Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65541 productos de "Derivados de Quinazolina y Quinolina"
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1-((4-Fluorophenyl)carbamoyl)cyclopropanecarboxylic Acid
CAS:Producto controladoFórmula:C11H10FNO3Forma y color:Off-WhitePeso molecular:223.2Cyclopropanecarboxylic Acid
CAS:<p>Applications Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, L., et al.: Bioorg. Med. Chem. Lett., 24, 3739 (2014); Keaney, E.P., et al.: Bioorg. Med. Chem. Lett., 24, 3714 (2014)<br></p>Fórmula:C4H6O2Forma y color:NeatPeso molecular:86.09R 84852
CAS:<p>Applications R 84852 is an impurity of paliperidone (P141000), a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br>References Solanki, P.V., et. al.: ACS Sustainable Chem. Eng., 1, 243 (2013)<br></p>Fórmula:C23H28FN3O4Forma y color:NeatPeso molecular:429.48Gabapentin Related Compound E
CAS:Producto controlado<p>Impurity Gabapentin USP Related Compound E<br>Applications A Gabapentin (G117250) analogue. Gabapentin USP Related Compound E.<br>References Edafiogho, I., et al.: J. Med. Chem., 34, 387 (1991), Alexander, M., et al.: Eur. J. Med. Chem., 31, 787(1996), Obniska, J., et al.: Pharmacol. Rep., 57, 170 (2005)<br></p>Fórmula:C9H14O4Forma y color:NeatPeso molecular:186.213,7-Dihydro-3-methyl-1,7-bis(5-oxohexyl)-1H-purine-2,6-dione
CAS:Fórmula:C18H26N4O4Forma y color:NeatPeso molecular:362.42(Z)-Thiothixene
CAS:Producto controlado<p>Applications Thiothixene is a modulator of human P-glycoprotein and is frequently used a an anti-psychotic.<br>References Janowsky, D. et al.: J. Chlin. Psych., 67, 1272 (2006); Siegel, S. et al.: Eur. J. Pharm. Bioharm., 64, 287 (2006);<br></p>Fórmula:C23H29N3O2S2Forma y color:NeatPeso molecular:443.633-Pyridylmagnesium bromide, 0.25M THF
CAS:Pureza:97.0%Forma y color:LiquidPeso molecular:182.30299377441406O-Pentaacetyl O-Desethyl Dapagliflozin
CAS:Fórmula:C29H31ClO11Forma y color:White To Off-WhitePeso molecular:591.003Tadalafil-d3
CAS:Producto controlado<p>Stability Unstable in Methanol<br>Applications Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005),<br></p>Fórmula:C222H3H16N3O4Forma y color:White SolidPeso molecular:392.42β-(Cyanoimino)-1-piperidinepropanamide
CAS:Producto controlado<p>Impurity Minoxidil EP Impurity C<br>Applications β-(Cyanoimino)-1-piperidinepropanamide (Minoxidil EP Impurity C) is an impurity in the synthesis of Minoxidil (M345000), used as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Franz, T.J., et al.: Arch. Dermatol., 121, 203 (1985), Gadwood, R.C., et al.: Annu. Rep. Med. Chem., 24, 187 (1989), Hautala, T., et al.: Biochem. J., 283, 51 (1992),<br></p>Fórmula:C9H14N4OForma y color:NeatPeso molecular:194.232-Hydroxymethyl Loratadine
CAS:Producto controlado<p>Impurity Loratadine 2-Hydroxymethyl Impurity (USP)<br>Applications A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor. Loratadine 2-Hydroxymethyl Impurity (USP).<br>References Okamoto, T., et al.: Chem. Pharm. Bull ., 7, 130 (1959), Eyjolfsson, R., et al.: Pharmazie, 58, 154 (2003),<br></p>Fórmula:C23H25ClN2O3Forma y color:NeatPeso molecular:412.913-Hydroxy-4-morpholino-1,2,5-thiazole
CAS:<p>Impurity Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D<br>Applications 3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol.<br>References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988),<br></p>Fórmula:C6H9N3O2SForma y color:White To Off-WhitePeso molecular:187.22Tulobuterol-d9 Hydrochloride
CAS:Producto controlado<p>Applications Labelled Tulobuterol (T897250). A sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750).<br>References Kubo, S., et al.: Arzneim.-Forsch., 25, 1028 (1975), Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 44, 361 (1993), Qureshi, S., et al.: J. Exp. Med., 189, 615 (1999),<br></p>Fórmula:C122H9H9ClNO·ClHForma y color:White To Off WhitePeso molecular:273.25Hemiacetorphan
