Lípidos

<p>Stability Hygroscopic<br>Applications sn-Glycero-3-phosphocholine-d9 is an isotope labelled analog of sn-Glycero-3-phosphocholine (G598700); a phospholipid and precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in the catabolic pathway of phosphatidylcholine and is used as an nootropic.<br>References Schmidt, G., et al.: J. Biol. Chem., 161, 523 (1945); Frattola, L., et al.: Curr. Ther. Res., 49, 683 (1991); Olson, D., et al.: Science, 270, 1967 (1995)<br></p>

<p>Applications β-Sitosterol and β-sitosteryl-β-D-glucoside were isolated as analgesic constituents from the leaves of Mentha cordifolia Opiz.<br>References Tanaka, et al.: J. Biochem., 17, 483 (1933), Nigro, N.D., et al.: J. Natl. Cancer Inst., 69, 103 (1982),<br></p>

<p>Stability Hygroscopic<br>Applications 1-O-Octadecanoyl-sn-glycerol is a monoacylglycerol (MAG) based saturated fatty acid derivative.<br>References Garcia, P. et al.: J. Sep. Sci., 34, 999 (2011); Takagi, T. et al.: LIpids, 25, 398 (1990);<br></p>

<p>Applications Lauroylcholine Chloride (cas# 25234-60-0) is a compound useful in organic synthesis.<br></p>

<p>Applications rac 3-Hydroxydecanoic Acid (cas# 5561-87-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Glyceryl Tritridecanoate is used in cosmetics that stimulates the growth of hair and skin.<br>References Adachi, K., et al.: Eur. Pat. Appl. (1985), EP 129778 A2 19850102.; Jpn. Kokai Tokkyo Koho (1984), JP 59027809 A 19840214.<br></p>

<p>Applications A potential inhibitor of glutamate carboxypeptidase.<br>References Wolcott, T.G., et al.: Biochem. Biophys. Res. Commun., 57, 709 (1974), Knowles, P.F., et al.: Eur. J. Biochem., 114, 139 (1981),<br></p>

<p>Applications 1,2-Dioleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol present in vegetable oils.<br>References Mottram, H., et al.: Rapid Communications in Mass Spectrometry, 11, 1240 (1997)<br></p>

<p>Applications A glycidol fatty acid esters in edible oils. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase.<br>References Masukawa, Y. et al.: J. Am. Oil. Chem. Soc., 88, 15 (2011); Kalscheuer, R. et al.: Eur. J. Lipid. Sci. Tech., 105, 578 (2003)<br></p>

<p>Applications A phospholipid drug with antineoplastic and antiprotozoal/antifungal properties, also acts as an Akt inhibitor, and under investigation as a potential therapy against HIV infection.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, P., et al al.: Retrovirology, 5, 11 (2008), Dorio, T., et al.: Antimicrob. Agents Chemother., 52, 2855 (2008),<br></p>

<p>Applications 3-Oxo-5β-cholanoic Acid is a steroid compound with pharmacological activity. It is a bile acid. Also used in the preparation of lithocholic acid derivatives used as proteasome regulators.<br>References Iqbal, M. et al.: Steroids. 53, 413 (1989); Deyashiki, Y. et al.: Biochm. J., 282, 741 (1992);<br></p>

<p>Stability Hygroscopic<br>Applications Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).<br>References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),<br></p>

<p>Applications Lauramine Oxide, is an frequently-used amine oxide surfactant. It is strongly hydrophilic , and it forms normal micelles and normal liquid crystalline phases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kocherbitov, v., et al.: J. Molec. Struct.: Theochem., 808, 111 (2007); Kocherbitov, v., et al.: J. Phys. Chem. B., 110 (27), 13649 (2006);<br></p>

<p>Applications Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,​N'-​dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore.Also, it is derived from Arachidonic Acid &gt;97% (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.<br>References Zhao, X., et al.: J. Am. Soc. Nephrol., 15, 1244 (2004); Fang, X., et al.: J. Biol. Chem., 276, 14867 (2001); Kurosawa, T., et al.: J. Cell. Physiol., 219, 606 (2009); Mazalli, M., et al.: J. Agric. Food Chem., 57, 5028 (2009);<br></p>

