (1979)<br></p>

<p>Applications Indole-3-acetonitrile is an indole derivative involved in the biosynthesis of the plant hormone indole acetic acid (I577340) via the indole-3-acetaldoxime pathway.<br>References Kong, W., et al.: Plant Cell Physiol, 56, 715-726 (2015)<br></p>

<p>Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation.<br>References Khanna P., et al.: Biochemistry, 40, 1441 (2001);<br></p>

<p>Applications 1,2,3,4-tetrahydro-1,2-dimethyl-4,8-isoquinolinediol, is a Tetrahydroisoquinoline derivative, that can be used for the synthesis of pharmaceutical drugs, containing tetrahydroisoquinoline skeleton.<br></p>

<p>Applications Isoquinoline is used in the synthesis of nitrated indenoisoquinolines as a potent topoisomerase I inhibitor.This compound is a contaminant of emerging concern (CECs).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Morrell, A., et. al.: J. Med. Chem., 49, 7740 (2006)<br></p>

<p>Applications 1-Ethyl-2,3,3-trimethylindolenium-5-sulfonate (cas# 146368-07-2) is a compound useful in organic synthesis.<br></p>

<p>Applications A naturally occurring purine derivative. Pharmaceuticals, Intermediates &amp; Fine Chemicals<br>References Jansen, R., et al.: Clin. Biochem., 38, 362 (2005), Vorst, O., et al.: Metabolomics, 1, 169 (2005), Want, E., et al.: ChemBioChem., 6, 1941 (2005), van der Werf, M., et al.: Anal. Biochem., 370, 17 (2007),<br></p>

<p>Applications 2,2':6',2''-Terpyridine (cas# 1148-79-4) is a useful research chemical.<br></p>

<p>Applications 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction.<br>References Hiyama, T., et al.: Bull. Chem. Soc. Japan, 68, 364 (1995); Fabris, J., et al.: Synth., 44, 1700 (2012)<br></p>

<p>Applications 8-Hydroxyquinoline (cas# 148-24-3) is a compound useful in organic synthesis.<br></p>

<p>Applications This compound has estrogenic activity. It exhibits bright blue fluorescence in neutral or acid solution, and greenish-yellow fluorescence in strong alkali solution.<br>References Wolfbeis, O.S. &amp; K. Schaffner: Photochem. Photobiol., 32, 143(1980), Bickoff et al.: J.Am. Chem Soc. 80, 3969 (1958)<br></p>

<p>Covid-19 is a polymer that can be used as a coating for surfaces, such as plastics and metals. Covid-19 has been shown to have antibacterial properties against bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. Covid-19 also has functional groups that can be used in analytical methods to determine the concentration of drugs in biological samples. Covid-19 is soluble in polyvinyl alcohol and glycerol, which are both common additives in pharmaceuticals. Covid-19 has optical properties that make it suitable for use as a coating on contact lenses or other ophthalmic devices.</p>

<p>Angelicin is a furanocoumarin compound, which is derived from various plant sources, particularly within the Apiaceae family. The source of angelicin is often linked to traditional medicinal plants, where it is extracted and subsequently isolated for scientific investigation. Angelicin's mode of action involves intercalating within DNA strands, thereby affecting transcription and replication processes. This action is understood to be primarily photoactivated, leading to the formation of covalent bonds with DNA upon exposure to ultraviolet light, which can result in cross-linking.</p>

<p>4,4',6,6'-Tetramethyl-2,2'-bipyridine (TMTB) is a small molecule that can be used as an efficient and cost-effective catalyst for the production of hydrogen from water. TMTB is able to transform solar energy into chemical energy by converting light absorbed in a semiconductor material to an electric current. TMTB has been shown to improve the efficiency of solar cells by boosting the performance of the catalysts that drive chemical reactions in the devices. This effect was found to be synergistic with other materials such as graphene oxide and tungsten disulfide. In addition, TMTB nanoparticles were shown to have a normalizing effect on the charge density in photoelectrochemical cells, which may lead to improved stability and durability.</p>

<p>Please enquire for more information about 3-(4-ethoxyphenyl)spiro[1,3-thiazolidine-2,3'-indoline]-4,7-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Thioxanthine is a hydrated form of xanthine, which is a purine base that occurs in all living cells. This compound has been shown to be able to inhibit the growth of resistant mutants and the formation of atherosclerotic lesions in mice. 2-Thioxanthine also inhibits the transfer reactions that are required for bacterial DNA synthesis. The stability of 2-thioxanthine can be increased by forming stable complexes with hydrochloric acid and by reducing the pH to less than 7. 2-Thioxanthine has been shown to have genotoxic effects on mouse liver cells and human fibroblasts, as well as pharmacological properties against cardiovascular disease.</p>

