Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4949 productos de "Esteroides y derivados"
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Atorvastatin epoxy tetrahydrofuran impurity
CAS:<p>Atorvastatin epoxy tetrahydrofuran impurity is a byproduct of the synthesis process. It is a white crystalline powder that is soluble in organic solvents and sparingly soluble in water. Atorvastatin epoxy tetrahydrofuran impurity has been shown to be an impurity of atorvastatin. It is not known to have any biological activity, but it may pose a health risk if present in large quantities.</p>Fórmula:C26H24FNO5Pureza:Min. 95%Forma y color:PowderPeso molecular:449.47 g/mol(5α)-17-(3-Pyridinyl)androst-16-en-3-one
CAS:Producto controlado<p>(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.</p>Fórmula:C24H31NOPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:349.51 g/molAtorvastatin epoxy pyrrolooxazin tricyclic impurity
<p>Atorvastatin is a drug product that is metabolized to atorvastatin epoxy pyrrolooxazin tricyclic impurity. Due to the presence of this impurity, the purity of the drug product is not 100%. Atorvastatin epoxy pyrrolooxazin tricyclic impurity is a natural metabolite with CAS number 516-80-1. It has been shown to have effects on metabolism and may be involved in the development of atherosclerosis. Metabolism studies have been conducted on animals, but not humans.</p>Fórmula:C33H32FN2NaO6Pureza:Min. 95%Peso molecular:594.61 g/molAtorvastatin lactone
CAS:<p>Atorvastatin lactone is a prodrug for atorvastatin. It is an inhibitor of the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis and reduces LDL cholesterol levels. Atorvastatin lactone is absorbed from the gut into the bloodstream and then converted to atorvastatin, which has a higher potency than atorvastatin lactone. This conversion occurs in the liver by cytochrome P450 enzymes, including cytochrome CYP3A4. The pharmacokinetics of atorvastatin lactone are influenced by drugs that inhibit these enzymes. Atorvastatin and its metabolites are excreted in human serum as glucuronide or sulfate conjugates.</p>Fórmula:C33H33FN2O4Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:540.62 g/molCalcipotriol EP Impurity H
<p>Calcipotriol EP Impurity H is an impurity found in calcipotriol EP. It is a metabolite of calcipotriol EP, which is the active ingredient in Dovonex. Calcipotriol EP Impurity H can be detected by HPLC with a retention time of 11.5 minutes and its purity can be determined by UV spectroscopy at 254 nm with a purity of >98%. Calcipotriol EP Impurity H can also be synthesized from natural or synthetic sources.</p>Fórmula:C54H78O5Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:807.19 g/molAtorvastatin EP Impurity D
CAS:<p>Soluble in Chloroform & in Methanol Confirmed<br>Insoluble in Water</p>Pureza:95.0% MinForma y color:White or Off-White Crystalline Solid, Light SensitivePeso molecular:431,46β-Epoxyabiraterone acetate
CAS:<p>Beta-Epoxyabiraterone acetate is a synthetic and natural metabolite of abiraterone that is used as an API impurity in the synthesis of abiraterone acetate. The drug product is a niche compound with CAS No. 52464-96-6. The Metabolite is an impurity found in the synthesis of beta-epoxyabiraterone acetate. Drug development research and development, analytical methods, and pharmacopoeia are all involved in the production of this compound.</p>Fórmula:C26H33NO3Pureza:Min. 90 Area-%Forma y color:White Off-White PowderPeso molecular:407.55 g/mol(3R,5S)-Atorvastatin sodium salt
CAS:<p>(3R,5S)-Atorvastatin sodium salt is a synthetic compound that is used in the treatment of high cholesterol. It belongs to the class of statins, which are used for lowering blood cholesterol levels. The drug product contains at least 99% by weight of (3R,5S)-atorvastatin sodium salt. This product also has an analytical purity greater than 98%. It is metabolized via oxidation and hydroxylation to form metabolites that exhibit pharmacological activity similar to the parent molecule. (3R,5S)-Atorvastatin sodium salt is a natural product that can be found in plants such as yew trees. This drug has been shown to have niche applications in drug development and research and development.</p>Fórmula:C33H34FN2NaO5Pureza:Min. 95%Forma y color:PowderPeso molecular:580.62 g/molTravoprost
