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Nucleósidos

Nucleósidos

Los nucleósidos son building blocks fundamentales de los ácidos nucleicos, compuestos por una base nitrogenada unida a una molécula de azúcar. En esta sección, puede encontrar una amplia variedad de nucleósidos esenciales para la investigación en biología molecular, bioquímica y farmacología. Estos compuestos juegan roles cruciales en la síntesis de ADN y ARN, y son vitales en varios procesos metabólicos. Los nucleósidos se utilizan para estudiar material genético, desarrollar terapias antivirales y anticancerígenas, y comprender los mecanismos celulares. En CymitQuimica, proporcionamos nucleósidos de alta calidad para apoyar sus necesidades de investigación y desarrollo, asegurando pureza y fiabilidad para sus aplicaciones experimentales.

Se han encontrado 3569 productos de "Nucleósidos"

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  • N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine


    N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine is a novel nucleoside that can be used as an antiviral agent. It is a phosphoramidite and has been shown to inhibit replication of HIV, HSV, and CMV. N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine has also been shown to be an effective inhibitor of influenza A virus in vitro. This drug inhibits viral DNA synthesis by competing with natural nucleosides for incorporation into the viral DNA chain and by inhibiting viral DNA polymerase activity.
    Fórmula:C38H36N6O5
    Pureza:Min. 95%
    Peso molecular:656.75 g/mol

    Ref: 3D-NB09434

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  • 5'-O-Methyl-D3-thymidine

    Producto controlado

    5'-O-Methyl-D3-thymidine is a synthetic nucleoside that has been modified to contain a methyl group at the 5' position. It is used in the synthesis of DNA and RNA, as well as in the preparation of phosphoramidites for oligonucleotide synthesis. This nucleoside has antiviral and anticancer properties and may be useful for treating diseases such as AIDS, hepatitis B, and leukemia. The compound can also act as an activator during polymerase chain reactions. 5'-O-Methyl-D3-thymidine is readily soluble in water and in organic solvents and is highly pure with a high yield of 99%.
    Fórmula:C11H13N2O5D3
    Pureza:Min. 95%
    Peso molecular:259.27 g/mol

    Ref: 3D-NM08850

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  • 2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite

    CAS:
    2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite is an anticancer agent that is used to treat leukemia and other cancers. It also has antiviral activity, inhibiting the viral enzyme RNA polymerase. It is a novel synthetic nucleoside that has been shown to be active against HIV in vitro. 2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite is a nucleotide analogue of guanosine and is phosphorylated by cellular enzymes to form 2'-deoxyguanosine 5' phosphate. This compound binds to DNA and inhibits replication by preventing the unwinding of DNA helixes during transcription. 2'-Deoxyguanosine 5' phosphate also blocks translation by inhibiting ribosomal protein synthesis at the initiation
    Fórmula:C44H54N7O7PS
    Pureza:Min. 95%
    Peso molecular:855.98 g/mol

    Ref: 3D-PD158794

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  • 5'-O-Benzyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite


    5'-O-Benzyl-2'-deoxy-N2-isobutyrylguanosine 3'-CE phosphoramidite is a novel antiviral nucleoside analogue that has been shown to inhibit the replication of human cytomegalovirus (HCMV) in vitro. It was also found to have anticancer activity in vivo, inhibiting DNA synthesis and cell proliferation. The compound was prepared by the reaction of 2'-deoxy-N2-isobutyrylguanosine with 5'-O-benzylphosphate using the well established phosphoramidite chemistry.
    Fórmula:C30H42N7O6P
    Pureza:Min. 95%
    Peso molecular:627.69 g/mol

    Ref: 3D-PB09111

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  • N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite

    CAS:
    N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite that is used in the synthesis of DNA. It has been shown to have antiviral activity against HIV and herpes, as well as anticancer effects. It also has high purity, being a novel synthetic nucleoside with a CAS number. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is synthesized using novel methods. The synthesis process includes activation with diphosphate, DNA, and Novel nucleosides, which are high quality and modified.
    Fórmula:C53H66N7O8PSi
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:988.19 g/mol

    Ref: 3D-PB33746

    1g
    376,00€
    2g
    574,00€
    100mg
    135,00€
    250mg
    150,00€
    500mg
    222,00€
  • N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine

    CAS:

    N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine is a versatile nucleoside building block.

