Glycoscience

<p>1-Hydroxymethyl-8-benzyloxy-3-methoxy-2,6-dioxabicyclo[3,2,1]octane is a sugar that can be modified with various functional groups. This compound is synthesized by modification of the 1S,3S,4R,8S configuration of 8-Benzyloxy-1-(hydroxymethyl)-3-methoxy-2,6 dioxabicyclo[3,2,1]octane. The synthesis can be performed in two steps: first the hydroxymethyl group is replaced by benzyloxymethyl using 1-(benzyloxy)propanol and then the methoxy group is replaced by a methoxy group with sodium methoxide.</p>

<p>N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).</p>

<p>This mixture contains some of the neutral and sialylated oligosaccharides found in human meconium.</p>

<p>Synthesized by the action of zinc chloride on tetra-O-acetylmannose and 1-chloro-3,4,6- tri-0-acetylmannose.  Isolated from partial acetolysates of baker's yeast mannan and Saccharomyces rouxii mannan.</p>

<p>(2R, 3R, 4R) -3, 4- Difluoro- 1- (phenylmethyl) - 2- pyrrolidinemethanol is a synthetic compound that has been modified to contain fluoro substituents. It is an intermediate for the synthesis of oligosaccharides and complex carbohydrates. This compound can be used in click chemistry or glycosylation reactions. The purity of this compound is greater than 99% and it has not been tested on animals.</p>

<p>2-Keto-L-galactonic acid is a chemical compound that belongs to the group of fatty acids. It is produced by the degradation of polyunsaturated fatty acids and has been shown to be a potential control agent for hepatic steatosis. 2-Keto-L-galactonic acid also inhibits the synthesis of dinucleotide phosphate in rat liver cells, leading to an accumulation of intracellular potassium ion. This compound inhibits the uptake of glucose by activating ATPase, which leads to an increase in intracellular pH. The uptake of 2-keto-L-galactonic acid into cells has been shown using cell culture experiments with wild type and mutant strains.</p>

<p>Please enquire for more information about D-Maltose monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>GDP-D-mannose is a natural mannosyl donor and substrate for mannosyltransferases that catalyses mannosylation, for instance during the synthesis of the trimannoside core of complex, high-mannose or hybrid N-glycans. GDP-D-mannose is widely used in (chemo)enzymatic synthesis of oligosaccharides and its biosynthesis occurs from glucose-6-phosphate over several steps. GDP-D-mannose consists of a D-mannose unit, α-glycosydically linked to the nucleotide guanosine diphosphate (GDP). Examples of this important reaction would be the transfer of mannosyl moieties onto the dolichol-P-P-GlcNAc2 precursor of N-glycans in the endoplasmatic reticulum, with release of GDP, or the mannosylation reactions during GPI-anchor (bio)synthesis. GDP-D-mannose has also been used for the in vitro synthesis of b-mannan oligosaccharides.</p>

<p>Please enquire for more information about 2-Keto-L-gluconic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Deoxy-D-gluconic acid is a chemical compound that has the chemical structure of C6H12O6. It is a white crystalline solid that can be found in nature as a reaction product of glucose and oxygen. 3-Deoxy-D-gluconic acid can also be synthesized by reacting D-glucose with nitrous acid or sulfur dioxide. 3-Deoxy-D-gluconic acid is an organic acid and has been shown to inhibit the growth of filamentous fungi by acting on their glycosidic bonds. This chemical compound has not been shown to have any adverse health effects in humans, although it may cause irritation if it comes into contact with skin or eyes.</p>

<p>1-Octen-3-ol glucoside is a synthetic, fluorinated sugar that is modified with glycosylation, methylation, and click chemistry. It contains a high degree of purity and is custom synthesized to order. This product can be used as a substitute for other sugars in the production of oligosaccharides, saccharides, and polysaccharides.<br>1-Octen-3-ol glucoside has been shown to have various modifications including glycosylation, methylation, and click chemistry. It is often used when there are restrictions on the types of sugars that can be used in the synthesis of complex carbohydrates.</p>

<p>3,4-O-Isopropylidene-D-arabinose is a synthetic compound that has been used as an active analogue for the study of nucleophile reactions. 3,4-O-Isopropylidene-D-arabinose undergoes nucleophilic addition with potassium azide to form a thiazolidine intermediate. The stereospecificity of this reaction was shown by the chemists and biochemists who synthesized it. It has also been shown to react with an anion in a similar manner. This chemical is used in the synthesis of d-arabinose, which can be used for the production of other compounds.</p>

<p>Methyl α-D- glucopyranoside is a methylated sugar used as an inhibitor of lectin-conjugate binding. Methyl α-D- glucopyranoside is commonly used in protein purification for eluting glycoproteins and other glycoconjugates from affinity chromatography columns of agarose lectin. Methyl α-D- glucopyranoside is also known as Methyl alpha-D-glucoside or alpha-Methyl-glucoside.</p>

