Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65630 productos de "Derivados de Quinazolina y Quinolina"
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5-Hydroxyhydantoin
CAS:Producto controlado<p>Applications 5-Hydroxyhydantoin (cas# 29410-13-7) is a compound useful in organic synthesis.<br></p>Fórmula:C3H4N2O3Forma y color:WhitePeso molecular:116.08(R)-O-Desmethyl Naproxen
CAS:Producto controlado<p>Applications A metabolite of Naproxen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rettie, A., et al.: Chem. Res. Toxicol., 5, 54 (1992), Tracy, T., et al.: Biochem. Pharmacol., 52, 1305 (1996), Bonnabry, P., et al.: Eur. J. Clin. Pharmacol., 49, 305 (1996), Rao, S., et al.: J. Med. Chem., 43, 2789 (2000), Hutzler, J., et al.: Drug Metab. Dispos., 29, 1029 (2001),<br></p>Fórmula:C13H12O3Forma y color:NeatPeso molecular:216.23(S)-a,a-Diphenyl-3-pyrrolidineacetamide L-Tartrate
CAS:Producto controladoFórmula:C18H20N2O·C4H6O6Forma y color:NeatPeso molecular:430.455-(2H-1,3-benzodioxol-5-yl)-1H-pyrazole-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:232.195007324218751,3-Bis(9H-carbazol-4-yloxy)-2-propanol(Carvedilol Impurity)
CAS:Producto controlado<p>Applications A carvedilol Impurity.<br></p>Fórmula:C27H22N2O3Forma y color:NeatPeso molecular:422.482-Mercaptobenzimidazole
CAS:Producto controlado<p>Impurity Rabeprazole EP Impurity F<br>Applications An antidegradant, protecting rubber from oxidation. An intermediate in the synthesis of Rabeprazole (R070500)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Beheshti, A., et al.: J. Food Sci., 75, C135 (2010), Rohrig, U., et al.: J. Med. Chem., 53, 1172 (2010),<br></p>Fórmula:C7H6N2SForma y color:NeatPeso molecular:150.20t-Butylnorsynephrine
CAS:<p>Impurity Salbutamol EP Impurity B<br>Applications t-Butylnorsynephrine (Salbutamol EP Impurity B) is a derivative of norsynephrine, an endogenous biogenic amine that is closely related to norepinephrine, which has effects on the adrenergic and dopaminergic system. Structure and activity tudies have shown that t-Butylnorsynephrine may also exhibit effects towards β-adrenergic receptors and β-adrenergic receptor-coupled adenylate cyclase.<br>References Wong, A., et al.: Molec. Pharmacol., 31, 368 (1987); Constanzi, S., et al.: J. Comp. Chem., 33, 561, (2012);<br></p>Fórmula:C12H19NO2Forma y color:YellowPeso molecular:209.282-(4-Methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-ethanone
CAS:<p>Applications This compound is an impurity in the synthesis of Etoricoxib (E934100), a specific inhibitor of COX-2 .<br>References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)<br></p>Fórmula:C15H15NO3SForma y color:BeigePeso molecular:289.353-(4-Methyl-1H-imidazol-1-yl)-5-trifluoromethylaniline
CAS:Producto controlado<p>Applications Intermediate in the preparation of Nilotinib.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, G., et al.: Bioorg. Med. Chem. Lett., 19, 6691 (2009), Seeliger, M., et al.: Cancer Res., 69, 2384 (2009),<br></p>Fórmula:C11H10F3N3Forma y color:NeatPeso molecular:241.21Daprodustat
CAS:<p>Applications Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.<br>References Olson, E., et al.: Vasc. Med., 19, 473 (2014);<br></p>Fórmula:C19H27N3O6Forma y color:Off-WhitePeso molecular:393.43rac-Desmethyl Irinotecan Hydrochloride
CAS:Producto controlado<p>Impurity Irinotecan Related Compound C<br>Stability Hygroscopic<br>Applications Desmethyl Irinotecan Hydrochloride is an impurity in the synthesis of Irinotecan Hydrochloride (I767500), a DNA topoisomerase inhibitor.<br>References Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987), Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993);<br></p>Fórmula:C32H36N4O6·ClHForma y color:Light Yellow To YellowPeso molecular:609.11Saxagliptin
CAS:Producto controlado<p>Stability Temperature Sensitive<br>Applications Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.<br>References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),<br></p>Fórmula:C18H25N3O2Forma y color:White SolidPeso molecular:315.41Methyl 3-((phenoxycarbonyl)amino)thiophene-2-carboxylate
