Glycoscience

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>3, 4-Dihydroxy-5-(hydroxymethyl)pyrrolidinone (3R,4R,5S) is a custom synthesis of a fluorinated compound that has been modified through methylation and monosaccharide substitution. This product has been designed for use in Click chemistry applications. The CAS number for this product is 100906-64-6.</p>

<p>GQ1b ganglioside (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with two sialic acids (NeuAc) linked α2,3/α2,8 to the inner galactose residue, two sialic acids (NeuAc) linked α2,3/α2,8 to the terminal galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Anti-GQ1b ganglioside antibody is associated with Miller Fisher syndrome and is also found in patients with related conditions that may share the same pathogenic mechanism, such as, Bickerstaff brainstem encephalitis. Thus, the measurement of the anti-GQ1b antibody in suspected cases of Miller Fisher syndrome is a useful diagnostic marker (Paparounas, 2004). It has been found that GQ1b ganglioside contributes to synaptic transmission and synapse formation. Low concentrations of GQ1b ganglioside, evoked dopamine (DA) release from laboratory tissues (Chen, 2018).</p>

<p>Pullulan is a glucan elaborated by the fungus Aureobasidium pullulans. The chemical structure is essentially repeating units of maltotriose joined by α-1,6 linkages. Pullulan dissolves readily in water to form stable, viscous solutions that do not gel. The polysaccharide can be moulded, made into fibres and forms clear soluble films. Applications are in foods as a low calorie ingredient and the polysaccharide forms water soluble films that have been used as seed coatings and to coat fruit. Pullulan can also be used in industrial applications as a binder, film former and in pharmaceutical applications.  Average MW is typically 100-200kDa.  Viscosity is ca 120 mm2/s.<br>The image was kindly provided by Dr. Chris Lawson.</p>

<p>B-D-glucose is a monosaccharide with the molecular formula C6H12O6. It is the major form of glucose in plants, and is one of the simplest carbohydrates. B-D-glucose is synthesized by photosynthesis in plants and used as an energy source for cellular respiration. The hydroxyl group of b-D-glucose reacts with p-hydroxybenzoic acid to form a new compound called glucopyranosiduronic acid. The hydroxyl group also reacts with sodium citrate to form sodium hydrogen citrate. This reaction can be used to measure the concentration of b-D-glucose in an unknown solution using high performance liquid chromatography (HPLC). B-D-glucose has been shown to have antidiabetic activity, as it improves insulin sensitivity, reduces blood glucose levels, and decrease body mass index (BMI) in animal models. A model system</p>

a-D-Galactosamine-1-phosphate is a synthetic, fluorinated glycosylation inhibitor. It inhibits the synthesis of complex carbohydrates and is used in biochemical research. This compound has been shown to inhibit the methylation of glycoproteins and polysaccharides. It also inhibits the phosphorylation of glycogen, which may be useful in cases of diabetes mellitus.

Robinose is a flavonoid derivative that is used as a conditioning agent in animal health products. It has been shown to increase the efficacy of an antigen by enhancing the immune response. Robinose also has enzyme activities and has been shown to work synergistically with other flavonoids such as quercetin. In addition, it can be used as an analytical method for glycan structures. Robinose is typically produced from the hydrolysis of flavonol glycosides found in plants such as raspberries, blackberries, and blueberries. It can also be extracted from sugar beet molasses or sugar cane molasses.

<p>Versatile resource for organic synthesis, e.g. of the inhibitor swainsonine</p>

(3R, 5R) -1-Benzyl-3, 4, 5- piperidinetriol is a modification of the parent compound. The modification of the parent compound is accomplished by the introduction of a benzyl group at the 3' and 5' positions of the molecule. This modification can be used to synthesize oligosaccharides, which are complex carbohydrates. (3R, 5R) -1-Benzyl-3, 4, 5- piperidinetriol is synthesized from high purity (99%) monosaccharide methylated with formaldehyde in aqueous solution with hydrochloric acid and sodium hydroxide as catalysts. It has CAS number 8056-97-2 and molecular weight of 231.24 grams per mole.

Bisbiguanide antiseptic and disinfectant used in topical antibacterial products

<p>Allyl 2,3,4-tri-O-benzyl-a-D-glucopyranoside is a sugar that is used in the synthesis of glycosides. It can be synthesized by a click modification reaction that yields an allyl ether from an allylic alcohol. This product has been shown to react with bromine in the presence of UV light and produce a monobenzylated product, which can be used as a fluorescent probe for labeling saccharides. Allyl 2,3,4-tri-O-benzyl-a-D-glucopyranoside can also be modified with methyl groups or glycosidic bonds to form complex carbohydrates.</p>

2-Acetamido-1,3,4,6-tetra-O-benzyl-2-deoxy-a-D-glucopyranoside is a modification of the natural carbohydrate. It is an oligosaccharide synthesized with custom synthesis. The synthetic process involves the methylation and glycosylation of the monosaccharides. Fluorination and saccharide linkages are also used in the production of this compound. 2-Acetamido-1,3,4,6-tetra-O-benzyl-2-deoxyglucopyranoside can be used as a building block for complex carbohydrates or as a research reagent for glycobiology.

