Alcoholes

<p>Applications 4,4'-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein.<br>References Okun, I. et al.: J. Biomol. Screen., 11, 694 (2006);<br></p>

<p>Applications Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.<br>References Ebeling, P., et al.: Lancet, 343, 1479 (1994); Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994); Ramachary, D.B., et al.: RSC Advances, 3, 13497-13506 (2013); Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977);<br></p>

<p>Applications 3-O-tert-Butyldimethylsilyl-cholest-5-ene-3-ol 24-(2-hydroxyisopropyl) 24-Phenyl Sulfinate is an intermediate in the preparation of Campesterol (C155360).<br></p>

<p>Applications 1-Nonanol is an chain fatty acid alcohol that naturally occurs in oil of orange. 1-Nonanol is used in the manufacture of artificial lemon oil.<br>References Tabilio, M.R., et al.: Food Chem., 140, 375 (2013); Thomas, C., et al.: Food. Chem., 139, 432 (2013);<br></p>

<p>Applications 2-O-Hexadecyl Glycerol is an important research chemical where chiral-phase HPLC/MS is used to identify its alkyl group.<br>References Yamashina, T., et al.: Bunseki Kagaku, 55, 643-650 (2006)<br></p>

<p>Applications 3,4-Diaminophenol (cas# 615-72-5) is a useful research chemical.<br></p>

<p>Applications 4-(phenylsulfanyl)phenol (cas# 5633-55-6) is a useful research chemical.<br></p>

<p>Stability Unstable in Solution, Air Sensitive<br>Applications 2-HYDROXYTHIOPHENOL (cas# 1121-24-0) is a useful research chemical.<br></p>

<p>Applications 1,11-Dodecadien-4-ol is an intermediate in the synthesis of 3-Hydroxy Sebacic Acid (H953770), which is a normal urinary 3-hydroxydicarboxylic acid metabolite and can be elevated in patients with peroxisomal disorders such as Zellweger syndrome.<br>References Bernier, F., et al.: Neurology, 59, 1406 (2002), Boekema, E., et al.: J. Biol. Chem., 282, 1 (2007), Goodacre, R., et al.: Metabolomics, 3, 231 (2007),<br></p>

<p>Applications 3-Furanmethanol (cas# 4412-91-3) is a useful research chemical.<br></p>

<p>Applications N-(Trifluoroacetyl)hexanolamine (cas# 40248-34-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-[(9Z)-9-Octadecenyloxy]-1,3-propanediol, which is an endogenous cannabinoid receptor ligand.<br>References Suhara, Y. et al.: Chem. Pharm. Bull., 48, 903 (2000);<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications (S,S)-2,3-Butanediol is the (S,S)-isomer of 2,3-Butanediol (B690020), a naturally occurring compound found in cocoa butter.<br>References Wang, Yu., et al.: J. Biological. Chem., 289, 6080 (2014); Cheng, C., et al.: J. Org. Chem., 78, 8562 (2013);<br></p>

<p>Applications 3-[(Dimethylamino)carbonyl]phenol can be used in the synthesis of novel purine and bicyclic pyrimidine, which are factor Xa inhibitors, and also have high selectivity over thrombin and trypsin.<br>References Buckman B. O., et al.: Bio. Med. Chem. Let., 8, 2235 (1998)<br></p>

<p>Applications 1-Mesyl-2-azidoethanol is an intermediate in the synthesis of dopamine D1/D3 heterodimer to Investigate Hetero-Oligomer binding properties.<br>References Hounsou, C., et al.: ACS. Chem. Biol., 10, 466 (2015);<br></p>

<p>Applications 4-Aminophenethyl Alcohol, is a building block that can be used in the synthesis of various compounds, such as in synthesis of 4-aminostyrene, and in functionalization of graphene nanoplatelets.<br>References Li L, et al.Polymer Journal 33(4), 364-370; Hagiwara T, et al. Macromolecules 24(26), 6856-6858, (1991);<br></p>

<p>Applications 3,5-Dibenzyloxybenzyl alcohol (cas# 24131-31-5) is a useful research chemical.<br></p>

<p>Applications (E)-5-(3,5-Bis(benzyloxy)phenyl)pent-4-en-2-ol is an intermediate used in the synthesis of 4''-Hydroxycannabidiol (H824830), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 4''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>

<p>Stability Light Sensitive, Volatile<br>Applications 1,5-Hexadien-3-ol is a reactant used in the synthesis of laurencia metabolite obtusenye.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Crimmins, M.T., et al.: J. Am. Chem. Soc., 125, 7592-7595 (2003)<br></p>

<p>Applications Leuco-2,6-dichlorophenolindophenol is the reduced form of DCIP and has been used to measure photocatalytic oxidation.<br>References Krysa, J.; et al.: Catalysis Today, 240, 132 (2015). Kafizas, A.; et al.: Chemistry - A European Journal, 18, 13048 (2012).<br></p>