CAS:Producto controlado<p>Applications Hemiacetorphan is an impurity of Racecadotril (R070600), which is antidiarrheal, enkephalinase inhibitor, and also capable of reducing the amount of water and electrolytes into the intestine.<br>References Cezard, J., et al.: Gastroenterol., 120, 799 (2001), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Lakshmana, P., et al.: J. Pharm. Res., 8, 39 (2009),<br></p>Fórmula:C14H17NO4SForma y color:NeatPeso molecular:295.35Topiramate Dimer Derivative
Producto controlado<p>Applications Topiramate Dimer Derivative is an impurity of Topiramate (T540250). Topiramate is an anticonvulsant.<br>References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)<br></p>Fórmula:C25H40N2O14SForma y color:NeatPeso molecular:624.655Olanzapine LIP 1 Acetyl
CAS:<p>Applications Olanazpine LIP 1 Acetyl is an Olanazpine impurity. Olanazpine is an antipsychotic medicine.<br>References Perera, V., et al.: Br. J. Clin. Pharmacol., 78, 800 (2014); Pratt, N., et al.: Pharmacoepidemiol. Drug Saf., 22, 915 (2013)<br></p>Fórmula:C18H20N4OSForma y color:YellowPeso molecular:340.44rac Viloxazine-d5 Hydrochloride
CAS:Producto controlado<p>Applications Labelled Viloxazine (V312440). Antidepressant.<br>References Howe, R., et al.: J. Med. Chem., 19, 1074 (1976), Pinder, R.M., et al.: Drugs, 13, 401 (1977),<br></p>Fórmula:C13H15D5ClNO3Forma y color:NeatPeso molecular:278.793-(5-Nitrofurfurylideneamino)hydantoic Acid
CAS:<p>Impurity Nitrofurantoin USP Related Compound A<br>Applications 3-(5-Nitrofurfurylideneamino)hydantoic Acid, is a new derivative of 5-Nitro-2-furfural, and they are proved to be bactericidal. Nitrofurantoin USP Related Compound A.<br>References Swirska, A., et al.: Rocz. Chem., 31, 1335 (1957);<br></p>Fórmula:C8H8N4O6Forma y color:YellowPeso molecular:256.17(1RS)-1-(6-Methoxy-2-naphthyl)ethanol (Naproxen Impurity K)
CAS:Producto controlado<p>Impurity Naproxen EP Impurity K<br>Applications Naproxen impurity K.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Li, J., et al.: J. Med. Chem., 39, 1846 (1996), Monser, L., et al.: J. Pharm. Biomed. Anal., 27, 851 (2002),<br></p>Fórmula:C13H14O2Forma y color:White To Light YellowPeso molecular:202.25Empagliflozin
CAS:<p>Stability Hygroscopic<br>Applications Empagliflozin is a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Fórmula:C23H27ClO7Forma y color:White To Off-WhitePeso molecular:450.91Ethyl 4-Acetamidobenzoate
CAS:Producto controlado<p>Applications Ethyl 4-acetamidobenzoate is a reagent that is used in the synthesis of DAMPA-d3, which is a labeleld antitumor agent.<br>References Martinelli, J.E., et al.: J. Med. Chem., 22, 869 (1979);<br></p>Fórmula:C11H13NO3Forma y color:Off-WhitePeso molecular:207.235-Nitro-2-furfuraldazine
CAS:Producto controlado<p>Impurity Nitrofurazone USP Related Compound A<br>Applications 5-Nitro-2-furfuraldazine is an impurity in the synthesis of Nitrofurazone (N493880), anti-infective (topical). Antimicrobial. Nitrofurazone USP Related Compound A<br>References Morris, et al.: Cancer Res., 29, 2145 (1969), Sanderson, H., et al.: Toxicol. Lett., 144, 383 (2003),<br></p>Fórmula:C10H6N4O6Forma y color:NeatPeso molecular:278.178(3’S)-ent-Ezetimibe
CAS:<p>Applications An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and cholesterol absorption inhibitor.<br></p>Fórmula:C24H21F2NO3Forma y color:WhitePeso molecular:409.43Diaveridine