CAS:Pureza:95%Peso molecular:277.2900085449219O-Des(2-dimethylaminoethyl)-O-methyl Itopride
CAS:Producto controlado<p>Applications O-Des(2-dimethylaminoethyl)-O-methyl Itopride is an impurity of Itopride (I931500, HCl); a dopamine D2-receptor antagonist with anticholinesterase activity. Also gastroprokinetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwanaga, Y., et al; Jpn. J. Pharmacol., 56, 261 (1991); Mushiroda, T., et al.: Drug Metab. Dispos., 28, 1231 (2000)<br></p>Fórmula:C17H19NO4Forma y color:Off-WhitePeso molecular:301.34Nafronyl
CAS:<p>Applications Nafronyl is a selective inhibitor of serotonin receptors. Nafronyl is a vasodilator used in the treatment of intermittent claudication.<br>References Fontaine, et al.: Chim. Ther., 4, 44 (1969), Bessin, P., et al.: Eur. J. Med. Chem., 10, 291 (1975), Clyne, C.A., et al.: Br. J. Surg., 67, 347 (1980),<br></p>Fórmula:C24H33NO3Forma y color:NeatPeso molecular:383.52Indomethacin-d4
CAS:Producto controlado<p>Applications Nonsteroidal anti-inflammatory agent (NSAID).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C192H4H12ClNO4Forma y color:White To Off-WhitePeso molecular:361.816-Methoxy-2-naphthol
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications 6-Methoxy-2-naphthol is a reactant in the development of sirtuin inhibitors from pyrazolone and isoxazol-5-one cambinol analogs.<br>References Mahajan, S.S., et. al.: J. Med. Chem., 57, 3283 (2014)<br></p>Fórmula:C11H10O2Forma y color:NeatPeso molecular:174.201-epi-Darunavir
CAS:Producto controlado<p>Applications Stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.<br>References Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),<br></p>Fórmula:C27H37N3O7SForma y color:White To Off-WhitePeso molecular:547.66Selexipag
CAS:Producto controlado<p>Applications Selexipag is an orally available, highly selective, long-acting prostacyclin (IP) receptor agonist prodrug. It is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Fórmula:C26H32N4O4SForma y color:Light YellowPeso molecular:496.623-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Producto controlado<p>Impurity Risperidone EP Impurity L<br>Applications 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity L) is an intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Fórmula:C11H15ClN2OForma y color:NeatPeso molecular:226.70Ondansetron Hydrochloride Dihydrate
CAS:Fórmula:C18H19N3O·ClH·2H2OForma y color:Off-WhitePeso molecular:365.85Delamanid
CAS:<p>Stability Hygroscopic<br>Applications Delamanid is a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.<br>References Gler, M.T., et al.: New Engl. J. Med., 366, 2151 (2012); Skripconoka, V., et al.: Eur. Respir. J., 41, 1393 (2012); Diacon, A.H., et al.: Int. J. Tuberc. Lung D., 15, 949 (2011); Zhang, Q., et al.: Cell Biochem. Biophys., 67, 957 (2013)<br></p>Fórmula:C25H25F3N4O6Forma y color:NeatPeso molecular:534.484-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine
CAS:<p>Applications 4-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine is an impurity of Mirtazapine (M365000). Mirtazapine impurity E.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Wynia, G., et al.: J. Chromatography, A 773, 339 (1997),<br></p>Fórmula:C17H21N3Forma y color:NeatPeso molecular:267.373-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one Hydrochloride
CAS:Producto controlado<p>Impurity Ondansetron EP Impurity A/ Ondansetron USP Related Compound A<br>Applications 3-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one (Ondansetron EP Impurity A) is an impurity of Ondansetron (O655000), an antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mackinnon, J.W.M., et al.: Eur. J. Cancer Clin. Oncol., 25, 61 (1989);<br></p>Fórmula:C16H20N2O·ClHForma y color:NeatPeso molecular:292.803-Phenyl-4-thioxo-3,4-dihydrophthalazine-1-carboxylic acid
