Toxicología

<p>Applications Nitrendipine-d5 is the isotope labelled analogue of Nitrendipine (N490150), a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.<br>References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983),<br></p>

<p>Applications A metabolite of Duloxetine.<br>References Lantz, R.J., et al.: Drug Dispos. Metab., 31, 1142 (2003), Detke, M., et al.: J. Clin Psy., 63, 308 (2002), Bymaster, F.P., et al.: Bioorg. Med., Chem. Lett., 13, 4477 (2003),<br></p>

<p>Stability Hygroscopic<br>Applications Labelled Amisulpride (A633250). Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>

<p>Applications 2,6-Difluorobenzamide (CAS# 18063-03-1) is a useful building block used in the synthesis of (E)-3-methyleneisoindolin-1-ones via oxidative annulation acrylates.<br>References Laha, J. K.; et al.: J. Org. Chem., 82, 7346 (2017).<br></p>

<p>Stability Light Sensitive<br>Applications Amidotrizoic Acid Dihydrate is used as a density gradient reagent for blood cell seperation. Diagnostic aid (radiopaque medium).<br>References Kalmer, J.R., et al., J. Immunol. Methods, 110, 275 (1988), Wang, Y., et al.: Br. J. Radiol., 170, 1229 (1997), Wong, V., et al.: Eur. J. Pharmacol., 433, 135 (2001).<br></p>

<p>Applications A by-product of Fluorescein.<br>References Ames, B., et al.: Mutation Res., 31, 347 (1975),<br></p>

<p>Applications A new benzodiazepine derivative as a new anti-anxiety drug. Ethyl Loflazepate and its metabolite were compared with those of Diazepam (D416855), Nitrazepam (N490140) and Lorazepam (L469850). The anticonflict effect of Ethyl Loflazepate was slightly more potent than that of Diazepam and much more potent than that of Lorazepam. Controlled substance.<br>References Cano J.P., et al.: J. Chromatogr., 226, 413 (1981), Tanaka M., et al.: Clin. Neuropharmacology, (1985), 8,  271 (1985),<br></p>

<p>Applications Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.<br>References Barchas, et al.: Nature, 214, 919 (1967), Glass, J.D., et al.: Science, 214, 821 (1981),<br></p>

<p>Applications A isothiazolidin-3-one derivative as antimicrobial. It was tested for inhibition of PCAF activity. 5-Chloroisothiazolinones showed the most potent inhibition of PCAF.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sadhale, P.P., et al.: J. Biol. Chem., 279, 33716 (2004), Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006),<br></p>

<p>Applications 3-Hydroxystearoylcarnitine Hydrochloride is found in overweight patients.<br>References Rodriguez-Gutierrez, R., et. al.: J. Int. Society Sports Nutrition, 9, 22, (2012)<br></p>

<p>Applications 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyloctan-1-ol Ester is a possible metabolite of the di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) monoester (MINCH).<br>References Koch, H., et al.: Arch. Toxicol., 87, 799 (2013)<br></p>

<p>Applications Labelled Octopamine (O239750). A biogenic amine that is the phenol analog of Noradrenaline. It is a neurosecretory product found in several vertebrates and invertebrates. Adrenergic.<br>References Pisano, et al.: Biochim. Biophys. Acta., 43, 566 (1960), Breen, C.A., et al.: Nature, 303, 716 (1983)<br></p>

<p>Applications Pyribambenz-Propyl is used in methods and formulations for preventing downward migration of agricultural materials.<br>References Essig, Kenneth J., et al.:PCT Int. Appl., (2020);<br></p>

<p>Applications Coumatetralyl is used as an anticoagulant rodenticide. Coumatetralyl is widely used to control rodent populations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jones, A., et al.: Bull Environ. Contain Toxicol., 56, 8 (1996), Brakes, C., et al.: J. Appl. Ecol., 42, 118 (2005), Giraudoux, P., et al.: Environ. Res., 102, 291 (2006),<br></p>

<p>Applications Diclosulam is used as a broadleaf herbicide that is used to control weeds in soybean and peanut crops. Diclosulam is applied either preplant or preemergence in order to maintain maximum control of weed growth.<br>References Grichar, W., et al.: Crop Protect., 23, 1145 (2004); Lancaster, S., et al.: Proc. Am. Peanut Res. Ed. Soc., No vol. given, No pp. given, (2006); Sheppard, B., et al.: Proc. South. Weed Sci. Soc., 50, 161 (1997)<br></p>