CAS:Producto controlado<p>Applications Diaveridine is a dihydrofolate reductase inhibitor. It is used in veterinary medicine as a drug for its anticoccidial properties and its function as an antibacterial synergist.<br>References Wang, H., et al.: J. Chromatogr. B., 965, 91 (2014); Wang, X., et al.: Regul. Toxicol. Pharm., 73, 232 (2015); Sporri, S., et al.: Food. Addit. Contam. A., 31, 806 (2014)<br></p>Fórmula:C13H16N4O2Forma y color:NeatPeso molecular:260.29(R)-(+)-5’-Hydroxyphenyl Carvedilol
CAS:<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Fórmula:C24H26N2O5Forma y color:NeatPeso molecular:422.47N,N'-Dicyclohexylurea
CAS:Producto controlado<p>Impurity Lomustine USP Related Compound C<br>Applications N,N'-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.<br>References Garriga, M., et al.: Chemosphere, 82, 1604 (2011)<br></p>Fórmula:C13H24N2OForma y color:Light YellowPeso molecular:224.34Bupivacaine Hydrochloride
CAS:Producto controlado<p>Applications Bupivacaine HCl (cas# 18010-40-7) is a useful research chemical.<br></p>Fórmula:C18H28N2O·ClHForma y color:NeatPeso molecular:324.89AR-C133913XX
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications AR-C133913XX is an metabolte of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)<br></p>Fórmula:C14H22N6O4SForma y color:NeatPeso molecular:370.43Nortilidine-d3 Hydrochloride
CAS:Producto controladoFórmula:C162H3H18NO2·ClHForma y color:NeatPeso molecular:298.82Nisoldipine
CAS:Producto controlado<p>Applications Dihydropyridine calcium channel blocker. Antihypertensive and antianginal.<br>References Kazda, S., et al.: Arzneimittel-Forsch., 30, 2144 (1980), Pasanisi, F., et al.: Eur. J. Clin. Pharmacol., 29, 21 (1985), Lam, J., et al.: J. Am. Col. Cardiol., 6, 447 (1985)<br></p>Fórmula:C20H24N2O6Forma y color:YellowPeso molecular:388.41(±)-Pramipexole
CAS:<p>Applications (±)-Pramipexole is a recemic analogue of (S)-Pramipexole (P700755), a dopamine-D2-receptor agonist. Antiparkinsonian.<br>References Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)<br></p>Fórmula:C10H17N3SForma y color:NeatPeso molecular:211.3310-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide
CAS:Producto controlado<p>Applications 10-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide is an intermediate in the synthesis of Oxacarbazepine (O869250) related compounds.<br></p>Fórmula:C17H14N2O3Forma y color:NeatPeso molecular:294.30Nilotinib N-Oxide
CAS:Producto controlado<p>Applications A metabolite of Nilotinib (N465300). It is a COVID19-related research product.<br></p>Fórmula:C28H22F3N7O2Forma y color:NeatPeso molecular:545.52(Z)-Thiothixene-d8
CAS:Producto controladoFórmula:C23H21D8N3O2S2Forma y color:NeatPeso molecular:451.67Aripiprazole N1-Oxide
CAS:Producto controlado<p>Impurity Aripiprazole EP Impurity F<br>Stability Hygroscopic<br>Applications Aripiprazole N1-Oxide (Aripiprazole EP Impurity F) is a metabolite of anti-psychotic drug, Aripiprazole (A771000).<br>References Rowley, M., et al.: J. Med. Chem., 44, 477 ( 2001), Ozdemir, V., et al.: Curr. Opin. Invest Drugs 2002, 3, 113,,,4) Jordan, S; European Journal Pharmacol 2002, 441, 137<br></p>Fórmula:C23H27Cl2N3O3Forma y color:NeatPeso molecular:464.38N-Desmethyl-N-cyclopentyl Tadalafil
CAS:Producto controlado<p>Applications N-Desmethyl-N-cyclopentyl Tadalafil is used as a reagent to synthesize tetracyclic cGMP-specific phosphodiesterase inhibitors, compounds that have potential to treat cardiovascular disorders and erectile dysfunction.<br>References Daugan, A. & Gellibert, F. Tetracyclic cGMP-specific Phosphodiesterase Inhibitors and Their Use in Disease Treatment. U.S. 6143746. Nov 7, 2000<br></p>Fórmula:C26H25N3O4Forma y color:NeatPeso molecular:443.492-Phenylphenol