<p>Quinolin-4-ylboronic acid is a heterocyclic compound with two nitrogen atoms that are attached to the ring by means of carbonyl groups. This compound is a precursor in the synthesis of the drug dorsomorphin, which is used for pain relief. It also has an important role in pharmacokinetics because it can be used as a marker for estimating blood levels of other drugs. Quinolin-4-ylboronic acid yields an active form, quinolin-4-yl boronic acid, when reacted with piperazine in basic conditions. The drug ldn-193189 is a derivative of this active form and has been evaluated as a potential drug for treating osteoporosis and cancer.</p>

<p>7-Ethoxycoumarin is a fluorescent substrate used in biochemical research, which is derived synthetically. It undergoes biotransformation primarily via oxidative dealkylation, catalyzed by cytochrome P450 enzymes, resulting in the formation of 7-hydroxycoumarin. By monitoring the fluorescent 7-hydroxycoumarin, researchers can assess enzymatic activity and study metabolic pathways.</p>

<p>4-[(7-Chloro-4-quinolinyl)amino]-1-pentanol (QLT) is a drug that has been shown to be effective against both healthy volunteers and malaria patients. It is a prodrug that is metabolized by the liver into 7-chloroquinalone, which inhibits the growth of plasmodium falciparum. QLT has been shown to be safe and well tolerated in studies with healthy volunteers, and it does not appear to cause significant adverse effects. QLT also has an effect on T cells, which may be due to its ability to inhibit protein synthesis and cell division.</p>

<p>8-Aminoquinoline is a fluorescent probe that is used to detect the presence of nitrite ions in biological samples. It is used in electron paramagnetic resonance (EPR) experiments and can be used as a chemical inhibitor of cytochrome P450 enzymes. 8-Aminoquinoline has been shown to have minimal toxicity in animal models. It has been shown to inhibit the growth of Leishmania, an organism that causes leishmaniasis, by arresting protein synthesis at the ribosome level. The drug interactions of 8-aminoquinoline have not been well studied, but it may be necessary for patients to avoid other drugs that are metabolized by cytochrome P450 enzymes when taking this agent.</p>

<p>Indoline-2-carboxylic acid is a photophysical molecule with an absorption maximum at 518 nm. It has been shown to inhibit the activity of enzymes such as cyclooxygenase, lipoxygenase, and monoamine oxidases. This compound has been found to be effective in the treatment of cancer cells. Indoline-2-carboxylic acid is also used in pharmaceutical preparations, where it binds to enantiomers of other molecules and inhibits their biological activity. Indoline-2-carboxylic acid reacts with hydrochloric acid to form allyl carbonate and amide.</p>

<p>4-Hydroxy-2-methylindole is an organic compound that belongs to the class of metal salts. It can be obtained as a white solid by reacting indole with alkali metal hydroxide or alkali metal carbonate in the presence of water at high temperatures. The reaction yields 4-hydroxy-2-methylindole and hydrogen chloride gas, which are removed by distillation. 4-Hydroxy-2-methylindole is used in the production of epichlorohydrin, which is a raw material for polyurethane resins and olefins.</p>

<p>Radiosensitiser in hypoxic tumours</p>

<p>4-Nitrobenzyl (4R,5R,6S)-3-[(diphenylphosphono)oxy]-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylat e is a synthetic compound that is used as an alkalizer and impurity scavenger in the manufacture of pesticides and other organic chemicals. It has been shown to be a stereoselective herbicide with acetonitrile as its primary degradation product. The compound has also been found to be a potent inhibitor of the enzyme carbapenemase, which may lead to increased resistance to antibiotics such as monosodium salt of ertapenem.</p>

<p>Fraxin is a naturally occurring anticoagulant, which is derived from the bark of certain species of the Fraxinus tree. It functions by inhibiting thrombin and other key enzymes in the coagulation cascade, thus preventing the formation of blood clots. This mode of action makes it particularly valuable in research settings focused on cardiovascular diseases, as well as in the development of therapeutic agents targeting coagulopathies.</p>