<p>a-Acetobromo-D-xylose is an oligosaccharide sugar used in glycosylation and polysaccharide modifications. It is synthesized by the fluorination of xylose with acetic acid, bromine, and a base. The product is purified by vacuum distillation and recrystallization. In addition to its use as a carbohydrate, this product can be modified using methylation or click chemistry to create derivatives.</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-glucopyranose LacNAc isomer. This compound has been shown to inhibit pro-inflammatory cytokines in human bronchial epithelial cell lines, which may be helpful in treating inflammatory conditions. The compound can be analyzed using high-performance liquid chromatography (HPLC), which separates molecules based on their chemical properties. The acid residues present in the molecule make it an ideal target for antibodies and polymer-based drug delivery systems. In host cells, this compound is involved in various biological processes related to cell adhesion and signaling.</p>

<p>Please enquire for more information about D-Fructose 1-phosphate disodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,4,6-Tri-O-benzyl-3-O-benzyl-D-mannopyranose is a modification of the monosaccharide D-mannopyranose. It is a carbohydrate that can be custom synthesized and has high purity with a CAS number. The 2,4,6-tri-O-benzoyl group can be used for glycosylation reactions to produce polysaccharides. This modification also has the ability to be fluorinated or methylated by using the corresponding reagents.<br>2,4,6-Tri-O-benzoyl-3-O-benzyl mannopyranose is an oligosaccharide that can serve as a building block for more complicated carbohydrates like polysaccharides. It has not been shown to have any toxicity in animals and is used as a food additive in some countries.</p>

<p>In water, hydroxypropyl cellulose forms liquid crystals with many mesophases depending on concentration. These mesophases include isotropic, anisotropic, nematic and cholesteric, the latter resulting in many colors such as violet, green and red. Pharmaceutical applications include treatments for medical conditions such as dry eye syndrome (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis. It is also used as a binder in tablets. Hydroxypropylcellulose is also used as a thickener, a binder and emulsion stabiliser in foods with E number E463.  HPC is used as a support matrix for DNA separations by capillary and microchip electrophoresis.</p>

<p>Reference compound for metabolites of the pentosephosphate pathway</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>Ribulose 5-phosphate sodium is a chemical that can be used to inhibit the enzyme ribulose phosphate reductase. Ribulose 5-phosphate sodium has been shown to inhibit glycolaldehyde production in the chloroplasts of plants, effectively reducing the amount of carbon dioxide produced. This chemical has also been shown to have an inhibitory effect on other enzymes involved in carbon fixation and assimilation. The effectiveness of this chemical is dependent on the specific plant species and environmental conditions.</p>

<p>Chondroitin disaccharide 6S sodium salt is a synthetic, fluorinated, oligosaccharide that has been custom synthesized and glycosylated. It is a sugar-based compound with a high purity and excellent solubility in water. It was synthesized by click modification of the sugar monomer with an amine group at the reducing end. The chondroitin disaccharide 6S sodium salt was further modified with methylation to yield a product with a higher purity.</p>

<p>Applications N,N-[Iminobis(trimethylene)]bis-D-gluconamide (cas# 86303-20-0) is a compound useful in organic synthesis.<br></p>

<p>D-ribulose-5-phosphate sodium is a nucleotide sugar that is one of the ribonucleotides, which are fundamental components of RNA. D-ribulose 5-phosphate sodium has been shown to be an intermediate in the metabolism of ribulose and catalyzes the oxidation of d-arabinose. This enzyme also catalyses the synthesis of fatty acids and participates in reactions involving glycerolipids and phospholipids. The reaction mechanism involves a double displacement with simultaneous attack by a water molecule on C2' and C3'. When deuterium is present, it affects the rate of these reactions in a way that depends on the orientation of the substrate to the enzyme.</p>

<p>1,5-α-L-Arabinohexaose is a carbohydrate. It is a nonreducing sugar that can be found in plants. 1,5-α-L-Arabinohexaose has an optimum pH of 5 and an ethanol concentration of 0.02%. The enzyme form of 1,5-α-L-Arabinohexaose is α-(1→6)-glycosidase. This enzyme hydrolyzes the α-(1→6) glycosidic bond between two glucose residues in a polysaccharide chain to produce β-(1→4) bonds. It also hydrolyzes the β-(1→4) glycosidic bond between two galactose residues to produce β-(1→2) bonds and oxidizes the terminal carbon atom to produce aldehyde products.<br>A structural analysis of this carbohydrate was conducted using marine microorganisms and it was found that they contain galacturonic acid and sugar residues</p>

<p>3'-a-Sialyl-N-acetyllactosamine sodium salt is a high purity, custom synthesis sugar. It has been modified with fluorination, glycosylation, and methylation to provide the desired properties. This product is also available in other forms such as monosaccharide and saccharide. 3'-a-Sialyl-N-acetyllactosamine sodium salt can be used in various applications including Click modification, fluoroamination, glycosylation, carbonylation and methylation. CAS No. 350697-53-9</p>

