Carbohidratos y glucoconjugados

<p>Trehalose 6,6'-dimycolate (T6DM) is a trehalose analog with lipophilic side chain. T6DM causes apoptosis by blocking the toll-like receptor 4 (TLR4) and TLR2 pathways. T6DM has also been shown to reduce the inflammatory response caused by lipopolysaccharides (LPS), which are bacterial cell wall components. T6DM is a promising agent for the treatment of infectious diseases such as tuberculosis and other bacterial infections that cause inflammation.Isolated from microbial source: mycobacterium bovis</p>

<p>Methyl 2-O-allyl-4,6-O-benzylidene-3-O-(2',3',4',6'-tetra-O-acetyl-a-D-mannopyranosyl)-a-D-mannopyranoside is a sugar that is synthesized by the methylation of an oligosaccharide. This product is a white crystalline powder that has been shown to have high purity and a CAS number of 82185-93-1. It has also been modified with fluorination, which makes it resistant to degradation. Methyl 2-O-allyl 4,6 O benzylidene 3 O (2',3',4',6'-tetra - O acetyl - a D mannopyranosyl) - a D mannopyranoside is used in the synthesis of complex carbohydrates.</p>

<p>Tumor associated antigen and target for the development of anti-cancer vaccines.</p>

<p>Reductive amination of memantine with disaccharide.</p>

<p>3-O-Acetyl-1,6-anhydro-2-azido-2',3'-di-O-benzyl-4',6'-O-benzylidene-2-deoxy-b,D cellobiose is a fluorinated oligosaccharide that can be customized for a variety of applications. The sugar unit contains an acetyl group on the C1 position and an azido group at the C2 position. This compound has been subjected to click chemistry in order to form a covalent bond with 4,6'-O-benzylidene 2,3'-dideoxy b,D cellobiose.</p>

<p>4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-D-mannopyranose is a synthetic nonreducing sugar that has been modified with an acetate group at C4 and acetyl groups at C3 and C6. This compound is a white to off white crystalline solid. It is soluble in methanol and formamide. The chemical formula of the compound is CHO.</p>

<p>Gala1-2Gal-HSA is a modified, complex carbohydrate. The carbohydrate is synthesized by methylating, glycosylating and polysaccharide synthesis to produce Gala1-2Gal-HSA. It has CAS No. and can be custom synthesized with high purity. Gala1-2Gal-HSA is a monosaccharide that can be fluorinated or saccharide that can be glycosylated or methylated. Gala1-2Gal-HSA has many applications in the biomedical field such as inhibiting inflammation and preventing cancer metastasis.</p>

<p>4-Methoxyphenyl 2,4-di-O-benzoyl-3-O-benzyl-6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl)-3,5-dideoxy--D glycero--alpha--D galacto--2 nonulopyranosylonate) -beta D galactopyranoside is a carbohydrate that is custom synthesized for the modification of saccharides. It has a molecular weight of 1066.81 g/mol and is soluble in water. 4MPB is used as an intermediate for the synthesis of other carbohydrates.</p>

<p>O-(Methyl b-d-glucopyranosyluronate)-(1,3)-2-amino-2-deoxy-D-galactopyranose HCl is a synthetic monosaccharide with a molecular weight of 338.18 g/mol. It has very high purity and can be custom synthesized to suit customer needs. This product is used in glycosylation reactions and as a sugar donor in click chemistry reactions.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-acetyl-b-D-maltosyl isothiocyanate is a custom synthesis of a complex carbohydrate. It has been modified by fluorination and click chemistry. The product is available in high purity with CAS No. 81319-58-6. This product is synthesized from a monosaccharide and polysaccharide. The product is produced by methylation of the complex carbohydrate followed by modification with fluoro groups to create the desired product.</p>

<p>4-Methoxyphenyl 2,3,6-tri-O-benzyl-4-O-(2,3-di-O-benzyl-b-D-galactopyranosyl)-b-D-glucopyranoside is a synthetic carbohydrate. It is made up of a saccharide and a sugar. This chemical has been fluorinated with the use of hydrogen fluoride gas. The chemical also has methyl groups that have been added to it. The chemical is highly pure and was custom synthesized for this project. This chemical can be used in glycosylation or click chemistry.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. A number of publications have suggested that agarodecaose has properties that include: anti-microbial, antiviral, prebiotic, anti-tumoral, immunomodulatory, anti-inflammatory, glucosidase inhibitory, and hepatoprotective properties.</p>

