Estándares farmacéuticos
Los estándares farmacéuticos son un conjunto integral de materiales de referencia esenciales para garantizar la seguridad, eficacia y calidad de los productos farmacéuticos. Esta categoría incluye estándares para ingredientes farmacéuticos activos (APIs), que son los componentes centrales responsables de los efectos terapéuticos. Además, abarca compuestos y metabolitos relevantes tanto para las industrias farmacéutica como veterinaria, proporcionando puntos de referencia para la medición y análisis precisos de estas sustancias. Los estándares de control de nitrosaminas son cruciales para detectar y mitigar las nitrosaminas potencialmente dañinas en las formulaciones de medicamentos. Los estándares de toxicología ayudan a evaluar la seguridad y los posibles efectos adversos de los compuestos farmacéuticos. Además, los estándares de activadores e inhibidores enzimáticos son vitales para la investigación y el desarrollo, permitiendo estudios precisos de las vías bioquímicas y los mecanismos de acción de los medicamentos. Estos estándares farmacéuticos son herramientas indispensables para el cumplimiento normativo, el control de calidad y la investigación, asegurando que los productos farmacéuticos cumplan con estrictos criterios de seguridad y eficacia.
Subcategorías de "Estándares farmacéuticos"
- APIs para investigación e impurezas(275.014 productos)
- Activadores e inhibidores de enzimas(2.827 productos)
- Nitrosaminas(2.605 productos)
- Compuestos y metabolitos farmacéuticos y veterinarios(2.884 productos)
- Toxicología(13.652 productos)
Se han encontrado 7836 productos de "Estándares farmacéuticos"
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Stigmasta-3,5-diene
CAS:<p>Applications Stigmasta-3,5-diene is one of the components found in vegetable oil after refining.<br>References Lanzon, A., et al.: J. Am. Oil Chemist Soc., 71, 285 (1994); Cert, A., et al.: Food Chem., 49, 287 (1994)<br></p>Fórmula:C29H48·C28H46Forma y color:NeatPeso molecular:779.36(3’S)-ent-Ezetimibe
CAS:<p>Applications An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and cholesterol absorption inhibitor.<br></p>Fórmula:C24H21F2NO3Forma y color:WhitePeso molecular:409.43Ganirelix Trifluoroacetic Acid Salt (>90%)
CAS:Producto controlado<p>Applications Decapeptide LH-RH antagonist. Used in treatment of infertility.<br>References Strickley, R.G., et al.: Pharm. Res., 7, 530 (1990), Jung, G., et al.: J. Med. Chem., 35, 3942 (1992), Rabinovici, J., et al.: J. Clin. Endocrinol. Metab., 75, 1220 (1992), Devroey, P., et al.: Hum. Reprod., 13, 3023 (1998),<br></p>Fórmula:C80H113ClN18O13•x(C2HF3O2)Pureza:>90%Forma y color:NeatPeso molecular:1570.321140221-Carboxylic Acid Triamcinolone Acetonide
CAS:<p>Applications A metabolite of Triamcinolone acetonide.<br>References Edsbacker, S., et al.: Drug Metab. Dispos., 11, 590 (1983), Szefler, S., et al.: Eur. J. Clin. Pharmacol., 30, 323 (1986), Hansel, T., et al.: J. Immunol. Methods, 145, 105 (1991), Argenti, D., et al.: J. Clin. Pharmacol., 39, 695 (1999),<br></p>Fórmula:C24H29FO7Forma y color:NeatPeso molecular:448.48Hydroflumethiazide
CAS:Producto controlado<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Fórmula:C8H8F3N3O4S2Forma y color:NeatPeso molecular:331.29(+)-Citronellal
CAS:Producto controlado<p>Applications (+)-Citronellal is a monoterpene compound that is formed by the metabolism of plants. (+)-Citronellal is a natural insect repellant, and is the main component of citronellal oil. (+)-Citronellal is also used as a starting material in the one pot synthesis of (-)-Menthol (M218875).<br>References Kwon, Y., et al.: Curr. Biol., 20, 1672 (2010); Lenardão, E., et al.: Tetrahedron, 63, 6671 (2007); Milone, C., et al.: Appl. Catal. A-Gen., 199, 239 (2000)<br></p>Fórmula:C10H18OPureza:>90%Forma y color:NeatPeso molecular:154.252-Naphthylamine-d7