<p>Applications Used as a broad range pesticide against insects, fungi, vegetation and bacteria. It has become a common environmental contaminant and probable human carcinogen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gulcan, H., et al.: Chem. Res. Toxicol., 21, 1503 (2008), Toropov, A., et al.: Bioorg. Med. Chem., 16, 5999 (2008), Franco, A., et al.: Envir. Toxicol. Chem., 28, 2018 (2009), Jensen, S., et al.: J. Agric. Food Chem., 57, 5872 (2009),<br></p>

<p>Applications Tianeptine Sodium Salt is a tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.<br>References Malen, C., et al.: Experientia, 28, 811 (1972),<br></p>

<p>Applications Labelled trichloroethylene metabolite<br>References Werner, M., et al.: Chem. Res. Toxicol., 9, 41 (1996), Bruning, T., et al.: Toxicol. Sci., 41, 157 (1998), Newman, D., et al.: Drug Metab. Disposition, 35, 43 (2007),<br></p>

<p>Applications Methyclothiazid, is derivative of Hydrochlorothiazide (H714560), which is a diuretic used in the hospital or for personal use to promote excess fluid associated with congestive heart failure. It is also used as an antihypertensive.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981),<br></p>

<p>Applications Androsterone glucuronide (ADT-G) is one of the major circulating C19-steroid metabolites in humans. Exaggerated Androsterone (A637535) metabolism is observed in hyper-androgenic as well as in some normo-androgenic women with acne and androsterone glucuronide could be a marker in differentiating acne and hirsutism in hyperandrogenic women.<br>References Thompson, D.L. et al.: Clin. Endocrinol., 32, 283 (1990); Stener-Victorin, E. et al.: J. Clin. Endocrinol. Metab., 95, 810 (2010);<br></p>

<p>Applications Dicamba is a herbicide. Dicamba functions by increasing plant growth rate. At sufficient concentrations, the plant outgrows its nutrient supplies and dies. Dicamba has been approved by the EPA for use on genetically modified soybeans and cotton.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br>References Oehler, D.D., et al.: J. Agric. Food Chem., 28, 685 (1980); Griffin, J., et al.: Weed Techno., 27, 696 (2013); Chem. and Eng. News, Nov. 14, 2016, p. 17<br></p>

<p>Applications Antitussive. Chain between 6 and 17 units of ethylene glycol with the major product containing 10 units.<br>References Scholtissek, C., et al.: Antiviral Res., 38, 213 (1998), McGovern, S., et al.: J. Med. Chem., 45, 1712 (2002), Regenthal, R., et al.: Hum. Exp. Toxicol., 21, 343 (2002),<br></p>

<p>Applications A fluorimetric substrate for cytochrome P450 IAI. Inhibits vasorelaxant responses to acetylcholine.<br>References Donato, M.T., et al.: Anal. Biochem., 213, 29 (1993), Oyekan, A.O., et al.: J. Pharmacol. Exp. Ther., 268, 262 (1994)<br></p>

<p>Applications N-Octanoyl-d15-glycine is labelled N-Octanoylglycine (O239735) which is a derivative of Glycine (G615990) and is an amphiphilic lipoamino acid commonly used in cosmetics for its antibacterial properties. N-Octanoylglycine is the active ingredient in products designed to treat seborrheic dermatitis on the scalp and acne prone skin.<br>References Georgalas, A.: Cosmet. Toiletries, 127, 96 (2012); Nakamura, S.: Frag. J., 39, 36 (2011)<br></p>

<p>Applications An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>

<p>Applications A metabolite of Aniline. Arylamines are predominantly conjugated by constitutive enzyme forms in the liver.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Axelrod, J., et al.: J. Biol. Chem., 232 835 (1958), Lilienblum, W., et al.: Biochem. Pharmacol., 33, 2041 (1984),<br></p>

<p>Stability Hygroscopic<br>Applications Muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006),<br></p>

<p>Applications Metconazole is a conazole based fungicide used for the control of black sigatoka disease on bananas. Metconazole acts primarily as an inhibitor of ergosterol biosynthesis which interferes with the synthesis of fungal cell membranes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cools, H.J., et al.: Pest. Manage. Sci., 68, 1034 (2012); Nam, M.H., et al.: Res. Plant. Disease., 17, 295 (2011);<br></p>

<p>Applications Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996),<br></p>

