Sales y derivados de API
Las sales de los Ingredientes Farmacéuticos Activos (API) son compuestos formados por la reacción de un ácido con una base, resultando en un equilibrio iónico. Estas sales suelen mejorar la solubilidad y estabilidad de los APIs, facilitando su absorción en el cuerpo. Los derivados de API son variantes químicas de un principio activo que pueden tener propiedades mejoradas o modificadas para optimizar su eficacia terapéutica. Las sales de APIs se utilizan en la formulación de medicamentos orales, inyectables y tópicos. Además, los derivados de APIs pueden mejorar la farmacocinética de los fármacos, como la liberación controlada de activos.
En CymitQuimica contamos con sales y derivados de APIs con la pureza y calidad necesarias para investigación y desarrollo de formulaciones farmacéuticas.
Se han encontrado 79464 productos de "Sales y derivados de API"
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(3R,4E,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[N-methyl(N-methylsulfonyl)amino]-pyrimidin-5-yl]-3-hydroxy-4,6-heptadienoic Acid Calcium Salt
Fórmula:(C22H25FN3O5S)CaPeso molecular:2(563.5) : 40.08Ro 25-6981 Maleate
CAS:<p>Ro 25-6981 Maleate is an NMDA receptor antagonist used in the study of neurological disorders such as Parkinson's and epilepsy.</p>Fórmula:C26H33NO6Pureza:99.42%Forma y color:SolidPeso molecular:455.54(E)-4-((1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopent-3-en-2-yl)amino)-4-oxobutanoic acid
Fórmula:C24H27NO5Peso molecular:409.48O,O-Dimethyl Methylphosphonate
CAS:Producto controlado<p>Applications O,O-Dimethyl Methylphosphonate is a commercially used preignition additive for gasoline, anti-foaming agent, plasticizer, stabilizer and antistatic agents.<br>References Jang, S.H., et al.: J. Korean. Phy. Soc., 55, 294 (2009); Schneider, B.B., et al.: Int. J. Mass. Spectro., 298, 45 (2010);<br></p>Fórmula:C3H9O3PForma y color:NeatPeso molecular:124.0764'-O-Methylcatechin
CAS:<p>Applications A metabolite of (+)-Catechin, a major polyphenol in many fruits and vegetables.<br>References Heptinstall, S., et al.: J. Cardiovas. Pharmacol., 47, S197 (2006), Gonzalez-Manzano, S., et al.: J. Agric. Food Chem., 57, 1231 (2009), Frank, J., et al.: J. Nut., 139, 58 (2009),<br></p>Fórmula:C16H16O6Forma y color:NeatPeso molecular:304.292-Bromoacetic Acid
CAS:<p>Applications Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);<br></p>Fórmula:C2H3BrO2Forma y color:Light YellowPeso molecular:138.95Pyridin-3-yl Dimethylcarbamate
CAS:Producto controlado<p>Applications Pyridin-3-yl dimethylcarbamate (cas# 51581-32-9) is a useful research chemical.<br></p>Fórmula:C8H10N2O2Forma y color:ColourlessPeso molecular:166.18Scopoline Methobromide
CAS:<p>Applications Scopoline Methobromide is an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator.<br>References Moffett, R.B.. et al.: J. Am. Chem. Soc., 77, 1245 (1955); Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006)<br></p>Fórmula:C9H16NO2·BrForma y color:White To Light GreyPeso molecular:250.13(15R)-Bimatoprost
CAS:<p>Applications An intermediate in the production of Bimatoprost (B386800).<br></p>Fórmula:C25H37NO4Forma y color:NeatPeso molecular:415.57FK-506-13C,D2 (Major) (Tacrolimus) (>85%)
CAS:Producto controladoFórmula:CC43D2H67NO12Pureza:>85%Forma y color:NeatPeso molecular:807.02Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate
CAS:<p>Applications Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Li, X., et. al.: Lett. Org. Chem., 12, 217 (2015); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Fórmula:C13H13NO3SForma y color:NeatPeso molecular:263.31trans-Nerolidol
CAS:Producto controlado<p>Applications Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.<br></p>Fórmula:C15H26OForma y color:NeatPeso molecular:222.37Apixaban-d3
CAS:Producto controlado<p>Applications Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C25H22D3N5O4Forma y color:White To Off-WhitePeso molecular:462.52A77 1726 (E/Z) Mixture