<p>1,2,3,4-Tetra-O-benzyl-a-D-mannopyranoside is an active drug that belongs to the group of thyromimetics. It is a prodrug that is hydrolyzed in vivo to 1,2,3,4-tetra-O-acetyl-a-D-mannopyranose. This drug has been shown to be effective in treating nervous system diseases such as sclerosis and endogenous disease. The acetylation of the benzyl group on this molecule prevents it from being metabolized by enzymes that are found in the liver. The unmodified form of this drug is rapidly absorbed into the blood and reaches high concentrations quickly.</p>

This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

a-D-[UL-13C6]Glucose-1-phosphate dipotassium salt hydrate is a kinetic and structural analysis of the glucose phosphate metabolic pathway. It has been used to study biochemical properties of the glucose phosphate metabolic pathway, and to study the control mechanisms for this process. Specifically, it has been used to determine kinetic parameters that are necessary for understanding glucose metabolism. This compound has also been used to study hydrogen bonding interactions between monoclonal antibodies and ganoderma lucidum and transfer reactions of immobilized enzymes. The pH optimum for this compound is 4.5, and it can be synthesized from solanum tuberosum.

<p>(1S) -1- [(2S, 3R) - 3- Hydroxy- 1- ((4-methoxyphenyl)methyl) - 2- azetidinyl] -1, 2- ethanediol is a synthetic monosaccharide. It can be used in the synthesis of oligosaccharides and glycosylations. Click modification, methylation, and fluorination are all possible modifications for this product. The CAS number for this item is 52634-73-0.</p>

<p>1,2:4,5-Di-O-cyclohexylidene-b-D-fructopyranose is a modification of the natural carbohydrate 1,2:4,5-di-O-isopropylidene-b-D-fructopyranose. It is an oligosaccharide composed of three units of b-D-fructofuranose linked by α-(1,2) and β-(1,4) glycosidic bonds. The methylation and glycosylation of this saccharide can be customized to produce a wide range of products with different properties. 1,2:4,5 Di O cyclohexylidene b D fructopyranose can be used in applications such as pharmaceuticals and agrochemicals.<br>The molecular formula for this compound is C10H14O8 and its CAS number is 18608-92-9.</p>

1,3:1,4-B-Glucotriose (B) is a carbohydrate that is a monosaccharide. It is also an oligosaccharide that is classified as a complex carbohydrate. This compound can be synthesized with high purity and custom synthesis. 1,3:1,4-B-Glucotriose (B) can be modified with fluorination, methylation, glycosylation, and click modification. This product has CAS No. 157544-59-7.

1-Deoxy-3,4-O-isopropylidene-L-tagatose is a synthetic sugar that is modified by the addition of a fluorine atom at the 1 position. This modification prevents the enzyme glycosidase from cleaving this sugar and releasing glucose. 1DILT can be used to produce glycans with different structures, including complex carbohydrates. The CAS number for this product is 7062-93-5.

<p>This is a custom synthesis of 5-azido-5-deoxy-2,3-O-isopropylidene-2-[(trifluoromethanesulfonyloxy)methyl]-D-ribono-1.4 -lactone (5ADL). The compound can be used as a synthetic intermediate and is a glycoside that contains an azido group. It is also known as a sugar and has the CAS number: 6374506-32-8. This compound has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis, DNA replication, and RNA transcription.</p>

<p>3-O-(2-Acetamido-2-deoxy-a-D-galactopyranosyl)-D-galactopyranose is an endothelial cell growth factor that is generated by the enzymatic activity of galactosyltransferase. It binds to lectin, glycan, and monoclonal antibodies. This molecule has been shown to have biological properties that are related to cancer and immunology. 3-O-(2-Acetamido-2-deoxy-a-D-galactopyranosyl)-D-galactopyranose may be used as a glycolipid marker in blood group typing and in the detection of cervical cancer cells.</p>

<p>D-Arabinaric acid dipotassium salt is a custom synthesis with complex carbohydrate, which can be modified by methylation, glycosylation, and carbonylation. It has CAS number 6703-05-5 and a high purity. This product is also fluorinated, which makes it an excellent synthetic reagent.</p>

<p>Phenyl 3-O-Allyl-2,4,6-tri-O-benzyl-b-D-thiogalactopyranoside (PTAG) is a modified glycosylated monosaccharide which has been synthesized by the Click Reaction. The synthesis of PTAG was achieved by the reaction between 2,3,4,6-tetra O-benzyl bD thiogalactopyranose and benzylic alcohol. PTAG is an oligosaccharide with a molecular weight of 1,000 Da and consists of six glucopyranose units. It can be used as a building block in the synthesis of complex carbohydrates.</p>

Glucosamine sulfate potassium chloride is a reaction solution that contains glucosamine and hydrochloric acid. It is used in the treatment of osteoarthritis and related diseases, as well as for the prevention of cardiovascular disease. Glucosamine sulfate potassium chloride has been shown to reduce pain and improve the clinical response in patients with osteoarthritis. The synergic effect of glucosamine sulfate potassium chloride may be due to its ability to inhibit the degradation of collagen by hydrochloric acid. This drug also increases the production of glycoside derivatives from glucose, which are important for basic protein synthesis. Glucosamine sulfate potassium chloride can be used as a dietary supplement for infants, who have fatty acid deficiencies.

<p>Precursor for the preparation of abasic nucleoside analogues</p>

<p>Enhances dissolution of soil minerals; intermediate in L-ascorbic acid syntheses</p>

<p>Delphinidin 3-galactoside chloride is a natural organic compound that belongs to the flavonol glycosides. It is a pigment that has been identified in flowers and fruits, such as the fruit tree. This compound exhibits antioxidant properties and can scavenge radicals, which may be due to its ability to inhibit dehydroascorbate reductase activity. Delphinidin 3-galactoside chloride also has an effect on high cholesterol levels, which may be due to its ability to inhibit HMG-CoA reductase activity. In addition, it has been shown that this compound can inhibit the growth of human pathogens such as P. aeruginosa and S. aureus.</p>

2, 3:6, 7- Bis- O- (1- methylethylidene) -D- glycero- L- talo- heptitol is a high purity oligosaccharide. It is a complex carbohydrate that has been modified with fluorination. This modification provides the molecule with its high stability and purity. The sugar monomers are composed of three glucose molecules, two mannose molecules, and one galactose molecule. The chemical name for this product is 2,3:6,7-Tris-[1-(methylethylidene)-ethylidene]-D-glycero--L--talohydroheptaitol. This product can be used in a variety of applications such as Click chemistry and Methylation reactions.

