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Biotinylation reagent for labeling nucleic acids or proteins.

Diazolidinyl urea is a preservative used in cosmetics and pharmaceuticals. It is an antimicrobial agent that causes cell lysis by inhibiting the respiratory synthesis of bacteria. Diazolidinyl urea has been shown to be effective against Gram-positive and Gram-negative bacteria, yeast, and mold. The analytical method for diazolidinyl urea is well established, with detection limits of 0.1 ppm. Diazolidinyl urea is stable under normal conditions, but can be degraded by heat or pH changes. This preservative also inhibits microbial growth by reducing the availability of p-hydroxybenzoic acid (pHBA) and formaldehyde as substrates for bacterial metabolism. Diazolidinyl urea also prevents the formation of biofilms on wet surfaces and exhibits some anti-inflammatory effects.

5,6,7,8-Tetrahydro-[1,8]naphthyridine-2-carboxylic acid is a chemical compound with CAS No. 885278-22-8. It is a high quality reagent that can be used as a building block for the synthesis of complex compounds. 5,6,7,8-Tetrahydro-[1,8]naphthyridine-2-carboxylic acid can also be used as a reaction component in chemical synthesis and as an intermediate in the production of various fine chemicals and speciality chemicals.

2,6-Dichlorocinnamic acid is an organic compound that is used as a reagent in the synthesis of other chemicals. 2,6-Dichlorocinnamic acid has been used as a component in the synthesis of various kinds of fine chemicals and useful building blocks. This chemical is also used as a speciality chemical and research chemical. 2,6-Dichlorocinnamic acid can be used as a versatile building block for the preparation of various compounds. It can be synthesized by heating cinnamic acid with chlorine gas and then reacting it with sodium hydroxide.

Sodium nitroprusside dihydrate is an oxygen transport agent that works by inhibiting the enzyme cyclase. This inhibits the production of tnf-α and other inflammatory mediators, which reduces inflammation and pain. Sodium nitroprusside dihydrate is used to lower blood pressure in emergency situations, such as shock. It has been shown to be effective for treating pulmonary hypertension, chronic obstructive pulmonary disease, and other conditions related to oxygen transport. Sodium nitroprusside dihydrate is a metastable molecule that can be converted into a stable form (sodium nitroprusside) by ester hydrochloride or fatty acid esters.

(+)-Biotin-(PEO)3-amine is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. (+)-Biotin-(PEO)3-amine is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

4'-(Trifluoromethyl)acetophenone is a phosphatase inhibitor that has been shown to have inhibitory activity against chemokines. Chemokines are a type of cytokine that are secreted by immune cells and play an important role in inflammation. 4'-(Trifluoromethyl)acetophenone has also been shown to have an effect on the cell membrane permeability of amines and 2-aminobenzyl alcohol, which are substrates for the enzyme. 4'-(Trifluoromethyl)acetophenone reacts with imidazole derivatives, such as trifluoride, forming hydrogen bonds between the two molecules. Kinetic studies have demonstrated that this reaction is reversible in solution at room temperature.

Applications Guanosine-5'-triphosphate disodium salt (CAS# 56001-37-7) is a nucleotide used in the preparation of photoreactive GTP affinity probes, and in inhibitors of eukaryotic initiation factor eIF-4E.
References George Cisar, E. A.; J. Am. Chem. Soc., 135, 4676 (2013); Ghosh, P.; et al.: Bioorg. Med. Chem. Lett., 16, 750 (2006).

Applications N-Acetylethylene Urea-d4 (cas# 1189701-94-7) is a compound useful in organic synthesis.

2'-Fluoro-4'-hydroxyacetophenone is a glycosylated molecule that is used in phase transfer catalysis. It is a glycoside that can undergo the glycosylation reaction and can be used as a phase transfer reagent. 2'-Fluoro-4'-hydroxyacetophenone has been studied for its potential use in the synthesis of xylosides and selenadiazoles. In addition, it has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Dipyrone is an anti-inflammatory and analgesic drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to inhibit the production of prostaglandins, which are involved in inflammation, by inhibiting cyclooxygenase. The polymerase chain reaction (PCR) method is a biochemical technique used to amplify a segment of DNA, typically for use as a genetic marker or for cloning a particular gene. A PCR assay can be used to detect the presence of bacterial DNA in a sample. Dipyrone has been shown to possess chemiluminescence activity, which is indicative of its ability to bind with DNA. This binding inhibits transcription and replication and may be responsible for the toxic effects on epidermal cells observed in animal studies. Dipyrone also has been shown to have anti-inflammatory activities through its inhibition of cyclooxygenase and its ability to inhibit neutrophil migration and function.

1-(Trimethylsilyl)-2-naphthyl Trifluoromethanesulfonate is a solvent that has been used for the synthesis of oxygen heterocycles. It is also used as a reagent to cleave bonds in organic molecules, such as alkene, solvents, aldehydes and activated esters. This compound is an unsymmetrical nucleophile that reacts with electron-poor alkenes to generate an unsaturated bond between two carbons. Mechanistic studies have shown that the reaction proceeds through a concerted mechanism involving the formation of a covalent phosphine intermediate.

Please enquire for more information about 5-Methyl-2-nitropyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

3,3'-Diheptyloxacarbocyanineiodide (DHCI) is a fluorescent probe that is used in the treatment of solid tumours. It is taken up by tumor cells and causes them to fluoresce, which can be seen under a microscope. DHCI has been shown to be effective against hypoxic tumours and tumors with low oxygen levels due to its ability to penetrate tumor cells and deliver oxygen. The uptake of DHCI by cancer cells is also dependent on the permeability of the blood vessels present in the tumor. This drug has been shown to have a large therapeutic window for treatment of solid tumours.

N-a-t-Boc-N-g-trityl-L-asparagine is a recombinant human protein that has been synthesized in E. coli. It is a peptide with 17β-estradiol at its C terminus, and it binds to the oestrogen receptor α (ERα) via hydrogen bonding interactions. The linker between the asparagine and estradiol is a Boc group that can be removed by protease activity, revealing the active form of 17β-estradiol. ERα ligates to N-a-t-Boc-N-g-trityl L asparagine with high affinity, and this interaction is reversible. The linker also contains a functional group for surface attachment, which may be used to attach this peptide to a solid support or tissue culture substrate for use in cell cultures.
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5-Amino-o-cresol is a chemical compound that is used in analytical chemistry as an aminophenol. It reacts with ethylene diamine to form a red dye called 5-aminonaphthalene-2,7-disulphonic acid (5ANDS). The reaction solution can be used to identify the presence of bacterial DNA. 5-Amino-o-cresol has been shown to have genotoxic effects, which may lead to skin cancer or skin damage. This chemical also has toxicological properties and can cause skin irritation at high concentrations.