CAS:Pureza:98%Peso molecular:282.32000732421875Ref: 10-F771950
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarHydroxynorketamine-d6 Hydrochloride
CAS:Producto controlado<p>Applications Hydroxynorketamine-d6 Hydrochloride, is labelled Hydroxynorketamine (H949680, HCl salt), a metabolite of Ketamine (K165300, HCl salt) which is a medication used mainly for starting and maintaining anesthesia.<br>References Adams, J., et al.: Biomed. Mass Spec., 11, 527 (1981); Sass, W.C., et al.: Anal. Profiles Drug Subs., 6, 297 (1977); Reich, D.L., et al.: Can. J. Anaesth., 36, 186 (1989)<br></p>Fórmula:C12H8D6ClNO2•HClForma y color:NeatPeso molecular:282.22,6-Dichloro-N-methyl-3-nitropyridin-4-amine
CAS:Pureza:98%Forma y color:SolidPeso molecular:222.0299988[3-[[[2-(Diaminomethyleneamino)-4-thiazolyl]methyl]thio]propionyl]sulfamide Hydrochloride
CAS:Producto controlado<p>Impurity Famotidine EP Impurity C<br>Applications An intermediate in the synthesis of the metabolite of the drug Famotidine.<br>References Yanagisawa, I., et al.: J. Med. Chem., 30, 1787 (1987), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Fórmula:C8H14N6O3S3·ClHForma y color:Off-WhitePeso molecular:374.894'-O-Methylcatechin
CAS:<p>Applications A metabolite of (+)-Catechin, a major polyphenol in many fruits and vegetables.<br>References Heptinstall, S., et al.: J. Cardiovas. Pharmacol., 47, S197 (2006), Gonzalez-Manzano, S., et al.: J. Agric. Food Chem., 57, 1231 (2009), Frank, J., et al.: J. Nut., 139, 58 (2009),<br></p>Fórmula:C16H16O6Forma y color:NeatPeso molecular:304.29Cyclopentynafil
CAS:Producto controladoFórmula:C26H36N6O4SForma y color:White SolidPeso molecular:528.67Hydroxy Nefazodone Dihydrochloride
CAS:Producto controlado<p>Applications A metabolite of Nefazodone (N389100), an antidepressant.<br>References Barbhaiya, R., et al.: Eur. J. Clin. Pharmacol., 49, 221 (1995), Greene, D., et al.: Clin. Pharmacokinet., 33, 260 (1997), Kalgutkar, A., et al.: Drug Metab. Dispos., 33, 243 (2005),<br></p>Fórmula:C25H34Cl3N5O3Forma y color:NeatPeso molecular:558.93C-Desmethyl Metoprolol
CAS:Producto controlado<p>Impurity Metoprolol EP Impurity A<br>Applications C-Desmethyl Metoprolol (Metoprolol EP Impurity A) is a new byproduct detected in Metoprolol tartrate. Metoprolol impurity.<br>References Erickson, M., et al.: J. Pharma. Biomed. Analysis, 13, 567 (1995), Phinney, K., et al.: Chirality, 15, 287 (2003), Zheng, J., et al.: Anal. Chem., 78, 1535 (2006),<br></p>Fórmula:C14H23NO3Forma y color:NeatPeso molecular:253.34Dehydropinaverium Bromide
CAS:<p>Applications 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)ethoxy]ethyl]morpholinium Bromide (1:1), is the derivative of Pinaverium Bromide (P465000), which is spasmolytic agent with low incidence of anticholinergic effects. It is a drug used for functional gastrointestinal disorders.<br>References Jacquot, C., et al.: Eur. J. Med. Chem., 13, 61 (1978), Bretaudeau, J., et al.: J. Pharmacol., 11, 233 (1980), Bertrand, J., et al.: Therapie, 36, 555 (1981),<br></p>Fórmula:C26H39BrNO4·BrForma y color:NeatPeso molecular:589.40N-Nitroso-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-L-valine Methyl Ester-d8
Fórmula:C20H13D8N3O3Forma y color:Neat3-acetyl-6-fluoro-4-(4-fluorophenyl)quinolin-2(1H)-one
CAS:Pureza:95.0%Peso molecular:299.2770080566406Apixaban Dimer
CAS:Producto controlado<p>Applications Apixaban Dimer is an impurity compound of Apixaban (A726700). Apixaban is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful in the prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J. M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C40H34N10O6Forma y color:NeatPeso molecular:750.78N-(3-Chloro-2-methylphenyl)-2-hydroxynicotinamide
CAS:<p>Applications An impurity of Clonixine (L488530). Clonixine is a nonsteroidal anti-inflammatory agent used as an analgesic.<br>References Ting, P., et al.: J. Med. Chem., 33, 2697 (1990),<br></p>Fórmula:C13H11ClN2O2Forma y color:Off-White To Light YellowPeso molecular:262.69Desmethyl Levofloxacin Hydrochloride
