Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65924 productos de "Derivados de Quinazolina y Quinolina"
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Eltenac
CAS:<p>Applications Eltenac is a nonsteroidal anti-inflammatory drug.<br>References Allen, A., et al.: Gut, 21, 249 (1980), Tobin, T., et al.: J. Vet. Pharmacol. Therap., 9, 1 (1986),<br></p>Fórmula:C12H9Cl2NO2SForma y color:NeatPeso molecular:302.18Atazanavir-d6
CAS:Producto controlado<p>Applications Atazanavir-d6 is the isotope labelled analog of Atazanavir (A790051); an azapeptide HIV protease inhibitor. Atazanavir has also been investigated as potential treatment of human immunodeficiency virus (HIV) and for anticancer purposes.<br>References Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004); Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004)<br></p>Fórmula:C38H46D6N6O7Forma y color:NeatPeso molecular:710.89Sulindac-d6
CAS:Producto controlado<p>Applications Labelled analogue of Sulindac is a non-steroidal anti-inflammatory drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bjorkman. et al.: Am. J. Med., 105, 17S (1998); Thakur, et al.: Am. J. Hypertens., 12, 925 (1999);<br></p>Fórmula:C20H11D6FO3SForma y color:NeatPeso molecular:362.45Omeprazole Sulfone N-Oxide
CAS:<p>Impurity Omeprazole EP Impurity I<br>Applications Omeprazole Sulfone N-Oxide (Omeprazole EP Impurity I) is a metabolite of Omeprazole. Impurity I.<br>References Stevens, C.M., et al.: J. Biol. Chem., 75, 182 (1950), Okamoto, S., et al.: Biochem. Biophys. Res. Commun., 101, 440 (1981)<br></p>Fórmula:C17H19N3O5SForma y color:NeatPeso molecular:377.41trans-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol(Ambroxol Impurity C)
CAS:Producto controlado<p>Impurity Ambroxol EP Impurity C Hydrochloride<br>Stability Light Sensitive<br>Applications trans-4-[[(2-Amino-3,5-dibromophenyl)methylene]amino]cyclohexanol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug and the metabolite of Bromhexine (B678600). Ambroxol EP Impurity C<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Fórmula:C13H16Br2N2OForma y color:NeatPeso molecular:376.09Acalabrutinib
CAS:Producto controlado<p>Applications Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL).<br>References Byrd; et al. (2015). "Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia."; "AstraZeneca to buy Acerta for blood cancer drug". www.rsc.org. Chemistry World - Royal Society of Chemistry. Retrieved 24 December 2015.<br></p>Fórmula:C26H23N7O2Forma y color:NeatPeso molecular:465.51(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Hydrochloride
CAS:Producto controlado<p>Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate used to prepare trans-2-arylcyclopropylamines as potent and selective dipeptidyl peptidase IV inhibitors.<br>References Tsai, T., et al.: Bioorg. Med. Chem., 17, 2388 (2009)<br></p>Fórmula:C9H9F2N·HClForma y color:Off White SolidPeso molecular:205.6322-(((6-(Difluoromethoxy)-1H-benzo[d]imidazol-2-yl)sulfonyl)methyl)-3,4-dimethoxypyridine 1-oxide
CAS:Pureza:95.0%Peso molecular:415.3699951171875Ethosuximide-d3
CAS:Producto controladoFórmula:C7H8D3NO2Forma y color:White To Light YellowPeso molecular:144.19rac-5-Bromo Naproxen
CAS:Producto controladoFórmula:C14H13BrO3Forma y color:NeatPeso molecular:309.163-(3-([1,1'-biphenyl]-4-yl)-1-phenyl-1h-pyrazol-4-yl)acrylic acid
CAS:Pureza:97%Peso molecular:366.42Celecoxib-d4
CAS:Producto controlado<p>Applications A labelled selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in the treatment of familial adenomatous polyposis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C17H10D4F3N3O2SForma y color:White To Light YellowPeso molecular:385.4Valsartan-d9 (Major)
CAS:Producto controlado<p>Applications An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C24H20D9N5O3Forma y color:Off WhitePeso molecular:444.57EPZ 6438
