Sistema complementario
El sistema complementario es una parte crucial de la respuesta inmune, compuesto por una serie de pequeñas proteínas que mejoran la capacidad de los anticuerpos y las células fagocíticas para eliminar patógenos de un organismo. Estas proteínas trabajan juntas para opsonizar patógenos, inducir respuestas inflamatorias y lisar directamente las membranas de los patógenos, desempeñando un papel vital en la inmunidad innata y la función inmunitaria general. En CymitQuimica, ofrecemos proteínas del sistema del complemento de alta calidad para apoyar sus estudios inmunológicos e investigaciones clínicas.
Se han encontrado 172 productos de "Sistema complementario"
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MASP2 Protein, Mouse, Recombinant (His)
MASP2 Protein, Mouse, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:46.6 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-01126
5µg80,00€10µg117,00€20µg184,00€50µg363,00€100µg601,00€200µg1.084,00€500µg2.331,00€LEP(116-130)(mouse)TFA(258276-95-8 free base)
LEP(116-130)(mouse) is a synthetic leptin peptide fragment.Fórmula:C66H110F3N19O26SPureza:99.93%Forma y color:SolidPeso molecular:1674.77BCX 1470 methanesulfonate
CAS:BCX 1470 inhibits factor D & C1s better than trypsin (IC50: 96 nM & 1.6 nM, 3.4- & 200-fold).Fórmula:C15H14N2O5S3Forma y color:SolidPeso molecular:398.48Avacopan
CAS:Avacopan (CCX168) is a C5aR antagonist with selective and oral activity. Avacopan can be used to treat ANCA-related vasculitis. Cost-effective and quality-assured.Fórmula:C33H35F4N3O2Pureza:97% - 99.9%Forma y color:SolidPeso molecular:581.64Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Fórmula:C22H15NO4S2Pureza:98.49% - 98.93%Forma y color:SolidPeso molecular:421.49PMX 53 acetate(219639-75-5 free base)
CAS:PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50Fórmula:C49H69N11O9Pureza:99.91%Forma y color:SolidPeso molecular:956.16Ref: TM-TP2334
1mg105,00€5mg233,00€10mg344,00€25mg532,00€50mg735,00€100mg982,00€200mg1.333,00€1mL*10mM (DMSO)359,00€C3a 70-77 2TFA(63555-63-5(free base))
C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) is an octapeptide corresponding to the COOH terminus of C3a.Fórmula:C39H63N13O14Pureza:>99.99%Forma y color:SolidPeso molecular:1052.00ADH-503
CAS:ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.Fórmula:C27H28N2O5S2Pureza:99.03% - >99.99%Forma y color:SolidPeso molecular:524.7Ref: TM-T7776
2mg34,00€5mg49,00€10mg75,00€25mg120,00€50mg178,00€100mg259,00€200mg384,00€1mL*10mM (DMSO)52,00€Complement factor D-IN-2
CAS:Complement factor D-IN-2 is an inhibitor of Complement factor D and reduces the excessive activation of complement factor D.Fórmula:C27H24BrN7O3Pureza:99.53%Forma y color:SolidPeso molecular:574.43Ref: TM-T38332
1mg105,00€5mg241,00€10mg360,00€25mg637,00€50mg900,00€100mg1.170,00€200mg1.584,00€1mL*10mM (DMSO)299,00€Eculizumab
CAS:Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5Pureza:98.20%Forma y color:LiquidPeso molecular:145.74 kDaDanicopan
CAS:Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.Fórmula:C26H23BrFN7O3Pureza:99.94%Forma y color:SolidPeso molecular:580.41Ref: TM-T8509
1mg90,00€2mg129,00€5mg203,00€10mg310,00€25mg527,00€50mg755,00€100mg1.044,00€1mL*10mM (DMSO)260,00€JR14a
CAS:JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.Fórmula:C25H26Cl2N4O3SPureza:99.76%Forma y color:SolidPeso molecular:533.47TLQP 21 acetate
TLQP 21 acetate: Agonist for C3aR1, EC50 - 10.3 μM (mouse), 68.8 μM (human); VGF-derived with endo/extraendocrine traits.Fórmula:C109H174N40O28Pureza:99.99%Forma y color:SolidPeso molecular:2492.8Compstatin control peptide acetate
CAS:Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.Fórmula:C66H101N23O17Pureza:99.02%Forma y color:Odour SolidPeso molecular:1488.65Compstatin
CAS:Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.
Fórmula:C66H99N23O17S2Pureza:>99.99%Forma y color:SolidPeso molecular:1550.77Iptacopan hydrochloride
CAS:Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.Fórmula:C25H31ClN2O4Pureza:98.89% - 99.89%Forma y color:SolidPeso molecular:458.98Ref: TM-T9189
1mg54,00€2mg77,00€5mg114,00€10mg185,00€25mg334,00€50mg558,00€100mg928,00€200mg1.251,00€1mL*10mM (DMSO)114,00€AMY-101 acetate
AMY-101 acetate (Cp40 acetate) is a peptide, an inhibitor of C3 Complement in gingivitis and periodontitis, reduces inflammation and lowers MMP-8 and MMP-9.Fórmula:C85H121N23O20S2Pureza:98.80% - 99.98%Forma y color:SolidPeso molecular:1849.14Complement C5a Protein, Human, Recombinant
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E.Pureza:SDS-PAGE: 94.9%; SEC-HPLC: 93.5%Forma y color:Lyophilized PowderPeso molecular:8.3 kDa (predicted); 8.3 kDa (reducing conditions)Complement C3 Protein, Bovine, Recombinant (His & SUMO)
Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:39.5 kDa (predicted)Ref: TM-TMPH-00231
1mg2.350,00€5µg130,00€10µg211,00€20µg351,00€50µg520,00€100µg714,00€200µg1.027,00€500µg1.607,00€Complement C5a Protein, Pig, Recombinant (His)
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process.Forma y color:Lyophilized PowderPeso molecular:10.6 kDa (predicted)Ref: TM-TMPH-03107
5µg144,00€10µg232,00€20µg387,00€50µg573,00€100µg810,00€200µg1.142,00€500µg1.811,00€