CAS:Producto controlado<p>Applications It is listed as a known human carcinogen. Used in manufacturing of dyes, as antioxidant in rubber.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References IARC Monographs, 4, 97 (1974),<br></p>Fórmula:C102H7H2NForma y color:NeatPeso molecular:150.23Glycochenodeoxycholic Acid 3-Sulfate Disodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.<br>References Parmentier, G. , et al.: Steroids, 30, 583 (1977), Tserng, K.Y., et al.: Lipids, 13, 479 (1978),<br></p>Fórmula:C26H41NNa2O8SForma y color:White To Off-WhitePeso molecular:573.65Troglitazone Sulfate Ammonium Salt
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Troglitazone Sulfate is the major metabolite of Troglitazone (T892500), a hypoglycemic agent with cholestatic effect.<br>References Ciaraldi, T.P., et al.: Metabolism, 39, 1056 (1990); Kuzuya, T., et al.: Diabetes Res. Clin. Pract., 11, 147 (1991); Kellerer, M., et al.: Diabetes, 43, 447 (1994); Adachi, Y., et al.: Mol. Pharmacol., 67, 923 (2005);<br></p>Fórmula:C24H30N2O8S2Forma y color:NeatPeso molecular:538.634’-Hydroxyphenprocoumon
CAS:Producto controlado<p>Applications 4’-Hydroxyphenprocoumon is a metabolite of the oral anticoagulant Phenprocoumon (P318820).<br>References De Vries, J. et al.: J. Chrom. Biomed. Appl., 529, 479 (1990);<br></p>Fórmula:C18H16O4Forma y color:NeatPeso molecular:296.32Demethyl Benzydamine Hydrochloride
CAS:Producto controlado<p>Applications A metabolite of Benzydamine (B209950).<br>References Kataoka, S., et al.: Chem. Pharma. Bull., 21, 358 (1973),<br></p>Fórmula:C18H22ClN3OForma y color:Off White SolidPeso molecular:331.842'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is a transformation product of Valsartan (V095750); a nonpeptide angiotensin II AT1-receptor antagonist and antihypertensive. 2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carboxylic Acid is also referred to as Valsartan acid.<br>References Noedler, K., et al.: Water Res., 47, 6650 (2013); Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C14H10N4O2Forma y color:White To Off-WhitePeso molecular:266.25Ouabain-d3 (Major)
CAS:Producto controlado<p>Applications Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);<br></p>Fórmula:C29H41D3O12Forma y color:White To Off-WhitePeso molecular:587.675-Formyltetrahydropteroic Acid
CAS:Producto controlado<p>Impurity Calcium Folinate Hydrate EP Impurity E<br>Stability Unstable in Basic Solution<br>Applications 5-Formyltetrahydropteroic Acid is an impurity of Folic Acid (F680300); a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA. It also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010); Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010); Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010); McKay, D., et al.: Nut. J., 9 (2010)<br></p>Fórmula:C15H16N6O4Forma y color:NeatPeso molecular:344.336-Hydroxy Bromantane
CAS:Producto controlado<p>Applications 6-Hydroxy Bromantane is a metabolite of Bromantane (B678450).<br>References Bi, H., et al.: J. Steroid Biochem. Mol. Biol., 42, 229 (1992), Pozo, O., et al.: Anal. Bioanal. Chem., 389, 1209 (2007), Kiousi, P., et al.: Bioanalysis, 1, 1209 (2009),<br></p>Fórmula:C16H20BrNOForma y color:NeatPeso molecular:322.24Mycophenolic Acid Phenolic β-D-Glucoside
CAS:Producto controladoFórmula:C23H30O11Forma y color:White To Off-WhitePeso molecular:482.48Dipropofol
CAS:<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>Fórmula:C24H34O2Forma y color:NeatPeso molecular:354.532',7'-Difluorofluorescein
CAS:Producto controlado<p>Applications 2',7'-Difluorofluorescein is a reactant used in the synthesis of biarsenical probes that inhibit protein tyrosine phosphatases.<br>References Pomorski, A., et. al.: Org. Biomol. Chem., 13, 1395 (2015)<br></p>Fórmula:C20H10F2O5Forma y color:NeatPeso molecular:368.287Amlodipine Dimethyl Ester
CAS:<p>Impurity Amlodipine EP Impurity F / Amlodipine USP Related Compound F<br>Applications Amlodipine Besilate (A633500) impurity. Amlodipine EP Impurity F<br>References Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007),<br></p>Fórmula:C19H23ClN2O5Forma y color:Light Yellow To YellowPeso molecular:394.85Methyl Lithocholate
