Derivados de Purinas y Pirimidinas
Las purinas tienen una estructura bicíclica, formada por un anillo de seis miembros fusionado con un anillo de cinco, ambos con átomos de nitrógeno en posiciones clave. Los derivados de purinas, como la adenina y la guanina, son fundamentales en la formación del ADN y ARN. Estos compuestos tienen aplicaciones terapéuticas en tratamientos contra el cáncer y enfermedades virales, al inhibir la replicación celular. Las pirimidinas, por otro lado, tienen una estructura monocíclica de seis miembros con dos átomos de nitrógeno. Sus derivados, como la citosina, timina y uracilo, también son componentes esenciales del ADN y ARN y se utilizan en la quimioterapia y tratamientos antivirales.
En CymitQuimica disponemos de derivados de purinas y pirimidinas para investigación en biología molecular, genómica y desarrollo de terapias innovadoras.
Se han encontrado 8898 productos de "Derivados de Purinas y Pirimidinas"
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DAMPA-d3
CAS:Producto controlado<p>Applications Labelled Methotrexate (M260675) analog. DAMPA is an antitumor agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Martinelli, J.E., et al.: J. Med. Chem., 22, 869 (1979);<br></p>Fórmula:C152H3H12N7O2Forma y color:Dark OrangePeso molecular:328.342-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:259.31298828125Tenofovir Alafenamide-d5 (Diastereomers)
CAS:Producto controladoFórmula:C212H5H24N6O5PForma y color:NeatPeso molecular:481.50Ref: 10-F538203
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarFormaldehyde 2,4-Dinitrophenylhydrazone
CAS:<p>Stability Shock Sensitive<br>Applications Formaldehyde 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic aldehyde found in mainstream cigarette smoke.<br>References Delgado, B. et al.: J. Liq. Chrom. Rel. Technol., 31, 361 (2008); Miller, J.H. et al.: J. Chrom. Sci., 48, 12 (2010);<br></p>Fórmula:C7H6N4O4Forma y color:NeatPeso molecular:210.15Pemetrexed Sodium Methyl Ester
Producto controlado<p>Applications Pemetrexed Sodium Methyl Ester is an impurity of Pemetrexed(P219550). Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Fórmula:C21H22N5NaO6Forma y color:NeatPeso molecular:463.4199-(2-Propenyl)adenine
CAS:Producto controlado<p>Applications 9-(2-Propenyl)adenine is an N-substituted purine used in the preparation of mesityl dihydroisoxazolyl homo-N-nucleosides.<br>References Thalassitis, A. et al.: Bioorg. Med. Chem. Lett., 19, 6433 (2009); Chiacchio, U. et al.: Tetrahedron, 60, 441 (2004)<br></p>Fórmula:C8H9N5Forma y color:NeatPeso molecular:175.19Tenofovir Disoproxil Isopropoxycarbonyl
CAS:<p>Stability Hygroscopic<br>Applications Tenofovir Disoproxil derivative as antiviral and antitumor agent.<br></p>Fórmula:C23H36N5O12PForma y color:White SolidPeso molecular:605.534-(3,4-dimethylphenyl)-6-(4-fluorophenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:293.34500122070314-(3,4-dimethylphenyl)-6-(3-methoxyphenyl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:305.3810119628906Ethyl-S-(+)-Clopidogrel Sulfate
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications Ethyl-(S)-(+)-Clopidogrel Sulfate is an analogue of S-(+)-Clopidogrel Hydrogen Sulfate (C587250) which is used as an antithrombotic.<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Fórmula:C17H20ClNO6S2Forma y color:White To Off-WhitePeso molecular:433.93N-Hydroxymethyl Sumatriptan
CAS:Producto controlado<p>Applications Hydroxymethyl Sumatriptan is an analog of Sumatriptan (S810000), a serotonin 5HT1-receptor agonist.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988), Doenicke, A., et al.: Lancet 1, 1309 (1988),<br></p>Fórmula:C15H23N3O3SForma y color:NeatPeso molecular:325.434-Chloro Kynurenine-13C2,15N
