Carbohidratos y glucoconjugados

<p>Man-3a N-Glycan is a N-linked oligosaccharide with a trimannosyl core</p>

<p>4-Methoxyphenyl 4-O-[4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-b-D-glucopyranosyl]-3,6 -di-O-benzyl 2 deoxy 2 phthalimido b D glucopyranoside is a synthetic compound with the molecular formula C76H107N19O38. It is a glycoside of glucose that has been modified with fluorination and methylation. The product is soluble in ethanol and methanol. It has been shown to inhibit the growth of bacteria.</p>

<p>GA2-ganglioside is a ganglioside that is found in the membranes of cells. GA2-Ganglioside has been shown to inhibit the growth of tumors by binding to macrophages and T cells, which are two types of white blood cells. It has also been shown that GA2-Ganglioside can be used as a target for an antibody response against human HL-60 tumor cells. The antibody response induces cell lysis and reduces the size of the tumor. GA2-Ganglioside has also been shown to have anti-inflammatory properties, which may be due to its ability to bind to α subunits on bowel disease and infectious diseases, such as murine sarcoma virus, causing an antibody response that causes cell lysis and prevents replication of these viruses.</p>

<p>FA2B N-glycan also know as asialo, agalacto, core-fucosylated, bisected, bi-antennary N-linked glycan.</p>

<p>Glycyl-lacto-N-fucopentaose VI is a polysaccharide that is synthesized by the enzymatic activity of glycosylase, methylase, and fluorinase. It can be modified with click chemistry to introduce a fluorine atom at the C4 position of the glucose molecule. This modification can be used for the synthesis of oligosaccharides. Glycyl-lacto-N-fucopentaose VI has CAS number 108897-96-5 and is available in high purity and custom synthesis.</p>

<p>This compound is a glycosylation product of 4-methoxyphenol, 4-O-[2-O-acetyl-3,4-di-O-(2,3,4,6-tetra-O-acetyl-aD-mannopyranosyl)-6-O-benzyl -bD -mannopyrannoside]-, 3,6 -di -O -acetyl-. It has been custom synthesized for your order. This product is offered at high purity and with low background fluorescence.</p>

<p>6-Sialylgalacto-N-biosyl-serine is a custom synthesis product that has been fluorinated and modified. The material is an Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate with a CAS number of 60919-07-2. It is highly pure with a purity of &gt; 98% by HPLC analysis. The modification on the sugar molecule includes Click chemistry and Methylation. The monosaccharide sugar is the saccharide part of the molecule.</p>

<p>Lewis Y pentasaccharide-sp-biotin is a custom synthesis of an oligosaccharide with a complex carbohydrate. It can be produced by Click modification, fluorination, glycosylation, or methylation and has CAS No. 447-19-1. Lewis Y pentasaccharide-sp-biotin is a high purity product that can be used in research applications such as the study of Lewis Y antigen and its role in human immunity and cancer.</p>

<p>Used for making baked goods, soft drinks, sweets, alcoholic drinks, and infant food. It is also used to produce the sugar substitute maltitol.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-b-lactosyl azide is a custom synthesis of a carbohydrate that has been modified by the addition of acetyl groups to one end and the attachment of an azide group to the other. The synthesis of this compound has been completed in high purity and is available for purchase. This compound is a complex carbohydrate that is a sugar that can be modified by fluorination. It is also an oligosaccharide or polysaccharide with saccharide units.</p>

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.</p>

<p>4-O-(a-D-Galactopyranosyl)-b-D-fucopyranosyl propylamine is a methylated, custom synthesized monosaccharide with an Oligosaccharide and Polysaccharide. It is a Carbohydrate with Fluorination and complex carbohydrate. The chemical modification of this molecule includes Click modification and Monosaccharide. This molecule is synthesized using the methylation, Custom synthesis, Click modification, CAS No., Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate, High purity and Modification methods.</p>

<p>Sucrose is a sugar that is used as a food additive. It is the disaccharide of glucose and fructose, which are two monosaccharides. Sucrose can be synthesized by the glycosylation of glucose and fructose in an α-1,2 linkage. Sucrose can also be synthesized by the fluorination of sucrose followed by methylation with methylamine. The synthesis of sucrose starts with the reaction of acrylonitrile with formaldehyde to produce acrylonitrile trimer, which is then reacted with methanol to produce methyl 3-hydroxybutyrate. This product undergoes a series of reactions to form sucrose.</p>

<p>Found in glycoproteins including ovalbumin and human immunoglobulin M</p>

<p>a1-3 linked isomer of globotetraose</p>

<p>Chitopentaose is a pentaacetyl derivative of the sugar chitohexaose. It is an oligosaccharide that has been shown to inhibit the activity of glycosidases and lectins, which may be due to its high affinity to these enzymes. Chitopentaose has also been found to bind to insulin receptors in the human tumor cell line A-20, leading to a reduction in tumor growth. The molecule also inhibits the transcriptional regulation of genes encoding for penicillin-binding protein, mouse tumor necrosis factor, and α1-acid glycoprotein.</p>