CAS:<p>Applications 2-Phenylphenol is an agricultural fungicide and is no longer used as a food additive (1). It has been associated with the incidence of bladder cancer in male rats which may be related to its primary metabolite, phenylhydroquinone (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gouin T. et al.: Environ Pollut. 2012 Jun;165:208-14. 2. Balakrishnan, S. et al.: Environ Mol Mutagen. 2016 Apr;57(3):210-9<br></p>Fórmula:C12H10OForma y color:Light PinkPeso molecular:170.21rac N-Acetyl-Pseudoephedrine
CAS:Producto controlado<p>Applications rac N-Acetyl Pseudoephedrine is a racemic N-acetylated analogue of the non-selective adrenergic agonist Pseudoephedrine (P839350).<br>References Coutts, R.T. et al.: Biomed. Mass Spec., 11, 441 (1984);<br></p>Fórmula:C12H17NO2Forma y color:NeatPeso molecular:207.274-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde
CAS:<p>Impurity Bisoprolol EP Impurity L (Metoprolol EP Impurity C)<br>Stability Hygrscopic<br>Applications 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehyde (Bisoprolol EP Impurity L (Metoprolol EP Impurity C)) is a Metoprolol impurity .<br>References Baldwin, J.J. , et al.: J. Med. Chem., 29, 1065 (1986), Ravelet, C., et al.: J. Sep. Sci., 29, 1322 (2006),<br></p>Fórmula:C13H19NO3Forma y color:NeatPeso molecular:237.295-[[4-[3-(Aminocarbonyl)-1,4,5,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6H-pyrazolo[3,4-c]pyridin-6-yl]phenyl]amino]pentanoic Acid
CAS:<p>Applications Apixaban Open chain Acid Is an open ring impurity of Apixaban (A726700). Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C25H27N5O5Forma y color:Light YellowPeso molecular:477.51Benzophenone-2,3,4,5,6-d5
CAS:Producto controlado<p>Applications Benzophenone-2,3,4,5,6-d5 is derived from Benzene-d6 (B185282), which is an isotope labelled benzene, an organic compound that is a natural constituent of crude oil and one of the most basic petrochemicals.<br>References Feng, Z.X.. et al.: J. Phys. Chem. Lett. 4, 285 (2013); Pilling. M., et al.: Chem. Eng. Prog., 108, 32 (2012);<br></p>Fórmula:C13D5H5OForma y color:NeatPeso molecular:187.25Riluzole 4-Trifluoromethoxy Isomer
CAS:Producto controlado<p>Applications Riluzole 4-Trifluoromethoxy Isomer is an impurity of Riluzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.<br>References Satyanarayana, B., et. al.: ARKIVOC, 14, 109 (2008); Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Fórmula:C8H5F3N2OSForma y color:NeatPeso molecular:234.20Clozapine N-Oxide-d8
CAS:Producto controladoFórmula:C18H11D8ClN4OForma y color:Yellow To Dark YellowPeso molecular:350.876-chloro-2-(3-methylphenyl)quinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:297.739990234375Suprofen
CAS:<p>Applications Prostaglandin biosynthesis inhibitor. Analgesic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Niemegeers, C.J.E., et al.: Arzneim.-Forsch., 25, 1537 (1975),<br></p>Fórmula:C14H12O3SForma y color:BeigePeso molecular:260.31S-(-)-Etomidate
CAS:Producto controlado<p>Applications Etomidate (E933300) is a hypnotic. This is a stereoisomer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Fórmula:C14H16N2O2Forma y color:NeatPeso molecular:244.294-tert-Butylaminoethyl-2-methylphenol
CAS:Producto controlado<p>Impurity Salbutamol EP Impurity H<br>Applications 4-tert-Butylaminoethyl-2-methylphenol (Salbutamol EP Impurity H) is an impurity of Albuterol Sulfate (Salbutamol Sulfate) (A514500). Albuterol impurity H.<br>References Epshtein, N., et al.: Pharm. Chem. J., 38, 212 (2004), Erram, S., et al.: J. Pharm. Biomed. Anal., 40, 864 (2006),<br></p>Fórmula:C13H21NOForma y color:NeatPeso molecular:207.31N-(4-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
CAS:Fórmula:C14H22N4OForma y color:Off-White To BeigePeso molecular:262.35Demethyl Benzydamine Hydrochloride