<p>Quinoline 2,4-dicarboxylic acid (QDA) is a novel cytotoxic agent that targets cervical cancer cells. It inhibits the uptake of glucose and other nutrients by cervical cancer cells, leading to cell death through apoptosis. QDA also inhibits the expression of genes involved in cross-linking reactions, which are important for the structural integrity of proteins. This agent has been shown to inhibit the growth of aniline-induced breast cancer cells and glutamate-stimulated PC12 cells. QDA binds to DNA and forms covalent bonds with nucleotide bases, inhibiting DNA synthesis, as well as interfering with protein synthesis and cell division. The QDA mechanism is similar to that of benzoquinolines and estrone sulfate.</p>

<p>3-Methylphenanthrene is a compound that inhibits the reductase activity of aromatic hydrocarbons. 3-Methylphenanthrene has been shown to inhibit both bacterial and mammalian reductases, with interactive effects on the enzyme's substrate molecule. It also shows an inhibitory effect on axonal growth, which may be due to its ability to reduce fatty acid uptake, as well as its ability to interact with the aromatic hydrocarbon uptake system. 3-Methylphenanthrene is easily detected by spectrometry analyses and can be used as a substrate molecule for bacterial enzymes.</p>

<p>Please enquire for more information about 13,4-diaza-5-(tert-butyl)-2-hydroxy-7-oxotricyclo[6.4.0.0&lt;2,6&gt;]dodeca-1(8),4,9,11-tetraene-3-carboxamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Indole-2-carboxylic acid is a potent inducer of the cytochrome P450 enzyme. It has been shown to bind to the active site of the enzyme and inhibit its activity. Indole-2-carboxylic acid is an acidic molecule with two hydrogen atoms that are capable of forming an intermolecular hydrogen bond, which may be responsible for its ability to bind to the enzyme. This compound has been shown to inhibit the activity of other enzymes such as xanthine oxidase and phosphodiesterase, which are involved in chemical reactions that produce reactive oxygen species (ROS). ROS are implicated in neuronal death and Parkinson's disease.</p>

<p>6-Azaindole is a drug that inhibits the activity of the enzyme aromatase, which is responsible for the conversion of testosterone to estrogen. 6-Azaindole has shown potent inhibitory activity against cancer cells in vitro and in vivo. It also has an inhibitory effect on pain relief mechanisms at low doses, but not at high doses. The mechanism of action is complex and multifactorial; it may involve inhibition of proton transfer, receptor activity, and/or inhibition of nitrogen atoms. The synthesis of 6-azaindoles can be carried out using a variety of methods and starting materials, including asymmetric synthesis or reduction of an n-oxide moiety.</p>

<p>4-Imidazoleacetic acid HCl is a fluorescent probe that binds to the α1 subunit of the dinucleotide phosphate (NADH) oxidoreductase. It has been shown to inhibit mitochondrial functions, which may be due to its ability to inhibit the pentose phosphate pathway and reduce reactive oxygen species levels. 4-Imidazoleacetic acid HCl has also shown inhibitory properties against congestive heart failure by acting on the mitochondria and inhibiting energy metabolism. It can also be used as a chemical biology tool for studying protein interactions with NADH dehydrogenase. The x-ray crystal structures have revealed that 4-imidazoleacetic acid HCl binds to the active site of NADH oxidoreductase with an orientation that mimics a substrate molecule. This allows it to bind tightly and disrupt enzyme activity.</p>

<p>Ethyl 5-Nitroindole-2-Carboxylate is a precursor to the anti-HIV drug Delavirdine. It is synthesized by condensation of ethyl pyruvate and urea derivative in the presence of thionyl chloride. This compound can be used as an intermediate in the synthesis of other compounds such as ethyl ester and ethyl pyruvate. The chemical reaction is carried out at room temperature using a chlorinated solvent such as methylene chloride or chloroform. Ethyl 5-nitroindole-2-carboxylate can also be used for the synthesis of other drugs, including antitumor agents.</p>

<p>5,7-Dinitroindole-2-carboxylic acid is a versatile building block that has been used as a reagent in organic synthesis. It has also been shown to be an intermediate in the preparation of 5,7-dichloroindole and other complex compounds. This compound is a reaction component for the synthesis of many useful compounds, including research chemicals and speciality chemicals. 5,7-Dinitroindole-2-carboxylic acid is soluble in most solvents and can be purified by recrystallization or chromatography. The purity can be determined by elemental analysis or nuclear magnetic resonance spectroscopy.</p>