CAS:Producto controlado<p>Applications EPZ 6438 is a potent and selective inhibitor of EZH2.<br>References Knutson, S., et al.: Nat. Chem. Biol., 8, 890 (2012)<br></p>Fórmula:C34H44N4O4Forma y color:NeatPeso molecular:572.744-(6,7-DIMETHOXY-QUINOLIN-4-YLOXY)-PHENYLAMINE
CAS:Pureza:95.0%Forma y color:Liquid, No data available.Peso molecular:296.32598876953125Mirtazapine N-Glucuronide (Mixture of Diastereomers) Contains Unknown Inorganics >80%
CAS:Producto controlado<p>Applications Mirtazapine N-Glucuronide is a metabolite of Mirtazapine (M365000), an α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.<br>References Smith, D.A., RSC Drug Discovery Series, 1, 193 (2010); De Boer, T., et al.: Neuropharmacology, 27, 399 (1988); Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Fórmula:C23H28N3O6Pureza:>80%Forma y color:NeatPeso molecular:442.48(1R,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
CAS:Producto controlado<p>Applications An intermediate and impurity in the synthesis of Tadalafil (T004500).<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Fórmula:C20H18N2O4Forma y color:NeatPeso molecular:350.37Benzarone
CAS:Producto controlado<p>Applications Benzarone is an EYA (Eyes Absents), multifunctional protein involved in organogenesis, inhibitor which makes it a potent anticancer agent. EYA’s are over expressed in ovarian and breast cancers. As well it is involved in the synthesis of Human Uric Acid Transporter 1 inhibitors which may be used to treat kidney diseases.<br>References Tadjuidje, E. et al.: PLoS One., 7, 34806 (2012); M, Wempe, et al.: J. Med. Chem., 54, 2701 (2011);<br></p>Fórmula:C17H14O3Forma y color:NeatPeso molecular:266.29Bromperidol
CAS:<p>Applications Bromine analog of Haloperidol. Antipsychotic.<br>References Niemegeers, C.J.E., et al.: Life Sci., 24, 2201 (1979), Van Den Eeckhout, E., et al.: Eur. J. Drug Metab. Pharmacokinet., 5, 45 (1980), Vincent, S.H., et al.: J. Med. Chem., 23, 75 (1980),<br></p>Fórmula:C21H23BrFNO2Forma y color:NeatPeso molecular:420.322-De(dimethylamino)-2-vinyl Dimetindene
CAS:<p>Applications Dimetindene derivative, a histaminic H1 receptor antagonist.<br></p>Fórmula:C18H17NForma y color:Light YellowPeso molecular:247.33434-[[4-Fluoro-3-(1-piperazinylcarbonyl)phenyl]methyl]-1(2H)-phthalazinone
CAS:Producto controladoFórmula:C20H19FN4O2Forma y color:Off-WhitePeso molecular:366.39Fluazuron
CAS:Producto controlado<p>Applications A pesticide, like other BPUs it interferes with chitin synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yamada, R., et al.: Biosci., Biotechnol., Biochem., 70, 54 (2006), Kryger, U., et al.: Vet. Parasitol., 143, 380 (2007), Arakawa, T., et al.: App. Entomol. Zool., 43, 167 (2008),<br></p>Fórmula:C20H10Cl2F5N3O3Forma y color:White To Off-WhitePeso molecular:506.214-AMINO-3-CHLOROPICOLINIC ACID METHYL ESTER
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:186.60000610351562Mosapride N-Oxide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Mosapride (M731000).<br>References Chen, H., et al.: J. Pharm. Biomed. Anal., 40, 142 (2006), Pedraglio, S., et al.: J. Pharm. Biomed. Anal., 44, 665 (2007), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008), Curran, M., et al.: Drugs, 68, 981 (2008),<br></p>Fórmula:C21H25ClFN3O4Forma y color:NeatPeso molecular:437.89Defluoro-6-chloro Norfloxacin Hydrochloride
CAS:Fórmula:C16H18ClN3O3·HClForma y color:Off-WhitePeso molecular:372.25(3R)-Tetrahydrofuran-3-yl 4-Methylbenzenesulfonate
CAS:Producto controlado<p>Applications (3R)-Tetrahydrofuran-3-yl 4-Methylbenzenesulfonate is derived from (R)-(-)-3-Hydroxytetrahydrofuran (H957760), which is a versatile chemical reactant used in the synthesis of pharmaceutical agents.<br>References Hrapchak, M., et al.: J. Labelled. Comp. Radiopharm., 57, 687 (2014);<br></p>Fórmula:C11H14O4SForma y color:White To Off-WhitePeso molecular:242.29Tazarotene Sulfoxide
CAS:<p>Applications Tazarotene Sulfoxide is a derivative of Tazarotene (T010050), used for treating skin disorders.<br></p>Fórmula:C21H21NO3SForma y color:NeatPeso molecular:367.46Epicaptopril