CAS:Producto controlado<p>Applications Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.<br>References Roleira, F.M., et al.: Lett. Drug. Design. Discovery., 7, 610 (2010);<br></p>Fórmula:C25H42O3Forma y color:NeatPeso molecular:390.60Des-4-fluorobenzyl Mosapride
CAS:Producto controlado<p>Applications The major metabolite of Mosapride (M731000).<br>References Somogyi, A., et al.: Clin. Pharmacokinet., 8, 463 (1983), Cashman, J., et al.: Drug Metab. Dispos., 21, 587 (1993), Berkman, C., et al.: Biochem. Pharmacol., 50, 565(1995), Blake, B., et al.: Xenobiotica, 25, 377 (1995),<br></p>Fórmula:C14H20ClN3O3Forma y color:NeatPeso molecular:313.784-Hydroxy Propofol Sulfate Sodium Salt
CAS:<p>Applications 4-Hydroxy Propofol sulfate sodium salt is a derivative of Propofol, a hypnotic intravenous agent that is commonly used as an anasthetic for conscious sedation.<br>References GüLCIN, I., et al.: Chem. Pharm. Bull., 53, 281 (2005); Koshy, G., et al.: Am. J. Gastroenterol., 95, 1476 (2000)<br></p>Fórmula:C12H17NaO5SForma y color:NeatPeso molecular:296.32Ethyl Deoxycholate
CAS:<p>Applications Ethyl Deoxycholate is the ethyl ester of the common bile salt Deoxycholic Acid (D232645), a Cholic Acid (C432600) derivative used as a component in cell lysis buffers.<br>References Tuangtong, R. et al.: Dermatol. Surg., 36, 899 (2010); Araki, Y. et al.: Scand. J. Gast., 36, 533 (2001);<br></p>Fórmula:C26H44O4Forma y color:White To Off-WhitePeso molecular:420.63Des[5-(2-dimethylamino)ethyl] Diltiazem
CAS:Producto controlado<p>Applications Diltiazem (D460620) intermediate (impurity B).<br>References Chaffman, M., et al.: Drugs, 29, 387 (1985), Kamath, B., et al.: J. Pharm. Biomed. Anal., 11, 407 (1993), Chankvetadze, B., et al.: J. Pharm. Biomed. Anal., 27, 161 (2002),<br></p>Fórmula:C18H17NO4SForma y color:NeatPeso molecular:343.40O-Methyl Atorvastatin Calcium Salt
CAS:Producto controlado<p>Impurity Atorvastatin EP Impurity G<br>Applications Atorvastatin derivative.<br></p>Fórmula:C34H36FN2O5·CaForma y color:Off-WhitePeso molecular:1183.39Rosuvastatin tert-Butyl Ester
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),<br></p>Fórmula:C26H36FN3O6SForma y color:NeatPeso molecular:537.64Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H22N4O3Forma y color:NeatPeso molecular:330.38Ramiprilat(Mixture of Diastereoisomers)
CAS:Producto controladoFórmula:C21H28N2O5Forma y color:NeatPeso molecular:388.46Diacetyl 2,4-Dinitrophenylhydrazone
CAS:<p>Applications: 2,4-Dinitrophenylhydrazone (DNPH) derivative. Also, it is used in TLC as internal standards.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Fórmula:C10H10N4O5Forma y color:NeatPeso molecular:266.21Ambrisentan
CAS:Producto controlado<p>Applications Nonpeptide endothelin ETA receptor antagonist. Antihypertensive.<br>References Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003),<br></p>Fórmula:C22H22N2O4Forma y color:Off-WhitePeso molecular:378.425α-Pregnane-3β,20(S)-diol
CAS:Producto controlado<p>Applications 5α-Pregnane-3β,20(S)-diol, is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Fórmula:C21H36O2Forma y color:NeatPeso molecular:320.51N-Acetylthiourea
CAS:Producto controlado<p>Applications N-Acetylthiourea is a derivative of Thiourea (T375450); a compound used in biochemistry to increase the solubility (and resolution) of membrane proteins in two-dimensional electrophoresis. N-Acetylthiourea can be used as a reducing agent in a two-part self curing endodontic sealing system.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabbour, S.: Am. J. Clin. Dermatol., 4, 315 (2003); Himsworth, H.: Lancet, 242, 465 (1943); Rabilloud, T., et al.: Electrophoresis, 19, 758 (1998); Jin, S. et al. Self-curing system for endodontic sealant applications. PCT Int. Appl. WO 2009018464 A2 20090205. Feb 5, 2009<br></p>Fórmula:C3H6N2OSForma y color:NeatPeso molecular:118.16Ethyl Cinnamate