<p>4-O-(2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-1,6-di-O-benzyl-2-deoxy--aDmuramic acid methyl ester is a synthetic carbohydrate. It is a modification of an oligosaccharide and can be used as a starting material in the synthesis of complex carbohydrates. 4ODBGMEM is synthesized by acetylation of 1,6 di O benzyl 2 deoxy a D muramic acid methyl ester with acetic anhydride and triethylamine. The compound has been shown to be effective in fluoroquinolone resistance and methicillin resistance.</p>

<p>This is a custom synthesis of a complex carbohydrate. The CAS number, polysaccharide, modification, saccharide and methylation are all listed. This is a high purity product that has been fluorinated and synthesized with a click modification. It is glycosylated and modified with methyl groups. This product is made from sugar, which is also listed.</p>

<p>Lacto-N-fucopentaose II-APD-HSA is a complex carbohydrate that has been chemically modified to include a fucose sugar. Lacto-N-fucopentaose II-APD-HSA is synthesized by the click reaction and then modified with the addition of an acetyl group. The product is then methylated and purified by HPLC. Lacto-N-fucopentaose II-APD-HSA can be used in a wide range of applications, including as a component in glycosylation reactions or as an adjuvant for fluorescence labelling.</p>

<p>2,3,2',3',4',6'-Hexa-O-acetyl-1,6-anhydro-b-D-maltose (HAP) is a custom synthesis that can be modified with fluorination, methylation, and monosaccharide. HAP is a synthetic oligosaccharide that is glycosylated and has a saccharide and sugar. HAP has the CAS No. 28868-67-9. This product can be used as an additive in food production or as a pharmaceutical agent.</p>

<p>Heparin derived dp14 saccharide ammonium salt is a synthetic glycosaminoglycan that is found in mammalian tissues and blood. This compound is synthesized from heparin, which is a Glycosylated, complex carbohydrate. The synthesis of this compound includes methylation, click modification (a type of chemical reaction), and fluorination. This product contains saccharides that are modified with sugar, oligosaccharides, or monosaccharides. It can be custom synthesized for your specific needs and is available in high purity.</p>

<p>Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a modification of the carbohydrate, which is a complex carbohydrate. It has been synthesized using Custom synthesis and Oligosaccharide. This product is highly pure, with a purity of 99%. Methyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-Dpglucopyranoside is used in the synthesis of Monosaccharide and Methylation. It can also be used in Glycosylation and Polysaccharide as well as for sugar or Fluorination.</p>

<p>Synthetic building block for oligosaccharide synthesis</p>

<p>Methyl 3-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-b-D-galactopyranoside is a custom synthesis, complex carbohydrate. It belongs to the group of oligosaccharides and polysaccharides. This product is a sugar with high purity, which can be fluorinated. The CAS number for this compound is 128396-53-2.</p>

<p>2-Acetamido-4-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is a complex carbohydrate that has been modified by fluorination, saccharide modification, and methylation. This product is synthetically produced and can be custom synthesized to meet your specifications. It has a high purity level of 99% with a monosaccharide content of 97%.</p>

<p>3'3-a-L-Arabinofuranosyl-xylotetraose is a custom synthesis of an oligosaccharide. It is a polysaccharide that is modified by methylation, glycosylation and carbamoylation. This carbohydrate has been fluorinated at the 3'3 position. The monosaccharide composition of this molecule is erythrose, arabinose and xylose.</p>

<p>The 6-deoxy-6-fluorocyclomaltoheptaose is a low molecular weight compound that has been found to have anti-amylase activity. This substance is characterized by its chromatographic techniques, which can be used to identify the chemical structure of the molecule. The 6-deoxy-6-fluorocyclomaltoheptaose has been found to consist of an amylase inhibitor and an enzyme substrate. It exhibits specificity for the catalytic site of amylase, which is located in subsite 1, and it attacks this substrate at the 6-position of glucose. This substance is not as potent as other amylase inhibitors such as d-glucose, but it does show greater specificity for amylase than other substances with similar structures.</p>

<p>Man-1 N-glycan is a synthetic oligosaccharide with a sugar chain that is terminated by an alpha-D-mannose. It is synthesized using the Click reaction and modified with fluorine. This product can be used in glycosylation, or the addition of sugar chains to proteins or lipids. Man-1 N-Glycan has high purity and can be custom synthesized to order.</p>

<p>Maltotetraose-APD-HSA is a complex carbohydrate with a high purity. Maltotetraose-APD-HSA is a synthetic oligosaccharide that has been modified by glycosylation, methylation, and fluorination. It is an alpha 1,4 linked maltotetraose that has been conjugated to HSA. Maltotetraose-APD-HSA has the CAS number 113789-04-8 and its molecular weight is 495.7 Da. Maltotetraose-APD-HSA can be found in the monosaccharides saccharide and carbohydrate categories.</p>