CAS:Producto controlado<p>Applications 7-Cl-kynurenic acid (7-Cl-KYNA) is a potent, selective antagonist of the NMDA/glycine receptor but penetrates poorly through the blood-brain barrier. Its prodrug, L-4-Cl-kynurenine (4-Cl-KYN), readily enters the brain from the circulation and provides antiexcitotoxic neuroprotection after systemic application.<br>References Leeson, P., et al.: J. Med. Chem., 37, 4053 (1994), Hilmas, C., et al.: J. Neurosci., 2001, 21, 7463 (2001), Palmer, G., et al.: Curr. Drug Targets, 2, 241 (2001), Wu, H., et al.: Exp. Neurol., 177, 222 (2002),<br></p>Fórmula:C813C2H11ClN15NO3Forma y color:NeatPeso molecular:245.643-Nitro-L-tyrosine-d3
CAS:Producto controlado<p>Applications A labelled marker for peroxynitrite. Oxidant and cytotoxic agent.<br>References Sekiguchi, M., et al.: Brain Res., 978, 228 (2003), van den Tweel, E., et al.: J. Neurobiol., 167, 64 (2005), Shirakura, T., et al.: Biol. Pharm. Bull., 28, 1658 (2005),<br></p>Fórmula:C9D3H7N2O5Forma y color:NeatPeso molecular:229.2Methotrexate
CAS:<p>Stability Hygroscopic<br>Applications A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C20H22N8O5Forma y color:Yellow To Dark YellowPeso molecular:454.441-Methyl Xanthine-d3
CAS:Producto controlado<p>Applications A labelled metabolite of Theophylline.<br>References ottrup, A., et al.: Pharmacol. Toxicol., 67, 340 (1990), El-Kadi, A., et al.: Drug Metab. Dispos., 28, 1112 (2000), Kim, S., et al.: J. Med. Chem., 45, 2131 ( 2002), Hansel, T., et al.: Drugs Today, 40, 55 (2004),<br></p>Fórmula:C62H3H3N4O2Forma y color:NeatPeso molecular:169.16Methotrexate-d3 Triglutamate Trifluoroacetate
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Methotrexate-d3 Triglutamate is the isotope labelled analog of Methotrexate Triglutamate (M260725); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Fórmula:C30H33D3N10O11(C2HF3O2)xForma y color:NeatPeso molecular:715.69(S)-4-(4-Aminobenzyl)-2-(1H)-oxazolidinone
CAS:Producto controlado<p>Impurity Zolmitriptan USP Related Compound G<br>Applications An intermediate of Zolmitriptan, as a novel inhibitor of the cytochrome P-450 enzyme aromatase. Zolmitriptan USP Related Compound G.<br>References Ahmed, S., et al.: Bioorg. Med. Chem. Lett., 5, 2789(1995), Ahmed, S., et al.: Drug. Des. Discov., 15, 239 (1998), Brodie, A., et al.: Steroids, 65, 171 (2000),<br></p>Fórmula:C10H12N2O2Forma y color:NeatPeso molecular:192.219-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one
CAS:Pureza:97%Peso molecular:270.2200012207031N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)-3-(trifluoromethyl)pyridine-2-sulfonamide
CAS:Pureza:98%Forma y color:SolidPeso molecular:407.32000732-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
CAS:Pureza:98.0%Forma y color:SolidPeso molecular:349.31698608398444-(5-methylthiophen-2-yl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Pureza:95.0%Peso molecular:273.36999511718754-[6-(4-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Pureza:95.0%Peso molecular:278.31500244140625Memantine Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Fórmula:C12H21N·ClHForma y color:White To Off-WhitePeso molecular:215.76Tenofovir
CAS:<p>Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Fórmula:C9H14N5O4PForma y color:White To Off-WhitePeso molecular:287.21Methotrexate-Cadaverine-Biotin Conjugate