CAS:<p>Applications Ethyl Cinnamate, is used in the preparation of polymer-encapsulated osmonium used as a catalyst for the dihydroxylation of alkenes and preparation of a camptothecin intermediate, anticancer drug. Also used in the synthesis of substrate specific ERK1/2 inhibitors used to induce apoptosis and inhibit cell proliferation.<br>References Akiyama, R. et al.: RSC Adv., 2, 7456 (2012); Li, Q. et al.: Bioorg. Med. Chem. Lett., 19, 6042 (2009);<br></p>Fórmula:C11H12O2Forma y color:Colourless To YellowPeso molecular:176.21Bivalirudin α-ASPA 9 Analog Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Fórmula:C98H137N23O34•xC2HF3O2Forma y color:NeatPeso molecular:2181.271α-(Chloromethyl) Chlormadinone Acetate
CAS:Producto controlado<p>(1α)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)-pregna-4,6-<br>diene-3,20-dione; 6-Chloro-1α-(chloromethyl)-17-<br>hydroxypregna-4,6-diene-3,20-dione Acetate; Cyproterone<br>Acetate EP Impurity C</p>Fórmula:C24H30Cl2O4Forma y color:NeatPeso molecular:453.40Muraglitazar
CAS:Producto controlado<p>Applications It is a peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist.<br>References Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 6, 427 (2005), Devasthale, P.V., et al.: J. Med. Chem., 48, 2248 (2005), Kendall, D.M., et al.: Diabetes care, 29, 1016 (2006),<br></p>Fórmula:C29H28N2O7Forma y color:NeatPeso molecular:516.54γ-Butyrobetaine-d9
CAS:Producto controlado<p>Applications γ-Butyrobetaine-d9 is the labelled analogue of γ-Butyrobetaine, a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).<br>References Enomoto, A. et al.: J. Biol. Chem., 277, 36262 (2002)<br></p>Fórmula:C72H9H7NO2Forma y color:NeatPeso molecular:155.26Nilotinib Monohydrochloride Monohydrate
CAS:Producto controladoFórmula:C28H22F3N7O·ClH·H2OForma y color:NeatPeso molecular:583.996,7,8,9-Tetrahydro Carvedilol
CAS:Producto controlado<p>Applications Carvedilol (C184625) derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C24H30N2O4Forma y color:NeatPeso molecular:410.514-Hydroxy Estrone 1-N7-Guanine
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H25N5O4Forma y color:NeatPeso molecular:435.48CRL-40,941
CAS:Producto controlado<p>Applications CRL-40,941 is a wakefulness-promoting agent. It was found to produce antiaggressive effects in animals.<br>References Lafon, L.: US4489095 (A) (1984)<br></p>Fórmula:C15H13F2NO3SForma y color:WhitePeso molecular:325.332-(1-Hydroxyethyl) Promazine
CAS:<p>Applications A metabolite of Acepromazine (A130900).<br>References Cossum, P., et al.: Drug Dispos., 9, 321 (1988), Stowell, L., et al.: J. Anal. Toxicol., 22, 166 (1998),<br></p>Fórmula:C19H24N2OSForma y color:NeatPeso molecular:328.47rac 1-Methoxy Ketorolac
CAS:Producto controlado<p>Applications An impurity of the analgesic Ketorolac (K235650).<br></p>Fórmula:C16H15NO4Forma y color:NeatPeso molecular:285.29Imipenem, Monohydrate
CAS:Producto controladoFórmula:C12H17N3O4S·H2OForma y color:White To Light YellowPeso molecular:317.366-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt
CAS:<p>Applications 6-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt is used the in the synthesis of azo dyes and pigments.<br>References Gao, Pu. et al., Dyes Pigm. 179, 108376(2020);<br></p>Fórmula:C10H7O4S·KForma y color:NeatPeso molecular:262.3235Diazoxide-d3
CAS:Producto controlado<p>Applications Diazoxide-d3 is the labeled analogue of Diazoxide (D417305), which reduces status epilepticus neuron damage in diabetes.<br>References Baba, A., et al.: J. Neurosci., 23, 7737 (2003); Bancila, V., et al.: J. Neurochem., 90, 1243 (2004); Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005)<br></p>Fórmula:C8H4D3ClN2O2SForma y color:NeatPeso molecular:233.699α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
CAS:<p>Impurity Clobetasol Propionate EP Impurity J<br>Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Fórmula:C25H30ClFO4Forma y color:NeatPeso molecular:448.957α-Thiomethyl Spironolactone-d7 (Major)
