Derivados de Quinazolina y Quinolina
Las quinazolinas y quinolinas son compuestos heterocíclicos nitrogenados con estructuras aromáticas que desempeñan un papel clave en la síntesis de fármacos con actividad anticancerígena, antimicrobiana y antiinflamatoria. Sus derivados presentan modificaciones estructurales que optimizan su biodisponibilidad y selectividad, lo que permite el desarrollo de nuevos principios activos para diversas aplicaciones terapéuticas. Estos compuestos se utilizan en la fabricación de APIs destinados al tratamiento de cáncer, infecciones, enfermedades neurodegenerativas y cardiovasculares. Además, los derivados de quinazolina y quinolina son esenciales en la investigación de inhibidores enzimáticos y en el diseño de moléculas bioactivas innovadoras. En CymitQuimica disponemos de derivados de quinazolina y quinolina de alta pureza para aplicaciones en síntesis química, desarrollo farmacéutico y biotecnología.
Se han encontrado 65576 productos de "Derivados de Quinazolina y Quinolina"
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Celiprolol hydrochloride
CAS:<p>Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.</p>Fórmula:C20H33N3O4·HClForma y color:White Crystalline SolidPeso molecular:415.96MMP-3 Inhibitor VIII
CAS:<p>Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.</p>Fórmula:C20H26N2O5SForma y color:SolidPeso molecular:406.5Yonkenafil
CAS:<p>Yonkenafil, a PDE5 inhibitor, may reduce stroke damage and aid in Alzheimer's treatment.</p>Fórmula:C24H33N5O4SForma y color:SolidPeso molecular:487.61Collagen proline hydroxylase inhibitor
CAS:<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Fórmula:C18H18N4O4Pureza:98%Forma y color:SolidPeso molecular:354.36Dibenamine hydrochloride
CAS:<p>Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.</p>Fórmula:C16H19Cl2NPureza:96.43%Forma y color:Oily Liquid SolidPeso molecular:296.23Ro 31-9790
CAS:<p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>Fórmula:C15H29N3O4Pureza:98%Forma y color:SolidPeso molecular:315.41Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Fórmula:C24H27ClN2O2Pureza:99.37% - 99.62%Forma y color:SolidPeso molecular:410.94Tianagliflozin
CAS:<p>Tianagliflozin, a sodium/glucose cotransporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Fórmula:C21H25ClO5Pureza:98%Forma y color:SolidPeso molecular:392.87Bufuralol (hydrochloride)
CAS:<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Fórmula:C16H24ClNO2Forma y color:SolidPeso molecular:297.82Saredutant
CAS:<p>Saredutant (SR 48968) is a selective neurokinin-2 (NK2) receptor antagonist that inhibits neurokinin A by blocking NK2 receptor, antidepressant and anxiolytic.</p>Fórmula:C31H35Cl2N3O2Pureza:99.12%Forma y color:SolidPeso molecular:552.54RU 58668
CAS:<p>Pure antiestrogen that downregulates estrogen receptor expression</p>Fórmula:C34H43F5O5SPureza:98%Forma y color:SolidPeso molecular:658.76Gisadenafil
CAS:<p>Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.</p>Fórmula:C23H33N7O5SPureza:98.82% - 99.50%Forma y color:SolidPeso molecular:519.62Frovatriptan
CAS:<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Fórmula:C14H17N3OForma y color:SolidPeso molecular:243.3Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Fórmula:C22H25Cl2N3O3Pureza:99.36%Forma y color:SolidPeso molecular:450.36Fluvalinate
CAS:<p>Fluvalinate is a synthetic chemical compound and can be commonly used to control varroa mites in honey bee colonies.</p>Fórmula:C26H22ClF3N2O3Forma y color:SolidPeso molecular:502.91PIM447
CAS:<p>PIM447 (LGH447) is a pan-PIM kinase inhibitor with anti-tumor and bone protective effects. PIM447 reduces the viability, and motility of HuH6 cell.</p>Fórmula:C24H23F3N4OPureza:98.97%Forma y color:SolidPeso molecular:440.46Caroverine
CAS:<p>Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.</p>Fórmula:C22H27N3O2Forma y color:SolidPeso molecular:365.47Pirtobrutinib
CAS:<p>Pirtobrutinib: a selective, non-covalent BTK inhibitor effective against BTK C481 mutations, causing tumor regression in lymphoma models.</p>Fórmula:C22H21F4N5O3Pureza:99.76% - 99.94%Forma y color:SolidPeso molecular:479.43(Rac)-Lonafarnib