<p>Applications Cetyl Stearate is a wax ester of stearic acid. Wax esters are esters between long chained fatty alcohols and fatty acids. Wax esters have significance in pharmaceutical and cosmetics applications and occur naturally in plants and animals. Stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.<br>References Wheatley, V., et al.: Biochem. J., 58, 167 (1954); Shichijo, S., et al.: Biochem. Med., 22, 256 (1979); Robosky, L., et al.: J. Lipid Res., 49, 686 (2008);<br></p>

<p>Applications Secondary metabolite of Cholesterol.<br>References Notaro, G., et al.: J. Nat. Prod., 55, 1588 (1992), Aydogmus, Z., et al.: Nat. Prod. Res., 18, 43 (2004), Mao, S., et al.: J. Nat. Prod ., 69, 1209 (2006), Shoji, T., et al.: J. Agric. Food Chem., 54, 884 (2006),<br></p>

<p>Stability Moisture and Temperature Sensitive<br>Applications (R,S)-Equol 4’-Sulfate is a sulfated metabolite of isoflavone Daidzein (D103500).<br>References Heinonen, S., et al.: Anal. Biochem., 274, 211 (1999), Setchell, K., et al.: J. Nutr., 132, 3577 (2002), Thigpen, J., et al.: Comp. Med., 53, 607 (2003), Yee, S., et al.: Food Chem. Toxicol., 46, 2713 (2008),<br></p>

<p>Applications 3-Hydroxytetradecanoic Acid is used in the preparation of liposomes coated with N-acylated molecular-weight. Also used in the synthesis of pseudomycin side-chain analogs. Also used in the study of Lipid A, a major constituent of the lipopolysaccharides, which are responsible for the toxicity of gram negative bacteria.<br>References Naberezhnykh, G. et al.: Chem. Nat. Comp., 46, 852 (2011); Chen, S. et al.: Bioorg. Med. Chem. Lett., 10, 2107 (2000); Carillo, S. et al.: Marine Drugs., 11, 184 (2013);<br></p>

<p>Applications A metabolite of Norgestimate. Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990)<br></p>

<p>Applications 1-Palmitoyl-rac-glycerol is a biomarker of metabolic responses to hepatotoxicants and carcinogens.<br>References Broadhurst, D., et al.: Metabolomics, 2, 171 (2006), Shi, J., et al.: Nat. Biotechnol., 25, 930 (2007),<br></p>

<p>Applications 1-O-Dodecylglycerol is a antibacterial agent which stimulates autolysin activity in Streptococcus faecium ATCC 9790. It is also found to be synergistic with amphotericin B against fungi.<br>References Ved, H., et al.: J. Biol. Chem., 259, 8115 (1984); Haynes, M., et al.: Antimicro. Agents Chemother., 38, 1523 (1994)<br></p>

<p>Stability Hygroscopic<br>Applications 17β-Estradiol 3-O-Sulfate is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.<br>References Li, W.J., et al.: J. Pharmacol. Exp. Therp., 323, 236 (2007); Schneider, C., et al.: Steroids., 69, 245 (2004);<br></p>

<p>Applications An epoxy fatty acid found in Pneumocystis carinii lipids.<br>References Gibson, G., et al.: Xenobiotica, 19, 1123 (1989), Pellegrini, L., et al.: Plant Physiol., 103, 509 (1993), Scheller, U., et al.: J. Biol. Chem., 273, 32528 (1998), Tijet, N., et al.: Biochem. J., 332, 583 (1998),<br></p>

<p>Applications Perhydrofarnesyl Acetone is used as a flavor and fragrance agent, it is often used in jasmine compositions.<br>References Toda, H. et al.: Dev. Food Sci., 17, 181 (1988); Maggi, F. et al.: Food Chem., 113, 216 (2009); Maggi, F. et al.: Chem. Biodiv., 8, 2057 (2011);<br></p>

<p>Applications Glyceryl Triheptadecanoate is used in cosmetics that stimulates the growth of hair and skin.<br>References Adachi, K., et al.: Eur. Pat. Appl. (1985), EP 129778 A2 19850102.; Jpn. Kokai Tokkyo Koho (1984), JP 59027809 A 19840214<br></p>

<p>Stability Light Sensitive<br>Applications A labelled vitamin precursor.<br></p>