CAS:Producto controlado<p>Applications A labelled metabolite of Spironolactone.<br>References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),<br></p>Fórmula:C23H25D7O3SForma y color:NeatPeso molecular:395.61Camphorquinone-10-sulfonic Acid Hydrate
CAS:Producto controlado<p>Applications A crystalline water-soluble reagent that is useful for specific, reversible modification of the guanidino groups of arginine residues. Suitable for use with small arginine-containing molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wallace, C.J.A., et al.: Biochem. J., 215, 651 (1983), Dailey, H.A., et al.: J. Biol. Chem., 261, 7902 (1986),<br></p>Fórmula:C10H14O5S·H2OForma y color:NeatPeso molecular:264.30Etomidate Hydrochloride
CAS:Producto controlado<p>Applications (cas# 53188-20-8) is a useful research chemical.<br></p>Fórmula:C14H17ClN2O2Forma y color:NeatPeso molecular:280.75rac-syn N,N-Diethyl Norephedrine
CAS:Producto controlado<p>Applications The main basic metabolite of Diethylpropione.<br>References Banci, F., et al.: Arzneim.-Forsch., 21, 1616 (1971), Mikhailova, D., et al.: Eur. J. Med. Chem., 13, 49 (1978),<br></p>Fórmula:C13H21NOForma y color:NeatPeso molecular:207.31Betamethasone 6α-Bromo 17-Valerate
Producto controlado<p>Applications Betamethasone 6α-Bromo 17-Valerate is an impurity of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Fórmula:C27H36BrFO6Forma y color:NeatPeso molecular:555.47Allo-3α-tetrahydro Cortisol
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Cortisol (H714615).<br>References Quinkler, M., et al.: J. Clin. Endocrinol. Metab., 88, 2384 (2003), Draper, N., et al.: J. Endocrinol., 186, 251 (2005), Kotlowska, A., et al.: Clin. Biochem., 42, 448 (2009),<br></p>Fórmula:C21H34O5Forma y color:Off White SolidPeso molecular:366.49Chenodeoxycholic acid-3-β-D-glucuronide
CAS:Producto controladoFórmula:C30H48O10Forma y color:White To Off-WhitePeso molecular:568.7Bromantane
CAS:Producto controlado<p>Applications Bromantane is an adamantane derivative used as an anxiolytic agent.<br>References Reznikov, A., et al.: Endokrinologie, 73, 11 (1979), Grekhova, T., et al.: Bull. Eksp. Biol. Med., 119, 302 (1995),<br></p>Fórmula:C16H20BrNForma y color:White To Off-WhitePeso molecular:306.24Dimethyl 2,7-Naphthalenedicarboxylate
CAS:Producto controlado<p>Applications Dimethyl 2,7-Naphthalenedicarboxylate (cas# 2549-47-5) is a useful research chemical.<br></p>Fórmula:C14H12O4Forma y color:Off White To Light YellowPeso molecular:244.243Zolpidem Phenyl-4-carboxylic Acid
CAS:<p>Applications A major metabolite of Zolpidem.<br>References Crestani, F., et al.: Br. J. Pharmacol., 131, 1251 (2000), Li, Q., et al.: Bioorg. Med. Chem. Lett., 12, 465 (2002), Goulle, J., et al.: Ther. Drug Monit., 26, 206 (2004), Ohkanda, J., et al.: J. Med. Chem., 47, 432 (2004), Blackaby, W., et al.: Bioorg. Med. Chem. Lett., 16, 1175 (2006),<br></p>Fórmula:C19H19N3O3Forma y color:Off-White To Light BeigePeso molecular:337.37Piretanide
CAS:<p>Applications High-ceiling loop diuretic; structurally related to Bumetanide (B689550). Diuretic.<br>References Merkel, W., et al.: Eur. J. Med. Chem., 11, 399 (1976), Pozet, N., et al.: Br. J. Clin. Pharmacol., 9, 577 (1980), Clissold, S.P., et al.: Drugs, 29, 489 (1985),<br></p>Fórmula:C17H18N2O5SForma y color:Light Yellow SolidPeso molecular:362.40Desacetyl Diltiazem
CAS:<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Fórmula:C20H24N2O3SForma y color:White To BrownPeso molecular:372.48Petromyzonol 24-Sulfate Sodium Salt
CAS:Producto controladoFórmula:C24H41O7S·NaForma y color:NeatPeso molecular:496.63Benoxaprofen
CAS:Producto controlado<p>Applications A non-steroidal anti-inflammatory ophthalmic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mathur, K., et al.: Bioorg. Med. Chem., 11, 1915 (2003), Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007), Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009),<br></p>Fórmula:C16H12ClNO3Forma y color:NeatPeso molecular:301.72Melagatran