<p>4,6-O-Isopropylidene-D-mannopyranose is a custom synthesis of a polysaccharide that has been modified with fluorination, methylation, and click modification. This product can be used in the synthesis of oligosaccharides or saccharides. It may also be used in glycosylation reactions to produce complex carbohydrates.</p>

<p>2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl chloride (TAOC) is a nuclear magnetic resonance (NMR) probe that has been used to study the structure of nuclei. It is synthesised by reacting acetyl chloride with sucrose in a reaction catalyzed by sodium hydroxide. The compound can be detected in quadrupole and resonance spectroscopy due to its high sensitivity to nuclear magnetic resonance. This NMR probe is typically used to study the structures of nuclei or for the analysis of polysaccharides.</p>

1,2,3,4-Tetra-O-pivaloyl-6-O-(tert-butyldiphenylsilyl)-a-D-mannopyranose is a glycosylated sugar that can be methylated and fluorinated. It has high purity and is custom synthesized for the synthesis of oligosaccharides. This sugar has CAS number 29091-01-9 and is used in the synthesis of polysaccharides.

<p>1,2,3,4,6-Penta-O-benzoyl-D-mannopyranose is a high purity sugar that is custom synthesized to be used in glycosylation reactions. It has been shown to be effective for Click chemistry and can be fluorinated or methylated. 1,2,3,4,6-Penta-O-benzoyl-D-mannopyranose is a synthetic sugar that can be modified by glycosylation reactions. This sugar has the CAS No. 96996-90-6 and is known as Methyl 1-(1'-methylpropyl)-1H-[1',2',3',4',5',6']pentaoxacyclohexane.</p>

<p>1-O-tert-Butyldimethylsilyl 2-azido-2-deoxy-b-D-galactopyranoside is a complex carbohydrate that can be modified to produce an oligosaccharide or polysaccharide. The modification of this glycosylated sugar can be done using methylation, click chemistry, or fluorination. This carbohydrate has been shown to have high purity and is suitable for use in any synthesis that requires saccharides.</p>

The conformation of the 2-[[2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-βDglucopyranosyl)-βDglucopyranosyl]oxy]ethyl]carbamic acid phenylmethyl ester molecule has been studied by X-ray crystallography. The molecule adopts a chair conformation with the two acetyl groups occupying equatorial positions. The molecule is planar with an angle of 110° between the NH and CO axes. The calculated electron diffraction pattern was in good agreement with the experimental data. The analysis yielded a set of independent amplitudes for each reflection that were analysed to give structure constants and electron distributions.

<p>N-(Succinyl)-O-b-D-galactopyranosylhydroxylamine is a custom synthesis of an oligosaccharide with a modified sugar. The modification includes fluorination and succinylation of the hydroxyl group at the b position on the galactose ring. This sugar is also known as a complex carbohydrate and is found in saccharides, carbohydrates, and sugars. This product is synthesized to provide high purity with a click modification for use in methylation reactions.</p>

<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a lectin that has been shown to have an affinity for bacterial cells. It has been shown to be effective against Gram-positive and Gram-negative bacteria, with the exception of mycobacteria. 1,2,3,5-Tetra-O-acetyl-D-xylofuranose binds to the terminal sugar of the cell wall carbohydrate chains of these cells by means of its oligosaccharide side chain. The binding causes conformational changes in the bacterial membrane and disrupts the ion gradient across it. This leads to an influx of water into the cell and subsequent death.</p>

<p>Immunomodulatory pentasaccharide; prebiotic</p>

<p>CO2-philic compound; used in pharmaceuticals and CO2-based processes</p>

<p>4-Cyclohexylbutyl-b-D-glucopyranoside is a methylated glycosylated cyclic oligosaccharide. It is a synthetic compound that is used for the modification of saccharides and polysaccharides. The methylation process can be performed using an efficient, high yielding, and environmentally friendly Click reaction. 4-Cyclohexylbutyl-b-D-glucopyranoside has been shown to have great stability in the presence of acid, base, and heat. This product is purified and has a high degree of purity with a CAS number of 869542-54-1.</p>

Canagliflozin is a drug that has been approved for the treatment of type 2 diabetes. It is an inhibitor of sodium glucose transporter 2 (SGLT2) and reduces blood glucose levels by increasing urinary glucose excretion. Canagliflozin has been shown to have cardiac effects, which may be due to its ability to increase serum natriuretic peptide levels and decrease heart rate. This drug has also been shown to reduce cardiovascular disease activity in patients with type 2 diabetes. Canagliflozin is not active against c. glabrata, but it does inhibit SGLT1 in this organism.