<p>1,4-b-Galactotetraose is a galactose containing tetrasaccharide</p>

<p>Blood group antigen with spacer arm</p>

<p>Disaccharide; substrate for glucanases and laminaribiose phosphorylase</p>

<p>Produced from starch by partial hydrolysis. White hygroscopic spray-dried powder, easily digestible, either moderately sweet or almost flavorless (depending on the degree of polymerisation).</p>

<p>Isolated from ivory-nut mannan hydrolysates</p>

<p>4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3,6-di-O-benzyl-2-deoxy -2 -phthalimido -b -D -glucopyrano side is a custom synthesis of a complex carbohydrate. It has a CAS number of 140615‑82‑3 and can be found in glycosylations, carbohydrates, methylation, sugar, fluorination. It is high purity with a lot of modifications.</p>

<p>Useful CO2-philic compounds with potential uses as pharmaceutical excipients, controlled release agents, and surfactants for microemulsion systems in CO2-based processes.</p>

<p>Useful oligosaccharide-lipid conjugate for raising antibodies.</p>

<p>Non-reducing sucrose analog containing glucose and fructose; prebiotic fibre</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-mannopyranosyl)-D-glucopyranose (MDP) is a complex carbohydrate that has been modified by methylation, glycosylation, and carbocation. MDP is a saccharide that can be used in the synthesis of polysaccharides or as an intermediate for other chemical syntheses. It is also possible to modify MDP with fluorination, which may be useful in the synthesis of new types of pharmaceuticals.</p>

<p>1,4-beta-D-xylohexaose is a sugar that belongs to the group of xylooligosaccharides. It is an enzymatic inactivator that binds to the enzyme hydrolase family. Xylooligosaccharides are found in plant cell walls, where they can be used as a carbon source by termites. 1,4-beta-D-xylohexaose has been shown to be most active against neutral ph, but it is not active against acidic ph. The enzyme hydrolase family is inhibited by binding with 1,4-beta-D-xylohexaose and this prevents hydrolysis of carbohydrates, which includes glycosidic bonds.br&gt;br&gt;<br>1,4-beta-D-xylohexaose has also been shown to be beneficial for sustainable agriculture practices as it inhibits enzymes that break down xylooligosaccharides</p>

<p>GD1a (shown as sodium salt) is one of the major gangliosides in neuronal and glial membranes. It has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acids linked α2,3/α2,8 to the inner galactose residue, α2,3 to the outer galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). It interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. It plays a role in viral infection as it is a receptor for viral glycoproteins in rotavirus and paramyxovirus 1. The hexasaccharide GD1a moiety was also found on a glycoprotein that acts as a receptor for adenovirus type 37. GD1a ganglioside also interacts with botulinum neurotoxin and is crucial for its entry into cells (Kolter, 2012).</p>

<p>Lactose 6'-sulfate is a custom synthesis of a complex carbohydrate and an oligosaccharide. It is modified by methylation and glycosylation, which can be altered to create other saccharides such as galactose. Lactose 6'-sulfate has been fluorinated in the alpha position and contains a sulfate group that is attached with a click chemistry reaction. Lactose 6'-sulfate has CAS number 1015758-24-3 and is high purity.</p>

<p>2-Methyl-(4-O-b-D-glucopyranosyl)-1,2-dideoxy-a-D-glucopyrano)-[2,1-d]-2-oxazoline is a custom synthesis of a carbohydrate. It can be modified by fluorination, methylation, and monosaccharide modification. It has been synthesized from a saccharide with a molecular weight of 803. This molecule has the CAS number 91433-96-7.</p>

<p>Produced from high maltose syrup by treatment with transglucosidase</p>

<p>Ganglioside GM3 (sodium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as: lung, brain and melanomas, where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function and immune disorders (e.g., allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>Hyaluronate Rhodamine is a molecule that has been modified with a fluorescent dye. Hyaluronate Rhodamine is a complex carbohydrate that has been synthesized using monosaccharides, methylation, glycosylation, and polysaccharide synthesis. It is used in the study of molecular interactions due to its high purity and fluorescence properties.</p>

<p>GD1b (shown as sodium salt) is one of the major gangliosides in neuronal and glial membranes. It has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with it’s two sialic acids linked α2,3/α2,8 to the inner galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD1b acts as a receptor for BK virus as well as for heat-labile LTII-a toxin, produced by enteropathogenic E. coli. GD1b ganglioside also interacts with tetanus neurotoxin (TeNT) and is crucial for its entry into cells (Kolter, 2012).</p>

<p>2-Acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-D-galactopyranose (also known as galacto-N-biose, GNB and T antigen) is a β 1-3’ linked disaccharide which is found in the gastrointestinal tract as a core component of mucin. GNB has been shown to have potential to protect against glutamate excitotoxicity, a process in which nerve cells can be damaged or destroyed. GNB, along with lactose-N-biose, are found in human milk but are not metabolised by gut enzymes and are instead broken down to a digestible form by bifidobacteria found in the intestinal systems of infants in a symbiotic process.</p>