CAS:<p>Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.</p>Fórmula:C26H35F3O6Pureza:97.39% - 99.58%Forma y color:Colorless OilPeso molecular:500.55Atorvastatin
CAS:<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Fórmula:C33H35FN2O5Pureza:99.37% - 99.69%Forma y color:SolidPeso molecular:558.64Bexarotene
CAS:<p>Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).</p>Fórmula:C24H28O2Pureza:99% - 99.65%Forma y color:White SolidPeso molecular:348.48(R)-4-((5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CAS:Pureza:95%Peso molecular:392.58(3aR,4R,5R,6aS)-Hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl Ester [1,1'-Biphenyl]-4-carboxylic Acid
CAS:<p>Applications Latanoprost Enol is an impurity of Latanoprost (L177280), a prostaglandin analogue used to treat glaucoma and other degenerative diseases of the eye.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993);<br></p>Fórmula:C31H30O5Forma y color:NeatPeso molecular:482.5721-Carboxy Dexamethasone
CAS:<p>Applications 21-Carboxy Dexamethasone is a useful research chemical.<br>References Shepard, Allan R., ACS Chem. Biol., 3, 549-558(2013);<br></p>Fórmula:C22H27FO6Forma y color:White To Off-WhitePeso molecular:406.44Estriol 16a,17b-Diacetate
CAS:Producto controlado<p>Applications Estriol 16α,17β-Diacetate is a diacetate derivative of Estriol (E888960); an estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929); Huffman, et al.: J. Biol. Chem., 169, 167 (1947)<br></p>Fórmula:C22H28O5Forma y color:NeatPeso molecular:372.45Ciclesonide-d11 (Mixture of Diastereomers)
CAS:Producto controlado<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.This compound is a mixture of diastereomers at the cyclohexyl acetal.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Fórmula:C32D11H33O7Forma y color:NeatPeso molecular:551.763-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic Acid Methyl Ester
CAS:Producto controlado<p>Impurity Finasteride EP Impurity B<br>Applications 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester (Finasteride EP Impurity B) is an impurity of Finasteride (F342000) and Dutasteride (D735000). An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.<br>References Bakshi., et al.: J. Med. Chem., 38, 3189 (1995),<br></p>Fórmula:C20H29NO3Forma y color:White To Off-WhitePeso molecular:331.45(16α)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
CAS:Producto controladoFórmula:C24H30O6Forma y color:NeatPeso molecular:414.49Estradiol 3-Valerate
CAS:Producto controlado<p>Applications Estradiols ester used in polymeric matrix for transdermal treatment of osteoporosis.<br>References Tripathi, V.N., et al.: Can. J. Animal Sci., 48, 449 (1968),<br></p>Fórmula:C23H32O3Forma y color:NeatPeso molecular:356.51(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
CAS:Producto controlado<p>Applications (3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate is an intermediate in the synthesis of Prostaglandin E2 (P838610), the most common and biologically potent of mammalian prostaglandins.<br>References Radeuchel, B., et al.: Tetrahedron. Lett., 633, 9 (1975);<br></p>Fórmula:C21H18O5Forma y color:NeatPeso molecular:350.364616-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregn-4-ene-3,11-dione
CAS:Producto controladoFórmula:C24H32O6Forma y color:NeatPeso molecular:416.51rac 7-Methoxy Lasofoxifene
CAS:Producto controlado<p>Applications Lasofoxifene intermediate.<br>References Rosati, R., et al.: J. Med. Chem., 41, 2928 (1998),<br></p>Fórmula:C29H33NO2Forma y color:NeatPeso molecular:427.58(4S,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:Producto controlado<p>Applications An impurity of Atorvastatin.<br>References Graul, A., et al.: Drugs Fut. 22, 956 (1997),<br></p>Fórmula:C14H27NO4Forma y color:NeatPeso molecular:273.3711β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione-d3