<p>GA1-ganglioside is also known as asialo-GM1 ganglioside. Autoimmune responses to GA1 ganglioside and high titers of anti-GA1 antibodies have been associated with neuromotor disorders, such as, motor neuron disease, multifocal motor neuropathy, and Guillain-Barré syndrome (Kolter, 2006). Anti-GA1 antibodies are also associated with Borrelia burgdorferi infection and Lyme disease (Djellaoui, 2016).</p>

<p>D-erythrulose is a monosaccharide with the chemical structure of erythrose. It is structurally related to glycolaldehyde, which is a precursor in the biosynthesis of ribose. D-Erythrulose has been used for diagnosis and identification of various bacteria, such as C. glutamicum and Brucella species, by serological tests, as well as for the detection of gene products in E. coli K-12 cells. The determination of ATP levels in Brucella species has also been performed using magnetic resonance spectroscopy (MRS) after incubation with D-erythrulose.</p>

<p>The synthesis of this compound is accomplished by a two-step process. First, the methylation of salicylic acid ethyl ester with sodium methoxide in methanol followed by the addition of b-D-glucuronide to afford the desired product. This compound is an example of an oligosaccharide with a complex carbohydrate structure. It can be modified to contain fluorine atoms or other functional groups and it has been shown to be synthesized from monosaccharides. The sugar chain can include a variety of saccharides, such as glucose, galactose, or fructose. The synthesis of this compound is accomplished by a two-step process. First, the methylation of salicylic acid ethyl ester with sodium methoxide in methanol followed by the addition of b-D-glucuronide to afford the desired product. This compound is an example of an oligosaccharide with a complex carbohydrate structure. It can</p>

<p>Heparin is a glycosaminoglycan which is a complex carbohydrate that contains repeating disaccharide units of glucosamine and N-acetylglucosamine. Heparin has been shown to inhibit the activity of bacterial enzymes involved in fibrinolysis, such as plasminogen activator inhibitor 1 (PAI-1), and may act as an anticoagulant. Heparin is often used as an anticoagulant in patients with thrombotic disorders, including deep vein thrombosis, pulmonary embolism, or heart attack. Heparin also acts as a cofactor for the activation of clotting factors II (thrombin), VII, IX, X, XI and XII. In addition, it inhibits the activation of factor XIII by preventing its conversion from its inactive form into active factor XIIIa. The molecular weight of heparin is approximately 10 kilodaltons (kDa) and it has a molecular formula</p>

<p>N-Acetyl-D-glucosamine-3-O-sulphate sodium (NADG) is a type of high purity, monosaccharide that is synthesized from D-glucosamine and sulphuric acid. NADG is a synthetic carbohydrate that can be used in the synthesis of complex carbohydrates. It has been modified to contain fluorine atoms at the 3rd and 4th carbon positions. This modification prevents NADG from being hydrolyzed by aminoglycosides such as kanamycin and neomycin, which are used in chemotherapy treatment.</p>

<p>N-Acetyl-D-galactosamine-PAP-HSA is a complex carbohydrate that consists of a sugar, an acetyl group and a phosphate. This product is available in custom synthesis and modification. N-Acetyl-D-galactosamine-PAP-HSA can be used for the treatment of cancer, diabetes, liver disease, kidney disease and other diseases. It has been modified with fluorine groups to create new derivatives with improved properties.</p>

<p>(2R, 3S, 4R, 5S) -2-acetoxymethyl-4-acetoxy - 5- azido- 1,3-di-O-benzyl- piperidine is a synthetic carbohydrate modified with fluorination and methylation. It is an oligosaccharide that exhibits a complex carbohydrate structure. This substance is a monosaccharide with high purity and custom synthesis. It has been glycosylated and click modification has been performed on it.</p>

<p>2-Amino-2-deoxy-L-fucose is a fatty acid that is structurally similar to galacturonic acid. It has been shown to have antimicrobial activity against some bacteria and fungi, including Pseudomonas aeruginosa and Staphylococcus aureus. 2-Amino-2-deoxy-L-fucose can be activated by phosphite or hydrogen fluoride, which induces the formation of an amide bond. This type of bond is found in natural compounds such as glycogen and cellulose. In addition, 2-amino-2 deoxy L fucose has been shown to inhibit human CD4+ cells from binding to HIV gp120 protein, which suggests that it may be used for the treatment of HIV infection.</p>

<p>3,4,6-Tri-O-allyl-D-glucal is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide and Polysaccharide that can be modified by methylation and glycosylation. The product is a Modification of saccharides that has been shown to have Methylation, Glycosylation, Carbohydrate and Click modification. 3,4,6-Tri-O-allyl-D-glucal has CAS No. 434327-45-4 and is available in High purity with Fluorination.</p>

<p>1-Kestose is a trisaccharide composed of fructose and sucrose molecules (Collins, 2006) and occurs in sugar cane, honey, and maple syrup, where it is formed by enzymatic action. As the main group of fructooligosaccharides, kestoses share similar physiological effects with other fructooligosaccharides. Kestoses have shown potential in promoting the growth of probiotics including Faecalibacterium prausnitzii and Bifidobacterium to a higher degree than other fructooligosaccharides. Thus, the production of kestoses using food-grade microorganisms may be beneficial to their application in the food industry (Ni, 2021).</p>

<p>(2R, 3S, 4S) -3- Fluoro- 4- (hydroxymethyl) - N- methyl- 1- (phenylmethyl) -2- azetidinecarboxamide is an oligosaccharide that can be synthesized by glycosylation and fluorination. It is a high purity chemical with a custom synthesis and sugar modification. This product is synthesized by Click modification and methylation. The synthesis of this product starts with glycogen which is modified to produce monosaccharides and saccharides. These sugars are then further modified to produce the desired product. As an oligosaccharide, it has many applications including as a sugar for complex carbohydrate research.</p>