CAS:<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Fórmula:C27H31Br2ClN4O2Forma y color:SolidPeso molecular:638.82MMP3 inhibitor 1
CAS:<p>MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).</p>Fórmula:C23H31N3O6SPureza:98%Forma y color:SolidPeso molecular:477.57Mefenidil
CAS:<p>Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.</p>Fórmula:C12H11N3Pureza:98.27%Forma y color:SolidPeso molecular:197.24LY52
CAS:<p>LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.</p>Fórmula:C22H24N4O6Pureza:98%Forma y color:SolidPeso molecular:440.45Z-PDLDA-NHOH
CAS:<p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>Fórmula:C22H32N4O6Forma y color:SolidPeso molecular:448.51MMP13-IN-3
CAS:<p>MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.</p>Fórmula:C24H22N4O5Pureza:99.76%Forma y color:SolidPeso molecular:446.46IK-862
CAS:<p>IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.</p>Fórmula:C25H27N3O4Pureza:97.75% - 98.29%Forma y color:SolidPeso molecular:433.5MMP-7-IN-2
CAS:<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Fórmula:C28H40ClF3N6O9SPureza:97.82%Forma y color:SolidPeso molecular:729.17Bufuralol
CAS:<p>Bufuralol (Ro 3-4787) is a 尾-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.</p>Fórmula:C16H23NO2Pureza:98.26%Forma y color:SolidPeso molecular:261.36KB-R7785
CAS:<p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>Fórmula:C18H27N3O4Forma y color:SolidPeso molecular:349.42Dothiepin
CAS:<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Fórmula:C19H21NSPureza:98%Forma y color:SolidPeso molecular:295.44XL-784
CAS:<p>XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.</p>Fórmula:C42H42Cl2F4MgN6O16S2Pureza:98%Forma y color:SolidPeso molecular:1122.15Naxagolide free base
CAS:<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Fórmula:C15H21NO2Pureza:98%Forma y color:SolidPeso molecular:247.33Gepirone
CAS:<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Fórmula:C19H29N5O2Pureza:99.35% - 99.89%Forma y color:SolidPeso molecular:359.47Ro 32-7315
CAS:<p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>Fórmula:C22H35N3O5SPureza:98%Forma y color:SolidPeso molecular:453.6Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Fórmula:C26H29FN2O2Forma y color:SolidPeso molecular:420.52Apratastat
CAS:<p>Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)</p>Fórmula:C17H22N2O6S2Pureza:98%Forma y color:SolidPeso molecular:414.5Cipemastat
CAS:<p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>Fórmula:C22H36N4O5Pureza:98%Forma y color:SolidPeso molecular:436.554-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride
CAS:<p>4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride is a drug product. It is used as an analytical standard and in the development of drugs. The metabolite of 4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride, 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N-(4-nitrophenyl)benzamide, has been shown to inhibit the production of cytokines IL6 and TNFα by human monocytes, macrophages, and dendritic cells. Metabolism studies have shown that 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N</p>Fórmula:C13H20ClNO3Pureza:Min. 95%Peso molecular:273.76 g/mol1-(6-Chloro-9H-carbazol-2-yl)ethanone
CAS:<p>1-(6-Chloro-9H-carbazol-2-yl)ethanone is a chemical substance that belongs to the class of synthetic drugs. It is used as a pharmaceutical intermediate in the production of other chemical substances, including antibiotics and antihypertensives. 1-(6-Chloro-9H-carbazol-2-yl)ethanone has been shown to be metabolized by cytochrome P450 enzymes and by glucuronidases or esterases. This product can also be used as an impurity standard for HPLC analyses of fluoroquinolones.</p>Fórmula:C14H10ClNOPureza:Min. 95%Peso molecular:243.69 g/molAderamastat
CAS:<p>Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.</p>Fórmula:C21H18N2O4SPureza:99.35%Forma y color:SolidPeso molecular:394.44Sitagliptin impurity E