Producto controlado<p>Applications A labelled metabolite of Budesonide (B689490), an antiinflammatory agent.<br>References Cserhati, T., et al.: J. Pharm. Biomed. Anal., 22, 25 (2000), Dilger, K., et al.: J. Clin. Pharmacol., 47, 1532 (2007), Buchwald, P., et al.: Steroids, 73, 193 (2008),<br></p>Fórmula:C21H25D3O6Forma y color:NeatPeso molecular:379.466a-Hydroxy Levonorgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity G<br>Applications 6α-Hydroxy Levonorgestrel (Levonorgestrel EP Impurity G) is a hydroxylated impurity of Norgestrel (N689500).<br>References Lin, Y., et al.: Biochim. Biophys. Acta, 218, 526 (1970), Smith, K., et al.: J. Steroid Biochem., 32, 445 (1989), Hu, S., et al.: Steroids, 60, 337 (1995),<br></p>Fórmula:C21H28O3Forma y color:White SolidPeso molecular:328.44Exemestane-13C,D3
CAS:Producto controlado<p>Applications Exemestane-13C,D3 is the labeled analogue of Exemestane (E957000), an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Fórmula:C1913CH21D3O2Forma y color:NeatPeso molecular:300.41(5E)-Calcipotriene
CAS:Producto controlado<p>Impurity Calcipotriol EP Impurity C<br>Stability Temperature Sensitive<br>Applications The trans-isomeric impurity of Calcipotriene (C144200) and a vitamin D3 analogue with antitumor effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wietrzyk, J. et al.: Anti-Cancer Drugs, 18, 447 (2007); Wietrzyk, J. et al.: Anticancer Res., 27, 3387 (2007); Filip, B. et al.: J. Ster. Biochem. Mol. Biol., 121, 399 (2010);<br></p>Fórmula:C27H40O3Forma y color:NeatPeso molecular:412.6013-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol(Levo Norgestrel Impurity)
CAS:Producto controlado<p>Impurity Levonorgestrel EP Impurity C<br>Applications 13-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol (Levonorgestrel EP Impurity C) is an impurity of Levonorgestrel.<br></p>Fórmula:C23H28OForma y color:NeatPeso molecular:320.47Vitamin D3 b-D-Glucuronide, >90%
CAS:Producto controlado<p>Stability Temperature and Light Sensitive<br>Applications A metabolite of Vitamin D3.<br>References Bell, P.A., et al.: Biochem. J., et al.: 115, 663 (1969), Kumar, R.S., et al.: J. Clin. Invest., 65, 277 (1980), Shimada, K., et al.: Biol. Pharm. Bull., 19, 491 (1996),<br></p>Fórmula:C33H52O7Pureza:>90%Forma y color:NeatPeso molecular:560.76∆9,11-Dehydro-17α-cyanomethyl Estradiol
CAS:Producto controlado<p>Applications ∆9,11-Dehydro-17α-cyanomethyl estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.<br>References Oettel, M., et al.: Pharmazie, 41, 627 (1993); Kiley, J. & Shulman, L.: Int. J. Womens Health, 3, 281 (2011);<br></p>Fórmula:C20H23NO2Forma y color:NeatPeso molecular:309.40Dexamethasone acetate monohydrate
CAS:<p>Dexamethasone acetate treats rheumatic issues, skin conditions, asthma, allergies, COPD, brain swelling, croup, TB adjunct.</p>Fórmula:C24H33FO7Forma y color:SolidPeso molecular:452.523-(N-Phenyl-N-methyl)aminoacrolein
CAS:<p>3-(N-Phenyl-N-methyl)aminoacrolein is a hydrophobic compound that has been shown to reversibly bind to serum albumin. This binding leads to a decrease in the lipid content of lipoproteins and a decrease in the rate of their metabolism. These effects are mediated by hydrophobic interactions with the hydrophobic regions of serum albumin. 3-(N-Phenyl-N-methyl)aminoacrolein also interacts with human serum albumin, which is involved in lipid transport and metabolism, and can be used as a contrast agent for X-ray diffraction studies.</p>Fórmula:C10H11NOPureza:Min. 97 Area-%Forma y color:PowderPeso molecular:161.2 g/mol(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
CAS:Fórmula:C24H40O4Pureza:98%Forma y color:SolidPeso molecular:392.58Desogestrel
CAS:Producto controlado<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Fórmula:C22H30OForma y color:White To Off-WhitePeso molecular:310.47(11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione(Deflazacort Impurity)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications (11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, is an impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus.<br>References Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),<br></p>Fórmula:C27H33NO7Forma y color:NeatPeso molecular:483.556α-Hydroxy-21-desacetyl Deflazacort