<p>Applications Dehydroabietal is an essential oil and found in the composition of seed extractives from various Abies and Picea species.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Falsca, A., et al.: Biochem. Syst. Ecol., 69, 166-175 (2016); Wajs-Bonikowska, A., et al.: Chem. Biodivers., 13, 1194-1201 (2016)<br></p>

<p>Applications An oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>

<p>Applications Taurocholic Acid Sodium Salt Hydrate is a choleretic; Its sodium salt is a lipase accelerator. Also used as a method for the quantitation of conjugated bile acids in dried blood spots using electrospray ionization-mass spectrometry.<br>References Mills, K.A., et al.: Pedatric Res., 43, 3 (1998).<br></p>

<p>Applications A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).<br>References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),<br></p>

<p>Applications May be used as a negative control for C2 Ceramide.<br>References Bielawska, A., et al.: J. Biol. Chem., 268, 26226 (1993)<br></p>

<p>Stability Light Sensitive<br>Applications 1,2-Dioleoyl-rac-glycerol is an analog of 1,3-Dioleoylglycerol (D484210) which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.<br>References Accardo, A., et. al.: J. Mater. Chem. B., 1, 617 (2013)<br></p>

<p>Applications A biomarker of metabolic responses to hepatotoxicants and carcinogens.<br>References Broadhurst, D., et al.: Metabolomics, 2, 171 (2006), Shi, J., et al.: Nat. Biotechnol., 25, 930 (2007),<br></p>

<p>Stability Hygroscopic<br>Applications A derivative of Deoxycholic acid (DC); the bile acid nor-DC showed considerable and continuing efflux into the perfusate; this involved mostly the unchanged acid. Nor-DC was not amidated but was metabolized to mostly ester glucuronides and hydroxylated derivatives.<br>References Haslewood, G., et al.: Biochem. J., 62, 637 (1956), Clayton, L. M., et al.: J. Pharmacol. Exp. Therap., 248, 1130 (1989), Aggarwal, S., et al.: Steroids, 57, 107 (1992), Batta, A., et al.: J. Lipid Res., 33, 1403 (1992),<br></p>

<p>Applications 1-Arachidoyl-sn-glycero-3-phosphocholine is a derivative of sn-Glycero-3-phosphocholine (G598700) and can be used as a biomarker in biological studies.<br>References Tang, C.,et al.: J. Chromatogr. B, 879, 2095 (2011)<br></p>

<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 1,2-Diacetin is a derivative of Triacetin (T720850) which is used as a food additive and flavorings. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>

<p>Applications 3-Hydroxy-7,12-diketocholanoic Acid is a bile acid salt as biosurfactants.<br>References Posa, M., et al.: Steroids, 86, 16-25 (2014)<br></p>

<p>Applications 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt is useful for various surfactant applications.<br>References Mansour, H., et al.: J. Pharm. Sci., et al.: 96, 377 (2006); Dudia, A., et al.: Nano Lett., 8, 1105 (2008)<br></p>

<p>Applications Biosynthetic precursor of Sphingosine. Inhibits protein kinase C.<br>References Merrill, A.H. Jr., et al.: Biochemistry, 28, 3138 (1989)<br></p>

<p>Applications 11beta-Hydroxyprogesterone (CAS# 600-57-7) is a useful research chemical compound.<br></p>

<p>Applications 1-Decanoyl-2–lauroyl-3-chloropropanediol belongs to a group of 3-Chloropropanediol fatty acid esters, which are contaminants found in edible oils and other food sources.<br>References Z. Zelinková, et al.: Food Addi. &amp; Conta., 23:12, 1290-1298 (2006)<br></p>

<p>Stability Light Sensitive, Moisture Sensitive<br>Applications POPE is a component of E. Coli bacteria cell membrane.<br>References Tu, Y., et al.: Nature Nanotechnology, 8, 594 (2013).<br></p>

<p>Applications A major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor.<br>References Van Aller, G., et al.: Biochem. Biophys. Res. Commun., 406, 194 (2011),<br></p>

<p>Applications Sphingosine base present in crayfish and drosophila, contributing to muscle degeneration<br>References Kita, K., et al.: Eur. J. Biochem., 268, 592 (2001), Fyrst, H., et al.: J. Lipid Res., 49, 597 (2008),<br></p>