CAS:<p>Stability Air Sensitive<br>Applications Epicaptopril is an impurity of Captopril (C175750) which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978);<br></p>Fórmula:C9H15NO3SForma y color:White To Off-WhitePeso molecular:217.28N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester
CAS:Producto controlado<p>Applications N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-N-(1-oxopentyl)-L-valine Methyl Ester is an impurity of the drug Valsartan (V095750), which is a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993); Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C25H30N2O3Forma y color:Colourless OilyPeso molecular:406.52MDV 3100-d6 (Enzalutamide-d6)
CAS:Producto controlado<p>Applications Isotope labelled MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer.<br></p>Fórmula:C21H10D6F4N4O2SForma y color:NeatPeso molecular:470.484,5-dimethyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.3699951171875Benzhydrol
CAS:<p>Impurity Diphenhydramine EP Impurity D<br>Applications Intermediate in the preparation of Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Fórmula:C13H12OForma y color:WhitePeso molecular:184.232-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-5,7-dimethoxyquinazolin-4(3H)-one
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:370.4049987792969Ref: 10-F238631
1gA consultar1mgA consultar5mgA consultar10mgA consultar100mgA consultar250mgA consultarMaropitant Citrate Salt
CAS:<p>Applications Maropitant is a neurokinin type 1 (NK-1) receptor antagonist. Recent studies show that Maropitant decreased the anesthetic requirements during visceral stimulation of the ovary and ovarian ligament in dogs.<br>References Boscan, P. et al.: Am. J. Vet. Res., 72, 1576 (2011);<br></p>Fórmula:C32H40N2O·C6H8O7Forma y color:Off White SolidPeso molecular:660.81-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine
CAS:Producto controlado<p>Applications 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is an intermediate used to prepare nonracemic γ-bicyclic heteroarylpiperazine- and heteroarylpiperidine-substituted prolinylthiazolidines as selective and orally active dipeptidylpeptidase 4 inhibitors for use as antidiabetic agents.<br>References Yoshida, T., et al.: Bioorg. Med. Chem., 20, 5705 (2012)<br></p>Fórmula:C14H18N4Forma y color:NeatPeso molecular:242.32Omeprazole Sulfide Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Omeprazole Sulfide Hydrochloride is a metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C17H19N3O2S·HClForma y color:NeatPeso molecular:329.42 + 36.46Amantadine-d15 Hydrochloride
CAS:Producto controlado<p>Applications NMDA-receptor antagonist. Antiviral; antiparkinsonian.<br>References Vernier, V.G., et al; Toxicol. Appl. Pharmacol., 15, 642 (1969), Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 12, 1 (1983),<br></p>Fórmula:C102H15H2NForma y color:NeatPeso molecular:166.34N-(4-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
CAS:Fórmula:C14H22N4OForma y color:Off-White To BeigePeso molecular:262.354-tert-Butylaminoethyl-2-methylphenol
CAS:Producto controlado<p>Impurity Salbutamol EP Impurity H<br>Applications 4-tert-Butylaminoethyl-2-methylphenol (Salbutamol EP Impurity H) is an impurity of Albuterol Sulfate (Salbutamol Sulfate) (A514500). Albuterol impurity H.<br>References Epshtein, N., et al.: Pharm. Chem. J., 38, 212 (2004), Erram, S., et al.: J. Pharm. Biomed. Anal., 40, 864 (2006),<br></p>Fórmula:C13H21NOForma y color:NeatPeso molecular:207.31Cinitapride Tartrate
CAS:<p>Applications Cinitapride Tartrate is the salt analogue of Cinitapride (C441990), a novel prokinetic benzamide-stimulating gastrointestinal motility agent and antiucer agent. It acts as an agonist of the 5-HT1 and 5-HT4 receptors and as an antagonist of the 5-HT2 receptors.<br>References Alarcon de la Lastra, C. et al.: Pharmacol, 54, 193 (1997); Robert, M. et al.: Drug Metab. Disp., 35, 1149 (2007); Alarcon de la Lastra, C. et al.: Inflam. Res., 47, 131 (1998)<br></p>Fórmula:C21H30N4O4·C4H6O6Forma y color:NeatPeso molecular:552.57Desfluoro Fluvoxketone