CAS:Producto controlado<p>Applications The minor metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Fórmula:C23H29NO6Forma y color:NeatPeso molecular:415.48Desisobutyryl Ciclesonide
CAS:Producto controlado<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Fórmula:C28H38O6Forma y color:White To Off-WhitePeso molecular:470.60(5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one
CAS:Producto controlado<p>Applications (5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one is metabolite and impurity of the anabolic steroid Oxandrolone (O845050).<br>References Fragkaki, A.G. et al.: J. Steroid Biochem. Mol. Biol., 115, 44 (2009); Bi, H. et al.: J. Steroid Biochem. Mol. Biol., 42, 533 (1992);<br></p>Fórmula:C19H28O2Forma y color:White To Off-WhitePeso molecular:288.4217β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS:Producto controlado<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Fórmula:C26H31D3O8Forma y color:NeatPeso molecular:477.56Ciclesonide-d7
CAS:Producto controlado<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Fórmula:C32H37D7O7Forma y color:NeatPeso molecular:547.737α-Acetylthio-17α-ethoxymethyl Testosterone
CAS:Producto controladoFórmula:C24H36O4SForma y color:NeatPeso molecular:420.61(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS:Producto controlado<p>Applications Glucocorticoid.<br></p>Fórmula:C22H28O4Forma y color:NeatPeso molecular:356.46Tasimelteon
CAS:<p>Applications Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.<br>References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014);<br></p>Fórmula:C15H19NO2Forma y color:NeatPeso molecular:245.316917a-Hydroxy-17a-methyl-D-homoandrost-4-ene-3,17-dione
CAS:Producto controladoFórmula:C21H30O3Forma y color:NeatPeso molecular:330.469α-Bromobudesonide
CAS:Producto controlado<p>Impurity Budesonide EP Impurity J<br>Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Fórmula:C25H33BrO6Forma y color:NeatPeso molecular:509.43Estradiol 17-Valerate-d9
CAS:Producto controlado<p>Applications Labelled Estradiol (E888000) derivative. An estrogen.<br>References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),<br></p>Fórmula:C23H23D9O3Forma y color:NeatPeso molecular:365.55Estradiol 3-heptanoate
CAS:Producto controladoFórmula:C25H36O3Forma y color:NeatPeso molecular:384.55Testosterone Undecanoate-d21
CAS:Producto controladoFórmula:C30H27D21O3Forma y color:Off-WhitePeso molecular:477.84N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Producto controlado<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Fórmula:C25H38N2O2Forma y color:NeatPeso molecular:398.586b-Hydroxylevonorgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity H<br>Applications 6β-Hydroxylevonorgestrel (Levonorgestrel EP Impurity H) is an impurity from the synthesis of Levonorgestrel (N689510), an oral contraceptive.<br>References Hu. S.H., et al.: Steroids., 63, 88 (1998); Nash, H.A., et al.: J. Pharma. Sci., 93, 2420 (2004); Choudhary, M.I., et al.: Natural. Prod. Res., 20, 1074 (2006);<br></p>Fórmula:C21H28O3Forma y color:White To Light YellowPeso molecular:328.45Fulvestrant 17-Ketone
CAS:Producto controlado<p>Applications Fulvestrant 17-Ketone, is an impurity of Fulvestrant (F862500), a novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).<br>References Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer Res., 61, 6739 (2001),<br></p>Fórmula:C32H45F5O3SForma y color:NeatPeso molecular:604.75Dexamethasone Oxetanone
CAS:Producto controlado<p>Applications Dexamethasone Oxetanone is a potent antiglucocorticoid.<br>References Lamontagne, N., et al.: Endocrinology, 114, 2252 (1984);<br></p>Fórmula:C22H27FO4Forma y color:NeatPeso molecular:374.45[1S-(1α,3aBeta,4β,7aAlpha)]-4-[2-(2,5-Dihydroxyphenyl)ethyl]octahydro-1-hydroxy-7a-methyl-5H-inden-5-one
CAS:Producto controladoFórmula:C18H24O4Forma y color:NeatPeso molecular:304.3817α-Methyl-4-[(phenylthio)methyl]testosterone
CAS:Producto controlado<p>Applications Testosterone (T155000) derivative.<br></p>Fórmula:C27H36O2SForma y color:NeatPeso molecular:424.64Prednisolone 21-Sulfate Sodium Salt