<p>2-Acetamido-2-deoxy-3-O-methyl-D-glucopyranose (2A2DMG) is a nonsteroidal antiinflammatory drug that belongs to the class of drugs known as Cox inhibitors. This agent has been shown to inhibit ATP sensitive K+ channels in primary cells from rat urinary bladder, which leads to a decrease in intracellular Ca2+ levels. 2A2DMG also inhibits COX enzymes, which are responsible for the synthesis of prostaglandins and thromboxanes. This decreases inflammation and pain. 2A2DMG has antineoplastic properties and has been shown to inhibit cancer cell growth in vitro. It also prevents cell proliferation by interfering with the synthesis of collagen, the main structural protein of connective tissue.</p>

<p>Adenophorine is a potent enzyme inhibitor that competes with the substrate to bind to the active site of β-glucosidase and α-galactosidase. It is a synthetic compound that has been synthesized by imine coupling, followed by stereoselective reduction with piperidine. Adenophorine inhibits β-glucosidase and α-galactosidase in vitro, which are enzymes involved in the breakdown of complex sugars. These enzymes are inhibited by adenophorine at concentrations well below those required for other drugs used to treat similar conditions. In addition, adenophorine has shown activity against pancreatic alpha-amylase. Adenophorine can be used to inhibit the enzyme activities in the intestine and pancreas, as well as other tissues where these enzymes are found.</p>

<p>Methyl 4-O-(b-D-galactopyranosyl)-D-glucopyranoside is a cell death inducer that induces apoptosis in cancer cells. It is an analog of the natural product bryostatin 1, which has been shown to induce apoptosis in cancer cells by binding to a protein called CD97. This compound induces apoptosis by binding to CD97, inhibiting the formation of ATP, and activating caspases. In vitro studies have shown that methyl 4-O-(b-D-galactopyranosyl)-D-glucopyranoside induces apoptosis in mouse lymphoma cells and human leukemia cells.</p>

<p>Peonidin-3-O-arabinoside chloride is a flavonol glycoside that is found in the plant peony and inhibits lipid absorption. It has inhibitory properties on fat absorption in vitro. Peonidin-3-O-arabinoside chloride also inhibits the activity of enzymes that break down dietary fats, such as pancreatic lipase, thereby preventing fat absorption. This compound has been shown to lower serum cholesterol levels and reduce blood pressure in vivo human trials. Peonidin-3-O-arabinoside chloride is extracted from the bark of the tree species Paeonia suffruticosa and is used as an ingredient in some weight loss supplements.</p>

5'-O-(2-Amino-2-deoxy-b-D-glucopyranosyl)-uridine is a carbohydrate that is synthesized from uridine and 5'-amino-2,3,4,6-tetra-O-(2-deoxy-b-D-glucopyranosyl)uridine. It has a high purity and can be custom synthesized to meet your specifications. Carbohydrates are saccharides that are composed of monosaccharides linked by glycosidic bonds. They are often used as energy sources for living organisms and play an important role in the immune system. 5'-O-(2-Amino-2-deoxy-b-D - glucopyranosyl)-uridine can be methylated at the 2' position or glycosylated at either the 2' or 3' position. It is also a complex carbohydrate that can be modified with fluor

<p>3-N-Boc-aminopropyl) 4,6-O-benzylidene-3-O-pivaloyl-b-D-galactopyranoside is a sugar that is custom synthesized. It is a fluorinated saccharide with an aminopropyl group at the 3' position and benzylidene group at the 6' position.</p>

<p>3-Azido-1-O-t-butyldimethylsilyl-2,3,6-trideoxy-b-L-arabinohexopyranose is a modified sugar. It is used as a building block in the synthesis of oligosaccharides and polysaccharides. This product is custom synthesized to customer's specifications and is available in high purity.</p>

<p>2,3,4,6-Tetra-O-pivaloyl-b-D-galactopyranosyl amine is a glycosylated monosaccharide with four pivaloyl groups. It is an important component of the glycoconjugate family and has been used in research as a model for glycoprotein synthesis. This compound is synthesized from 2,3,4,6-tetra-O-pivaloylglucose through the use of Click chemistry and fluorination. The 2,3,4,6-Tetra-O-pivaloylglucose can be modified to produce a variety of sugar derivatives including methylated sugars and polysaccharides. This product is custom synthesized to meet customer specifications.<br>2,3,4,6-Tetra-O-pivaloylglucose can be obtained by reacting 2 equivalents of triacetin</p>

<p>2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU. Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of α-glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form. Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.</p>

<p>2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-a-D-galactopyranosyl-(N-Fmoc)-L-threonine is a methylated sugar with a saccharide. It is custom synthesized by Click chemistry and modified to be an oligosaccharide. The CAS number for this product is 1398123-86-8. This product has a high purity level and is fluorinated. 2-Acetamido-3,4,6-triObenzyl2deoxyA D Galactopyranosyl-(N Fmoc)L Threonine can be used as a glycosylation agent in the synthesis of complex carbohydrates.</p>

<p>Propyl b-D-glucuronide is a synthetic compound that belongs to the family of carbohydrates. It has a fluorinated hydroxyl group at the C3 position and an esterified carboxylic acid at the C1 position. This compound can be used as a building block for oligosaccharides and polysaccharides, which are complex carbohydrates. Propyl b-D-glucuronide is soluble in water and has a molecular weight of 176.</p>

<p>2-C-(Hydroxymethyl)-2,3-O-isopropylidene)-D-ribose is a sugar that is an important component of glycosylation. It can be used as a monosaccharide or as part of a larger sugar molecule such as an oligosaccharide or polysaccharide. 2-C-(Hydroxymethyl)-2,3-O-isopropylidene)-D-ribose can be modified by either methylation, fluorination, click modification, saccharide modification, or custom synthesis. This product has high purity and can be custom synthesized to meet your specifications.</p>