<p>Applications Amphiphilic molecule used in the synthesis of artificial cell membranes for diagnostics and therapeutics.<br>References Deckert, A.A., et al.: Langmuir, 11, 643 (1995); Charych, D., and Nagy, J.O.: Chemtech, 26(9), 24 (1996); Pan, J.J. and Charych, D.: Langmuir, 13, 1365 (1997)<br></p>

<p>Applications Laurocapram is a useful intermediate.<br></p>

<p>Applications Omega-3 fatty acid found in marine fish oils and in many phospholipids. Major structural component of excitable membranes of the retina and brain; synthesized in the liver from α-linolenic acid. Nutritional supplement.<br>References Whitcutt, J.M., et al.: Biochem. J., et al.: 67, 60 (1957), Bazan, N.G., et al.: J. Ocul. Pharmacol., 10, 591 (1994), Makrides, M., et al.: Lipids, 31, 115 (1996),<br></p>

<p>Stability Hygroscopic<br>Applications L-Propionyl carnitine has been shown to improve the heart's mechanical recovery and other metabolic parameters after ischemia-reperfusion.<br>References Reznick, A.Z., et al.: Arch. Biochem Biophys., 296, 394 (1992),<br></p>

<p>Applications Labelled Chenodiol (Chenodeoxycholic acid). A major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Fcilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol.<br>References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972), Iser, J.H., et al.: Drugs, 21, 90 (1981), Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986),<br></p>

<p>Applications (-)-8-Prenylnaringin is a prenylflavonoid, a class on non-steroidal phytoestrogen that mimicks and/or modulating endogenous estrogens via estrogen receptor binding.<br>References Miyamoto, M. et al.: Planta Med., 64, 516 (1998); Kim, H.J. et al.: Arch. Pharm. Res., 31, 1241 (2008); Zierau, O. et al.: Mol. Cell. Endocrinol., 294, 92 (2008);<br></p>

<p>Applications Taurochenodeoxycholic Acid Sodium Salt is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.<br>References Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967); Takikawa, Y. et al.: Falk Symp., 120, 249 (2001); Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (2008);<br></p>

<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>

<p>Applications (5α)-Pregnane-3,20-dione exerts neuroprotective effects in chronic autoimmune encephalomyelitis (EAE). The neuroactivity of the steroid acts as a therapeutic agent for multiple sclerosis.<br>References Caruso, D. et al.: J. Neuroendocrinol., 24, 851 (2012);<br></p>

<p>Applications Arachidonic acid (AA) is an unsaturated omega-6 fatty acid constituent of the phospholipids of cell membranes. Phospholipase A2 releases AA from the membrane phospholipids in response to inflammation.<br>References Peterson, J., et al.: J. Pediatr., 152, 788 (2008), Pichini, S., et al.: J. Pharm. Biomed. Anal., 48, 927 (2008),<br></p>

<p>Applications Phosphorylethanolamine is used in the synthesis of Sphingomyelin, a type of sphingolipid found in animal cell membrane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Myller, A.T. et al.: Appl. Surf. Sci., 257, 1616 (2010);<br></p>

<p>Applications The sodium salt hydrate form of rac-Glycerophosphoric acid (G601598), which is a useful research chemical found in bacterial communities.<br>References Wang, K.; et al.: Journal of Hazardous Materials, 360, 471 (2018).<br></p>

<p>Applications (E)-Guggulsterone acts as an α-glucosidase inhibitor also known as a hypolipidemic agent.<br>References Yang, D. et al.: J. Lipid Res., 53, 529 (2012); El-Mekkawy, S. et al.: Nat. Prod. Res., 27, 146 (2013);<br></p>

<p>Applications A triglyceride for use in making human milk replacements.<br>References Nakaya, H., et al.: Biotechnology Techniques, 12, 881 (1998), Chen, M., et al.: J. Am. Oil Chemists’ Society, 91, 525 (2004),<br></p>

<p>Applications 5α-Cholestan-3β-ol is a carbon stanol formed from biohydrogenation of Cholesterol (C432501) in the gut. Studies have also examined the conversion of 5α-Cholestan-3β-ol catalyzed by 3-β-hydroxysteroid dehydrogenase of rat liver.<br>References Serizawa, S., et al.: J. Biochem., 92, 547 (1982); Shefer, S., et al.: J. Lipid. Rsch. 7, 763 (1966);<br></p>