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Prednisolone 21-Sulfate is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Fórmula:C21H27NaO8SForma y color:NeatPeso molecular:462.496-Hydroxymethyl Exemestane
CAS:Producto controlado<p>Applications A potential metabolite of Exemestane (E957000).<br>References Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Fórmula:C20H24O3Forma y color:NeatPeso molecular:312.40Prednicarbate
CAS:Producto controlado<p>Applications Topical anti-inflammatory agent. Glucocorticoid.<br>References Stache, U., et al.: Arzneim.-Forsch., 35, 1753 (1985),<br></p>Fórmula:C27H36O8Forma y color:Off-WhitePeso molecular:488.57(E/Z)-17-Deacetylnorgestimate
CAS:Producto controladoFórmula:C21H29NO2Forma y color:NeatPeso molecular:327.466α-Hydroxy Testosterone-d3
CAS:Producto controladoFórmula:C19H25D3O3Forma y color:NeatPeso molecular:307.4418-Methyl Mestranol
CAS:Producto controlado<p>Applications Mestranol (M258755) derivative. It is used as contraceptive.<br>References Cullen, L.F., et al.: J. Pharma. Sci., 57, 1857 (1968),<br></p>Fórmula:C22H28O2Forma y color:NeatPeso molecular:324.464β-Hydroxy Cholesterol
CAS:Producto controlado<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Fórmula:C27H46O2Forma y color:White To Light BeigePeso molecular:402.651-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one
CAS:Producto controlado<p>Applications 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one is an antioxidant and also has anti cancer effects on human breast cancer MCF-7 cells and Hep3B human hepatocellular carcinoma cells.<br>References Choi, Eun Jeong, et al.: Mol. Med. Rep., 9(1), 328-332 (2014);Choi, Eun Jeong, et al.: Onco.Lett., 6(6), 1784-1788 (2013);Choi, Eun Jeong, et al.: Inter. J.of Mol. Med., 31(3), 726-730 (2013)<br></p>Fórmula:C15H14O4Forma y color:NeatPeso molecular:258.27b-Estradiol 17-Acetate
CAS:Producto controlado<p>Applications Protected Estradiol. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References Miilunpohja, M., et al.: J. Steroid Biochem. Mol. Biol., 100, 59 (2006), Ikonomou, M., et al.: Environ. Toxicol. Chem., 27, 243 (2008),<br></p>Fórmula:C20H26O3Forma y color:NeatPeso molecular:314.42Dexamethasone b-D-Glucuronide Sodium (>90%)
CAS:Producto controlado<p>Applications Sodium salt of Dexamethasone β-D-Glucuronide is a potential prodrug for colonic delivery of the antiinflammatory corticosteroid Dexamethasone.<br>References Fotsis, T., et al.: J. Steroid Biochem., 14, 457 (1981), Choi, M., et al.: Steroids, 65, 54 (2000); Haeberlin, B. et al.: Pharm Res., 10, 1553 (1993);<br></p>Fórmula:C28H36FNaO11Forma y color:NeatPeso molecular:590.57Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS:Fórmula:C22H32FO11PS•xNaForma y color:NeatPeso molecular:554.5222987-(Desacetothioxy)-7-acetodithioperoxy-spironolactone
Producto controladoFórmula:C24H32O4S2Forma y color:NeatPeso molecular:448.6415-Keto Latanoprost
CAS:<p>Applications 15-Keto Latanoprost is a metabolite of Latanoprost (L177280).<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999),<br></p>Fórmula:C23H30O5Forma y color:NeatPeso molecular:386.481,2-Dihydro Triamcinolone
CAS:Producto controlado<p>Applications 1,2-Dihydro Triamcinolone is a derivative of Triamcinolone (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982);<br></p>Fórmula:C21H29FO6Forma y color:NeatPeso molecular:396.45Tixocortol
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.<br>References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),<br></p>Fórmula:C21H30O4SForma y color:NeatPeso molecular:378.533β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS:Producto controladoFórmula:C21H30O2Forma y color:Single SolutionPeso molecular:314.46Dexamethasone 17-Propionate
CAS:Producto controlado<p>Applications A Dexamethasone Dipropionate metabolite.<br>References Miyachi, Y., et al.: Steroids, 52, 137 (1988), Soh H., et al.: Brit. J. dermatol., 125, 73 (1991), Civiale, C., et al.: J. Ocul. Pharmacol., Thera., 20, 75 (2004),<br></p>Fórmula:C25H33FO6Forma y color:NeatPeso molecular:448.52δ6-Gestodene
Producto controlado<p>Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);<br></p>Fórmula:C21H24O2Forma y color:NeatPeso molecular:308.416b-Chloro-17-acetoxy Progesterone