CAS:Producto controlado<p>Applications Desfluoro Fluvoxamine intermediate.<br></p>Fórmula:C13H16F2O2Forma y color:NeatPeso molecular:242.26S-(-)-Etomidate
CAS:Producto controlado<p>Applications Etomidate (E933300) is a hypnotic. This is a stereoisomer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Fórmula:C14H16N2O2Forma y color:NeatPeso molecular:244.29Suprofen
CAS:<p>Applications Prostaglandin biosynthesis inhibitor. Analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Niemegeers, C.J.E., et al.: Arzneim.-Forsch., 25, 1537 (1975),<br></p>Fórmula:C14H12O3SForma y color:BeigePeso molecular:260.315-Imino-N,4-bis(4-phenyl)-4,5-dihydro Riluzole
Producto controladoFórmula:C16H10F6N4O2SForma y color:NeatPeso molecular:436.336-chloro-2-(3-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.739990234375Riluzole 4-Trifluoromethoxy Isomer
CAS:Producto controlado<p>Applications Riluzole 4-Trifluoromethoxy Isomer is an impurity of Riluzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.<br>References Satyanarayana, B., et. al.: ARKIVOC, 14, 109 (2008); Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Fórmula:C8H5F3N2OSForma y color:NeatPeso molecular:234.20Benzophenone-2,3,4,5,6-d5
CAS:Producto controlado<p>Applications Benzophenone-2,3,4,5,6-d5 is derived from Benzene-d6 (B185282), which is an isotope labelled benzene, an organic compound that is a natural constituent of crude oil and one of the most basic petrochemicals.<br>References Feng, Z.X.. et al.: J. Phys. Chem. Lett. 4, 285 (2013); Pilling. M., et al.: Chem. Eng. Prog., 108, 32 (2012);<br></p>Fórmula:C13D5H5OForma y color:NeatPeso molecular:187.255-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol
CAS:Producto controlado<p>Applications 5-(1-Methyl-4-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol is a derivative of Cyproheptadine (C989200) which is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. Cyproheptadine is a 5-HT2/5-HT1C serotonin receptor antagonist; H1 histamine receptor antagonist; antipruritic.<br>References Marchei, E., et al.: J. Pharm. Biomed. Anal., 41, 1633 (2006); de-Benedictis, F., et al.: Allergy, 63, 1395 (2008); Feas, X., et al.: J. Pharm. Biomed. Anal., 50, 1044 (2009); Yu, C., et al.: Talanta, 2011, 83, 1376 (2011);<br></p>Fórmula:C21H23NOForma y color:NeatPeso molecular:305.413-Hydroxy Carbamazepine
CAS:<p>Applications A metabolite of Carbamazepine (C175840).<br>References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),<br></p>Fórmula:C15H12N2O2Forma y color:NeatPeso molecular:252.274-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde
CAS:<p>Impurity Bisoprolol EP Impurity L (Metoprolol EP Impurity C)<br>Stability Hygrscopic<br>Applications 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde (Bisoprolol EP Impurity L (Metoprolol EP Impurity C)) is a Metoprolol impurity .<br>References Baldwin, J.J. , et al.: J. Med. Chem., 29, 1065 (1986), Ravelet, C., et al.: J. Sep. Sci., 29, 1322 (2006),<br></p>Fórmula:C13H19NO3Forma y color:NeatPeso molecular:237.292-Hydroxy-6-(trifluoromethyl)nicotinamide
CAS:Fórmula:C7H5F3N2O2Pureza:≥97%Forma y color:SolidPeso molecular:206.124Propoxyphenyl Thiosildenafil
CAS:Producto controlado<p>Applications Propoxyphenyl-thiosildenafil is an analogue of Thiosildenafil (T371500). Propoxyphenyl-thiosildenafil has been used in the preparation of novel pyrazolopyrimidinethiones as PDE5 inhibitors for treating erectile dysfunction.<br></p>Fórmula:C23H32N6O3S2Forma y color:NeatPeso molecular:504.67Nisoldipine
CAS:Producto controlado<p>Applications Dihydropyridine calcium channel blocker. Antihypertensive and antianginal.<br>References Kazda, S., et al.: Arzneimittel-Forsch., 30, 2144 (1980), Pasanisi, F., et al.: Eur. J. Clin. Pharmacol., 29, 21 (1985), Lam, J., et al.: J. Am. Col. Cardiol., 6, 447 (1985)<br></p>Fórmula:C20H24N2O6Forma y color:YellowPeso molecular:388.41Bupivacaine Hydrochloride
