Esteroides y derivados
Los esteroides son compuestos orgánicos que poseen una estructura de cuatro anillos fusionados, conocida como el núcleo esteroídico. Este núcleo puede unirse a varios grupos funcionales que modifican sus propiedades y funciones biológicas. Los esteroides tienen un papel clave en la regulación de procesos metabólicos y hormonales. Se utilizan en medicina para tratar trastornos inflamatorios, autoinmunes y desequilibrios hormonales. Además, algunos derivados esteroides tienen propiedades antiinflamatorias potentes, como los corticosteroides. En terapias específicas, se usan para reducir la inflamación y controlar el dolor en diversas enfermedades.
En CymitQuimica contamos con una variedad de esteroides y sus derivados para investigación y desarrollo farmacéutico.
Se han encontrado 4964 productos de "Esteroides y derivados"
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Equilin 3-O-β-D-Glucuronide Sodium Salt
CAS:Fórmula:C24H27NaO8Forma y color:NeatPeso molecular:466.4613-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (~90%) (Levo Norgestrel Impurity)
CAS:Producto controlado<p>Impurity Levonorgestrel EP Impurity D<br>Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Fórmula:C21H30OForma y color:NeatPeso molecular:298.464-Hydroxy Estradiol 1-N3-Adenine
CAS:Producto controlado<p>Applications 4-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H27N5O3Forma y color:NeatPeso molecular:421.492-Hydroxy-estrone-6-N3-adenine (90%)
CAS:Producto controlado<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Fórmula:C23H25N5O3Pureza:90%Forma y color:NeatPeso molecular:419.48Epoxy Metradiene
CAS:Producto controlado<p>Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Fórmula:C22H28O4Forma y color:NeatPeso molecular:356.4620-Dihydroprogesterone Acetate
CAS:Producto controlado<p>Impurity Progesterone EP Impurity E<br>Applications 20-Dihydroprogesterone Acetate (Progesterone EP Impurity E) is an analogue of Progesterone (P755900), a steroid used in cardiovascular and menopausal studies.<br>References Grodstein, F. et al.: New. Eng. J. Med., 335, 453 (1996); Cushman, M. et al.: Circulation, 100, 717 (1999);<br></p>Fórmula:C23H34O3Forma y color:NeatPeso molecular:358.51(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:Producto controlado<p>Applications (6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an intermediate in the synthesis of Paramethasone Acetate (P191845), a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Fórmula:C24H29FO6Forma y color:Off-WhitePeso molecular:432.4825-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether
CAS:<p>Applications Vitamin D3 (V676045) analog.<br>References Roy, A., et al.: Steroids, 60, 530 (1995);<br></p>Fórmula:C40H65N3O4SForma y color:NeatPeso molecular:684.03Testosterone-16,16,17-d3 17-Decanoate
CAS:Producto controlado<p>Applications Testosterone 17-Decanoate-d3, is the labeled analogue of Testosterone 17-Decanoate (T155120), an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants.<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Fórmula:C292H3H43O3Forma y color:NeatPeso molecular:445.6917a-Hydroxy-17a-methyl-D-homoandrost-4-ene-3,17-dione
CAS:Producto controladoFórmula:C21H30O3Forma y color:NeatPeso molecular:330.46N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Producto controlado<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Fórmula:C25H38N2O2Forma y color:NeatPeso molecular:398.5818-Methyl Mestranol
CAS:Producto controlado<p>Applications Mestranol (M258755) derivative. It is used as contraceptive.<br>References Cullen, L.F., et al.: J. Pharma. Sci., 57, 1857 (1968),<br></p>Fórmula:C22H28O2Forma y color:NeatPeso molecular:324.464β-Hydroxy Cholesterol
CAS:Producto controlado<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Fórmula:C27H46O2Forma y color:White To Light BeigePeso molecular:402.6517α-Methyl-4-[(phenylthio)methyl]testosterone
CAS:Producto controlado<p>Applications Testosterone (T155000) derivative.<br></p>Fórmula:C27H36O2SForma y color:NeatPeso molecular:424.647α-Acetylthio-17α-ethoxymethyl Testosterone
CAS:Producto controladoFórmula:C24H36O4SForma y color:NeatPeso molecular:420.612,2-Dibromo-1-(4-fluorophenyl)-2-phenylethanone
Producto controladoFórmula:C14H9Br2FOForma y color:NeatPeso molecular:372.03Cholesterol 5α,6α-Epoxide
CAS:Producto controlado<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Fórmula:C27H46O2Forma y color:NeatPeso molecular:402.65Deflazacort-d3 (Major)
CAS:Producto controladoFórmula:C25H28D3NO6Forma y color:NeatPeso molecular:444.544'-Nitro-3'-(trifluoromethyl)acetanilide
CAS:<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Fórmula:C9H7F3N2O3Forma y color:NeatPeso molecular:248.16
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