CAS:Producto controlado<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Fórmula:C23H31ClO4Forma y color:NeatPeso molecular:406.9436α-Hydroxy Gestrinone Glucuronide
CAS:Producto controladoFórmula:C27H32O9Forma y color:Light YellowPeso molecular:500.5417α-Hydroxyprogesterone Valerate
CAS:Producto controlado<p>Applications 17α-Hydroxy-progesterone Valerate acts as a synthetic Progesterone (P755900) reducing the chance of pre-term birth in women. Progesterone is a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Fórmula:C26H38O4Forma y color:NeatPeso molecular:414.582,5-Bis(trifluoromethyl)aniline
CAS:Producto controlado<p>Applications 2,5-Bis(trifluoromethyl)aniline is a haloalkul substituted aniline used in the preparation of anti-benign prostatic hyperplasia drug, Dutasteride (D735000).<br>References Liang, Y. et al.: Jil. Dax. Xueb. Lixeub., 45, 1035 (2007);<br></p>Fórmula:C8H5F6NForma y color:ColourlessPeso molecular:229.123-Aminobenzotrifluoride
CAS:Producto controlado<p>Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)<br></p>Fórmula:C7H6F3NForma y color:YellowPeso molecular:161.12Tetrahydrocortisol 21-Acetate
CAS:Producto controlado<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Fórmula:C23H36O6Forma y color:NeatPeso molecular:408.5317α,21-Dideoxy-6α,9α-Difluoroprednisolone
CAS:Producto controlado<p>Applications 17α,21-Dideoxy-6α,9α-Difluoroprednisolone is an impurity of the drug Difluprednate (D445925). Difluprednate is a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002); Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003); Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005)<br></p>Fórmula:C20H24F2O4Forma y color:NeatPeso molecular:366.4(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
CAS:Producto controlado<p>Applications (16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Fórmula:C25H32O6Forma y color:NeatPeso molecular:428.5210b-Hydroxy D-(-)-Norgestrel
CAS:<p>Applications 10β-Hydroxy D-(-)-Norgestrel is an impurity of Levonorgestrel (N689510).<br>References Gorog, S. et al.: J. Pharmac. Biomed. Anal., 14, 85 (1995); Berta, R. et al.: J. Pharmac. Biomed. Anal., 54, 458 (2011); Choudhary, M. I. et al.: Nat. Prod. Res., 20, 1074 (2006);<br></p>Fórmula:C21H28O3Forma y color:White To Off-WhitePeso molecular:328.4457-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β
Producto controlado<p>Applications Fulvestrant (F862500) impurity C.<br></p>Fórmula:C41H65F5O4S2Forma y color:NeatPeso molecular:781.0723-Hydroxybudesonide
CAS:Producto controlado<p>Applications 23-Hydroxybudesonide is an metabolite of budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Edsbaecker, S., et al.: Drug. Metabol. Dispostion., 15, 403 (1987); Moore, C.D., et al.: Drug. Metabolism. Disposition., 41, 379 (2013);<br></p>Fórmula:C25H34O7Forma y color:NeatPeso molecular:446.5320β-Dihydrocortisone
CAS:Producto controlado<p>Applications 20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Reach, G., et. al.: Steroids, 30, 621 (1977); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)<br></p>Fórmula:C21H30O5Forma y color:NeatPeso molecular:362.46(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (Bimatoprost Impurity)
CAS:Producto controladoFórmula:C18H24O4Forma y color:NeatPeso molecular:304.38Ulipristal
CAS:Producto controlado<p>Applications Ulipristal is a selective progesterone receptor modulator. Ulipristal is used as an emergency contraceptive.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>Fórmula:C28H35NO3Forma y color:NeatPeso molecular:433.582-Hydroxy Atorvastatin Lactone
CAS:Producto controlado<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Fórmula:C33H33FN2O5Forma y color:Off White SolidPeso molecular:556.622-Hydroxy Estradiol 6-N3-Adenine
CAS:Producto controlado<p>Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H27N5O3Forma y color:NeatPeso molecular:421.49Fluocinolone Acetonide-13C3
CAS:Producto controladoFórmula:C2113C3H30F2O6Forma y color:NeatPeso molecular:455.472,2-Dibromo-1-(4-fluorophenyl)-2-phenylethanone
Producto controladoFórmula:C14H9Br2FOForma y color:NeatPeso molecular:372.03
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