Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
Se han encontrado 8901 productos de "Derivados de Purinas y Pirimidinas"
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(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone
CAS:Producto controlado<p>Impurity Zolmitriptan USP Related Compound G<br>Applications An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase. Zolmitriptan USP Related Compound G.<br>References Ahmed, S., et al.: Bioorg. Med. Chem. Lett., 5, 2789(1995), Ahmed, S., et al.: Drug. Des. Discov., 15, 239 (1998), Brodie, A., et al.: Steroids, 65, 171 (2000),<br></p>Fórmula:C10H12N2O2Forma y color:NeatPeso molecular:192.21Tenofovir Isopropyl Ethyl Diester
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Tenofovir Disopropyl Ethyl Diester is an impurity of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Fórmula:C18H28N5O10PForma y color:NeatPeso molecular:505.423-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one Hydrochloride
CAS:Producto controlado<p>Impurity Ondansetron EP Impurity A/ Ondansetron USP Related Compound A<br>Applications 3-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one (Ondansetron EP Impurity A) is an impurity of Ondansetron (O655000), an antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackinnon, J.W.M., et al.: Eur. J. Cancer Clin. Oncol., 25, 61 (1989);<br></p>Fórmula:C16H20N2O·ClHForma y color:NeatPeso molecular:292.80Tenofovir Alafenamide-d5 (Diastereomers)
CAS:Producto controladoFórmula:C212H5H24N6O5PForma y color:NeatPeso molecular:481.50trans-Zeatin
CAS:Producto controlado<p>Applications Zeatin, purified from Zea mays, is a member of the cytokinin group of plant growth factors, the activity of which is attributed to its more stable trans form. Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. Trans-Zeatin is a potential agent for the management of skin photoaging.<br>References Murashige, T., et al.: Physiol. Plant, 15, 473 (1962), Brenneisen, P., et al.: J. Biol. Chem., 273, 5279 (1998), Choi, M., et al.: J. Dermatol. Sci., 46, 127 (2007), Bae, J., et al.: Food Chem. Toxicol., 46, 1298 (2008),<br></p>Fórmula:C10H13N5OForma y color:NeatPeso molecular:219.24Tenofovir Disoproxil Isopropoxycarbonyl
CAS:<p>Stability Hygroscopic<br>Applications Tenofovir Disoproxil derivative as antiviral and antitumor agent.<br></p>Fórmula:C23H36N5O12PForma y color:White SolidPeso molecular:605.53Pemetrexed Sodium Methyl Ester
Producto controlado<p>Applications Pemetrexed Sodium Methyl Ester is an impurity of Pemetrexed(P219550). Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Fórmula:C21H22N5NaO6Forma y color:NeatPeso molecular:463.419Acetaldehyde 2,4-Dinitrophenylhydrazone
CAS:<p>Stability Hygroscopic<br>Applications Acetaldehyde 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic alldehyde found in mainstream cigarette smoke. Dyes and metabolites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zwiener, C. et al.: Anal. Bioanal. Chem., 372, 615 (2002); Delgado, B. et al.: J. Liq. Chrom. Rel. Technol., 31, 361 (2008); Miller, J.H. et al.: J. Chrom. Sci., 48, 12 (2010);<br></p>Fórmula:C8H8N4O4Forma y color:YellowPeso molecular:224.17Phenylhydrazine
CAS:Producto controlado<p>Applications An aryl hydrazine used in the preparation of various dyes and pharmaceutical compounds. It is used in the investigation of oligosaccharides as well as the structure of photosystem II.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lattova, E. et al.: Meth. Mol. Biol., 534, 65 (2009); Anderson, L.B. et al.: J. Biol. Chem., 275, 4920 (2000);<br></p>Fórmula:C6H8N2Forma y color:Yellowish LiquidPeso molecular:108.144-(2H-1,3-benzodioxol-5-yl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:319.364013671875Ethyl-S-(+)-Clopidogrel Sulfate
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications Ethyl-(S)-(+)-Clopidogrel Sulfate is an analogue of S-(+)-Clopidogrel Hydrogen Sulfate (C587250) which is used as an antithrombotic.<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Fórmula:C17H20ClNO6S2Forma y color:White To Off-WhitePeso molecular:433.93Pirimiphos-methyl, 90%