<p>3',4'-O-Carbonyl-6,6'-di-O-tert-butyldiphenylsilyl lactal is a synthetic oligosaccharide that has been modified with a click modification. It is comprised of 3 different monosaccharides, one saccharide, and one carbonyl group. This carbohydrate is synthesized from the natural sugar D-ribose, which is modified with an O-tert-butyldiphenylsilyl lactal. The synthesis begins with the addition of a methyl group to the sugar's primary hydroxyl group. Then the sugar is reacted with fluorine gas to form an ether bond between the sugar's primary hydroxyl and its secondary hydroxyl. The final step in the synthesis involves glycosylation of the terminal hydroxyl groups on each monosaccharide.</p>

<p>Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>Carbomethoxyethylthioethyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a glycosylide that is custom synthesized for a high purity, complex carbohydrate. It is modified with methylation and fluorination. Click modification can be done on this product to provide a more stable molecule. Carbomethoxyethylthioethyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D -glucopyranoside has CAS No. 87019-31 -6 and can be used in the synthesis of other compounds.</p>

<p>Globo-N-tetraose conjugated to HSA with acetyl-phenylenediamine spacer</p>

<p>Lacto-N-difucohexaose I-APD-KLH is a synthetic, high purity, custom synthesis carbohydrate that has been fluorinated with APD and KLH. The carbohydrate is methylated and glycosylated. Lacto-N-difucohexaose I-APD-KLH has a CAS number of 73387-87-8.</p>

<p>The maltose solution we offer is a 20% solution in water and of high purity and can be customized to meet your needs.</p>

<p>Hyaluronate rhodamine is a modified, fluorinated, methylated, and monosaccharide-containing polysaccharide. It is synthesized by the addition of a click modification to an oligosaccharide. The saccharide is used in glycosylation reactions to produce complex carbohydrates. Hyaluronate rhodamine has a molecular weight of 2500kDa.</p>

<p>Blood group B antigen trisaccharide conjugated to Biotin</p>

<p>Man-7D1 N-glycan is a synthetic, fluorinated, monosaccharide oligosaccharide that is custom synthesized for glycosylation. It has been shown to be an effective substrate for glycosylation and can be used in the synthesis of complex carbohydrates. The modification of Man-7D1 N-glycan includes fluorination, methylation, and click chemistry. This product is available in high purity and with a CAS number 83178-05-6.</p>

<p>6-a-D-Glucopyranosylmaltotriose tetradecaacetate is a synthetic carbohydrate that is used as a building block for the synthesis of complex carbohydrates. It is synthesized from maltotriose by glycosylation with 6-a-D-glucopyranose and subsequent enzymatic hydrolysis. 6-a-D-Glucopyranosylmaltotriose tetradecaacetate has been shown to be resistant to modification of its methyl groups, which makes it an ideal candidate for custom synthesis. This compound has been shown to be stable under physiological conditions, which makes it ideal for use in biomedical applications.<br>6-a-D-Glucopyranosylmaltotriose tetradecaacetate can be used in the synthesis of oligosaccharides or polysaccharides due to its high purity, which is comparable to that of dext</p>

<p>3-O-(2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl)-1,2,4,6-tetra-O-acetyl-b-D-glucopyranose is an oligosaccharide that has been modified with a click modification. This compound is a complex carbohydrate and it is synthesized from a monosaccharide. 3-O-(2,3,4,6-Tetra-O-benzyl-a-D--glucopyranosyl)-1,2,4,6-- tetra--O--acetyl--b--D--glucopyranose is used in methylation reactions.</p>

<p>Globotriaosylceramide (Gb3) is a glycolipid that has been shown to be an activator of the protein growth factor-β1. It is involved in the regulation of tumor cell proliferation and may have potential as a biomarker for cancer. Gb3 is also a drug transporter and it has been shown to have long-term efficacy in the treatment of sarcoidosis. Gb3 has been found in high concentrations in patients with HIV infection, suggesting that it may play a role in HIV replication. Studies have also shown that Gb3 may be involved in cardiac pathology and its structural analysis can help in understanding its function. Symptoms or conditions associated with elevated levels of globotriaosylceramide include: <br>• Carcinoma<br>• Cardiac disease<br>• Infectious diseases<br>• HIV infection</p>

<p>Cellotetraitol is a carbohydrate that has been isolated from the fungus Penicillium. It is a white crystalline solid that can be synthesized by hydrolyzing cellulose to cellobiose and then heating this sugar with acetic anhydride in the presence of sodium hydroxide. Cellotetraitol has two isomers, one of which is more active than the other. The most active form of cellotetraitol can be obtained as a crystalline solid at room temperature and has an optimal pH of 5. Cellotetraitol can be used for the synthesis of polyacrylamide gels, which are used to separate carbohydrates according to their size and charge.</p>