CAS:Producto controlado<p>Applications A metabolite of Levofloxacin.<br>References Sudo, K., et al.: Xenobiotica, 16, 72 (1986), Wong, F., et al.: Drug Metab. Dispos., 18, 1103 (1990), Aminimanizani, A., et al.: J. Clin. Pharmacokinet., 40, 169 (2001), Athamna, A., et al.: J. Antimicrob. Chemother., 53, 247 (2004), Tanaka, M., et al.: J. Pharmacol., 56, 463 (2004),<br></p>Fórmula:C17H18FN3O4•HClForma y color:NeatPeso molecular:347.343646Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS:Producto controlado<p>Applications Ethyl 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Nevuluri, N. et al.: Monat. fuer Chem., 148, 1477 (2017);<br></p>Fórmula:C22H22N4O4Forma y color:NeatPeso molecular:406.43Oxaprozin-d10
CAS:Producto controlado<p>Applications Oxaprozin-d10 is the labeled analogue of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).<br>References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)<br></p>Fórmula:C18H5D10NO3Forma y color:NeatPeso molecular:303.38α,α,α’,α’-Tetramethyl-5-bromomethyl-1,3-benzenediacetonitrile
CAS:Producto controlado<p>Impurity Anastrozole EP Impurity C / Anastrozole USP Related Compound D<br>Applications α,α,α’,α’-Tetramethyl-5-bromomethyl-1,3-benzenediacetonitrile (Anastrozole EP Impurity C) is an impurity of Anastrozole (A637425) (impurity D).<br>References Ge, Z., et al.: J. Med. Chem., 13, 146 (2003),<br></p>Fórmula:C15H17BrN2Forma y color:NeatPeso molecular:305.213-Desamino-2,3-dehydro Sitagliptin
CAS:<p>Impurity Sitagliptin Tablets EP Impurity FP-D<br>Stability Hygroscopic<br>Applications 3-Desamino-2,3-dehydro Sitagliptin is an impurity of Sitagliptin (S491000)<br>References Kim, D., et al.: J. Med. Chem. 48, 141 (2005); Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005);<br></p>Fórmula:C16H12F6N4OForma y color:Colourless To Light YellowPeso molecular:390.284,6-Dimethyl-2-(methylsulfonyl)pyrimidine
CAS:Producto controlado<p>Applications 4,6-Dimethyl-2-(methylsulfonyl)pyrimidine is a reactant used in the preparation of [(dimethylpyrimidinyl)oxy]diphenyl butyric acid derivatives as endothelin receptor antagonists.<br>References Xia, J., et. al.: Bioorg. Med. Chem. Lett., 21, 3894 (2011)<br></p>Fórmula:C7H10N2O2SForma y color:Off WhitePeso molecular:186.23FOY 251
CAS:<p>Applications A metabolite of Camostat. It is a pollen protease inhibitor for prevention and control of allergy.<br>References Senochuki, K., et al.: J. Med. Chem., 38, 2521 (1995)<br></p>Fórmula:C16H15N3O4·CH4O3SForma y color:White SolidPeso molecular:409.41Vortioxetine Hydrobromide
CAS:<p>Applications Vortioxetine Hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Fórmula:C18H22N2S·BrHForma y color:Beige To Light YellowPeso molecular:379.3584-(Chloromethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
CAS:Pureza:95+%Peso molecular:429.910003662109410H-Phenothiazine
CAS:Pureza:95.0%Forma y color:Solid, Crystalline Powder or Flakes or Pellets or PowderPeso molecular:199.270004272460946-Methyl-2-pyridin-4-yl-quinoline-4-carboxylic acid
CAS:Pureza:90.0%Peso molecular:264.283996582031252-(Chloromethyl)-4-methylquinazoline
CAS:Producto controlado<p>Impurity Linagliptin 2-Chloromethyl Impurity<br>Applications 2-(Chloromethyl)-4-methylquinazoline, is a building block used for the preparation of Linagliptin (L465900), and its impurities, acting as type 2 diabetes drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Fórmula:C10H9ClN2Forma y color:NeatPeso molecular:192.644-(2-Keto-1-benzimidazolinyl)piperidine-d5 (Major)
CAS:Producto controlado<p>Applications Labelled 4-(2-Keto-1-benzimidazolinyl)piperidine is an impurity of labelled Pimozide. Pimozide impurity A.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andersson, L., et al.: J. Lipid Res., 36, 1392 (1995), Andersson, M., et al.: J. Biol. Chem., 2005, 280, 27578 (2005),<br></p>Fórmula:C12H10D5N3OForma y color:NeatPeso molecular:222.31,3-Adamantanediol