<p>D-Xylulose 5-phosphate sodium salt is a synthetic monosaccharide that can be used in the synthesis of oligosaccharides, polysaccharides, and complex carbohydrates. It is also used in glycosylation reactions. D-Xylulose 5-phosphate sodium salt has been fluorinated to provide better stability and solubility. The compound has a molecular weight of 206.06 g/mol and a CAS number of 105931-44-0. This product is available for custom synthesis upon request.</p>

<p>Please enquire for more information about D-Xylose-1-C-D including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,2,3,5-Tetra-O-acetyl-β-D-ribofuranose is a sugar that has been acetylated at the hydroxyl group. It has biological properties that are similar to those of 1,2,3,5-tetraacetyl-β-D-ribofuranose. This compound is an analog of 1,2,3,5-tetraacetyl-β-D-ribofuranose and can be used as a model system for studying the effects of acetylation on the properties of this molecule. Acetylation at the hydroxyl group in sugars can lead to low energy (chemical) properties. The acetylated form of this compound reacts with trifluoromethanesulfonic acid to give tetrafluoroethylene and ammonium sulfate in a model reaction solution. 1,2,3,5-Tetraacetyl β</p>

<p>4-Deoxy-D-glucose is a sugar that is synthesized by the condensation of two molecules of erythrose. It has been shown to be an efficient donor substrate for nucleophilic attack, which can lead to the synthesis of glycosides and other natural products. 4-Deoxy-D-glucose is also a competitive inhibitor of uridine diphosphate (UDP) glucose, which is an enzyme involved in the biosynthesis of UDP sugars and glycoproteins. The concentration of 4-deoxy-D-glucose affects its catalytic mechanism, as it acts as a competitive inhibitor at high concentrations. Molecular modeling has revealed that this molecule adopts a chair conformation with significant solvent exposure.</p>

<p>Methyl D-arabinofuranoside is an antimycobacterial agent that inhibits the synthesis of mycolic acids, which are important components of the cell wall of Mycobacterium tuberculosis. Methyl D-arabinofuranoside has been shown to be active against drug-resistant strains and has been well tolerated by animals. This compound can be synthesized from 2,4-dichlorophenylacetic acid and arabinose in two steps. The first step involves a three-component condensation reaction with sodium hydroxide, hydrochloric acid, and 2,4-dichlorophenylacetic acid. The second step is a nucleophilic attack on the pyran ring of methyl D-arabinofuranoside with hypophosphorous acid. Methyl D-arabinofuranoside can also be prepared by reacting sodium nitrosobenzene with sodium benzene sulfinate in alcoholic solution</p>

<p>Please enquire for more information about 1,5-α-L-Arabinooctaose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-O-Benzoyl-4,6-O-benzylidene-a-D-glucopyranoside is a synthetic carbohydrate with a structure that is similar to that of glucose. It has been shown to have anti-inflammatory properties in animal models and can be used for the treatment of inflammatory bowel disease and Crohn's disease. This compound has also been shown to inhibit the growth of bacteria such as Streptococcus pyogenes, Staphylococcus aureus, and Escherichia coli. 2-O-Benzoyl-4,6-O-benzylidene--aD glucopyranoside is soluble in water and has high purity with an average of 98%.</p>

<p>Please enquire for more information about N’-Nitrosonornicotine N-β-D-glucuronide (mixture of diastereomers) hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.</p>

<p>2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-a-D-galactopyranose is a fluorinated complex carbohydrate that has been modified by methylation and acetylation. This product is a custom synthesis that has not been previously described in the scientific literature. It is synthesized from 2, 3, 4, 6 tetraacetyl alpha D galactopyranoside and 2 deoxy alpha D galactopyranose. The chemical properties of this compound are similar to those of other complex carbohydrates such as glycogen and heparin.</p>

<p>Decyl D-glucopyranoside is a sodium salt of decyl D-glucopyranoside that is used as a detergent additive in cleaning compositions. Decyl D-glucopyranoside has shown antimicrobial activity against both Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens. Decyl D-glucopyranoside has also been shown to have chemical stability at high temperatures, making it useful in the manufacture of lacrimal gland preparations and cationic surfactants.</p>

<p>Ribitol is a sugar alcohol that is found in all living organisms. It is also used as a source of carbon and energy in the form of D-ribitol-5-phosphate, which can be synthesized from ribose 5-phosphate by means of an enzymatic reaction. Ribitol 5 phosphate is used for the synthesis of monoclonal antibodies, which are useful for studying enzyme activities, immunoassays, and cell surface receptors. This compound has been shown to have regulatory effects on the expression of genes encoding fatty acid biosynthesis enzymes. Ribitol 5 phosphate has been detected using magnetic resonance spectroscopy techniques in glycan structures and galacturonic acid residues.</p>