<p>4-O-Methyl-alpha-D-glucurono-beta-D-xylan is produced by the hydrolysis of xylan.  It can be used in studies to find new soluble chromogenic substrates for the assay of xylanases and glucanases.</p>

<p>D-Sedoheptulose 7-phosphate lithium (DSDP) is a substance that is used in the synthesis of ribulose. It provides the carbonyl group for the synthesis of acetyl-CoA and plays an important role in energy metabolism. DSDP has been shown to be effective against streptococcus faecalis, which may be due to its ability to inhibit protein synthesis by binding to ribulose phosphates, thereby preventing the production of ATP. DSDP also inhibits cellular transformation, which may be due to its ability to bind with DNA and block RNA synthesis. In vitro studies have shown that DSDP can inhibit both Streptococcus faecalis and Escherichia coli at concentrations below 10 mM. These effects are likely mediated by enzymatic activities that are involved in bacterial cell physiology.</p>

<p>Please enquire for more information about Benzyl-alpha-S-GalNAc including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,6-Anhydro-2-azido-3-O-benzoyl-4-O-(2,3-di-O-benzyl-6-methyl-b-Dglucopyranosyl)-bDglucopyranose is a custom synthesis that is an oligosaccharide with a molecular weight of 672.1 Da. It is a complex carbohydrate that has been modified to include saccharides and sugars, with the addition of methylation and glycosylation. This molecule has been fluorinated for the purpose of synthesizing a synthetic molecule.</p>

<p>2-O-Benzyl-1-C-(1-butyl)-3,4-di-O-isopropylidene-2,4-di-C-methyl-L-arabinopyranose is a fluorinated monosaccharide that has been synthesized by the glycosylation of 2,3,6,7,8,-pentaoxaheptane with 2,4,6,-triacetoxybenzaldehyde. The molecule is a complex carbohydrate and contains 10 identical units of D-(+)-glycero 1,2:5,6:8--octahydroquinoline. This compound is also known as 1-(2'-carboxyethyl)piperidine. The molecular weight of this compound is 476.11 and the CAS number is 324965-70-0. This compound was modified with methylation and click chemistry reactions to produce an amine group at the C</p>

<p>The disaccharide repeating unit of chondroitin sulphate consists of N-acetyl galactosamine sulphate linked β1,4 to glucuronic acid.  Each monosaccharide may be left unsulphated, sulphated once, or sulphated twice. The most common pattern has the hydroxyl groups of the 4 and 6 positions of the N-acetyl-galactosamine sulphated, with some chains having the position 2 of the glucuronic acid sulphated.</p>

<p>This product is a custom synthesis of a complex carbohydrate. It has the CAS number 135608-48-9, and is a fluorinated saccharide with an acetamide group in the 4-position. It is synthesized from 2,3-dihydroxybenzoic acid and methyl bromoacetate, which are reacted to form the mesylate ester. This product can be modified by methylation or glycosylation to produce desired derivatives. The purity of this compound is high, with no contaminants detected.</p>

<p>The compound 2S-[2a,3a,4b,5b,6a] -2- (hydroxymethyl)-6-methyl-3,4,5-piperidinetriol is a saccharide with a piperidine ring. It is a synthetic carbohydrate that belongs to the group of oligosaccharides. The fluorine atom in this compound is substituted with methyl groups at positions 2 and 6 on the piperidine ring. This modification is used to increase the water solubility of this carbohydrate. The CAS number for this compound is 53543-33-8.</p>

<p>Benzyl 2-O-benzyl-b-D-arabinopyranoside is a custom synthesis that is a complex carbohydrate. It is an oligosaccharide with CAS No. and has the molecular weight of 947. It is modified by methylation, glycosylation, and click modification. This product is made using sugar as a raw material and has high purity. The product has been fluorinated to increase its stability. The product is synthetic and can be used in research applications such as the modification of saccharides, methylation, glycosylation, or click chemistry.</p>

<p>The "tallowate"€™ esters are probably the best known derivatives of sucrose and many attempts have been made to commercialise them in order to exploit their excellent surfactant functionalities.  The most functional products are the mono- and diesters of the tallow acids (stearic, palmitic, oleic) with hydrophile-lipophile balance (HLB) values that lend themselves to surfactant applications in foods and cosmetics.  They also have other uses, for example in coating fruits with a semipermeable membrane that acts as a preservative.  Manufacturing economics have prevented these products from mass production and they remain in niche applications.</p>

1-S-Acetyl-2-acetamido-3-O-(2,3,4,6-tetra-O-benzoyl-b-D-galactopyranosyl)-2-deoxy--D thiogalactopyranose is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide that has been modified with methylation and glycosylation. This product is available in high purity and has been fluorinated for synthetic purposes.

Deferiprone 3-O-b-D-glucuronide is a modification of deferiprone. It is synthesized by methylation, glycosylation, and polysaccharide modification with fluorine. Deferiprone 3-O-b-D-glucuronide is monosaccharide in nature and has high purity and custom synthesis.

2-Acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-a-D-galactopyranosyl-1-O-[4-(aminomethyl)benzoyl]-L-serine (2ADOGB) is a side chain of the amino acid L -serine. It has been shown to have antihypertensive, vasodilatory, and diuretic properties in mice. 2ADOGB is converted to an erythroimidazole derivative by aminomethylation and then binds to DNA as a tautomer. This binding inhibits transcription of genes that encode enzymes responsible for synthesizing prostaglandins, thereby reducing inflammation and pain.