    Fórmula:C38H35N5O6
    Pureza:Min. 98 Area-%
    Forma y color:White Powder
    Peso molecular:657.72 g/mol

    Ref: 3D-NB02601

    10g
    287,00€
    25g
    479,00€
    50g
    756,00€
    100g
    1.140,00€
    500g
    3.330,00€
  • 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine

    Producto controlado
    CAS:
    3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is a synthetic nucleoside analogue that inhibits the synthesis of DNA. It is a monophosphate and diphosphate analog of thymidine, which are incorporated into DNA during replication. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is an activator of RNA polymerase II and inhibits viral replication by inhibiting the function of reverse transcriptase. This drug has been shown to be effective against HIV in vitro and in vivo, as well as herpes simplex virus type 1. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine also has antitumor activity as it inhibits the growth of
    Fórmula:C16H26N3O5SiD3
    Pureza:Min. 95%
    Peso molecular:374.52 g/mol

    Ref: 3D-NA09010

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  • 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite

    CAS:
    2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is a nucleoside analogue that has been modified to contain an isobutyryl group. It is an activator of the polymerase enzyme, which helps to synthesize DNA. This product can be used in the synthesis of oligonucleotides for use as therapeutic or diagnostic agents. It has anticancer and antiviral activities, due to its ability to inhibit viral replication. This product also has high purity and quality.
    Fórmula:C44H54N7O8P
    Pureza:Min. 98 Area-%
    Forma y color:Powder
    Peso molecular:839.92 g/mol

    Ref: 3D-PD08538

    10g
    270,00€
    25g
    454,00€
    50g
    658,00€
    100g
    1.094,00€
    200g
    1.748,00€
  • N2-DMF-guanosine


    N2-DMF-guanosine is a novel antiviral agent that has been synthesized by modifying the nucleoside guanosine. It is an analog of guanosine in which the 2'-hydroxyl group has been replaced with a 2'-deoxy-2'-fluoro group, and it inhibits viral replication by inhibiting viral DNA polymerase. N2-DMF-guanosine is also used as a high quality deoxyribonucleoside monophosphate for the synthesis of ribonucleosides and nucleosides. This compound has a CAS number of 6074-37-4.

    Fórmula:C13H18N6O5
    Pureza:Min. 95%
    Peso molecular:338.32 g/mol

    Ref: 3D-ND57528

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  • 8-Azaadenosine

    CAS:
    8-Azaadenosine is a purine nucleoside that is used as a template for DNA replication. The zwitterionic form of 8-Azaadenosine is found in plants and is converted to the charged form by enzymatic reactions. 8-Azaadenosine binds to the dna template strand and acts as a hydrogen bond donor, which stabilizes the transition state of the reaction and inhibits enzyme activity. This drug has been shown to affect polymerase chain reaction (PCR) by inhibiting DNA synthesis and it has been used in cancer cell lines with resistant mutants, such as Herpes simplex virus type 1 (HSV1).
    Fórmula:C9H12N6O4
    Pureza:Min. 97 Area-%
    Forma y color:Off-White Powder
    Peso molecular:268.23 g/mol

    Ref: 3D-NA02698

    5mg
    203,00€
    10mg
    315,00€
    25mg
    444,00€
    50mg
    611,00€
    100mg
    891,00€
  • 5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine

    CAS:

    5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine is a novel nucleoside with the ability to activate ribonucleosides and phosphoramidites. It is a modified nucleoside that has been shown to have anticancer and antiviral properties. 5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine also inhibits the synthesis of viral RNA and DNA, which may result in its antiinflammatory properties. 5’-Azido-5’deoxy -2′O methyl -5′ methyl uridine has a CAS number of 187733–73–9.

    Pureza:Min. 95%

    Ref: 3D-NA163037

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  • 5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite


    5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits DNA synthesis by forming a covalent bond with the beta-subunit of DNA polymerase. It is a modified nucleoside that has been synthesized from 2'-O-methylguanosine and N2,N2-dimethoxyacetyl. 5'-O-DMT-N2-phenoxyacetyl-2'-O methylguanosine 3'-CE phosphoramidite possesses the CAS No. 16053526.
    Pureza:Min. 95%

    Ref: 3D-PD75147

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  • N4-Acetylcytidine

    CAS:
    N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.
    Fórmula:C11H15N3O6
    Pureza:Min. 95%
    Forma y color:White Powder
    Peso molecular:285.25 g/mol

    Ref: 3D-NA05753

    1kg
    4.665,00€
    50g
    485,00€
    100g
    738,00€
    250g
    1.622,00€
    500g
    2.686,00€
  • 3’,2-anhydro-2'-deoxyuridine