<p>Used for treatment of duodenal ulcers and gastroesophageal reflux</p>

<p>Difucosyl-para-lacto-N-hexaose I is a synthetic oligosaccharide that is used as a model for the longum subsp. of human milk oligosaccharides. The Difucosyl-para-lacto-N-hexaose I oligosaccharide was synthesized from sucrose and alpha-(1,2)-fucopyranosyl chloride, which were then reacted with para-nitrophenyl bromide (PNP). This product has been shown to inhibit the growth of respiratory pathogens in vitro by binding to c-reactive protein. It also binds to the Fc region of immunoglobulins and can act as an adjuvant for vaccines.</p>

<p>Glycyl-monosialyl,monofucosyllacto-N-neohexose I is a synthetic, fluorinated monosaccharide that has been modified with a glycosylation. This oligosaccharide is an important building block in the synthesis of complex carbohydrates. Glycyl-monosialyl,monofucosyllacto-N-neohexose I is used in the synthesis of polysaccharides and glycoproteins. It is also commonly used as a starting material for modifying other sugars with methylation or click chemistry. The CAS number for this compound is 144977-01-1. The molecular weight of this compound is 254.5 g/mol and it has a purity of 99% (HPLC).</p>

<p>2-Acetamido-3,4,6-tri-O-acetyl-b-D-galactopyranosyl bromide is an intermediate in the synthesis of 2,6-dideoxyglucose and has been used as a model for the glycosidic linkage to fluoroquinolones. The compound is a white solid that can be synthesized by reacting D-galactose with acetamidobenzene in the presence of sodium hydroxide and chloroacetone.<br>The molecular weight of this compound is 703.1 g/mol.<br>This product was developed through custom synthesis and modification. It is available at high purity.</p>

<p>Shortest chain oligosaccharide that can be classified as a maltodextrin. A component of liquid glucose (a commercial sweetener composed of glucose, maltose, maltotriose and maltotetrose).</p>

<p>Sulpho Lewisa Na is a complex carbohydrate that has been modified with fluorination and methylation. This product is custom synthesized, high purity, and has a CAS number. It is available for synthesis in various lengths of saccharides with a variety of modifications. Sulpho Lewisa Na can be used in the following applications: glycosylations, click modification, and methylation.</p>

<p>Prepared by high resolution gel filtration of partial chondroitin ABC lyase digestion of mixed isomer chondroitin sulfate.Average MW ~ 992General formula:∆UA – (GalNAc,6S or 4S - GlcA)n - GalNAc,6S or 4Swhere n is number of disaccharide units n = 1 in a tetrasaccharide (dp4) Uronic acid (∆UA) at the non-reducing ends of the oligosaccharides has a C4-C5 double bond as a result of endolytic scission. The main disaccharide repeat in the original chondroitin sulphate is GlcA – GalNAc sulphated at C-6 or C-4 of the GalNAc residue; the CSD disaccharide unit (GlcA,2S – GalNAc,6S) is a minor component comprising approx. 5% of total disaccharides.</p>

<p>Gala1-3Galb1-4Glcb-CH2CH2CH2CH2CH2CONH is a custom synthesis of an oligosaccharide. It is a complex carbohydrate that is composed of saccharides. Gala1-3Galb1-4Glcb-CH2CH2CH2CH2CH2CONH has a CAS number and can be modified with methylation, glycosylation, and click modification. This compound is a type of sugar and has been fluorinated for high purity.</p>

<p>GalNAca1-3Galb1-3GlcNAc</p>

<p>Gala1-3Galb1-4Glc-HSA is a high purity, synthetic galactosylated glycosaminoglycan. Gala1-3Galb1-4Glc-HSA is an important component of the mucin layer that coats the gastrointestinal tract and protects it from infection. It also has a role in promoting epithelial cell growth and repair. The product is available in custom synthesis or can be modified to meet specific requirements.</p>

<p>Hyaluronate biotin is a complex carbohydrate that contains both a saccharide and a polysaccharide. The saccharide is usually linked to the backbone of the polysaccharide via glycosylation.</p>

<p>The 6-O-(a-D-galactopyranosyl)-D-mannopyranose, also known as epimelibiose, is an oligosaccharide formed by linking an α-D-galactose molecule to a D-mannose molecule. It could be found in various natural products or glycoconjugates, such as glycolipids or glycoproteins. The configuration and linkage of sugars in such molecules often play a crucial role in their biological functions. 6-O-(a-D-galactopyranosyl)-D-mannopyranose can be used in research to modify polysaccharides and glycans. It has a role as a plant metabolite and a mouse metabolite.</p>