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Synthetic thrombin inhibitor. Thrombin mutant anticoagulant antagonist. Antithrombotic.<br>References Dewanjee, M., et al.: J. Nucl. Med., 22, 981 (1981), Goodman, S., et al.: J. Biomed. Mater. Res., 45, 240 (1999), Carlsson, S., et al.: Thromb. Res., 115, 9 (2005),<br></p>Fórmula:C22H31N5O4Forma y color:NeatPeso molecular:429.51trans-α-Asarone
CAS:Producto controladoFórmula:C12H16O3Forma y color:White To Off-WhitePeso molecular:208.25Bromfenac Sodium Sesquihydrate
CAS:Producto controlado<p>Applications Bromfenac is a non-steroidal anti-inflammatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), MacDonald, J., et al.: Toxicol. Sci., 110, 40 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C15H11BrNO3·2Na·3H2OForma y color:Light YellowPeso molecular:766.342,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5
CAS:Producto controlado<p>Applications 2,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5 is the isotope labelled analog of 2,3,4-Trihydroxybenzophenone; a trihydroxy derivative of Benzophenone (B204980) which is a compound used in the manufacturing of antihistamines, hypnotics, and insecticides.<br>References Wallace, W., et al.: Environ. Toxicol. Chem., 19, 962 (2000); Hayashi, T., et al.: Toxicol. Lett., 167, 1 (2006); Bechard, K., et al.: Aquat. Toxicol., 90, 310 (2008)<br></p>Fórmula:C13D5H5O4Forma y color:NeatPeso molecular:235.2477-Bromobenz[a]anthracene
CAS:Producto controlado<p>Applications 7-Bromobenz[a]anthracene (cas# 32795-84-9) is a useful research chemical.<br></p>Fórmula:C18H11BrForma y color:NeatPeso molecular:307.18N1,N12-Diacetylspermine Dihydrochloride
CAS:<p>Stability Hygrscopic<br>Applications N1,N12-Diacetylspermine Dihydrochloride is a diacetylated derivative of Spermine (S680510) and is recognized as a novel tumor marker in patients with breast and colorectal cancers.<br>References Kato, M., et al.: Anticancer Res., 34, 3053 (2014); Umemori, Y., et al.: Clin. Chim. Acta, 411, 1894 (2010); Kawakita, M., et al.: J. Biochem., 139, 315 (2006); Hiramatsu, K., et al.: Clin. Cancer Res., 11, 2986 (2005)<br></p>Fórmula:C14H32Cl2N4O2Forma y color:NeatPeso molecular:359.345-Hydroxy Albuterol Hemisulfate Salt
CAS:Producto controlado<p>Applications The 5-hydroxy analogue of the bronchodilator, Albuterol (A514500).<br></p>Fórmula:C13H21NO4H2SO4Forma y color:NeatPeso molecular:304.35N-Isopropyl Noratropine
CAS:Producto controlado<p>Impurity Ipratropium EP Impurity E<br>Applications N-Isopropyl Noratropine is a Noratropine derivative, an intermediate in the production of Ipratropium.<br>References Simms, P., et al.: J. Pharm. Biomed. Anal., 17, 841 (1998),<br></p>Fórmula:C19H27NO3Forma y color:NeatPeso molecular:317.42Telocinobufogenin
CAS:Producto controlado<p>Applications Telocinobufagin is isolated as a major component from skin secretion of the toad Bufo rubescens. Telocinobufogenin is a novel antibiotic cardiotonic.<br>References Akizawa, T., et al.: Chem. Pharm. Bull., 42, 754 (1994); Hancock, R., et al.: Antimicrob. Agents Chemother., 43, 1317 (1999); Jing, Y., et al.: J. Cancer Res., 85, 645 (1994); Kamano, Y., et al.: J. Med. Chem., 45, 5440 (2002); Schoner, W., et al.: Eur. J. Biochem., 269, 2440 (2002); Cunha Filho, G., et al.: Toxicon, 45, 777 (2005)<br></p>Fórmula:C24H34O5Forma y color:NeatPeso molecular:402.52(-)-Biotin Sulfoxide
CAS:<p>Applications (-)-Biotin Sulfoxide, is a metabolite of Biotin (B389040), which is a growth factor present in minute amounts in every living cell, and plays an indispensable role in numerous naturally occurring carboxylation reactions.<br>References du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992),<br></p>Fórmula:C10H16N2O4SForma y color:White To Off-WhitePeso molecular:260.31Tenivastatin Calcium Hydrate
CAS:Producto controlado<p>Applications Tenivastatin Calcium is derived from Simvastatin (S485000), which is a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor.<br>References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986)<br></p>Fórmula:C25H39O6Ca·xH2OForma y color:NeatPeso molecular:929.24O-Desmethyl Quinidine