<p>5-Bromoisatoic anhydride is a potential anticancer agent that contains nitrogen atoms. It inhibits the growth of cancer cells by binding to the enzyme acetylcholine, which is involved in the production of growth factors. The compound also inhibits the production of malonic acid, which is a metabolic disorder. 5-Bromoisatoic anhydride forms stable complexes with malonic acid and does not cause any adverse effects on normal cells.</p>

<p>Also called Skatole.  It occurs naturally in the feces of mammals and birds and is the primary contributor to fecal odour.</p>

<p>Synthon for preparation of cholinergic receptor ligands; hypotensive</p>

<p>Substrate for dealkylase.</p>

<p>Methyl indole-3-acetate is a phytochemical that inhibits the growth of cells. It has been shown to induce apoptosis in cancer cells, and also to inhibit carcinogenesis. Methyl indole-3-acetate is found at higher concentrations in the target tissue, such as the prostate gland, than in other tissues. This compound has been shown to inhibit lipid peroxidation in vitro and may be useful for the prevention of oxidative damage as well as for its antitumor activity. The effects of methyl indole-3-acetate on cell growth are related to its ability to bind with amines and uroquinase enzymes. Methyl indole-3-acetate has been shown to have anti-cancer properties in various model systems, including microbial metabolism studies.</p>

<p>5-Bromo-4-chloroindolyl 1,3-diacetate (5BCDA) is a clinical response predictor of postoperative radiotherapy. It is an acr20 response predictor for the diagnosis of chronic hepatitis C and the disease activity index in women with genital herpes. 5BCDA has been found to be effective in reducing levels of IL-17a and IL-17f, which are cytokines that are important for immune responses. 5BCDA has also been shown to be effective in treating infectious diseases such as malaria and tuberculosis.</p>

<p>N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane is a polymerase that has been developed for use in vaccines and as an agrochemical for the control of plant diseases. This enzyme has been shown to have high activity against cancer cells, including lung cancer cells and breast cancer cells. It is also autofluorescent and can be used as a cell marker in flow cytometry experiments. N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane also has antiinflammatory effects on macrophages by inhibiting the production of proinflammatory cytokines such as IL 12p</p>

<p>N,N'-Thiocarbonyldiimidazole is a potent inhibitor of the enzyme acetylcholinesterase. It is used in research as an inhibitor molecule for receptor activity and to study the mechanism of action of other drugs. N,N'-Thiocarbonyldiimidazole inhibits the production of ester hydrochloride by rat liver microsomes and muscle cell proliferation. In addition, this compound has been shown to be a protonophore that can transport protons across membranes without energy input. This can be done through Langmuir adsorption isotherm and electrochemical impedance spectroscopy.</p>

<p>Acetyl columbianetin is a natural compound, which is a type of secondary metabolite derived primarily from plant sources. This compound is part of a broader category of phytochemicals known for their diverse bioactive properties. Acetyl columbianetin is specifically sourced from certain species within the Apiaceae family, commonly found in traditional medicine.</p>

<p>1,10-Phenanthroline-2-carbaldehyde is a phenylhydrazone compound that has been shown to have anticancer activity. It is also a supramolecular complex, which means it can form hydrogen bonds and coordinate bonds with other molecules. The anticancer activity of 1,10-phenanthroline-2-carbaldehyde may be due to its ability to inhibit the growth of prostate carcinoma cells. This compound also inhibits the growth of human cervical carcinoma cells by binding to their DNA and inhibiting the synthesis of RNA and protein. 1,10-Phenanthroline-2-carbaldehyde is being studied for its potential as an inhibitor of tumor angiogenesis.<br>1,10-Phenanthroline-2-carbaldehyde has been shown to have antiplatelet aggregation effects in platelets from healthy humans as well as those with type 2 diabetes mellitus or chronic kidney disease.</p>

<p>3,3'-Diindolyl is a molecule that belongs to the class of oxindoles. Oxindoles are bioactive molecules that are formed by the reduction of 3,3'-dihydroxyindole (oxindole). The borohydride reduction of 3,3'-dihydroxyindole yields 3,3'-diindolyl. It has been shown to have anti-inflammatory properties and can be used for the treatment of inflammatory diseases such as congestive heart failure. 3,3'-Diindolyl is also an acidic compound and therefore can be used as an acidic buffer in pharmacopeia. It reacts with peroxide to form an aldehyde after oxidation. This reaction is catalyzed by sodium borohydride reduction or hydrogen peroxide. The borohydride reduction of 3,3'-diindolyl yields 2-hydroxy-1-(2-hydroxyethyl) indole (oxindole).</p>