<p>Stability Hygroscopic<br>Applications 12β-Hydroxyisocholic Acid is a bile acid.<br>References Batta, A.K., et. al.: J. Lipid Res., 32, 977 (1991)<br></p>

<p>Applications Ursodeoxycholic Acid (U850000) derivative. 24-norUrsodeoxycholic acid is superior to Ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.<br>References Seedorf, U., et al.: J. Biol. Chem., 269, 21277 (1994), Stolowich, N., et al.: Biochemistry, 36, 1719 (1997),<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 1,2-Dioleoyl-sn-glycero-3-phosphocholine is used in the generation of micelles and liposomes.<br>References Høyrup, P., et al.: Biochim. Biophys. Acta, 1515, 133 (2001); Heberle, F., et al.: Cold Spring Harb Perspect Biol., 3, 1 (2011)<br></p>

<p>Impurity Lovastatin EP Impurity E; Lovastatin USP Related Compound A<br>Applications 4a,5-Dihydro Lovastatin (Lovastatin EP Impurity E; Lovastatin USP Related Compound A) is an impurity in Lovastatin (L472225) bulk drug.<br>References Bone, E.A., et al.: Bioorg. Med. Chem. Lett., 2, 223 (1992), Houck, A., et al.: Talanta, 40, 491 (1993),<br></p>

<p>Applications 4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>

<p>Applications 12-Hydroxylauric Acid is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum.<br>References Kubienova, L., et. al.: Biochimie, 95, 889 (2013)<br></p>

<p>Stability Light Sensitive<br>Applications (Z)-2-Chloropropane-1,3-diyl Dioleate is a lipid analagous to rac-1,3-Distearoyl-2-chloropropanediol (D493510), a new lipid in food protein hydrolyzates.<br>References Velisek, J., et al.: J. Agric. Chem., 28, 1142 (1980),<br></p>

<p>Applications n-Dodecyl β-D-Maltoside is a widely used detergent to solubilize membrane proteins.<br>References Hildebrandt, E., et. al.: BBA-Biomembranes, 1838, 2825 (2014)<br></p>

<p>Applications (4bS)-trans-8,8-Trimethyl-4b,5,6,7,8,8a,9,10-octahydro-1-isopropylphenanthren-2-ol is a naturally occurring diterpene that exhibits potent antimicrobial activity.<br>References Tian, M., et al.: Records of Natural Products, 14, 219 (2020)<br></p>

<p>Applications 3-Oxo-7a-hydroxy-5β-cholanoic Acid is a keto bile acid derivative.<br>References Bortolini, O. et al.: Tetra., 62, 4482 (2006); Bortolini, O. et al.: J. Org. Chem., 67, 5802 (2002);<br></p>

<p>Applications 1,2-Dipalmitoyl-sn-glycero-3-phosphorylethanolamine used in the synthesis ultra-thin membranes to facilitate the transfer of islets of Langerhans in the attenuation of early graft loss in avoidance of immunosuppressive therapy. Also used in the synthesis of immunoliposomes containing TAT cells for tumor cell internalization and cytotoxicity.<br>References Teramura, Y, et al.: Biomat., 34, 2683 (2013); Koren, E. et al.: J. Control. Rel., 160, 264 (2012);<br></p>

<p>Applications 5-Cholenic Acid-3β-ol is a bile acid of which the metabolism in humans results in the primary bile acids lithocholic acid and chenodeoxycholic. It is found in hgher concentrations in meconium of premature human babies when compared to full term babies.<br>References Tohma, M., et al.: Steroids, 44, 47 (1984); Kok, E., et al.: J. Biol. Chem., 256, 6155 (1981); Back, P., et al: Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 354, 83 (1973); Javitt, N., et al.: J. Biol. Chem,, 261, 12486 (1986);<br></p>

<p>Applications Δ5-Avenasterol is an analog of Stigmasterol (S686750); a plant sterol that is used as a precursor in the synthesis of progesterone.<br>References Han, P., et al.: Biotechnol. App. Biochem., 54, 105 (2009); Matsunaga, I., et al.: Anal. Biochem., 393, 222 (2009); Huang, C., et al.: Plant Physiol., 150, 1192 (2009)<br></p>