Ácidos grasos

D-propargylglycine is a chemical compound that belongs to the group of valency modifiers. It is a modulator that can be used in cancer research and as an anti-inflammatory agent. It has been shown to have protein–protein interaction by binding to casein kinase, which may lead to its use in cancer therapy. D-propargylglycine can also interact with other proteins and inflammatory agents, leading to potential applications in the treatment of inflammatory conditions such as arthritis.

<p>Palmitoleic acid is a fatty acid with a molecular weight of 256. It is an unsaturated fatty acid that contains 16 carbon atoms and two double bonds. Palmitoleic acid has been shown to be effective in treating bowel disease, such as ulcerative colitis and Crohn's disease, by influencing the production of inflammatory cytokines. This active form inhibits the activity of toll-like receptor 4 (TLR4) and lipopolysaccharide (LPS)-induced signal peptide activation of nuclear factor kappa B (NF-κB), which leads to reduced inflammation. Palmitoleic acid has also been shown to have anti-inflammatory properties in vitro and in vivo, which may be due to its ability to inhibit IL-1β production by macrophages.</p>

<p>DL-Propargylglycine is a molecule that has been used as a model system for studying the interaction of neurokinin-1 receptor with response elements. It has also been shown to have inhibitory properties on polymerase chain, which is important in the process of energy metabolism. This compound has been shown to increase cytosolic Ca2+ and inhibit nuclear DNA synthesis in certain cells. DL-Propargylglycine can be used to study the effects of growth factor-β1 on myocardial infarcts and bowel disease.</p>

<p>Pimeloyl-CoA is a CoA derivative formed from pimelate, serving as a precursor in the biotin biosynthesis pathway of certain bacteria.</p>

5-Bromo-2-methylbenzoic acid ethyl ester is a fine chemical used as a versatile building block in organic synthesis. It is also used as a reagent for the conversion of alcohols to alkyl bromides, and for the preparation of 2-bromoacetophenones from 2-bromobenzenes. 5-Bromo-2-methylbenzoic acid ethyl ester can be used as a useful intermediate in the synthesis of other compounds or in reactions with other chemicals. This product has high quality and can be used as a useful scaffold for synthesizing new compounds.

<p>Applications 6-ACETYL-PICOLINIC ACID ETHYL ESTER (cas# 114578-70-0) is a useful research chemical.<br></p>

<p>Applications Ethyl Propargylate is used in the synthesis of substituted anthraquinones. Also used in the preparation of inhibitory pyrazolo[1,5-a]pyridines for anti-inflammatory activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chang, M. et al: Synth. Comm., 43, 3363 (2013); Kojima, A. et al.: Bioorg. Med. Chem. Lett., 23, 5311 (2013);<br></p>

<p>Applications cis-8,11,14-Eicosatrienoic Acid Ethyl Ester-d5 is the isotope labelled analog of cis-8,11,14-Eicosatrienoic Acid Ethyl Ester (E477920); the ethyl ester derivative of cis-8,11,14-Eicosatrienoic Acid (E477930) which is a fatty acid with selective tumoricidal activity.<br>References Das, U., et al.: Cancer Lett., 56, 235 (1991); Rudra, P., et al.: Anticancer Res., 21, 29 (2001); Menendez, J., et al.: Breast Cancer Res. Treat., 72, 203 (2002)<br></p>

<p>Applications New lipids in food protein hydrolyzates.<br>References Velisek, J., et al.: J. Agric. Chem., 28, 1142 (1980),<br></p>

<p>Applications 1,2-DIHYDRO-2-OXO-6-(TRIFLUOROMETHYL)-3-PYRIDINECARBOXYLIC ACID ETHYL ESTER (cas# 116548-02-8) is a useful research chemical.<br></p>