Producto controlado<p>Applications Methotrexate-Cadaverine-Biotin Conjugate is biotin labelled Methotrexate. Methotrexate (M260675) is a folic acid antagonist and it is used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Fórmula:C35H48N12O6SPureza:>85%Forma y color:NeatPeso molecular:764.91-(2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea
CAS:Pureza:95.0%Peso molecular:396.450988769531255-(3,3-Dimethyl-ureido)-naphthalene-1-sulfonylchloride
CAS:Fórmula:C13H13ClN2O3SPureza:98%Forma y color:SolidPeso molecular:312.773-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester
CAS:<p>Impurity Allopurinol EP Impurity E / Allopurinol USP Related Compound E<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (Allopurinol EP Impurity E) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.<br>References Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975)<br></p>Fórmula:C7H9N3O3Forma y color:WhitePeso molecular:183.166-Methyl Nicotinic Acid
CAS:Producto controlado<p>Applications A degradation product of Nicotinic acid (N429250). An impurity of Nicotinic acid.<br>References Ensign, J., et al.: Biol. Chem., 239, 2285 (1964), Houghton, C., et al.: Biochem. J., 130, 879 (1972),<br></p>Fórmula:C7H7NO2Forma y color:NeatPeso molecular:137.14N-Desmethyl Zolmitriptan
CAS:<p>Impurity Zolmitriptan USP Related Compound A<br>Stability Hygroscopic<br>Applications A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.<br>References Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 453 (2005),<br></p>Fórmula:C15H19N3O2Forma y color:NeatPeso molecular:273.33Memantine Lactose Adduct
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A lactose adduct of Memantine (M218000). Intermediate in the synthesis of reducing carbohydrate Adamantane amines for use in treating Gram positive or Gram negative bacteria infections.<br>References Kustimur, et al.: Chinese Med. J., 116, 633 (2003),<br></p>Fórmula:C24H41NO10Forma y color:NeatPeso molecular:503.58N-Desacetyl 5-Azido Oseltamivir
CAS:Producto controlado<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Williams, M., et al.: Bioorg. Med. Chem. Lett., 7, 1837 (1997),<br></p>Fórmula:C14H24N4O3Forma y color:NeatPeso molecular:296.372-Amino-6-mercaptopurine-9-D-riboside Hydrate
CAS:<p>Stability Hygroscopic<br>Applications 2-Amino-6-mercaptopurine-9-D-riboside Hydrate (cas# 345909-25-3) is a compound useful in organic synthesis.<br></p>Fórmula:C10H13N5O4S·x(H2O)Forma y color:Light Yellow PowderPeso molecular:299.315-Nitro Nicotinic Acid
CAS:Producto controlado<p>Applications An intermediate in the synthesis of nicotinamide with potential anticoccidial activity.<br>References Morisawa, Y. et al.: J. Med. Chem., 20, 129 (1977);<br></p>Fórmula:C6H4N2O4Forma y color:NeatPeso molecular:168.114-Acetylamino-3-hydroxybenzoic Acid Ethyl Ester, 100 mg
CAS:<p>Impurity Oseltamivir EP Impurity D<br>Applications 4-Acetylamino-3-hydroxybenzoic Acid Ethyl Ester (Oseltamivir EP Impurity D) is an impurity in the antiviral drug Oseltamivir (O700100).<br></p>Fórmula:C11N13NO4Forma y color:NeatPeso molecular:223.23(2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:311.29800415039066-METHYL-N1-(3-METHYL-1-(6-(METHYLAMINO)PYRIMIDIN-4-YL)-1H-PYRAZOL-5-YL)BENZENE-1,3-DIAMINE
CAS:Pureza:95.0%Peso molecular:309.37701416015625Nicotinamide-d4 N-Oxide (d4 Major)
CAS:Producto controlado<p>Applications A labelled metabolite of Nicotinamide.<br>References Musfeld, C., et al.: J. Pharm. Biomed. Anal., 24, 391 (2001), Sakakibara, Y., et al.: Brain Res., 931, 68 (2002), Zielonka, J., et al.: Chem. Res. Toxicol., 19, 668 (2006), Wieczorkowska, M., et al.: Pharmacol. Rep., 59, 216 (2007),<br></p>Fórmula:C6H2D4N2O2Forma y color:NeatPeso molecular:142.15
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