<p>Please enquire for more information about Methyl 1-(2-chloro-4-fluorobenzyl)-3-formyl-6-methoxy-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3,4-diaza-5-(tert-butyl)-2-hydroxy-3-((4-methylphenyl)sulfonyl)tricyclo[6.4.0.0&lt;2,6&gt;]dodeca-1(8),4,9,11-tetraen-7-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hypoxanthine is a nucleoside that is found in human cells. It is synthesized from guanine by the enzyme, xanthine oxidoreductase. Hypoxanthine is also produced from xanthine by adenosine deaminase and converted back to xanthine, which can then be reused for DNA synthesis. Hypoxanthine has been shown to inhibit the growth of photosynthetic bacteria, such as Rhodopseudomonas viridis and Rhodobacter sphaeroides. This inhibition may be due to an equilibrative nucleotide effect on the folate receptor. The x-ray diffraction data collected from the chrysanthemum flower (a source of hypoxanthine) showed that hypoxanthine has a calcium salt structure.</p>

<p>2-Azaspiro[3.3]heptane HCI is a fine chemical that has many uses in research, manufacturing, and other industries. It is a versatile building block that can be used as an intermediate or reaction component for the synthesis of organic compounds. 2-Azaspiro[3.3]heptane HCI is also a speciality chemical because it has many applications in the pharmaceutical and agrochemical industries. This compound can be used as a reagent for the determination of carboxylic acids, alcohols, and amines by paper chromatography and high performance liquid chromatography (HPLC). 2-Azaspiro[3.3]heptane HCI is also useful in the synthesis of peptides and other complex compounds, such as diazepam.</p>

<p>4,4'-Dichloro-2,2'-bipyridine (4,4'-DDBP) is a polydentate ligand that has been shown to be highly cytotoxic against cancer cells. 4,4'-DDBP binds to amines in the cancer cell and uses its nucleophilic character to activate the amine by displacement of chloride ions. This leads to the production of an excited state that can be used for photodynamic therapy or as a fluorescence probe. This compound has also been shown to have operational kinetic properties in the inhibition of bilirubin oxidase.</p>

<p>(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is a carbocyclic nucleoside that has been used as a flow rate standard to measure the rate of liquid chromatography. It is an organic solvent, which has been shown to have kinetic properties in the ring opening of lactams and the hydrolysis of esters. (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one can be synthesized by reacting with a cocatalyst and a reaction time of less than 5 minutes at room temperature in a high performance liquid chromatography method or by liquid chromatography with preparative methods.br&gt;br&gt;<br>(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is used as a binding agent for</p>

<p>4-Fluoro-1H-indole-3-carbaldehyde is a chemical compound that can be used as a reagent, reaction component, or building block in the synthesis of more complex compounds. This chemical is also known as CAS No. 23073-31-6 and has high quality and purity. 4-Fluoro-1H-indole-3-carbaldehyde is useful for research purposes and can be used as a speciality chemical or a fine chemical.</p>

<p>3-Carboxy-5-(2-chlorophenyl)-1-phenylpyrazole is a white solid that is soluble in organic solvents. It is a useful scaffold that can be used as a starting material for the synthesis of complex compounds. 3-Carboxy-5-(2-chlorophenyl)-1-phenylpyrazole has been shown to be an intermediate in the synthesis of speciality chemicals and fine chemicals, such as pesticides and pharmaceuticals.</p>

<p>Columbianadin is a coumarin derivative, which is a natural compound primarily extracted from plants in the Apiaceae family, such as Angelica species. This natural product possesses a unique molecular structure characterized by the presence of a coumarin skeleton, which is responsible for its diverse biological activities.</p>

<p>5-Fluoro-3-methylindole is a reactive compound that is not soluble in water. It has a molecular weight of 288.5 and an ionization potential of 7.8 eV. 5-Fluoro-3-methylindole can act as a potent antagonist by binding to the pharmacophore, which is the three hydrogen bonding sites on the benzodiazepine receptor. This drug has been shown to be reactive with halides, nitro, and magnesium, as well as with some endogenous compounds such as nitroarenes and amides. 5-Fluoro-3-methylindole also reacts with fluorescence ligands and transfer agents.</p>