<p>Applications 2-Biphenylmethanol is a useful reactant in organic synthesis.<br>References Li, Zheng, et al.: Bioorg. &amp; Med. Chem., 25(24), 6647-6652 (2017);Shi, Guangfa, et al.: Org. Let., 18(12), 2958-2961 (2016)<br></p>

<p>Applications cis-4-Decen-1-ol is a reactant in the synthesis of epoxyisoprostanes as antiinflammatory agents.<br>References Egger, J., et. al.: Angew. Chem. Int. Edit., 52, 5382 (2013)<br></p>

<p>Applications DL-2-Amino-1-pentanol is a useful intermediate for organic synthesis. It is used in the preparation of amino-substituted pyrimidine derivatives and other aminoethanethiol derivatives with potential antiradiation properties.<br>References Yoo, K. H., et al.: Korean J. Med. Chem., 9, 83 (1999); Fernandez, S., et al.: Synthesis, 9, 713 (1991)<br></p>

<p>Applications 4-(2,4,4-trimethylpentan-2-yl)benzene-1,2-diol (cas# 1139-46-4) is a useful research chemical.<br></p>

<p>Applications 2-(Tetrahydro-2H-pyran-3-yl)ethanol (cas# 1050493-77-0) is a useful research chemical.<br></p>

<p>Applications 2-Amino cyclopentanol<br></p>

<p>Applications 4-PROPOXYPHENOL (cas# 18979-50-5) is a useful research chemical.<br></p>

<p>Applications 1-(3,5-Bis(benzyloxy)phenyl)pentan-2-ol is an intermediate for the synthesis of 2''-Hydroxycannabidiol (H824820), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 2''-Hydroxycannabidiol can be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>

<p>Stability Unstable in aqueous media<br>Applications 1H-indazol-1-ylmethanol (cas# 1006-29-7) is a useful research chemical.<br></p>

<p>Applications (S)-3-Aminobutan-1-ol can be used as an intermediate in the preparation of compounds having HIV integrase inhibitory activity.<br>References Johns, B. et al.: J. Med. Chem., 56, 5901 (2013);<br></p>

<p>Applications 2-(2-Cyclopenten-1-yl)-phenol is an intermediate used in the synthesis of (S)-Penbutolol Sulfate (P220505), which is an isomer of Penbutolol (P220500), a β-adrenoceptor antagonist. Antihypertensive.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>

<p>Applications 2-Cyclohexen-1-Ol (cas# 822-67-3) is a useful research chemical.<br></p>

<p>Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.<br></p>

<p>Applications 3,​7-​Dimethyl-​1-​octanol is a useful organic reactant/reagent.<br>References Dantignana, V., et al.: ACS Cent Sci., 3, 1350-58 (2017); Jana, S., et al.: Org, Lett., 19, 746-49 (2017);<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications 4-Acetamidobenzyl Alcohol is a useful research chemical, a metabolites of a blocked chloramphenicol producer.<br>References Lewis, E. A., et al.: J. Nat. Prod., 66, 62 (2003)<br></p>

<p>Applications Thietan-3-ol (cas# 10304-16-2) is a useful research chemical.<br></p>

<p>Applications pentane-2,3-diol (cas# 42027-23-6) is a useful research chemical.<br></p>

<p>Applications Cyclopropylmethanol used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones<br>References Hu, E. et al.: Bioorg. Med. Chem. Lett., 22, 6938 (2012);<br></p>

<p>Applications N-(2-Hydroxyethyl)tetracosanamide acts as a crude oil emulsifier.<br>References Zhiqiang, J., et al.: Fami Zhu Shen., 5 (2016)<br></p>

<p>Stability Air Sensitive<br>Applications Thiol-PEG2-acid (cas# 1379649-73-6) is a useful research chemical.<br></p>

<p>Applications 2,5-Dimethylbenzene-1,4-diol is an intermediate used in the synthesis of β-Tocopherol (Racemic Mixture) (T625170), which is one of the naturally occurring forms of Vitamins E and is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.<br>References Bianchi, G., et al.: Eur. J. Lipid Sci. Technology, 105, 229 (2003), Sakouhi, F., et al.: Food Chem., 108, 833 (2008)<br></p>

<p>Applications 4-{[(p-Fluorophenyl)imino]methyl}phenol is used in the preparation of benzylacetones which promote anti-fungal activity.<br>References Sandhar, R. et al.: J. Ind. Council Chem., 22, 32 (2005);<br></p>

<p>Applications (2R)-2-(dimethylamino)propan-1-ol (cas# 55197-05-2) is a useful research chemical.<br></p>

<p>Applications A hydroxy derivative of dibenzothiophene. Coal model compound used in chemical coal cleaning studies with molten hydroxides.<br>References Nowak, M.A. et al.: Coal Prep., 7, 29 (1989); Nishioka, M. et al.: Anal. Chem., 57, 1327 (1985);<br></p>

<p>Applications (2S,3R,4E)-3-Benzoyl-2-tert-butyloxycarbonylamino-4-octadecen-1,3-diol (cas# 299172-59-1) is a compound useful in organic synthesis.<br>References Kinjo, Y., et al.: Chem. Biol., 15, 654 (2008),<br></p>