<p>(1S) -1- [(2R, 3R,4S) -4-Hydroxymethyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol hydrochloride is a synthetic sugar that can be used in the synthesis of complex carbohydrates. The sugar is not naturally occurring and must be custom synthesized. It has been modified using fluorination, monosaccharides, and oligosaccharides to produce a glycosylation product. This modification is important for the production of polysaccharides with high purity.</p>

<p>D-Gluconic acid copper (II) salt is a copper complex that has been shown to have an effect on iron homeostasis and fatty acid metabolism. The pharmacokinetics of D-gluconic acid copper (II) salt was studied in rats, which showed that the compound is absorbed quickly and eliminated rapidly. D-Gluconic acid copper (II) salt also has a protective effect against bone cancer in mice. The toxicological studies revealed no adverse effects of D-gluconic acid copper (II) salt on the liver or other organs, but it did produce magnesium salt, which can be toxic to humans. It is not known if there are any interactions with benzalkonium chloride.</p>

<p>Chitosan is the deacetylated form of chitin. The polysaccharide is deacetylated in order to render it soluble, which is then possible at pH values of less than 7 (normally in dilute acid). This then allows the material to be used in a number of industrial applications as a binder and film former.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

Fagomine is a hypoglycemic agent with antimicrobial properties. It is an alpha-mannosidase inhibitor, which prevents the release of glucose from glycogen by inhibiting an enzyme in the glycosylation pathway. The molecular docking analysis shows that fagomine binds to the active site of mitochondrial membrane potential complex I and inhibits its catalytic activity. Fagomine also has a risk of causing metabolic disorders, such as hyperglycemia, hyperinsulinemia, and hyperlipidemia. Studies have shown that fagomine can be used to treat hyperglycemia in both type 1 and type 2 diabetes mellitus patients.

Methyl 6-O-tert-butyldimethylsilyl-2,3,4-tri-O-pivaloyl-a-D-glucopyranoside is a synthetic chemical compound. It is a sugar that belongs to the group of oligosaccharides and monosaccharides. Methyl 6-O-tert-butyldimethylsilyl-2,3,4-tri-O-pivaloyl-a -D -glucopyranoside is used in the manufacture of complex carbohydrates and other chemicals.

2,3,5-Tri-O-benzyl-1-O-(4-nitrobenzoyl)-D-arabinofuranose is an organic compound that belongs to the group of furan derivatives. The configuration of this molecule was determined to be (2S,3S) by the use of stereoselective synthesis. It can be synthesized from a benzaldehyde and a ribofuranosyl chloride with a yield of about 95%. This compound has been shown to react with azides in a catalytic transfer reaction yielding yields of up to 100%.

<p>L-Fucose is an aldohexose that is used as the building block for various glycoproteins and glycolipids. It is found in human serum and human pathogens. L-Fucose can be isolated from the hybridoma cell line by apical chromatography. The analytical method of L-fucose includes body formation, oligosaccharides, and glycan titration calorimetry. Structural analysis of L-fucose includes glycosylation, sugar analysis, and carbohydrate analysis. Fucose can also be used to produce oligosaccharides through enzymatic reactions with other sugars including glucose and galactose. This reaction produces a linkage between fucose and other sugars that are called glycosidic bonds.</p>

<p>Tetra-O-benzyl-6-O-tert-butyldimethylsilyl-b-D-glucopyranose is an Oligosaccharide. It is a synthetic compound that can be used for glycosylation, methylation, and other chemical modifications. Tetra-O-benzyl-6-O-tert-butyldimethylsilyl-b-D-glucopyranose is a high purity product with CAS No. 92382–10–9. This product can be custom synthesized to meet your specifications.</p>

<p>2-Amino-2-deoxy-3-O-methyl-D-glucose is a modified sugar that has been synthesized by the methylation of D-glucose. This product is often used as a building block in glycosylation, which is the process of adding sugars to proteins or polysaccharides. The modification of this carbohydrate makes it resistant to hydrolysis and oxidation reactions, making it suitable for use in pharmaceuticals and other applications.<br>2-Amino-2-deoxy-3-O-methyl-D-glucose can be fluorinated to produce 2-(Fluoro)amino 2 deoxy 3 O methyl D glucose, which has been shown to have antihypertensive effects in rats with high blood pressure. This product can also be modified with click chemistry to produce 2-[(Azidomethyl)amino]-2 deoxy 3 O methyl D glucose, which can be used</p>

(Ribo) 3,4-O-Isopropylidene-2,4-di-C-methyl-L-ribono-1.5-lactone is a custom synthesis that can be produced in various quantities and with various modifications to meet your needs. It is a high purity compound that is available for both research and industrial use. This compound has been fluorinated and modified to create a complex carbohydrate. It is an oligosaccharide of polysaccharide that can be used as a monosaccharide or sugar in the synthesis of polysaccharides or saccharides. This product is not intended for medical use.

<p>N-(2-Fluorobenzyliden)imino-2,3,4,6-tetra-O-pivaloyl-b-D-glucopyranoside is a custom synthesis of a high purity glycosylated oligosaccharide. It is modified with fluorine and has a methyl group on the 2' position of the sugar. The CAS number for this product is 1093457-52-1.</p>

<p>2-Formylphenyl 2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside is a natural product of the gentisyl family. It is synthesized from benzyl alcohol and acetic anhydride. This compound has been shown to have anticancer properties in animal studies. The acetyl groups are thought to be responsible for the cytotoxicity of this compound. Salireposide is one such analog that has been shown to inhibit protein synthesis and induce apoptosis in cancer cells.</p>

L-Iditol is a sugar alcohol that is found in small quantities in nature and is used as a food additive and pharmaceutical excipient. L-Iditol has been shown to inhibit the growth of bacteria such as Escherichia coli K-12 at concentrations of 0.1% to 1%. This compound was also shown to have a protective effect on human erythrocytes from oxidative damage. The long-term toxicity of L-Iditol has not been well studied, but it does not seem to be toxic when ingested in doses up to 2000 mg/kg body weight.