<p>Applications Carbon(isothiocyanatidic)acid Ethyl Ester (cas# 16182-04-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Benzenebutanoic Acid Ethyl Ester is used in the synthesis of thiazolium salts with potent antimalarial activity. Also used in the preparation of novel lactate dehydrogenase A inhibitors. This compound is suitable for lactate dehydrogenase (LDH) related research.<br>References Hamze, A. et al.: J. Med. Chem., 48, 3639 (2005); Ward, R. et al.: J. Med. Chem., 55, 3285 (2012);<br></p>

<p>Applications 3-(N,N-Dimethylpalmitylammonio)propanesulfonate is a zwitterionic surfactant used in the preparation of a highly efficient adsorbent for herbicides, DHAPS-Mt.<br>References Gu, Z., et. al.: Ind. Eng. Chem. Res., 54, 4947 (2015)<br></p>

<p>Applications Sodium Hexadecanoate-16,16,16-d3 (CAS# 347841-37-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 6-Bromo-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxylic Acid Ethyl Ester is an intermediate in the synthesis of loratadine (L469575) related compounds.<br>References Bruttmann, G., et al.: J. Allergy Clin. Immunol., 83, 411 (1989), Haria, M., et al.: Drugs, 48, 617 (1994)<br></p>

<p>Applications N-Hexadecanoyl-2-amino-1,3-propane-d5-diol (CAS# 949524-35-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Sulfosuccinimidyl Palmitate Sodium is an analog of Sulfosuccinimidyl Oleate Sodium (S689200).<br></p>

<p>Applications Estradiol 17-Palmitate-d31 is the isotope analog of Estradiol 17-Palmitate. Estradiol 17-Palmitate is a metabolite of estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.<br>References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),<br></p>

<p>Applications Fmoc-D-propargylglycine<br></p>

<p>Applications Hexadecanoic-11,11,12,12-d4 Acid (CAS# 75736-57-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Benzoyl-1H-pyrrole-2-acetic Acid Ethyl Ester is an intermediate in the synthesis of rac Ketorolac 6-Benzoyl Isomer (K235620). rac Ketorolac 6-Benzoyl Isomer (Ketorolac EP Impurity C) is an isomeric impurity of Ketorolac (K235620).<br></p>

<p>Applications Propargyl Alcohol-13C3 is labelled Propargyl Alcohol (P762550) which is used as a corrosion inhibitor, a metal complex solution, a solvent stabilizer and an electroplating brightener additive. It is also used as an intermediate in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, T., et al.: Res. Chem. Interm. (2013); Choudhary, Y., et al.: SPE Product. Operat., 28, 268 (2013); Hed, Y., et al.: J. Mater. Chem. Mater. Bio. Med., 1, 6015 (2013)<br></p>

<p>Applications 2,4-Dimethyl-1H-pyrrole-3-carboxylic Acid Ethyl Ester is used as an intermediate in the synthesis of receptor tyrosine kinase (RTK) inhibitors and their metabolites.<br>References Elsinghorst, P. et al.: J. Lab. Comp. Radiopharm., 52, 360 (2009); Sun, L. et al.: J. Med. Chem., 41, 2588 (1998);<br></p>

<p>Applications (3α,5β,17α)-13-Ethyl-18,19-dinorpregnane-3,17-diol is an anabolic androgenic steroid.<br>References Fragkaki, A. et a.: J. Ster. Biochem. Mol. Biol., 115, 44 (2009);<br></p>

<p>Applications Fmoc-l-propargylglycine has been used to study the bioorthogonal chemical tagging of protein cholesterylation in living cells.<br>References William P. H., et al., ChemComm., 47, 4081-4083 (2011)<br></p>

<p>Applications tert-Butyl 8-Hydroxyoctanoate is used as a reagent in the synthesis of unsaturated hydroxy fatty acid derivatives as immuno adjuvants.<br>References Yamada, H., et al.: PCT Int. Appl. WO 2002017961 A1 20020307. Mar 7, 2002<br></p>