CAS:Producto controlado<p>Applications A metabolite of Benzydamine (B209950).<br>References Kataoka, S., et al.: Chem. Pharma. Bull., 21, 358 (1973),<br></p>Fórmula:C18H22ClN3OForma y color:Off White SolidPeso molecular:331.842,3,5-Trimethylpyridine N-Oxide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Intermediate in the preparation of Omeprazole metabolites<br></p>Fórmula:C8H11NOForma y color:Off-White To Light BrownPeso molecular:137.18Omeprazole Sulfide Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Omeprazole Sulfide Hydrochloride is a metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Fórmula:C17H19N3O2S·HClForma y color:NeatPeso molecular:329.42 + 36.46Didesmethyl Cariprazine
CAS:Producto controlado<p>Applications Didesmethyl Cariprazine, s a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.<br>References Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); Seneca, N. et al.: Psychopharmacology, 218, 579 (2011); Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)<br></p>Fórmula:C19H28Cl2N4OForma y color:NeatPeso molecular:399.36Prulifloxacin
CAS:<p>Applications Prulifloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class. Prulifloxacin is a prodrug for active metabolite, Ulifloxacin. Antibacterial.<br>References Ozaki, M., et al.: Antimicrob. Agents Chemother., 35, 2496 (1991), Segawa, J., et al.: J. Med. Chem., 35, 4727 (1992), Nakashima, M., et al.: J. Clin. Pharmacol., 34, 930 (1994),<br></p>Fórmula:C21H20FN3O6SForma y color:NeatPeso molecular:461.46N-Nitroso Paroxetine
CAS:Fórmula:C19H19FN2O4Forma y color:White To Light YellowPeso molecular:358.364N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine Formamide Hydrochloride
CAS:Producto controlado<p>Impurity Alfuzosin Hydrochloride EP Impurity E<br>Applications Alfuzosin (A532000) impurity. Alfuzosin (A532000) is an α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Used in treatment of benign prostatic hypertrophy. (Alfuzosin Hydrochloride EP Impurity E )<br>References Ramage, A.G., et al.: Eur. J. Pharmacol., 129, 307 (1986), Deering, A.H.,: Brit. J. Clin. Pharmacol., 25, 417 (1988), Priolo, L.D., et al.: Eur. J. Clin. Pharmacol., 35, 25 (1988),<br></p>Fórmula:C15H21N5O3·HClForma y color:White To Off-WhitePeso molecular:319.37 + (36.46)Despiperazine Amino Norfloxacin
CAS:Producto controladoFórmula:C12H11FN2O3Forma y color:NeatPeso molecular:250.22rac-Vigabatrin-13C,d2 (Major)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Labelled Vigabatrin. A novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.<br>References Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000), Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004), Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006),<br></p>Fórmula:C513CH9D2NO2Forma y color:White To Dark YellowPeso molecular:132.16Diclazuril 6-Carboxylic Acid
CAS:Producto controlado<p>Applications Diclazuril 6-Carboxylic Acid is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br>References Fodey, T.L., et al.: J. Immunol. Meth., 323, 31 (2007);<br></p>Fórmula:C18H9Cl3N4O4Forma y color:NeatPeso molecular:451.65Paliperidone Palmitate N-Oxide
CAS:Producto controlado<p>Applications Paliperidone Palmitate N-Oxide is a metabolite of Paliperidone Palmitate (P141020).<br></p>Fórmula:C39H57FN4O5Forma y color:NeatPeso molecular:680.89Bromperidol
CAS:<p>Applications Bromine analog of Haloperidol. Antipsychotic.<br>References Niemegeers, C.J.E., et al.: Life Sci., 24, 2201 (1979), Van Den Eeckhout, E., et al.: Eur. J. Drug Metab. Pharmacokinet., 5, 45 (1980), Vincent, S.H., et al.: J. Med. Chem., 23, 75 (1980),<br></p>Fórmula:C21H23BrFNO2Forma y color:NeatPeso molecular:420.32(1R,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