CAS:Producto controlado<p>Applications Pirimiphos-methyl is a phosphorothioate used as an insecticide. Pirimiphos-methyl is commonly used for mosquito control as well as control of greenhouse crop pests and stored-product insects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Deighton, J. et al.: Mosq. News, 34, 163 (1974); LaHue, D.W.: J. Econ. Entomol., 68, 236 (1975); Antonious, G.F. et al.: J. Entomol. Sci., 30, 191 (1995):<br></p>Fórmula:C11H20N3O3PSPureza:90%Forma y color:ColourlessPeso molecular:305.335-cyclopropyl-N-(diaminomethylidene)-1-(quinolin-5-yl)-1H-pyrazole-4-carboxamide
CAS:Pureza:98%Peso molecular:320.3559875488281Chloromethyl Methyl Carbonate
CAS:Producto controlado<p>Applications A reagent used in the preparation of prodrugs of diacidic nonpeptide angiotensin II antagonist as well as pyrrolothiazole platelet activating factor antagonist.<br>References Aungst, B.J. et al.: Pharmac. Res., 12, 763 (1996); Davidsen, S.K. et al.: J. Med. Chem., 37, 4423 (1994);<br></p>Fórmula:C3H5ClO3Forma y color:NeatPeso molecular:124.52(R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
CAS:Producto controlado<p>Applications A acyclic phosphonate nucleotide.<br></p>Fórmula:C13H22N5O4PForma y color:White SolidPeso molecular:343.323,4-Dihydro Naratriptan Oxalate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 3,4-Dihydro Naratriptan Oxalate is the basic form of 3,4-Dihydro Naratriptan(D449205); it is an impurity of Naratriptan (N378730), It is a triptan drug and is used for the treatment of migraine headaches.<br>References Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997), Havanka, H., et al.: Clin. Ther., 22, 970 (2000),<br></p>Fórmula:C17H23N3O2S·C2H2O4Forma y color:White To Light YellowPeso molecular:333.45 + 90.031,2,3,9-Tetrahydro-9-methyl-4H-carbazol-4-one
CAS:<p>Impurity Ondansetron EP Impurity C<br>Applications 1,2,3,9-Tetrahydro-9-(methyl-d3)-4H-carbazol-4-one (Ondansetron EP Impurity C) is used in the preparation of 5-HT3 modulators useful in the treatment and prevention of 5-HT3 receptor-mediated diseases. 1,2,3,9-Tetrahydro-9-methyl-4H-carbazol-4-one is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huang, W. et al.: Zhong. Yao. Dax. Xueb., 30, 1 (1999); Kim, M. et al.: Heterocycles, 45, 2041 (1997); Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011);<br></p>Fórmula:C13H13NOForma y color:Off-WhitePeso molecular:199.252-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:259.31298828125Methotrexate
CAS:<p>Stability Hygroscopic<br>Applications A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C20H22N8O5Forma y color:Yellow To Dark YellowPeso molecular:454.446-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:277.260009765625(S)-Tenofovir Disoproxil Fumarate
CAS:Producto controlado<p>Impurity Tenofovir Disoproxil USP Related Compound A<br>Applications The S-enantiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor and used as an anti-HIV agent.Tenofovir Disoproxil USP Related Compound A.<br>References Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Fórmula:C19H30N5O10P·C4H4O4Forma y color:White SolidPeso molecular:635.529-Propenyladenine
CAS:<p>Impurity Tenofovir Disoproxil USP Related Compound B<br>Applications 9-Propenyladenine (Tenofovir Disoproxil USP Related Compound B) is an N-substituted purine and an impurity of Tenofovir (T018500). Tenofovir Disoproxil Related Compound B ((E)-9-(Prop-1-enyl)-9H-purin-6-amine).<br>References Montgomery, J.A. et al.: J. Org. Chem., 30, 3235 (1965);<br></p>Fórmula:C8H9N5Forma y color:White To Light YellowPeso molecular:175.194-Acetylamino-3-hydroxybenzoic Acid Ethyl Ester, 100 mg
CAS:<p>Impurity Oseltamivir EP Impurity D<br>Applications 4-Acetylamino-3-hydroxybenzoic Acid Ethyl Ester (Oseltamivir EP Impurity D) is an impurity in the antiviral drug Oseltamivir (O700100).<br></p>Fórmula:C11N13NO4Forma y color:NeatPeso molecular:223.23Methotrexate-Cadaverine-Biotin Conjugate
Producto controlado<p>Applications Methotrexate-Cadaverine-Biotin Conjugate is biotin labelled Methotrexate. Methotrexate (M260675) is a folic acid antagonist and it is used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C35H48N12O6SPureza:>85%Forma y color:NeatPeso molecular:764.95,6-Dihydro Uracil-13C,15N2