CAS:Producto controlado<p>Applications A metabolite of Quinidine.<br>References Small, D.L., et al.: J. Chem. Med., 22, 1014 (1979), Guentert, T.W., et al.: Eur. J. Drug Metab. Pharmacokinet., 7, 31 (1982), Rakhir, A., et al.: J. Pharmacokinet. Biopharm., 12, 1 (1984), Christie, D.J., et al.: J. Lab. Clin. Med., 112, 92 (1988),<br></p>Fórmula:C19H22N2O2Forma y color:NeatPeso molecular:310.39N-Demethyl Mifepristone
CAS:<p>Applications A metabolite of Mifepristone (M343975).<br>References Ringler, I., et al.: Metabolism, 13, 37 (1964), Gagne, D., et al.: J. Steroid. Biochem., 25, 315 (1986), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Hild, S., et al.: Hum. Reprod., 15, 822 (2000), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C28H33NO2Forma y color:NeatPeso molecular:415.5717-Desacetyl Rocuronium Bromide
CAS:<p>Impurity Rocuronium EP Impurity C<br>Applications 17-Desacetyl Rocuronium Bromide (Rocuronium EP Impurity C) is a metabolite of Rocuronium (R639500), in human plasma.<br>References Kleef, U., et al.: J. Chromatogr., 621, 65 (1993), Proost, J., et al.: Br. J. Anaesth., 85, 717 (2000),<br></p>Fórmula:C30H51N2O3·BrForma y color:NeatPeso molecular:567.64(+)-(S)-Dihydrokavain
CAS:Producto controlado<p>Applications (+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.<br>References Warburton, E., et al.: Eur. J. Mass Spectrom., 12, 223(2006); Wang, J., et al.: J. Food Sci. Technol., 52, 1164 (2015)<br></p>Fórmula:C14H16O3Forma y color:NeatPeso molecular:232.28N-Desmethyl Ulipristal Acetate
CAS:Producto controlado<p>Applications N-Desmethyl Ulipristal Acetate is the N-monodemethylated analogue and metabolite of the selective progesterone receptor modulator Ulipristal Acetate (U700810). N-Desmethyl Ulipristal Acetate contributes significantly to the antiprogestational activity of its parent compound.<br>References Attardi, B.J. et al.: J. Steroid Biochem. Mol. Biol., 88, 277 (2004);<br></p>Fórmula:C29H35NO4Forma y color:NeatPeso molecular:461.592-(2,3-Dichlorphenyl)-2-(guanidinylimino)acetonitrile
CAS:Producto controladoFórmula:C9H7Cl2N5Forma y color:Light YellowPeso molecular:256.09b-Cembrenediol
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.<br>References Le-Huu, P. et al.: ChemCatChem., 8, 3755 (2016); Ebrahim, H. et al.: Bioorg. Med. Chem., 24, 5748 (2016);<br></p>Fórmula:C20H34O2Forma y color:Off-WhitePeso molecular:306.483-Sulfoglycolithocholic Acid Disodium Salt
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 3-Sulfoglycolithocholic Acid Disodium Salt is a derivative of Lithocholic acid (L469180). Lithocholic acid (LCA) is a putative tumor promoter,that is shown to be able to inhibit mammalian DNA polymerase β.<br>References Ogawa, A., et al.: Jap. J. Canc. Res., 89, 1154 (1998)<br></p>Fórmula:C26H41NO7S·2NaForma y color:NeatPeso molecular:557.656β-Hydroxy-3α,5α-cycloandrostan-17-one
CAS:Producto controlado<p>Applications 6β-Hydroxy-3α,5α-cycloandrostan-17-one is a degredation product of Dehydroepiandrosterone Sodium Sulfate (S673250), an active agent in the preparation of a pharmaceutical for the treatment of asthma or other respiratory diseases.<br>References Ishihara, T., et al.: Drug. Develop. Indust. Pharmacy., 5, 263 (1979); Sollman, P.B., et al.: J. Org. Chem., 28, 3559 (1963); Van Renterghem, P., et al.: Steroids., 75, 1047 (2010);<br></p>Fórmula:C19H28O2Forma y color:NeatPeso molecular:288.42Adapalene Methyl Ester
CAS:<p>Impurity Adapalene USP Related Compound B<br>Applications Adapalene intermediate, an ester of Adapalene. Adapalene USP Related Compound B.<br>References Charpentier, B., et al.: J. Med. Chem., 38, 4993 (1995),<br></p>Fórmula:C29H30O3Forma y color:NeatPeso molecular:426.55Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt
CAS:Producto controlado<p>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications Fluvastatin 3-Hydroxy-4,6-diene Sodium Salt is a metabolite of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993),<br></p>Fórmula:C24H23FNNaO3Forma y color:NeatPeso molecular:415.43(5α)-Androst-2-en-17-one, 90%