CAS:Producto controlado<p>Applications An intermediate and impurity in the synthesis of Tadalafil (T004500).<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003),<br></p>Fórmula:C20H18N2O4Forma y color:NeatPeso molecular:350.37Mirtazapine N-Glucuronide (Mixture of Diastereomers) Contains Unknown Inorganics >80%
CAS:Producto controlado<p>Applications Mirtazapine N-Glucuronide is a metabolite of Mirtazapine (M365000), an α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.<br>References Smith, D.A., RSC Drug Discovery Series, 1, 193 (2010); De Boer, T., et al.: Neuropharmacology, 27, 399 (1988); Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Fórmula:C23H28N3O6Pureza:>80%Forma y color:NeatPeso molecular:442.48Minoxidil-d10
CAS:Producto controlado<p>Applications Deuterated Minoxidil, which is used as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Franz, T.J., Arch. Dermatol., 121, 203 (1985), Gadwood, R.C., et al.: Annu. Rep. Med. Chem., 24, 187 (1989), Hautala, T., et al.: Biochem. J., 283, 51 (1992)<br></p>Fórmula:C92H10H5N5OForma y color:White To Off-WhitePeso molecular:219.312-Amino-5-ethyl-thiophene-3-carboxylic acid methylester
CAS:Fórmula:C8H11NO2SPureza:95+%Forma y color:SolidPeso molecular:185.24Trametinib-13C6
CAS:Producto controlado<p>Applications Trametinib-13C6 is the labelled compound form of Trametinib (C988930), which is used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor and potent MEK inhibitor.<br>References Ercan, D., et al.: Canc. Disc., 2, 934 (2012); Mackiewicz-Wysocka, M., et al.: Exp. Opin. Investig. Drugs., 22, 181 (2013);<br></p>Fórmula:C6C20H23FIN5O4Forma y color:NeatPeso molecular:621.351Apixaban PG Ester-I
CAS:Producto controlado<p>Applications Apixaban PG Ester-I is one of the multiple constituents extracted from Biebersteinia multifida, that exhibits inhibitory activity on acetylcholinesterase.<br>References Xiang, F., et al.: Faming Zhuanli Shenqing (2019), CN 109432093 A 20190308.<br></p>Fórmula:C28H30N4O6Forma y color:NeatPeso molecular:518.56(S)-Naproxen Sodium Salt
CAS:<p>Applications An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Fórmula:C14H13O3·NaForma y color:Off White SolidPeso molecular:252.24(R)-Naproxen Acyl-β-D-glucuronide
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Naproxen.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Jin, C., et al.: J. Pharmacol. Exp. Ther., 264, 475 (1993),King, C., et al.: Toxicol. Sci., 61, 49 (2001), Aresta, A., et al.: J. Pharm. Biomed. Anal., 39, 643 (2005),<br></p>Fórmula:C20H22O9Forma y color:NeatPeso molecular:406.38Ranitidine Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications A histamine H2-receptor antagonist which inhibits gastric acid secretion. Antiulcerative.<br>References Bradshaw, J., et al.: Brit. J. Pharmacol., 66, 464 (1979), Berstad, A., et al.: Scand. J. Gastroenterol, 15, 637 (1980), Hohnjec, M., et al.: Anal. Profiles Drug Subs., 15, 533 (1986),<br></p>Fórmula:C13H22N4O3S·ClHForma y color:NeatPeso molecular:350.86Vildagliptin Cyclo Imidamide
CAS:<p>Applications Vildagliptin Cyclo Imidamide Hydrochloride is an impurity of vildagliptin (V305000). Glyptins are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. ASide from there use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Fórmula:C17H25N3O2Forma y color:NeatPeso molecular:303.406-Amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one
CAS:Producto controlado<p>Applications 6-Amino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-7,9-dihydro-8H-purin-8-one is derived from 2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5-6-triamine (F595655), which is a metabolite of stimulators of soluble guanylate cyclase for the treatment of pulmonary hypertension;Also, it is an impurity of Riociguat (R520000), which is used in the treatment for pulmonary hypertension.<br>References Mittendorf, J., et al.: ChemMedChem, 4, 853 (2009); Straub, A., et al.: Bioorg. Med. Chem., 10, 1711 (2002); Straub, A., et al.: Bioorg. Med. Chem., 10, 3075 (2002);Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C18H13FN8OForma y color:NeatPeso molecular:376.3472-Ethyl-2-phenylmalonamide-d5