CAS:<p>Applications Isotope Labelled 5,6-Dihydro Uracil is a degradation product of DNA and was used in mass spectrometric studies of cellular DNA damage.<br>References Nelson, V.C., et al.: J. Label. Com. Radiopharma., 38, 713 (1996)<br></p>Fórmula:C313CH615N2O2Forma y color:Off-White To BeigePeso molecular:117.08(6-Benzhydryloxycarbonylamino-purin-9-yl)-acetic acid
CAS:Pureza:97.0%Forma y color:SolidPeso molecular:403.39801025390625Urea-15N2
CAS:Producto controlado<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986), Aebischer, P., et al.: Nat. Med., 2, 696 (1996), Prakash, S., et al.: Biotechnol. Bioeng., 46, 621 (1995),<br></p>Fórmula:CH415N2OForma y color:Off White SolidPeso molecular:62.041-Methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine 1-oxide (Imatinib Impurity)
CAS:Pureza:98%Peso molecular:509.614Tenofovir
CAS:<p>Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Fórmula:C9H14N5O4PForma y color:White To Off-WhitePeso molecular:287.21(S)-5-(1,3-Bis(tert-butoxycarbonyl)guanidino)-2-((tert-butoxycarbonyl)amino)pentanoic acid
CAS:Fórmula:C21H38N4O8Pureza:95.0%Forma y color:Liquid, No data available.Peso molecular:474.5555-Nitro Nicotinic Acid
CAS:Producto controlado<p>Applications An intermediate in the synthesis of nicotinamide with potential anticoccidial activity.<br>References Morisawa, Y. et al.: J. Med. Chem., 20, 129 (1977);<br></p>Fórmula:C6H4N2O4Forma y color:NeatPeso molecular:168.11Memantine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Fórmula:C12H21N·ClHForma y color:White To Off-WhitePeso molecular:215.763-Nitro-L-tyrosine-d3
CAS:Producto controlado<p>Applications A labelled marker for peroxynitrite. Oxidant and cytotoxic agent.<br>References Sekiguchi, M., et al.: Brain Res., 978, 228 (2003), van den Tweel, E., et al.: J. Neurobiol., 167, 64 (2005), Shirakura, T., et al.: Biol. Pharm. Bull., 28, 1658 (2005),<br></p>Fórmula:C9D3H7N2O5Forma y color:NeatPeso molecular:229.24-[6-(4-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Pureza:95.0%Peso molecular:278.31500244140625(E)-3-(2-chlorophenyl)-N-(4-(N-(pyrimidin-2-yl)sulfamoyl)phenyl)acrylamide
CAS:Pureza:98%Peso molecular:414.8599853515625N-Desmethyl Zolmitriptan
CAS:<p>Impurity Zolmitriptan USP Related Compound A<br>Stability Hygroscopic<br>Applications A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.<br>References Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 453 (2005),<br></p>Fórmula:C15H19N3O2Forma y color:NeatPeso molecular:273.33Ondansetron-d3
CAS:Producto controlado<p>Applications Ondansetron-d3 is a labeled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Fórmula:C18H16D3N3OForma y color:NeatPeso molecular:296.385-Azido Oseltamivir
CAS:Producto controlado<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Kim, C., et al.: J. Med. Chem., 41, 2451 (1998), Carbain, B., et al.: Chem. Med. Chem., 4, 335 (2009),<br></p>Fórmula:C16H26N4O4Forma y color:NeatPeso molecular:338.40Memantine Lactose Adduct
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A lactose adduct of Memantine (M218000). Intermediate in the synthesis of reducing carbohydrate Adamantane amines for use in treating Gram positive or Gram negative bacteria infections.<br>References Kustimur, et al.: Chinese Med. J., 116, 633 (2003),<br></p>Fórmula:C24H41NO10Forma y color:NeatPeso molecular:503.582-Amino-6-mercaptopurine-9-D-riboside Hydrate
CAS:<p>Stability Hygroscopic<br>Applications 2-Amino-6-mercaptopurine-9-D-riboside Hydrate (cas# 345909-25-3) is a compound useful in organic synthesis.<br></p>Fórmula:C10H13N5O4S·x(H2O)Forma y color:Light Yellow PowderPeso molecular:299.316-Mercaptopurine Monohydrate
CAS:Producto controlado<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004),<br></p>Fórmula:C5H4N4S·H2OForma y color:YellowPeso molecular:170.19
![3-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one Hydrochloride](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FD471400.webp&w=3840&q=75)
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