    CAS:
    3’,2-anhydro-2'-deoxyuridine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the ribonucleotide reductase enzyme, which catalyses the conversion of ribonucleotide diphosphates to deoxynucleotides. 3’,2-anhydro-2'-deoxyuridine also inhibits DNA synthesis by cytostatic mechanisms. This product is used as a building block in phosphoramidite synthesis and can be used for the preparation of novel nucleosides and phosphoramidites. This product was originally synthesized for use as an antiviral agent against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). It is also used as an anticancer agent in preclinical research.
    Pureza:Min. 95%

    Ref: 3D-MA162984

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  • 2'-O-tert-Butyldimethylsilyl-5'-O-MMT-uridine 3'-CE phosphoramidite


    2'-O-tert-Butyldimethylsilyl-5'-O-MMT-uridine 3'-CE phosphoramidite is a monophosphate that is synthesized by reacting 2'-O-tert-butyldimethylsilyl-5'-O-methylguanosine 3'-CE with uridine 3'-CE. This nucleoside has been shown to be an activator of the immune system and to inhibit cancer cell growth in vitro. It also inhibits the synthesis of DNA and RNA, as well as ribonucleosides and deoxyribonucleosides. The purity of this product is high, with no detectable impurities or toxic substances known to the manufacturer. It is also stable at room temperature for at least six months. This product does not contain any phosphate groups or other reactive functional groups that could interfere with downstream reactions. 2'-O-tert-Butyldimethylsily
    Fórmula:C44H59N4O8PSi
    Pureza:Min. 95%
    Peso molecular:831.04 g/mol

    Ref: 3D-PB08943

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  • Fmoc morpholino adenosine monomer


    Fmoc-morpholino adenosine monomer is a synthetic nucleoside that is used in the synthesis of oligonucleotides for use as antiviral and anticancer agents. Fmoc-morpholino adenosine monomer has been synthesized by modifying the deoxyribonucleosides, which are then phosphoramidite derivatives of ribonucleosides. This novel chemical compound has shown high activity against DNA-dependent RNA polymerase, suggesting that it may be an effective antiviral agent.

    Fórmula:C34H32ClN7O7P
    Pureza:Min. 95%
    Forma y color:Powder
    Peso molecular:717.09 g/mol

    Ref: 3D-PF180529

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  • 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine

    CAS:
    5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that belongs to the class of deoxyribonucleosides. It is a modified nucleoside with an anisoyl group at the 5' position and a benzoyl group at the 2' position. This product can be used in the synthesis of DNA, RNA, and phosphoramidites. 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine has antiviral properties and has been shown to inhibit viral replication in vitro and in vivo. It also has anticancer activities as it inhibits cell proliferation and induces apoptosis, which may be due to its ability to inhibit DNA synthesis.
    Fórmula:C24H23N3O6
    Pureza:Min. 95%
    Peso molecular:449.46 g/mol

    Ref: 3D-NA08684

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  • 5'-Azido-5'-deoxy-2'-O-methyluridine

    CAS:
    5'-Azido-5'-deoxy-2'-O-methyluridine is a nucleoside that is a modified version of 2'-deoxyuridine. It is synthesized from uridine, which is converted to 5'-azidouridine via the action of azidase. 5'-Azido-5'-deoxy-2'-O-methyluridine has antiviral activity and can be used as an activator of DNA polymerases. The monophosphate form of this compound can be phosphoramidated to give the corresponding diphosphates, which are used in DNA synthesis to produce double stranded DNA.
    Fórmula:C10H13N5O5
    Pureza:Min. 95%
    Peso molecular:283.24 g/mol

    Ref: 3D-NA163008

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  • 3-Deazaadenosine

    CAS:
    A potential role in apoptosis and cellular senescence.
    Fórmula:C11H14N4O4
    Pureza:Min. 99 Area-%
    Forma y color:Powder
    Peso molecular:266.26 g/mol

    Ref: 3D-ND04697

    1mg
    214,00€
    2mg
    359,00€
    5mg
    611,00€
    10mg
    1.051,00€
    25mg
    2.330,00€
  • 2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate


    2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate is an antiviral nucleoside with anticancer properties that is synthesized from 2'-deoxyuridine monophosphate and 5-methyluridine. This novel compound has shown antiviral activity against HIV, herpes simplex virus type 1, and herpes simplex virus type 2. It also inhibits the growth of human breast cancer cells in vitro.
    Pureza:Min. 95%

    Ref: 3D-NM71849

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