CAS:Producto controlado<p>Applications A labelled metabolite of Primidone.<br>References Holler, M., et al.: Biochem. Pharmacol., 33, 1753 (1984), Lafont, O., et al.: Eur. J. Med. Chem., 25, 61 (1990), Fisher, J., et al.: Pharmacol. Res., 26, 207 (1992), Florence, A., et al.: Pharmacol. Res., 14, 259 (1997), El-Masri, H., et al.: Drug Metab. Dispos., 26, 585 (1998),<br></p>Fórmula:C11H9D5N2O2Forma y color:NeatPeso molecular:211.27Dofetilide N-Oxide
CAS:Producto controladoFórmula:C19H27N3O6S2Forma y color:NeatPeso molecular:457.56Dehydro Felodipine-d3
CAS:Producto controladoFórmula:C18H14D3Cl2NO4Forma y color:NeatPeso molecular:385.26Mephenoxalone
CAS:Producto controlado<p>Applications Muscle relaxant, also used as a mild tranquilizer.<br>References Erk N., et al.: J. Pharm. Biomed. Anal., 21, 429(1999), Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006),<br></p>Fórmula:C11H13NO4Forma y color:NeatPeso molecular:223.23Levofloxacin-d3
CAS:Producto controlado<p>Applications Levofloxacin-d3, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Fórmula:C18H17D3FN3O4Forma y color:NeatPeso molecular:364.393-Cyclopropylmethoxy-4-difluoromethoxybenzoic Acid
CAS:Producto controlado<p>Applications An impurity and intermediate in the preparation of selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).<br></p>Fórmula:C12H12F2O4Forma y color:NeatPeso molecular:258.223-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanoic Acid
CAS:Producto controladoFórmula:C16H21N5O3Forma y color:NeatPeso molecular:331.374-(2-Nitroanilino)pyridine
CAS:Producto controlado<p>Impurity Droperidol Impurity 4<br>Applications 4-(2-Nitroanilino)pyridine can be used to increase the yield of 4-(2-Aminoanilino)pyridine (A583160) dihydrochloride by hydrogenation in the presence of a Ni-Cr catalyst. Droperidol Impurity 4.<br>References Avots, A., et al.: U.S.S.R., SU 1318592 A1 19870623<br></p>Fórmula:C11H9N3O2Forma y color:NeatPeso molecular:215.208Gimeracil-13C3
CAS:Producto controlado<p>Applications Antitumor agent. A potent inhibitor of dihydropyrimidine dehydrogenase (DPD).<br>References Shirasaka, T., et al.: Cancer Res., 56, 2602 (1996), Patt, Y., et al.: J. Clin. Oncol., 22, 271 (2004), Shirao, K., et al.: Cancer, 100, 2355 (2004), Kelly, H., et al.: J. Clin. Oncol., 23, 4553 (2005),<br></p>Fórmula:C213C3H4ClNO2Forma y color:NeatPeso molecular:148.52[3-cyclopropyl-4-(difluoromethyl)-6-(1-ethyl-5-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl]acetic acid
CAS:Pureza:95.0%Peso molecular:375.3800048828125Aprepitant N-Oxide
CAS:Producto controladoFórmula:C23H21F7N4O4Forma y color:NeatPeso molecular:550.426Benzidine
CAS:Producto controlado<p>Applications Potentially mutagenic compound. Dyes and metabolites, Environmental Testing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dairou, J., et al.: Toxicol. App. Pharmacol., 236, 366 (2009), Toropov, A., et al.: Chem. Biol. Drug Design, 73, 482 (2009),<br></p>Fórmula:C12H12N2Pureza:95%Forma y color:Tan Or Dark Grey To BlackPeso molecular:184.24Prochlorperazine Dimaleate
CAS:Producto controladoFórmula:C20H24ClN3S·2C4H4O4Forma y color:Off-WhitePeso molecular:606.09Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H22N4O3Forma y color:NeatPeso molecular:330.38Propyzamide