<p>(-)-Oxypeucedanin is a natural furanocoumarin, which is a type of organic compound. Furanocoumarins are derived from specific plants and are known for their complex structures and biological activities. (-)-Oxypeucedanin is sourced primarily from plants belonging to the Apiaceae family, such as Peucedanum species.</p>

<p>Geiparvarin is a cytotoxic compound, which is a plant-derived chemical with notable bioactivity. It is sourced from the roots of the Daflon plant, known for various natural compounds with potential therapeutic effects. Geiparvarin acts by interfering with cellular processes, leading to apoptosis in malignant cells. This mode of action is particularly significant in the study and development of anticancer therapies.</p>

<p>Phosphodiesterase type 3 inhibitor; positive inotropic agent; vasodilatory</p>

<p>5-Ethylindole-2-carboxylic acid is an organic compound that is a decarboxylation product of indole. It can be obtained by catalytic dehydrogenation of ethyl ester or 5-ethylindole-2-carboxylic acid. It has been shown to inhibit the growth of bacteria and fungi, as well as to have anti-inflammatory properties.</p>

<p>L-5-Methyltetrahydrofolate calcium is also known as calcium levomefolate; N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, calcium salt; and L-5-MTHF. L-5-Methyltetrahydrofolate calcium is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation. L-5-Methyltetrahydrofolate calcium is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.</p>

<p>Indole-3-glyoxylamide is a synthetic compound that was originally developed as a potential anti-cancer drug. It has been shown to inhibit glycogen synthase kinase 3 (GSK-3) and thereby reduce the production of proinflammatory cytokines in bowel disease. Indole-3-glyoxylamide also inhibits inflammatory bowel disease by inhibiting secretory phospholipase A2, which prevents the release of arachidonic acid from phospholipids. This synthesis is required for the production of prostaglandins and leukotrienes, which are involved in the inflammatory process. The compound has been shown to have immunomodulatory effects in chronic bronchitis, with an inhibitory effect on neutrophil chemotaxis, macrophage activity, and cytokine production. Indole-3-glyoxylamide has also been shown to be effective against cancer cells in vitro and in vivo animal models. It is metabolized through</p>

<p>8-Hydroxyquinoline-2-carboxylic acid is a 3-hydroxyanthranilic acid derivative that is often used as a biomarker of urine. The 8OHQA can be synthesized from 3-hydroxyanthranilic acid by the action of xanthine oxidase and hydrogen peroxide, and it has been shown to be an inhibitor of protein synthesis. This inhibition may be due to its ability to form hydrogen bonds with the hydroxyl group on the ribose side chain and its ability to coordinate with metals. 8OHQA has been shown to have anti-inflammatory effects in bladder cancer cells, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>Fraxidin is a naturally occurring compound, specifically an O-methylated coumarin, which is derived from certain plant sources such as the fruits of the ash tree. It is primarily obtained through the processing of various plant materials within the Rutaceae family. The mode of action of Fraxidin involves the inhibition of oxidative damage due to its capacity to scavenge free radicals, thus leading to potential antioxidant properties in biological systems.</p>

<p>(8S,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,-15,-16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl propanoate is a pesticide that is classified as a pyrethroid. It has been shown to be an insecticide that binds to cholinergic receptors in the nerve synapses of insects and disrupts transmission of nerve impulses. This allows the insect's nervous system to recover from the initial attack. The molecule has also been shown to bind to other proteins that have been identified as targets for pesticide interaction.</p>

<p>Plant hormone; auxin; inducer of root development; used in plant rooting</p>

<p>5-Methoxy-2-methylindole is an organic solvent that has been shown to have a wide range of bioactive properties. It is used in the production of acetylcholine, which is an important neurotransmitter. 5-Methoxy-2-methylindole also reacts with chloride ions, which may be an important factor when considering the life cycles and bioactive substances of this molecule. The reaction yield depends on the pH of the solution. 5-Methoxy-2-methylindole can undergo chlorination reactions to form polychlorinated derivatives, which are used as petrochemicals. This molecule also has retinoid properties and can act as a proton donor or acceptor depending on whether it is protonated or deprotonated.</p>

