Glycoscience

Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.

The glucuronidation of 1-O-(trans-3-hydroxycotinine)-b-D-glucuronide ammonium salt is mediated by the enzyme UDP-glucuronosyltransferase. This reaction is catalyzed by the transfer of a glucuronic acid residue from UDP-glucuronic acid to a hydroxyl group on the side chain of 1-O-(trans-3-hydroxycotinine)-b-D-glucuronide ammonium salt. The kinetic analysis of human urine samples has shown that this reaction is significant. This metabolite can be detected in urine samples using next generation sequencing and its concentration can be used as an indicator for the consumption of tobacco or nicotine containing products. Epidemiological studies have shown that this metabolite has significant effects on cancer risk. Genotyping and genotype studies have shown that this metabolite is responsible for genetic polymorphisms that are associated with increased cancer risk.

Zeta-cyclodextrin (ζ-CD) consists of 11 glucose units. Its larger cavity size offers potential for encapsulating larger guest molecules or forming more complex inclusion compounds.

Substrate for UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC)

Core antigen ABO trisaccharide conjugated to BSA

Pregnanediol 3α-O-β-D-glucuronide is a glucuronide metabolite of progesterone, which is a key steroid hormone in the reproductive system. This compound is derived from the metabolic conversion of progesterone, primarily within the liver, where it undergoes glucuronidation. This process involves the addition of glucuronic acid, mediated by the enzyme UDP-glucuronosyltransferase, enhancing the compound’s solubility for renal excretion.

6'-O-Sulfated Lewis X is a synthetic, sulfated, monosaccharide that is modified with fluorine and methyl groups. It is used in the synthesis of oligosaccharides and polysaccharides. 6'-O-Sulfated Lewis X has been found to be effective in the prevention of glycosylation and sugar formation. This compound can also be used for click modification, as well as for modifying proteins or DNA. The CAS number is 59037-07-4.

Xylitol is a sugar alcohol that can be found in some plants, including berries and corn husks. It is also produced by the body during normal metabolism. Xylitol has been shown to have antimicrobial properties against aerobacter aerogenes, a bacterium that inhabits the human gastrointestinal tract. Xylitol inhibits bacterial growth by binding to glucose-6-phosphate dehydrogenase, which prevents the conversion of glucose into energy for cell growth and reproduction. Xylitol also affects the water balance of cells by inhibiting their ability to extract water vapor from their environment. Xylitol is metabolized by a number of bacteria strains, which leads to the production of hydrogen peroxide or xylose as an end product. The biochemical properties of xylitol are still being researched and it is not yet known how this compound interacts with other biological compounds.

Propofol-4-Hydroxy-4-D-glucuronide is a fluorinated monosaccharide that has been synthesized using the glycosylation, polysaccharide and modification methods. This compound is a custom synthesis that has been modified with methylation and click chemistry. The CAS number for this product is 54910-87-6. This product is a complex carbohydrate with high purity.

Leucine-​derived gamma-hydroxynitrile glucoside

Isopropyl-β-D-thioglucuronic acid is a β-D-glucuronidase inducer. It enhances the sensitivity of β-glucuronidase assays in E. coli.

Methyl 2,3-di-O-acetyl-4,6-O-(4-methoxybenzylidene)-a-D-mannopyranoside is a custom synthesis that contains a fluorinated sugar with a methyl group attached to the 4 position. The oligosaccharide is synthesized through click chemistry and has been modified with an acetate at the 6 position. The CAS number is 108739-53-0. The carbohydrate is a complex carbohydrate that can be found in nature or synthesized in the laboratory.

D-myo-Inositol 1,4,5,6-tetraphosphate sodium salt is a colony-stimulating factor that is involved in the regulation of metabolism and growth. It has been shown to increase the number of blood cells in rats with myeloid leukemia by acting on stem cells. D-myo-Inositol 1,4,5,6-tetraphosphate sodium salt binds to stem cell factor receptors on cell membranes to activate the receptor activity and initiate protein synthesis. This leads to increased production of hematopoietic cells and monoclonal antibodies. D-myo-Inositol 1,4,5,6-tetraphosphate sodium salt also stimulates erythropoiesis by regulating red blood cell production through its interaction with epidermal growth factor (EGF).

Used as source of carbon in culture medium.

Used to differentiate bacteria on the basis of carbohydrate fermentation abilities.

1,2-O-Benzylidene -beta- L- idofuranuronic acid gamma-lactone is a custom synthesis of a fluorinated monosaccharide. The modification of the sugar is accomplished by methylation and click chemistry. The monosaccharide can be used as a building block for oligosaccharides and polysaccharides. It is also used as an intermediate in the glycosylation process that produces complex carbohydrates.

2-Acetamido-1,3,6-tri-O-benzyl-2-deoxy-b-D-glucopyranoside is a synthetic monosaccharide that can be modified to the desired structures. It is used as a building block for the synthesis of polysaccharides and oligosaccharides. It is also used as an intermediate in the preparation of saccharides. 2 - Acetamido - 1,3,6 - tri - O - benzyl - 2 - deoxy - b - D - glucopyranoside is available in high purity and custom synthesis.