<p>Applications KU-0058948 is a poly (ADP-ribose) polymerase (PARP) inhibitor. Studies show that KU-0058948 is a potent agonist that activates transfected extracellular signal-regulated kinase 8 (ERK8) in cells. KU-0058948 induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro<br>References Klevernic, I.V. et al.: FEBS Lett., 583, 680 (2009); Gaymes, T.J. et al.: Haematologica, 94, 638 (2009);<br></p>

<p>Applications Rolitetracycline is a tetracycline antibiotic that may be given intravenously or intramuscularly in serious bacterial infections when oral administration is not practicable.<br>References Choudhary, S., et al.: Chem. Biol. Drug. Des., 80, 693 (2012); Ejim, L., et al.: Nature. Chem. Biol., 7, 348 (2011); Giorgetti, S., et al.: J. Biol. Chem., 286, 2121 (2011);<br></p>

<p>Applications (2S,3S)-Hydroxybupropion hydrochloride (CAS# 106083-71-0) is a useful research chemical compound.<br></p>

<p>Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>

<p>Applications Oxymatrine-d3, is a labeled analogue of Oxymatrine (O876300), an anti-tumor agent triggering apoptosis in human leukemia cells.<br>References Liu, J. et al.: Tumor Biol., 35, 5409 (2014); Wang, C. et al.: Am. J. Chinese Med., 42, 543 (2014);<br></p>

<p>Stability Light Sensitive<br>Applications S-Hydroprene, is an insect growth regulator used as an insecticide. It is used against cockroaches, beetles, and moths.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Environmental Protection Agency, Federal Register, 62, 61645 (1997); Bell, H. A., et al.: J. Stored Produc. Res., 35, 117 (1999);<br></p>

<p>Applications A labelled opioid analgesic. Used as a substitute to morphine for postoperative pain in children.<br>References Lundeberg, S. et al.: Acta Anaesthesiol. Scand., 54, 435 (2010); Christensen, T. et al.: Neurosci. Res. Comm., 26, 77 (2000);<br></p>

<p>Applications Calcitonin, Salmon is a calcium regulating hormone which exhibits hypocalcaemic and hypophosphatemic properties.<br></p>

<p>Applications Labelled Doxazosin (D537500). Doxazosin is a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.<br>References Elliott, H.L., et al.: Brit. J. Clin. Pharmacol., 13, 699 (1982), de Leeuw, P.W., et al.: Eur. J. Clin. Pharmacol., 23, 397 (1982),<br></p>

<p>Applications Bentazon-d7 is deuterium labelled Bentazon (B120580), which is a herbicide.<br>References Ghirardello, D., et al.: Environ. Sci. Technol., 44, 9010 (2010), Frihauf, J., et al.: Weed Technol., 24, 262 (2010), Rotroff, D., et al.: Toxicol. Sci., 117, 348 (2010),<br></p>

<p>Applications A muscarinic receptor used as nootropic agent.<br>References Wolf-Pflugmann, M., et al.: Arzneim-Forsch./Drug Res., 39(1), 5, 539 (1989),<br></p>

<p>Applications Ezetimibe-d4 is the labeled analogue of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997); van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>

<p>Applications Systemic agricultural fungicide.<br>References Ozer, N., et al.: J. Phytopathol., 158, 744 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),<br></p>

<p>Applications Picoxystrobin is a methoxyacrylate strobilurin fungicide designed for the control of wide range of cereal diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Walorczyk, S., et al.: J. Chromatograph. A., 1251, 219 (2012); Roszko, M., et al.: J. Am. OIl. Chemist. Soc., 89, 389 (2012);<br></p>

<p>Applications Ethoprophos is an organophosphate non-systemic nematicide and soil insecticide (1). Ethoprophos is an acetylcholinesterase (AChE) inhibitor (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Used as a standard for Pesticide detection. Ethoprophos is also useful in cannabis testing kits as a component of pesticide mixes (P698230).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Wing, K. et al.: Pest. Biochem. Physiol. 1984. Feb:21(1) pp22-302. Opperman, C. et al.: J. Nematol. 1990 Oct;22(4):481-83. Nordmeyer, D. et al.: Plant. Dis. J. 1985 Jan:69: 67-69<br></p>

<p>Applications Controlled substance (opiate). Used in treatment of opioid dependence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bishara, R.H., et al.: Anal. Profiles Drug Subs., 3, 365 (1974), Senay, E.C., et al.: Int. J. Addict., 20, 803 (1985), Inturrisi, C.E., et al.: Clin. Pharmacol. Ther., 41, 392 (1987), Sees, K.L., et al.: J. Am. Med. Assoc., 283, 1303 (2000),<br></p>