CAS:<p>Sitagliptin impurity E is an inhibitor of dipeptidyl peptidase-4 (DPP-IV) that is used as a hypoglycemic agent. Sitagliptin impurity E has been shown to increase the glucose-lowering effect in diabetic patients with type 2 diabetes mellitus. It is also effective in reducing postprandial glucose and insulin levels. Sitagliptin impurity E has been shown to increase the concentration of insulin in plasma for up to 24 hours after administration, which suggests that it may be useful for the treatment of metabolic disorders such as obesity and type 2 diabetes mellitus.</p>Fórmula:C16H15F6N5OPureza:Min. 95%Peso molecular:407.31 g/mol7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole
CAS:<p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>Fórmula:C18H18N4Pureza:Min. 95%Peso molecular:290.36 g/molMaralixibat Chloride
CAS:<p>Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.</p>Fórmula:C40H56ClN3O4SPureza:99.19% - 99.65%Forma y color:SolidPeso molecular:710.41Collagen proline hydroxylase inhibitor-1
CAS:<p>Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。</p>Fórmula:C24H21N5O4Pureza:99.62%Forma y color:SolidPeso molecular:443.45Elobixibat
CAS:<p>Elobixibat (A 3309) blocks IBAT in mice/humans/dogs (IC50: 0.13/0.53/5.8 nM); used for constipation research.</p>Fórmula:C36H45N3O7S2Pureza:97.43% - 98.03%Forma y color:SolidPeso molecular:695.89Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Fórmula:C24H28FN3OPureza:99.68% - 99.91%Forma y color:SolidPeso molecular:393.52-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid
CAS:<p>This is a synthetic, impurity standard for 2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid (CAS No. 1159977-03-3) that can be used in the drug product development process. This product is available as a custom synthesis and as an analytical standard for HPLC. It is also available as a pharmacopoeia grade material. The compound has been shown to have niche applications in metabolism studies and natural products research.</p>Fórmula:C10H9Cl2N3O2Pureza:Min. 95%Peso molecular:274.1 g/mol11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine
CAS:<p>11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine is a molecule that inhibits the replication of DNA and RNA in viruses. The structure of 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine has been determined by X-ray crystallography. Hepatocyte cells were used for this study because they are important for the metabolism of drugs. This molecule binds to serine proteases and prevents them from functioning properly. It also inhibits the replication of hepatitis C virus and human immunodeficiency virus type 1 (HIV-1). 11,11'-(1,4-Piperazinediyl)bis-dibenzo[b,f][1,4]thiazepine can be used as a template for designing other molecules with antiviral</p>Fórmula:C30H24N4S2Pureza:Min. 95%Forma y color:Yellow SolidPeso molecular:504.67 g/molRodatristat
CAS:<p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>Fórmula:C27H27ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:561.98UK-370106
CAS:<p>UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-</p>Fórmula:C35H44N2O5Pureza:98%Forma y color:SolidPeso molecular:572.73Lisuride
CAS:<p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>Fórmula:C20H26N4OForma y color:SolidPeso molecular:338.45HU-308
CAS:<p>HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.</p>Fórmula:C27H42O3Forma y color:SolidPeso molecular:414.62BAY-7598
CAS:<p>BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).</p>Fórmula:C28H31N3O6Pureza:98%Forma y color:SolidPeso molecular:505.563-Aminobenzene-1,2-diol
CAS:<p>3-Aminobenzene-1,2-diol (compound C8) is an inhibitor of matrix metalloproteinases (MMP), with IC50 values of 20, 26, 16, and 16.3 μM against MMP-2, MMP-8, MMP-9, and MMP-14, respectively.</p>Fórmula:C6H7NO2Forma y color:SolidPeso molecular:125.13Faldaprevir
CAS:<p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>Fórmula:C40H49BrN6O9SPureza:99.04% - 99.19%Forma y color:SolidPeso molecular:869.82COTI-219
CAS:<p>COTI-219 is an oral inhibitor of KRAS with antitumor properties [1].</p>Fórmula:C17H18N6SForma y color:SolidPeso molecular:338.43Arterolane