<p>4-Methoxyphenyl 4-O-[2-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3,6-di-O-(3,4,6,-tri -O acetyl 2 deoxy 2 phthalimido b D glucopyranosyl) b D mannopyranosyl] 3,6 di O benzyl 2 deoxy 2 phthalimido b D glucopyranoside (MPP) is a carbohydrate that belongs to the group of saccharides. It is an oligosaccharide sugar with a molecular weight of 1029.5 Da. This compound has been custom synthesized and is available in high purity. MPP is an ester of 4 methoxyphenol and 4 O-[2 O-(3,4,6 tri O acetyl 2 deoxy</p>

<p>Methyl protodioscin is a natural compound that has been shown to have a promising therapeutic effect on autoimmune diseases. Methyl protodioscin is derived from soybean extract and it is known to inhibit the translocation of bacteria across the gut wall, which could be due to its ability to regulate mucin gene expression. In vitro assays show that methyl protodioscin has an effect on mitochondrial membrane potential, which may be related to its anti-inflammatory properties. The effects of methyl protodioscin on mitochondrial functions were studied in C. glabrata, and it was shown that this compound can be used as a therapeutic agent for balloon injury.<br>Methyl protodioscin also inhibits the growth of Candida albicans and other fungi in vivo, suggesting that this compound might have antifungal activity.</p>

<p>Please enquire for more information about 2'',3'',4''-Tri-O-benzylfucosyllactose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>A antigen pentasaccharide Type I I, possible use in antiviral development</p>

<p>2-Azidoethyl 2-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-a-D-mannopyranoside is a carbohydrate that is a modification of the saccharide oligosaccharide. It has been synthesized by custom synthesis and has high purity, methylation, glycosylation and click modification.</p>

<p>Disialyl-TF is a monoclonal antibody that binds to the CD33 antigen on the surface of all types of cancer cells, including breast cancer cells. Disialyl-TF has been shown to reduce the growth and spread of prostate cancer cells in mice, reducing tumor size and weight. Disialyl-TF is also active against infectious diseases such as HIV, which may be due to its ability to inhibit the expression of glycan receptors. The mechanism by which it works is not yet known. Disialyl-TF has been shown to bind with high affinity to erythrocytes bearing A or B blood group antigens, making it an excellent diagnostic tool for detecting these antigens in patients with acute myeloid leukemia or other cancers.</p>

<p>GD1a oligosaccharide is the carbohydrate moiety from the disialylated glycosphingolipid GD1a of the a-series (shown in the sodium form), a major ganglioside found in neuronal and glial membranes. GD1a oligosaccharide has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acids linked α2,3/α2,8 to the inner galactose residue, α2,3 to the outer galactose residue (Ledeen, 2009). GD1a ganglioside interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GD1a ganglioside plays a role in viral infection as it is a receptor for viral glycoproteins in rotavirus and paramyxovirus 1. The hexasaccharide GD1a moiety was also found on a glycoprotein that acts as a receptor for adenovirus type 37. Additionally, GD1a ganglioside interacts with botulinum neurotoxin (BoNT) and is crucial for its entry into cells (Kolter, 2012).</p>

<p>Please enquire for more information about 2-O-β-D-Galactopyranosyl-D-galactose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Benzyl 4-O-(2,6-di-O-benzyl-b-D-galactopyranosyl)-2,3,6-tri-O-benzyl-D-glucopyranoside is a carbohydrate that belongs to the oligosaccharide class of saccharides. It is a synthetic compound with a CAS number (CAS No.: 128364-79-5) and a high purity. The carbohydrate has been synthesized by methylation, glycosylation, and click modification. Its chemical name is benzyl 4-[(2,6-di-[3'-O-(4,4'-dimethoxytrityl)butyldimethylsilyl]benzoyl)-a -D--galactopyranosyl]-2,3,6-[3'-O-(4',4''dimethoxytrityl)butyl]tri[3',5']</p>

<p>2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a saccharide that has been modified using methylation and click chemistry. It is also known as hexaacetylsucrose. This product is used in the production of glycoproteins and polysaccharides. 2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a synthetic compound that can be custom synthesized to order. It has high purity and can be ordered in a variety of purities.</p>

<p>Unusual lactose sulphate isolated from canine milk (beagle-Canis familiaris), which does not appear to have previously been isolated from milk or other natural sources. The structure was established by 2D NMR spectroscopy and mass spectrometry.</p>

<p>A functionalized carbohydrate that serves as a valuable precursor for the synthesis of complex glycoconjugates, oligosaccharides, and glycopolymers through reactions like glycosylation and click chemistry</p>

<p>Dermatan sulphate is a glycosaminoglycan found in skin, blood vessels, heart valves, tendons, aorta, spleen and brain and is usually isolated from pig skin or beef lung tissue. The disaccharide repeat unit is composed of L-iduronic acid and N-acetyl-galactosamine-4-sulphate linked β-(1,3) and β-(1,4). There are also small amounts of D-glucuronic acid.</p>