<p>Applications A cell-permeable fluorescent probe selective for Zinc. Fluorescence: max. Em. l = 515nm<br>References Koh, J., et al.: Science, 272, 1013 (1996), Suh, S., et al.: Brain Res., 852, 268 (2000), Finney, L., et al.: Science, 300, 931 (2003), Lopantsev, V., et al.: Neuroscience, 116, 237 (2003), Kambe, T., et al.: Cell Mol. Life Sci., 61, 49 (2004),<br></p>

<p>Applications A fodder additive for poultry used to prevent coccidiosis infections. Antiprotozoan drug.<br>References Morrison, W.D. et al.: Poult. Sci., 46, 391 (1967); Davis, J.L. et al.: Vet. Pharmacol. Therap., 9, 1145 (2009);<br></p>

<p>Applications A glucuronide of (Z)-4-Hydroxy Tamoxifen (or trans-4-hydroxytamoxifen), an active metabolite of Tamoxifen (T006000).<br>References Beaulieu, M., et al.: J. Biol. Chem., 271, 22855 (1996), Green, M., et al.: Drug Metab. Dispos., 26, 860 (1998), Nishiyama, T., et al.: Biochem. Pharmacol., 63, 1817 (2002),<br></p>

<p>Applications Antiallergic, antiasthmatic(inhalate). Anti-inflammatory(topical).<br>References Laube, B., et al.: J. Allergy Clin. Immunol., 101, 475 (1998), Harrison, L., et al.: Eur. J. Clin. Pharmacol., 58, 191 (2002) , Maneechotesuwan, K., et al.: J. Allergy Clin. Immunol., 121, 43 (2008).<br></p>

<p>Applications Deuterated Irinotecan, a DNA topoisomerase inhibitor.<br>References Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987), Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993)<br></p>

<p>Applications Labelled Octylonium Bromide (O293250). Octylonium bromide is an antimuscarinic. Octylonium bromide is a platelet-activating factor antagonist as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agent. Octylonium bromide is used as an antispasmodic.<br>References Manzini, S., et al.: Drugs Exp. Clin. Res., 14, 265 (1988), Emonds-Alt, X., et al.: Eur. J. Pharmacol., 250, 403 (1993), Sutton, J., et al.: Eur. J. Clin. Pharmacol., 52, 365 (1997), Catalioto, R., et al.: Br. J. Pharmacol., 123, 81 (1998),<br></p>

<p>Applications Clofentezine is a mite growth regular and an tetrazine based acaricide. Clofentezine is used in agriculture for the protection of ornamentals, food and non-food crops in the field.Used as a standard for Pesticide detection. Clofentezine is used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bakirci, G.T., et al.; Food. Chem., 135, 1901 (2012); Ay, R., et al.: Insect. Sci., 18, 503 (2011);<br></p>

<p>Applications A metabolite of Estradiol (E888000).<br>References Agasan, A., et al.: J. Immunol. Methods., 177, 251 (1994), Stone, R., et al.: Science, 265, 308 (1994), Tacey, R., et al.: J. Pharm. Biomed. Anal., 2, 1303 (1994),<br></p>

<p>Applications Inhibits the enzyme HMG-CoA reductase in vitro.<br>References Endo, A., et al.: J. Antibiot., 32, 852 (1979), Alberts, A.W., et al.: Drug Invest., 2 (Suppl. 2), 9 (1990), Kuroda, M., et al.: Biochim. Biophys. Acta, 486, 70 (1977),<br></p>

<p>Applications Anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Becker, A., et al.: J. Int. Med. Res., 8, 333 (1980), Child, R.G., et al.: Arzneim.-Forsch., 30, 695 (1980), Bolte, H.F., et al.: Arzneim.-Forsch., 30, 721 (1980).<br></p>

<p>Applications Labelled Clonazepam (C587080). Antiepileptic agent with anxiolytic and antimanic properties. Anticonvulsant.This is a controlled substance (depressant).<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>

<p>Applications Nemonapride is a selective dopamine D2 receptor antagonist. Nemonapride is used as an antipsychotic.<br>References Yamamoto, M., et al.: Neuropharmacology, 21, 945 (1982), Grewe, C.W., et al.: Eur. J. Pharmacol., 81, 149 (1982), Satoh, K., et al.: Int. Clin. Psychopharmacol., 11, 279 (1996)<br></p>