<p>Isatin bis-cresol is a silicon-containing compound that can be used as a viscosity modifier and stabilizer in polymers. Isatin bis-cresol has shown resistance to degradation by water, alkali, and acid. It also has a high formation rate and can be used for the production of functionalized polymers such as polycarbonates or phosphonium salts. Isatin bis-cresol is insoluble in water but soluble in organic solvents, which makes it an ideal candidate for use in transesterification reactions. Isatin bis-cresol contains three functional groups: phenolic (OH), carboxylic acid (COOH), and alcohol (OH).</p>

<p>6-Methylmercaptopurine is an important metabolite of 6-methylmercaptopurine, which is a vital component of the nucleotide synthesis pathway. It is used in analytical methods to determine levels of nucleotides, as well as in biological studies for its effect on autoimmune diseases. 6-Methylmercaptopurine can inhibit replication by inhibiting the methyltransferase enzyme.</p>

<p>7-Ethylindole-3-glyoxylic acid ethyl ester is a versatile building block that can be used in the synthesis of complex compounds. It is a useful intermediate in the synthesis of pharmaceuticals, which can also be used as a reagent and speciality chemical. The compound has been shown to have high quality and is a useful scaffold for the synthesis of new compounds.</p>

<p>5-Methoxyindole is a chemical compound that is soluble in water. It has been shown to inhibit tumor growth and induce apoptosis, as well as inhibit the expression of glycogen synthase kinase-3. The structure of 5-methoxyindole was determined by NMR spectroscopy and FT-IR spectroscopy. The compound has been observed to exhibit fluorescence properties at a wavelength of 490 nm when it is excited with UV light. A copper complex of 5-methoxyindole was studied using molecular modeling and FT-IR spectroscopy, which revealed that it can undergo nucleophilic attack by hydrogen bond formation or an acid/base reaction to form a new hydrogen bond. This study also found that 5-methoxyindole is able to form hydrogen bonds with its neighboring molecules, which may contribute to its high solubility in water.</p>

<p>4-Hydroxycoumarin is a synthetic organic compound, which is a derivative of coumarin. This compound derives from a benzopyrone structure, specifically known as a precursor in the synthesis of various anticoagulant agents. Its mode of action involves the inhibition of the enzyme vitamin K epoxide reductase. This inhibition subsequently decreases the synthesis of active clotting factors II, VII, IX, and X by preventing the regeneration of reduced vitamin K.</p>

<p>3-Quinuclidinol is an alkaloid that is found in the bark of Erythroxylum coca, a plant that has been used for centuries to combat hunger and altitude sickness. It is also found in the leaves of various plants such as khat, betel nut and tea leaves. 3-Quinuclidinol is a nicotinic acetylcholine receptor agonist, which means it stimulates the receptors in the brain that are responsible for transmitting messages from one nerve cell to another. 3-Quinuclidinol also activates certain types of protein kinase enzymes, which play a role in regulating metabolism.</p>

<p>2,2'-Bipyridine-6,6'-dicarboxylic acid is a molecule that has an acidic functional group. It has been found to have a molecular weight of 220.2 g/mol and is soluble in water at elevated temperatures. 2,2'-Bipyridine-6,6'-dicarboxylic acid has been shown to be photoprocessable in the presence of sodium carbonate as a catalyst. The reaction rate can be increased by adding a diluent to the solution or by using linear models.</p>

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<p>5,7-Dimethoxycoumarin is a naturally occurring coumarin derivative, which is primarily sourced from various plant species, most notably those belonging to the Apiaceae and Rutaceae families. This compound is characterized by the presence of methoxy groups at the 5 and 7 positions on the coumarin core structure. These structural features contribute to its biological activity by influencing its interaction with various biomolecular targets.</p>

<p>Poncimarin is a citrus-derived flavor compound, which is extracted from the peels of citrus fruits. Its mode of action involves mimicking natural citrus flavors, providing authentic taste profiles through a combination of volatile compounds that resemble those found in fresh citrus. The primary application of Poncimarin lies in its utilization as a flavoring agent in the food and beverage industry. It is incorporated to enhance the sensory attributes of products like beverages, confectioneries, and baked goods, delivering a refreshing citrus note that is both recognizable and appealing. Poncimarin's efficacy is attributed to its ability to integrate seamlessly with the existing flavor matrices of these products, ensuring a balanced and natural sensory experience. Its use extends to applications requiring stable, long-lasting flavor profiles, contributing to product innovation and development within sensory science.</p>