CAS:Producto controlado<p>Applications Metabolite of 5α-Androst-16-en-3β-ol<br>References Gower, D., et al.: J. Steroid Biochem. Mol. Biol., 63, 81 (1997), Zorko, M., et al.: Steroids, 65, 46 (2000), Diel, P., et al.: Toxicol. Lett., 169, 64 (2007),<br></p>Fórmula:C19H28OPureza:90%Forma y color:NeatPeso molecular:272.422-Butylnaphthalene
CAS:Producto controlado<p>Applications 2-BUTYLNAPHTHALENE (cas# 1134-62-9) is a useful research chemical.<br></p>Fórmula:C14H16Forma y color:NeatPeso molecular:184.277Beclomethasone 21-Propionate
CAS:Producto controlado<p>Impurity Beclomethasone Dipropionate EP Impurity A<br>Applications Beclomethasone 21-Propionate (Beclomethasone Dipropionate EP Impurity A) is a metabolite of Beclomethasone Dipropionate (BDP).<br>References Foe, K., et al.: Biopharm. Drug Disposition, 19, 1 (1998), Harrison, L., et al.: Eur. J. Clin. Pharmacol., 58, 197 (2002),<br></p>Fórmula:C25H33ClO6Forma y color:WhitePeso molecular:464.98Carvedilol Bis-carbazole
CAS:Producto controlado<p>Impurity Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B<br>Applications Carvedilol Bis-carbazole (Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B) is an impurity from the process of Carvedilol (C184625).<br></p>Fórmula:C39H39N3O6Forma y color:Off-White To Light BeigePeso molecular:645.74Fluorescein-Cadaverine Dihydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Fluorescein-Cadaverine is a fluorescein derivative used in the preparation of biologically active fluorescent-labeled vitamin K analogues and monitoring of their subcellular distribution.<br>References Suhara, Y. et al.: Tetrahedron, 64, 8789 (2008);<br></p>Fórmula:C26H25N3O5S·2ClHForma y color:Orange SolidPeso molecular:564.48Testosterone Hexanoate
CAS:Producto controladoFórmula:C25H38O3Forma y color:NeatPeso molecular:386.57α-Ethyl Norepinephrine Hydrochloride (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications A bronchodilator.<br>References Daly, J. W., et al.: J. Med. Chem., 9(3), 273 (1966).<br></p>Fórmula:C10H15NO3·ClHForma y color:NeatPeso molecular:233.693”-Hydroxy Simvastatin
CAS:Producto controladoFórmula:C25H38O6Forma y color:NeatPeso molecular:434.57Betamethasone 21-Propionate
CAS:Producto controlado<p>Impurity Clobetasol Propionate EP Impurity K / Betamethasone Dipropionate EP Impurity C<br>Applications Betamethasone 21-Propionate (Clobetasol Propionate EP Impurity K) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C25H33FO6Forma y color:Off-WhitePeso molecular:448.52Vanillin
CAS:<p>Applications The primary component of Vanilla bean extract.<br>References Nazeruddin, G., et al.: Res. J. Pharm., Biol. Chem. Sci., 2, 71 (2011), Yang, X., et al.: Biores. Technol., 102, 3498 (2011),<br></p>Fórmula:C8H8O3Forma y color:NeatPeso molecular:152.15Betamethasone-∆17,20 21-Aldehyde(Mixture of Isomers)
CAS:Producto controlado<p>Applications A degradation and metabolic intermediate of Betamethasone (B3270000).<br></p>Fórmula:C22H27FO4Forma y color:NeatPeso molecular:374.45Hydrocinnamic Acid
CAS:<p>Applications Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.<br>References Migliaccio, A., et al.: Blood, 76, 1150 (1990), McDonagh, K., et al.: J. Biol. Chem., 266, 11965 (1991),<br></p>Fórmula:C9H10O2Forma y color:WhitePeso molecular:150.173(R,S)-Hydroxy Desogestrel
CAS:Producto controlado<p>Applications A metabolite of Desogestrel.<br>References Back, D., et al.: Br. J. Clin. Pharmacol., 26, 23 (1988), Wienkers, L., et al.: Drug Metab. Dispos., 1990, 24, 610 (1990), Bourrie, M., et al.: J. Pharmacol. Exp. Ther., 277, 321 (1996), Ono, S., et al.: Xenobiotica, 26, 681 (1996),<br></p>Fórmula:C22H30O2Forma y color:NeatPeso molecular:326.47Diphenhydramine N-Oxide
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Diphenhydramine (D486900) in humans.<br>References Breyer-Pfaff, U., et al.: Drug Metab. Dispos., 25, 340 (1997),<br></p>Fórmula:C17H21NO2Forma y color:NeatPeso molecular:271.35
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