CAS:Producto controlado<p>Applications Bupivacaine HCl (cas# 18010-40-7) is a useful research chemical.<br></p>Fórmula:C18H28N2O·ClHForma y color:NeatPeso molecular:324.89N,N'-Dicyclohexylurea
CAS:Producto controlado<p>Impurity Lomustine USP Related Compound C<br>Applications N,N'-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.<br>References Garriga, M., et al.: Chemosphere, 82, 1604 (2011)<br></p>Fórmula:C13H24N2OForma y color:Light YellowPeso molecular:224.34N1,N3-Bis(descyclohexyl) N1,N3-Bis(trans-4-Hydroxy-Cyclohexyl) Daprodustat
CAS:Producto controlado<p>Impurity Daprodustat Bishydroxylated Metabolite<br>Applications Daprodustat Metabolite is a metabolite of Daprodustat (D193368). Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O8Forma y color:NeatPeso molecular:425.43Blonanserin-d5
CAS:Producto controlado<p>Applications Labelled Blonanserin (B595850). A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic.<br>References Oka, T., et al.: Life Sci., 76, 225 (2004), Singh, A., et al.: Int. Med. J., 12, 175 (2005), Ochi, T., et al.: Bioorg. Med. Chem., Lett., 15, 1055 (2005),<br></p>Fórmula:C23H25D5FN3Forma y color:NeatPeso molecular:372.532-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol
CAS:Producto controlado<p>Applications 2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol is an impurity found in Mirtazapine (M365000). Mirtazapine Impurity B.<br></p>Fórmula:C17H21N3OForma y color:White To Off-WhitePeso molecular:283.374-Cyano-3-trifluoromethylphenylisothiocyanate
CAS:Producto controladoFórmula:C9H3F3N2SForma y color:NeatPeso molecular:228.19Trimetazidine Dihydrochloride
CAS:Producto controlado<p>Applications Coronary vasodilator. Antianginal.<br>References Fujita, et al.: Jpn. J. Pharmacol., 17, 19 (1967), Harpey, C., et al.: Cardiovasc. Drug Rev., 6, 292 (1989),<br></p>Fórmula:C14H22N2O3·2ClHForma y color:Off WhitePeso molecular:339.26Tilidine Impurity D Hydrochloride
CAS:Producto controlado<p>Applications Tilidine Impurity D Hydrochloride is an imourity of Tilidine, which is a controlled substance (opiate). Analgesic. It is used in clinical trial in comparison with Nefopam. Tilidine is one of the most widely used narcotics in Germany and Belgium.<br>References Vollmer, K.-O., et al.: Arzneim.-Forsch., 20, 990 (1970), Abeloos, J., et al.: Acta Anaesthesiol. Belg., 34, 283 (1983), Van Cauwenberge, H., et al.: Int. J. Clin. Pharmacol. Res., 12, 1 (1992),<br></p>Fórmula:C13H19NO2·ClHForma y color:NeatPeso molecular:257.761-(6-Methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid
CAS:Pureza:95.0%Forma y color:Solid, No data available.Peso molecular:313.31298828125Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Producto controlado<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Fórmula:C31H28N2OForma y color:NeatPeso molecular:444.57Sitagliptin
CAS:Producto controlado<p>Applications Sitagliptin (cas# 486460-32-6) is a useful research chemical.<br></p>Fórmula:C16H15F6N5OForma y color:Off-WhitePeso molecular:407.31(S)-9-Hydroxy Risperidone
CAS:Producto controlado<p>Applications The S-enantiomer metabolite of Risperidone, a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tiberghien, F., et al.: Anticancer Drugs, 7, 568 (1996), Kansy, M., et al.: J. Med. Chem., 41, 1007 (1998), Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Kerr, K., et al.: J. Biol. Chem., 276, 8657 (2001), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Fórmula:C23H27FN4O3Forma y color:NeatPeso molecular:426.485-Chloro-2-thiophenecarboxylic Acid
CAS:Producto controlado<p>Applications 5-Chloro-2-thiophenecarboxylic Acid is a metabolite of Rivaroxaban (R538000).<br>References Brickner, S., et al.: J. Med. Chem., 39, 673 (1996), Sato, K., et al.: Eur. J. Pharmacol., 347, 231 (1998), Chang, P., et al.: IDrugs, 7, 50 (2004), Weinz, C., et al.: Drug Metab. Dispos., 37, 1056 (2009)<br></p>Fórmula:C5H3ClO2SForma y color:NeatPeso molecular:162.59Thioacetic Acid