CAS:<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Fórmula:C22H36N2O4Forma y color:SolidPeso molecular:392.53PNU-248686A
CAS:<p>PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).</p>Fórmula:C22H18ClNaO5S2Pureza:98%Forma y color:SolidPeso molecular:484.95ZK159222
CAS:<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Fórmula:C32H48O5Pureza:98%Forma y color:SolidPeso molecular:512.72Tofogliflozin
CAS:<p>Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).</p>Fórmula:C22H26O6Pureza:98%Forma y color:SolidPeso molecular:386.44(3S,4R)-Tofacitinib
CAS:<p>(3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).</p>Fórmula:C16H20N6OPureza:98%Forma y color:SolidPeso molecular:312.37RJF02215
CAS:<p>RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.</p>Fórmula:C17H12ClN3OS3Forma y color:SolidPeso molecular:405.95RuDiOBn
CAS:<p>RuDiOBn exhibits low antioxidant activity by scavenging DPPH and ABTS free radicals with scavenging rates of 13.2% and 5.9% at a concentration of 100 μg/mL. It inhibits collagen glycation and reduces the formation of advanced glycation end-products (AGE) with an IC50 of 2.45 μg/mL. RuDiOBn also enhances fibroblast proliferation and migration, stimulates collagen synthesis, and aids in skin repair and regeneration while inhibiting collagenase.</p>Fórmula:C29H22O7Forma y color:SolidPeso molecular:482.481UK 356618
CAS:<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Fórmula:C34H43N3O4Pureza:98%Forma y color:SolidPeso molecular:557.72Vibegron
CAS:<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Fórmula:C26H28N4O3Forma y color:SolidPeso molecular:444.53CM-352
CAS:<p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>Fórmula:C24H29N3O6SPureza:99.36%Forma y color:SolidPeso molecular:487.57Quinagolide Free Base
CAS:<p>Quinagolide Free Base is a non-ergot dopamine D(2)-agonist.</p>Fórmula:C20H33N3O3SForma y color:SolidPeso molecular:395.56Thioquinapiperifil dihydrochloride
CAS:<p>Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.</p>Fórmula:C24H29ClN6OSPureza:98.73%Forma y color:SolidPeso molecular:485.05Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Fórmula:C20H21Br2N5O4SPureza:98%Forma y color:SolidPeso molecular:587.29Finafloxacin
CAS:<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Fórmula:C20H19FN4O4Forma y color:SolidPeso molecular:398.39Quinapril
CAS:<p>Quinapril is an orally active, non-peptide, and non-thiol angiotensin-converting enzyme (ACE) inhibitor. It primarily blocks the conversion of angiotensin I to angiotensin II in both plasma and tissues. Upon enzymatic hydrolysis, Quinapril is converted into the pharmacologically active Quinaprilat and is effective in hypertension models.</p>Fórmula:C25H30N2O5Forma y color:SolidPeso molecular:438.516SD-2590 HCl
CAS:<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Fórmula:C22H26ClF3N2O7SPureza:98%Forma y color:SolidPeso molecular:554.96Tezosentan
CAS:<p>Tezosentan is an antagonist of the endothelin receptor (pA2s: 9.5, 7.7 for ETA and ETB receptors, respectively).</p>Fórmula:C27H27N9O6SPureza:98%Forma y color:SolidPeso molecular:605.63Tipelukast
CAS:<p>Tipelukast (KCA 757), an oral drug for asthma research, blocks leukotrienes and fights inflammation and fibrosis.</p>Fórmula:C29H38O7SPureza:>99.99%Forma y color:SolidPeso molecular:530.67SD-7300
CAS:<p>SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.</p>Fórmula:C21H30F3N3O7SForma y color:SolidPeso molecular:525.54OncoFAP
CAS:<p>OncoFAP is an ultra-high affinity fibroblast activating protein (FAP) ligand with potential tumour targeting.</p>Fórmula:C21H19F2N5O5Pureza:99.77%Forma y color:SolidPeso molecular:459.40Beloranib
CAS:<p>Beloranib is a fumagillin anticancer drug. Beloranib belongs to an angiogenesis inhibitor.</p>Fórmula:C29H41NO6Pureza:98%Forma y color:SolidPeso molecular:499.64Aclidinium
CAS:<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Fórmula:C26H30NO4S2Forma y color:SolidPeso molecular:484.65Indinavir monohydrate
CAS:<p>Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.</p>Fórmula:C36H49N5O5Forma y color:SolidPeso molecular:631.82Neptinib