CAS:Producto controlado<p>Applications 1,3-Adamantanediol is used in the synthesis of novel dimethacrylate as possible dental monomers for dental resin mixtures.<br>References Wang, K. et al.: Mat. Sci. Eng. Mat. Biol. Appl., 32, 1141 (2012); Horino, Y. et al.: J. Mol. Catal. A. Chem.,<br></p>Fórmula:C10H16O2Forma y color:NeatPeso molecular:168.239,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-one (90%)
CAS:Producto controlado<p>Applications Intermediate in the preparation of Ketotifen.<br></p>Fórmula:C13H10OSPureza:90%Forma y color:NeatPeso molecular:214.281,4-Butane Sultone
CAS:<p>Applications 1,4-Butane Sultone is an alkylating agent with weak carcinogenic activity.<br>References Van Duuren, B.L. et al.: J. Nat. Cancer Inst., 53, 696 (1974); Druckrey, H. et al.: Zeitsch. Krebsforsch.,75, 69 (1970);<br></p>Fórmula:C4H8O3SForma y color:Colourless ViscousPeso molecular:136.174-(pyridine-3-carbonyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:290.31900024414067-Hydroxy Quetiapine-d8
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.<br>References Newton, D., et al.: Drug Metab. Dispos., 23, 154 (1995), Tanaka, E., et al.: J. Clin. Pharm. Ther., 24, 7 (1999)<br></p>Fórmula:C21H17D8N3O3SForma y color:NeatPeso molecular:407.56Flumethrin
CAS:Producto controlado<p>Applications Flumethrin is a synthetic pyrethroid insecticide used in the control of parasites, particularly ticks, on cattle, sheep, goats, horses, and dogs. Flumethrin is also used for control of mites in beehives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stendel, W. et al.: VMR Vet. Med. Rev., 2, 115 (1982); Ahrens, E.H. et al.: J. Econ. Entomol., 91, 1133 (1988); Roy, S. et al.: Ind. Vet. J., 82, 778 (2005);<br></p>Fórmula:C28H22Cl2FNO3Forma y color:Light YellowPeso molecular:510.383-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib
CAS:Producto controlado<p>Applications 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).<br>References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)<br></p>Fórmula:C22H24ClFN4O3Forma y color:NeatPeso molecular:446.90Quinoxyfen
CAS:Producto controlado<p>Applications Agricultural fungicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Corrales, M., et al.: Food Chem. Toxicol., 48, 3471 (2010), Lagunas-Allue, L., et al.: Anal. Bioanal. Chem., 398, 1509 (2010), Wong, J., et al.: J. Agric. Food Chem., 58, 5897 (2010),<br></p>Fórmula:C15H8Cl2FNOForma y color:Off-WhitePeso molecular:308.133-(4-methylphenyl)-1-phenyl-1H-pyrazole-4-carboxylic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:278.3110046386719Saxagliptin Hydrochloride
CAS:Producto controlado<p>Applications Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.<br>References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),<br></p>Fórmula:C18H25N3O2·ClHForma y color:NeatPeso molecular:351.87S-Amisulpride
CAS:Producto controlado<p>Applications S-Amisulpride is an isomer of the antipsychotic Amisulpride (A633250). S-Amisulpride has been shown to produce a maximal increase in prolactin level similar to that of the racemic form of Amisulpride.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985); Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997); Marchese, G., et. al.: Eur. J. Pharmacol., 448, 263 (2002)<br></p>Fórmula:C17H27N3O4SForma y color:NeatPeso molecular:369.483,6-Di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-1,4(2H,5H)-dione
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:300.35000610351564-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
CAS:Pureza:98%Peso molecular:361.4890136718753(4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one
CAS:Producto controlado<p>Applications AMDP3 (4-Aminophenyl)-4-methyl-4,5-dihydro-1H-pyridazin-6-one) acts as a cardiac troponin effecter, resulting in activation of cardiac muscle contractions. It’s an analogue to Levosimendan (L378000), positive inotropic agent with vasodilating activity.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995), Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996); Robertson, I. et al.: Biochem., 47, 7485 (2008);<br></p>Fórmula:C11H13N3OForma y color:Light Yellow To BrownPeso molecular:203.24N-Demethylivabradine