<p>Applications 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is used as a reagent in the synthesis of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.<br>References Ding, C.Z., et al.: Bioorg. Med. Chem. Lett., 20, 7317 (2010)<br></p>

<p>Applications trans-2-(Chloromethyl)cyclohexanemethanol is an impurity of Lurasidone Hydrochloride (L474920), an antipsychotic used for treatment of schizophrenia.<br>References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008)<br></p>

<p>Applications 1-Nonadecanol (cas# 1454-84-8) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications 3-Butyn-1-ol is an unsaturated alcohol that is used as a reagent to synthesize Kainic acid (K135000), a neuroexcitatory and neurotoxic analogue of glutamate that is utilized as a means to selectively lesion neuronal cell bodies. 3-Butyn-1-ol is also an important intermediate to prepare a variety of natural products in food and cosmetic industries.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, J. &amp; Whiting, M.: J. Org. Chem., 68, 6160 (2003); Ben-Ari, Y., et al.: Brain Res., 165, 3362 (1979); Olney, J., et al.: Brain Res., 77, 507 (1974); Yu, X., et al.: Org. Prep. Proc. Int., 38, 467 (2006)<br></p>

<p>Applications 2-Nonyn-1-ol is a Propargyl alcohol (P762550) derivative that is used as a reagent to synthesize Microcarpalide, a microfilament disrupting agent that is weakly cytotoxic to mammalian cells. 2-Nonyn-1-ol is also thought to have potential antifungal properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gershon, H., et al.: J. Pharm. Sci., 73, 1840 (1984); Ratnayake, A., et al.: Org. Lett., 3, 3479 (2001); Tamao, K., et al.: Tetrahedron Lett., 29, 6955 (1988)<br></p>

<p>Applications a volatile hydroxy acid component of particular body odors<br>References Rogge, C., et al.: Biochem., 41, 10141 (2002), Natsch, A., et al.: Chem. Biodiversity, 3, 1 (2006), Liu, G., et al.: Biomacromol., 9, 949 (2008),<br></p>

<p>Applications 2,3-Dimethoxyphenol (cas# 5150-42-5) is a useful research chemical.<br></p>

<p>Applications 1-Adamantanemethanol is used as a reagent in the synthesis of adamantane and noradamantane based histone deacetylase (HDAC) inhibitors for the treatment of cancer. It is also used as a reagent in the synthesis of (1-adamantyl)methyl glycidyl ether, a versatile building block for living polymerization.<br>References Gopalan, B., et al.: Bioorg. Med. Chem. Lett., 23, 2532 (2013); Suzuki, T., et al.: J. Med. Chem., 55, 9562 (2012); Moers, C., et al.: Macromol. Rapid Comm., 35, 1075 (2014)<br></p>

<p>Applications m-Xylene-2,4,6-triol is a reagent used to synthesize a series of flavanone derivatives that show anti-tumor activities.<br>References Shi, L., et al.: Biorgan. Med. Chem. Lett., 20, 5466 (2010)<br></p>

<p>Applications 3-(2-Pyridyl)-2-propen-1-ol (cas# 131610-03-2) is a useful research chemical.<br></p>

<p>Applications 3,5-Dimethoxybenzyl Alcohol is used in the synthesis of Resveratrol (R150000).<br></p>

<p>Applications Di-sec-butylphenol, mixture of isomers, predom. 2,6-isomer (cas# 5510-99-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Dimerizes Readily - Store Under Inert Atmosphere<br>Applications 4-Mercaptobenzyl Alcohol, 90% (cas# 53339-53-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Penten-2-ol is used in QSAR studies pertaining to toxicity levels of organic compounds in environmental situations.<br>References Bearden, A.P. et al.: Env. Toxicol. Chem., 16, 1311 (1997);<br></p>

<p>Applications 1-(2H-1,3-benzodioxol-5-yl)prop-2-en-1-ol (cas# 5208-87-7) is a useful research chemical.<br></p>

<p>Applications (S)​-​(-​)​-​1-​Phenyl-​1-​propanol is a building block used in the synthesis of inhibitors of steroid 11-β hydroxylation in the adrenal cortex related to androgen production in the fetus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zolle, I. et al.: J. med. Chem., 51, 2244 (2008);<br></p>

<p>Applications Used in the antileishmanial activity of lipidic amino alcohols.<br>References Coimbra, E.: Chem. Biol. Drug Des. 75, 233 (2010).<br></p>

<p>Applications 23-Azido-3,6,9,12,15,18,21-Heptaoxatricosan-1-ol is used in the synthesis of heterobifunctionalized oligo(ethylene glycol) linkers for use in drug delivery.<br>References Goswami, L. et al.: Org. Biomol. Chem., 11, 1116 (2013);<br></p>

<p>Applications 1-Adamantanebutan-4-ol is a building block used in various synthetic preparations. Adamantanealkanamines are potential antidepressant and anti-Parkinson agents.<br>References Chakrabarti, J., et al.: J. Med. Chem., 17, 602 (1974);<br></p>