<p>Applications 3-Ethoxyacrylic Acid Ethyl Ester-13C2 is an intermediate used in the synthesis of 2-Chloro-5-thiazolecarboxylic Acid-13C3,15N (C411468), which is an isotopically labeled analog of 2-Chloro-5-thiazolecarboxylic Acid (C411465), which was studied as one of the metabolites of thiamethoxam, clothianidin, and dinotefuran in mice.<br>References Ford, K., et al.: Chem. Res. Toxicol., 19, 1549 (2006);<br></p>

<p>Applications Sodium Hexadecanoate-d31 (CAS# 467235-83-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Used in the synthesis of esters of α,α-dimethyl-β-keto acids.<br></p>

<p>Applications 1-Bromohexadecane-16,16,16-d3 (CAS# 284474-40-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)quinoline-3-carboxylic Acid Ethyl Ester is an intermediate in the synthesis of Rosoxacin (R693580), an antibacterial agent used against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae.<br>References Koba, M., et. al.: J. Mol. Modeling, 16, 327 (2010)<br></p>

<p>Applications Potassium Hexadecanoate-2,2-d2 (CAS# 203805-86-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester is used in various studies of stimulators of soluble guanylate cyclase.<br>References Straub, A., et al.: Bioorg. Med. Chem. Lett., 11, 781 (2001); Mittendorf, J., et al.: ChemMedChem, 4, 853 (2009); Straub, A., et al.: Bioorg. Med. Chem., 10, 1711 (2002)<br></p>

<p>Stability Air Sensitive, Light Sensitive<br>Applications Propargyl Sulfide (cas# 13702-09-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-hydroxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester is used in the synthesis of antibacterials.<br>References Phillips, O. et al.: Exp. Opin. Ther. Pat., 19, 529 (2009);<br></p>

<p>Applications 5-Acetyl-2H-pyrazole-3-carboxylic Acid Ethyl Ester (cas# 37622-89-2) is a useful research chemical.<br></p>

<p>Applications 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic acid ethyl ester is synthesized from 5-chloro-2-oxindole (C375030), which is used in the preparation of novel GSK-3β inhibitors as anticancer agents.<br>References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);<br></p>

<p>Applications Hexacosanoic Acid Ethyl Ester is the ethyl ester derivative of Hexacosanoic Acid (H290910) and is reported to be a grape constituent.<br>References Radulovic, N., et al.: J. Essent. Oil Res., 22, 616 (2010)<br></p>

<p>Applications rac-3-Hydroxyoctadecanoic acid is a fatty acid found in foodstuffs such as vegetable oils, milk, and dairy products. rac-3-Hydroxyoctadecanoic acid is also used as a chemical marker to identify and confirm the presence of Campylobacter pylori, a gram-negative bacteria that cause duodenal ulcers in humans.<br>References Carlsson, A., et al.: Med. Sci. Res., 16, 1301 (1988); Jenske, R. &amp; Vetter, W.: Food Chem., 114, 1122 (2009); Krakowka, S., et al.: Infect. Immun., 55, 2789 (1987); Levi, S., et al.: Lancet, 333, 1167 (1989)<br></p>

<p>Applications Hexadecanoic Acid-1,2-13C2 (CAS# 86683-25-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,3,4,5-Tetrafluorobenzoylacetic Acid Ethyl Ester is a fluorinated benzoylacetate used as a synthetic reagent in the preparation of antibacterial and potential antitumor agents.<br>References Miyamoto, T. et al.: Chem. Pharmac. Bul., 36, 1321 (1988); Matsumoto, J. et al.: Qunilones, 109 (1989); Srivastava, S.K. et al.: Anti-Cancer Agents Med. Chem., 7, 685 (2007);<br></p>

<p>Applications Hexadecanoic-13,13,14,14,15,15,16,16,16-d9 Acid (CAS# 1173022-49-5) is a useful isotopically labeled research compound.<br></p>