CAS:Producto controlado<p>Applications Selective pre-emergence herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viste, K.L., et al.: Science, 167, 280 (1970), Yoshii, K., et al.: J. Agric. Food Chem., 48, 2502 (2000), Paya, P., et al.: Anal. Bioanal. Chem., 389, 1697 (2007),<br></p>Fórmula:C12H11Cl2NOForma y color:WhitePeso molecular:256.135-Hydroxypyrazine-2-carboxylic Acid
CAS:<p>Applications A versatile building block for the synthesis of new antituberculous agents. A metabolite of Pyrazinamide (P840600).<br>References Wieser, M. et al.: Appl. Microbiol. Biotech., 48, 174 (1997); Lacroix, C. et al.: Eur. J. Clin. Pharmacol., 36, 395 (1989);<br></p>Fórmula:C5H4N2O3Forma y color:Light YellowPeso molecular:140.10Desbutyl Dronedarone Hydrochloride
CAS:<p>Impurity Dronedarone USP Related Compound A<br>Applications A metabolite of Dronedarone (D679445). Dronedarone impurity D. Dronedarone USP Related Compound A.<br>References Bolderman, R.W. et al.: J Chrom. B:Anal. Tech. Biomed. Life Sci., 887, 1727 (2009); Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008); Hoy, S., et al.: Drugs, 69, 1647 (2009);<br></p>Fórmula:C27H36N2O5S·ClHForma y color:NeatPeso molecular:537.112,6-Dichloro-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
CAS:Producto controlado<p>Applications An antitumor nucleoside pyrimido pyrimidine.<br>References Shih, C., et al.: Cancer Res., 57, 1116 (1997), Smith, P., et al.: Clin. Cancer Res., 7, 2105 (2001), Cunningham, D., et al.: Eur. J. Cancer, 38, 478 (2002), Hughes, A., et al.: J. Clin. Oncol., 20, 3533 (2002),<br></p>Fórmula:C16H20Cl2N6Forma y color:NeatPeso molecular:367.28ent-Paroxetine Hydrochloride
CAS:Producto controlado<p>Impurity Paroxetine EP Impurity D; Paroxetine USP Related Compound C<br>Applications ent-Paroxetine Hydrochloride (Paroxetine EP Impurity D; Paroxetine USP Related Compound C) is an enantiomeric impurity of Paroxetine (P205750).<br>References Engelstoft, M. et al.: Acta Chem. Scand. , 50, 164 (1996);<br></p>Fórmula:C19H20FNO3·ClHForma y color:Off-WhitePeso molecular:365.835-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole
CAS:Producto controlado<p>Applications Sitagliptin intermediate. An anti-hypertensive agent for the treatment of diabetes and hypertension.<br>References Sarges, R, et al.: J. Med. Chem., 33, 2240 (1990),<br></p>Fórmula:C4H2ClF3N2OForma y color:NeatPeso molecular:186.52Vioxx-d5 (Major)
CAS:Producto controlado<p>Applications A selective labelled cyclooxygenase-2 (COX-2) inhibitor. Use as an anti-inflammatory, analgesic.<br>References Catalla-Lawson, F., et al.: J. Pharmacol. Exp. Ther., 289, 735 (1999), Ehrich, E.W., et al.: Clin. Pharmacol. Ther., 65, 336 (1999), Langman, M.J., et al.: J. Am. Med. Assoc., 282, 1929 (1999),<br></p>Fórmula:C172H5H9O4SForma y color:NeatPeso molecular:319.387(S)-Penbutolol Sulfate
CAS:<p>Stability Hygroscopic<br>Applications (S)-Penbutolol Sulfate is an isomer of Penbutolol (P220500), a β-adrenoceptor antagonist. Antihypertensive.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>Fórmula:C18H29NO2·H2O4SForma y color:NeatPeso molecular:680.94Perampanel
CAS:Producto controlado<p>Applications Perampanel is a novel, noncompetitive AMPA receptor antagonist for the treatment of epilepsy. Also in the treatment of primary generalized tonic-clonic seizures in idiopathic generalized epilepsy. Perampanel is a selective non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor antagonist that reduces neuronal excitation (1,2,3,4).<br>References (1) Shih, J., et al.: Therap. Clinical Risk Management, 9, 285 (2013)(2) Rogawski, M. A., et al.: Epilepsy Curr., 11, 56 (2011)(3) Franco, V., et al.: Ther Drug Monit. 38, 744 (2016) (4) Rudzinski, L. A., et al.: J Investig Med. 64, 1087 (2016)<br></p>Fórmula:C23H15N3OForma y color:Light YellowPeso molecular:349.38
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