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications Thiacetic Acid is a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chapman, J.H. et al.: J. Chem. Soc., 579 (1950); Hoque, A., et al.: Bioorg. Med. Chem. Lett., 22, 6770 (2012)<br></p>Fórmula:C2H4OSForma y color:NeatPeso molecular:76.121-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine
CAS:Producto controlado<p>Applications 1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine is an impurity of Olanzapine (O253750), a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C17H22N4OSForma y color:NeatPeso molecular:330.452-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide
CAS:<p>Applications 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide is an ring-opened impurity of Ezetimibe (E975000).<br>References Raman, B. et al.: J. Pharmac. Biomed. Anal., 52, 73 (2010);<br></p>Fórmula:C24H23F2NO3Forma y color:WhitePeso molecular:411.44(1-Acetyl-4-(4-hydroxyphenyl)piperazine
CAS:Producto controlado<p>Applications 1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo.<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)<br></p>Fórmula:C12H16N2O2Forma y color:WhitePeso molecular:220.27N-Mesyldronedarone
CAS:Producto controlado<p>Applications N-Mesyldronedarone is an impurity of Dronedarone (D679445, HCl); a drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008); Hoy, S., et al.: Drugs, 69, 1647 (2009); Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009); Mahender, M., et al.: Org. Process Res. Dev., 18, 157 (2014)<br></p>Fórmula:C32H46N2O7S2Forma y color:NeatPeso molecular:634.854-(Benzo[d]thiazol-2-ylthio)morpholine
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:252.35000610351562Hemiacetorphan
CAS:Producto controlado<p>Applications Hemiacetorphan is an impurity of Racecadotril (R070600), which is antidiarrheal, enkephalinase inhibitor, and also capable of reducing the amount of water and electrolytes into the intestine.<br>References Cezard, J., et al.: Gastroenterol., 120, 799 (2001), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Lakshmana, P., et al.: J. Pharm. Res., 8, 39 (2009),<br></p>Fórmula:C14H17NO4SForma y color:NeatPeso molecular:295.35Tulobuterol-d9 Hydrochloride
CAS:Producto controlado<p>Applications Labelled Tulobuterol (T897250). A sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750).<br>References Kubo, S., et al.: Arzneim.-Forsch., 25, 1028 (1975), Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 44, 361 (1993), Qureshi, S., et al.: J. Exp. Med., 189, 615 (1999),<br></p>Fórmula:C122H9H9ClNO·ClHForma y color:White To Off WhitePeso molecular:273.253-Hydroxy-4-morpholino-1,2,5-thiazole
CAS:<p>Impurity Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D<br>Applications 3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol.<br>References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988),<br></p>Fórmula:C6H9N3O2SForma y color:White To Off-WhitePeso molecular:187.22β-(Cyanoimino)-1-piperidinepropanamide
CAS:Producto controlado<p>Impurity Minoxidil EP Impurity C<br>Applications β-(Cyanoimino)-1-piperidinepropanamide (Minoxidil EP Impurity C) is an impurity in the synthesis of Minoxidil (M345000), used as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Franz, T.J., et al.: Arch. Dermatol., 121, 203 (1985), Gadwood, R.C., et al.: Annu. Rep. Med. Chem., 24, 187 (1989), Hautala, T., et al.: Biochem. J., 283, 51 (1992),<br></p>Fórmula:C9H14N4OForma y color:NeatPeso molecular:194.23rac-Mephenytoin
CAS:Producto controlado<p>Applications rac-Mephenytoin is an anticonvulsant agent.<br>References Shimada, et al.: Anal. Biochem., 147, 174 (1975), Dzhagatspanyan. IA., et al.: Pharm. Chem. J., 25, 181 (1991),<br></p>Fórmula:C12H14N2O2Forma y color:White SolidPeso molecular:218.255’-Hydroxymethyl 5’-Desmethyl Meloxicam
CAS:Fórmula:C14H13N3O5S2Forma y color:NeatPeso molecular:367.40O-Pentaacetyl O-Desethyl Dapagliflozin
CAS:Fórmula:C29H31ClO11Forma y color:White To Off-WhitePeso molecular:591.003
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