<p>Applications Phosphonomethanol has been used in the investigation on the stereochemistry of 2-Hydroxyethylphosphonate Dioxygenase.<br>References Whitteck, J.T., et al.: J. Am. Chem. Soc., 133, 4236 (2011); Duca, J.S., et al.: Chem. Materials., 12, 3821 (2000);<br></p>

<p>Applications 6-Benzylaminopurine can be used as reagent/reactant in pharmacological activity and synthesis preparation for modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71.<br>References Drenichev, M., S.: Eur. J. Med. Chem., 111, 84-94 (2016);<br></p>

<p>Applications Labelled 4-Aminohippuric Acid is used in the measurement of renal plasma flow as a diagnostic tool which may be applied towards kidney disorders.<br>References Phillips, R. et al.: Am. J. Physiol., 152, 523 (1948);<br></p>

<p>Stability Hygroscopic<br>Applications Selective serotonin 5HT3, receptor antagonist; structurally different from Ondansetron (O655000), Granisetron (G780000). Antiemetic.<br>References Miyata, K., et al.: J. Pharmacol. Exp. Ther., 259, 15 (1991), Miura, H., et al.: Biomed. Chromatogr., 8, 103 (1994), Tabata, H., et al.: Arzneim.-Forsch., 45, 760 (1995),<br></p>

<p>Applications Tetrasul is a chlorinated diphenyl sulfide aracacide. Tetrasul is used for the control of mites and other pests in food and gardening crops.<br>References Hansen, T. et al.: Tids. Plant., 74, 618 (6970); Dittrich, V.: Zeitsch. Angew. Entomol., 61, 240 (1968);<br></p>

<p>Applications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.<br>References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)<br></p>

<p>Stability Moisture Sensitive<br>Applications Leptophos is an organophosphorus pesticides which exhibits a stronger endocrine disruption than its (+)form in JEG-3 cell.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lu, Y., et al.: Zhejiang Gongye Daxue Xuebao, 40, 152-156 (2012)<br></p>

<p>Applications A labelled metabolite of the pesticide Glyphosphate (G765000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Siehl, D.L. et al.: J. Biol. Chem., 282, 11446 (2007); Env. Prot. Agen. EPA: Fed. Reg., 74, 67129 (2009);<br></p>

<p>Applications Imidacloprid-urea is a metabolite of Imidacloprid (I275990), a neonicotinoid; the active ingredient in certain neuro-active insecticides. Used in pest control.<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009); Aregahegn, K. et al.: Env. Sci. Tech., 51, 2660 (2017);<br></p>

<p>Applications Contact herbicide used also to produce desiccation and defoliation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brian, et al.: Nature, 181, 446 (1958), Gaines, T.B., et al.: Fundam. Appl. Toxicol., 7, 299 (1986),<br></p>

<p>Stability Toxic<br>Applications Isotopopically Labelled analogue of Captan (C175725), which is an acetylcholinesterase inhibitor acting as a fungicide (1), often added to pesticide mixtures to control diseases among fruits and vegetables. Detected through various analytical techniques involving pesticide residues such as MS-PD and GC-MS (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Also used in cannabis testing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Afful, S. et al.: Res. J. App. Sci. Eng. Tech. (2010) 14 Jul:2(6) 592-52. Engelen, K. et al.: J. Proteome. Res. 2010 Oct 1;9(10):4919-263. Lagunas-Allue, L. et al.: Anal. Bioanal. Chem. 2010 Oct;398(3):1509-23<br></p>

<p>Applications Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources.Insect repellent.<br>References Boeckh, J., et al.: Pestic. Sci., 48, 359 (1996), Yap, H.H., et al.: J. Vector Ecol., 23, 62 (1998),<br></p>

<p>Applications Herbicides for weed control in wheat.<br>References Aliverdi, A., et al.: Weed Biol. Management, 9, 292 (2009), Hochberg, O., et al.: Weed Res., 49, 37 (2009), Liu, B., et al.: J. Agric. Food Chem., 58, 2673 (2010),<br></p>

<p>Applications Phenylguanidine anthelmintic. Anthelmintic.<br>References Williams, J.C., et al.: Am. J. Vet. Res., 46, 2188 (1985), Delatour, P., et al.: J. Vet. Pharmacol. Ther., 9, 230 (1986),<br></p>

<p>Applications Chlorimuron-ethyl-d5 is a labeled analogue of Chlorimuron-ethyl (C371273), which is used in weed control method as herbicide.<br>References Sada, Y., et al.: PCT Int. Appl. 45 pp. (2020)<br></p>