CAS:<p>Neptinib (NEP010), a derivative of Afatinib, exhibits enhanced antitumor properties and improved pharmacokinetics when administered orally. It demonstrates a notable suppression of tumor expansion in mouse models of non-small cell lung cancer harboring various EGFR mutations. Furthermore, Neptinib effectively inhibits the EGFR kinase family, exhibiting IC 50 values of 0.24 nM for EGFR wt, 7.25 nM for EGFR L858R/T790M, 0.46 nM for EGFR L858R, and 1.79 nM for EGFR T790M.</p>Fórmula:C22H23ClFN5O2Forma y color:SolidPeso molecular:443.90Vecabrutinib
CAS:<p>Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.</p>Fórmula:C22H24ClF4N7O2Pureza:99.74%Forma y color:SolidPeso molecular:529.92Aleglitazar
CAS:<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Fórmula:C24H23NO5SPureza:99.03%Forma y color:SolidPeso molecular:437.51Obicetrapib
CAS:<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Fórmula:C32H31F9N4O5Pureza:99.26% - >99.99%Forma y color:SolidPeso molecular:722.6(S)-Rasagiline
CAS:<p>(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.</p>Fórmula:C12H13NForma y color:SolidPeso molecular:171.24(4-Methylbenzoyl)trifluoroacetone (1,1,1-Trifluoro-4-hydroxy-4-(4-methylphenyl)-3-buten-2-one)
CAS:Ketones and quinones, w/not with other oxygen function,and their halogenated,sulfated,nitrated,or nitrosated derivatives, nesoiFórmula:C11H9F3O2Forma y color:White SolidPeso molecular:230.05546Ezetimibe Desfluoroaniline Analog ((3R,4S)-3-[(S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one)
CAS:Lactams, nesoiFórmula:C24H22FNO3Forma y color:White Off-White PowderPeso molecular:391.15837Everolimus System Suitability Mixture (This is a mixture of Everolimus, Everolimus oxepane isomer and 9-O-Hydroxyethyl Sirolimus)
Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiForma y color:White Yellow PowderRivaroxaban Open Ring ((R)-5-chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C18H20ClN3O4SForma y color:Off-White SolidPeso molecular:409.0863Methoxyamiodarone ([2-[(1RS)-1-Methoxybutyl]benzofuran-3-yl][4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone) (DISCONTINUED)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFórmula:C26H31I2NO4Forma y color:Colorless GelPeso molecular:675.03425Dasatinib
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFórmula:C22H26ClN7O2S·H2OPeso molecular:505.16629Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFórmula:C16H17N3O2SForma y color:White Off-White SolidPeso molecular:315.10415Acetyl Rotigotine Hydrochloride ((S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-yl acetate hydrochloride)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C21H28ClNO2SForma y color:Off-White SolidPeso molecular:393.15293Ezetimibe Ketone ((3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFórmula:C24H19F2NO3Forma y color:White SolidPeso molecular:407.1333Ezetimibe Tetrahydropyran Analog ((2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFórmula:C24H21F2NO3Forma y color:White Off-White SolidPeso molecular:409.14895Apremilast R-Enantiomer
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Fórmula:C22H24N2O7SForma y color:White Off-White PowderPeso molecular:460.13042Levetiracetam acid ((S)-2-(2-oxopyrrolidin-1-yl)butanoic acid)
CAS:<p>Lactams, nesoi</p>Fórmula:C8H13NO3Forma y color:Off-White SolidPeso molecular:171.08954Ezetimibe 2-Fluorobenzene Isomer ((3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(2-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFórmula:C24H21F2NO3Forma y color:White Off-White SolidPeso molecular:409.14895Apremilast Related Compound E
CAS:Other aromatic organo-sulfur compounds (excluding pesticides)Fórmula:C22H24N2O7SForma y color:Pale Yellow PowderPeso molecular:460.13042Dasatinib Related Compound A
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFórmula:C22H26ClN7O3SPeso molecular:503.15064Methylbis(2-pyridylethyl)amine Hydrochloride (N-Methyl-N,N-bis(2-pyridin-2-yl-ethyl)amine trihydrochloride)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFórmula:C15H19N3·3HClForma y color:Light Brown PowderPeso molecular:241.1579
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