CAS:Producto controladoFórmula:C26H34N2O5Forma y color:Light Brown To BrownPeso molecular:454.563-[2-[4-[4-Fluoro-2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]benzolyl]piperidin-1-yl]ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS:Producto controlado<p>Impurity Risperidone EP Impurity I<br>Applications 3-[2-[4-[4-Fluoro-2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]benzolyl]piperidin-1-yl]ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity I) is a Risperidone (R525000) impurity.<br></p>Fórmula:C35H39F2N5O3Forma y color:NeatPeso molecular:615.71Indazole-3-carboxylic Acid
CAS:Producto controlado<p>Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation.<br>References Khanna P., et al.: Biochemistry, 40, 1441 (2001);<br></p>Fórmula:C8H6N2O2Forma y color:NeatPeso molecular:162.145Loxoprofen Ethyl Ester
CAS:Producto controladoFórmula:C17H22O3Forma y color:NeatPeso molecular:274.355rac threo-Dihydro Bupropion Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications rac threo-Dihydro Bupropion Hydrochloride a metabolite of the drug Bupropion (B689625), a selective inhibitor of dopamine uptake. An antidepressant of the aminoketone class; aid in smoking cessation.<br>References Soroko, F., et al.: J. Pharm. Pharmacol., 29, 769 (1977); Tucker, W.E., J. Clin. Psychiatry, 44, 60 (1983); Hsyu, P-H., et al.: J. Clin. Pharmacol., 37, 737 (1997); West, R., et al.: Expert Opin. Pharmacother., 4, 533 (2003)<br></p>Fórmula:C13H20ClNO·HClForma y color:NeatPeso molecular:241.763646Levetiracetam Carboxylic Acid
CAS:Producto controladoFórmula:C8H13NO3Forma y color:White To Off-WhitePeso molecular:171.19(Z)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid
CAS:Pureza:95.0%Forma y color:SolidPeso molecular:356.41000366210942-Bromo-4-methoxynicotinonitrile
CAS:Fórmula:C7H5BrN2OPureza:95.0%Forma y color:SolidPeso molecular:213.0345-Nitro-2-furfuraldazine
CAS:Producto controlado<p>Impurity Nitrofurazone USP Related Compound A<br>Applications 5-Nitro-2-furfuraldazine is an impurity in the synthesis of Nitrofurazone (N493880), anti-infective (topical). Antimicrobial. Nitrofurazone USP Related Compound A<br>References Morris, et al.: Cancer Res., 29, 2145 (1969), Sanderson, H., et al.: Toxicol. Lett., 144, 383 (2003),<br></p>Fórmula:C10H6N4O6Forma y color:NeatPeso molecular:278.178N-Formyl Linagliptin
Producto controlado<p>Stability Hygroscopic<br>Applications N-Formyl Linagliptin is a derivative of Linagliptin (L465900), a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Fórmula:C26H28N8O3Forma y color:NeatPeso molecular:500.55Diethyl 2-Acetamido-2-[2-(4-octylphenylethyl)malonate
CAS:Producto controlado<p>Applications An impurity found in fingolimod (F805000).<br></p>Fórmula:C25H39NO5Forma y color:NeatPeso molecular:433.58(R)-(+)-O-Desmethyl Carvedilol
CAS:Producto controlado<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α-1-blocking activity. [α]D= +18.7 (c= 0.1 methanol)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>Fórmula:C23H24N2O4Forma y color:NeatPeso molecular:392.45Methocarbamol β-D-Glucuronide Sodium Salt(Mixture of Diastereromers)
CAS:Producto controlado<p>Applications A metabolite of Methocarbamol (M225950).<br>References Thompson, R.M., et al.: Xenobiotica, 5,145 (1975),<br></p>Fórmula:C17H22NNaO11Forma y color:White To Off-WhitePeso molecular:439.351-des(piperidin-3R-amino)-1-chloro-Alogliptin
CAS:Producto controlado<p>Impurity Alogliptin 6-Chloro Impurity<br>Applications Alogliptin (A575425) intermediate.<br></p>Fórmula:C13H10ClN3O2Forma y color:NeatPeso molecular:275.69(3-(3,4-Dimethylphenyl)-1-phenyl-1H-pyrazol-4-yl)methanol
CAS:Pureza:98%Peso molecular:278.3550109863281
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