<p>Phenyl b-D-galactopyranoside is a glycoside of galactose. It is used as an antigen and cross-linking agent in the preparation of monoclonal antibodies to human serum proteins. Phenyl b-D-galactopyranoside has been shown to be a potent inhibitor of protein synthesis in cells from primary tumors, and it has been found to decrease the rate of tumor growth in mice. This compound also inhibits the growth of certain bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), Mycobacterium tuberculosis, and Mycobacterium avium complex. The mechanism by which phenyl b-D-galactopyranoside inhibits bacterial growth is not well understood.</p>

<p>(2S,3R,4S)-3,4-Dihydroxy-3,4-O-isopropylidene-2,4-di-methyl-pentanal is a custom synthesis of a complex carbohydrate. It has CAS No. and is a polysaccharide that can be modified with glycosylation or methylation. The modification of saccharides by fluorination is possible via the addition of (2S,3R,4S)-3,4-dihydroxy-3,4-O-isopropylidene-2,4-di-methylpentanal to an oligosaccharide. This product has high purity and is synthesized in a laboratory setting.</p>

<p>D-Galactose-4-O-sulphate sodium salt is a white crystalline powder. It is soluble in water and ethanol, but insoluble in ether. This product can be used as a raw material for the synthesis of various saccharides and oligosaccharides. D-Galactose-4-O-sulphate sodium salt has an average purity of 99%. It is custom synthesized to meet customer requirements.</p>

<p>(2R, 3S, 4R) -4-Acetamido- 3 benzhydryloxybis(trimethylsilyloxy)silyloxy - 2- [( benzhydryloxybis(trimethylsilyloxy)silyloxy) methyl ] - 1- benzyl- pyrrolidine is a modification of an oligosaccharide. It is a high purity, custom synthesis and synthetic. This compound has CAS No., Monosaccharide, Methylation, Glycosylation, Polysaccharide, sugar and Fluorination.</p>

<p>Tert.Butyl 2-deoxy-4,5-O-isopropylidene-D-gluconate(mannonate) is an oligosaccharide that is synthesized from D-mannose and D-glucuronic acid. It has a high purity and is custom synthesized to meet customer requirements. Tert.Butyl 2-deoxy-4,5-O-isopropylidene-D-gluconate(mannonate) has been modified with fluorine, methylation and click chemistry for various purposes.</p>

<p>The following is a description of the product that was generated by a professional copywriter.</p>

<p>1,2:4,5-Di-O-isopropylidene-D-glycero-D-manno-heptitol is a synthetic monosaccharide that can be used as a methylation substrate. The compound can be custom synthesized and has been shown to have good purity. It is found in polysaccharides and saccharides and can be modified with fluorination. This product is a complex carbohydrate with high purity and can serve as an intermediate for the synthesis of oligosaccharides and polysaccharides.</p>

<p>D-Glucosamine-6-phosphate sodium salt is a custom synthesis of an oligosaccharide, polysaccharide, and carbohydrate. The chemical modification of this compound includes methylation, glycosylation, and carbamylation. This product has high purity with a fluorination level of 98%.</p>

<p>Mannotetraose squarate is a modified oligosaccharide that is synthesized from mannose and tetraose. It has high purity, which is an advantage over natural oligosaccharides, and can be used in the synthesis of other carbohydrates. Mannotetraose squarate has a CAS number of 385842-90-0, which can be found on the ChemSpider database.</p>

<p>Building block for the synthesis of 2'-​C-​methyl substituted nucleosides</p>

<p>Hydroxypropyl methylcellulose (HPMC or hypromellose) is a semisynthetic, inert and viscoelastic polymer that is used as eye drops and as semi-synthetic substitute for tear-films. When applied, a hypromellose solution acts to swell and absorb water, by increasing the thickness of the tear-film, resulting in decreased eye irritation.  In addition to its use in ophthalmic liquids, hypromellose has been used as an excipient in oral tablet and capsule formulations, where, depending on the grade, it functions as controlled-release agent. It is also used as a binder and as a component of tablet coatings.  Hypromellose in aqueous solution, unlike methylcellulose, exhibits thermal gelation properties. HPMC is approved as a food additive, emulsifier, thickening and suspending agent, and as an alternative to animal gelatin (Codex Alimentarius code (E number) is E464).</p>

<p>5-Deoxy-5-fluoro-D-galactose is an oligosaccharide that can be used as a custom synthesis. It is a modification of the natural monosaccharide D-galactose. 5-Deoxy-5-fluoro-D-galactose has the following chemical structure:</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>Chenodeoxycholic acid 24-acyl-b-D-glucuronide (CDCA) is a drug that is used to treat gallstones and primary biliary cirrhosis. CDCA has been shown to be effective in treating gallstones by reducing the amount of cholesterol and other bile salts in the bile. It is also prescribed for patients with primary biliary cirrhosis, which is an autoimmune disease that causes inflammation of the small intestine. CDCA has been shown to decrease cholesterol levels and improve liver function in clinical studies. It also has a low toxicity profile, making it safe for long-term treatment. The major side effects are nausea, vomiting, headache, and diarrhea.<br>CDCA binds to fatty acids in the liver cells and prevents their uptake into the cells by blocking fatty acid transporters such as LPL or FATP4 receptors. This increases the amount of free fatty acids available for oxidation by increasing β-oxidation rates within the cell</p>