CAS:Producto controlado<p>Impurity Leflunomide USP Related Compound B<br>Applications rac A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective than injectable interferon beta 1a (Rebif®). Leflunomide USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>Fórmula:C12H9F3N2O2Forma y color:NeatPeso molecular:270.21Rivaroxaban-d4
CAS:Producto controladoFórmula:C19H14D4ClN3O5SForma y color:White To Off-WhitePeso molecular:439.91(15R)-Bimatoprost Acid
CAS:Producto controlado<p>Applications (15R)-Bimatoprost Acid is an impurity of the antiglaucoma agent Bimatoprost (B386820). (15R)-Bimatoprost Acid is a metabolically stable analog of PGF2α (P838625) and is a potent agonist for the FP receptor.<br>References Balapure, A.K. et al.: Biochem. Pharmacol., 38, 2375 (1989); Hellberg, M.R. et al.: J. Ocular Pharmacol. Ther., 19, 97 (2003); Krishna, P.M. et al.: J. Pharm. res., 4, 2381 (2011); Resul, B., et al.: J. Med. Chem., 36, 243 (1993)<br></p>Fórmula:C23H32O5Forma y color:NeatPeso molecular:388.497Iopromide
CAS:<p>Applications Nonionic, injectable radio-contrast medium. Diagnostic aid (radiopaque medium).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Muetzel, W., et al.: Am.J. Neuroradiol., 4, 350 (1983), Dawson, P., et al.: Acta Radiol. Diagn., 25, 253 (1984),<br></p>Fórmula:C18H24I3N3O8Forma y color:NeatPeso molecular:791.11N-Demethylivabradine
CAS:Producto controladoFórmula:C26H34N2O5Forma y color:Light Brown To BrownPeso molecular:454.56Riociguat-13C-d3
CAS:Producto controlado<p>Applications Riociguat-13C-d3 is the labelled analogue of Riociguat (R520000), which is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C1913CH16D3FN8O2Forma y color:NeatPeso molecular:426.43Ramipril-d3
CAS:Producto controlado<p>Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Fórmula:C23H29D3N2O5Forma y color:NeatPeso molecular:416.51Trandolapril
CAS:Producto controlado<p>Applications An antihypertensive. Angiotensin converting enzyme (ACE) inhibitor.<br>References Brown, N.L., et al.: Eur. J. Pharmacol., 148, 79 (1988), Kober, L., et al.: N. Engl. J. Med., 333, 1670 (1995), Malik, R.A., et al.: Lancet, 352, 1978 (1998)<br></p>Fórmula:C24H34N2O5Forma y color:NeatPeso molecular:430.54Rivaroxaban Diol
CAS:Producto controlado<p>Applications A metabolite of Rivaroxaban (R538000).<br>References Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005), Roehrig, S., et al.: J. Med. Chem., 48, 5900 (2005), Biemond, B., et al.: Thromb. Haemost., 97, 471 (2007), Lang, D., et al.: Drug Metab. Dispos., 37, 1046 (2009),<br></p>Fórmula:C19H20ClN3O6SForma y color:White To Off-WhitePeso molecular:453.9Ramipril-d5
CAS:Producto controlado<p>Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>Fórmula:C23H27D5N2O5Forma y color:WhitePeso molecular:421.54Riociguat
CAS:Producto controlado<p>Applications Riociguat is used in the treatment for pulmonary hypertension.<br>References Frey, R. et al.: J. Clin. Pharmacol., 51, 1051 (2011);<br></p>Fórmula:C20H19FN8O2Forma y color:NeatPeso molecular:422.4157S-(-)-Warfarin
CAS:Producto controlado<p>Applications The S-(-)-form of Warfarin (W498500). Coumarin anticoagulant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hagan, E.C., et al.: J. Am. Pharm. Assoc. Sci. Ed., 42, 379 (1953), Bell, R.G., et al.: Biochemistry, 11, 1959 (1972), Valente, J.E., et al.: J. Med. Chem., 20, 1489 (1977), Back, N., et al.: Pharmacol. Res. Commun., 10, 445, (1978), Babhair, S.A., et al.: Anal. Profiles Drug Subs., 14, 423 (1985), Takahashi, H., et al.: Echizen, Clin. Pharmacokinet., 40, 587 (2001),<br></p>Fórmula:C19H16O4Forma y color:White SolidPeso molecular:308.33Ethyl 2-Chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
CAS:Producto controlado<p>Applications Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (cas# 27143-07-3) is a useful research chemical.<br></p>Fórmula:C11H13N2O3ClForma y color:NeatPeso molecular:256.68Ethyl-S-(+)-Clopidogrel Sulfate
CAS:Producto controlado<p>Stability Very Hygroscopic<br>Applications Ethyl-(S)-(+)-Clopidogrel Sulfate is an analogue of S-(+)-Clopidogrel Hydrogen Sulfate (C587250) which is used as an antithrombotic.<br>References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)<br></p>Fórmula:C17H20ClNO6S2Forma y color:White To Off-WhitePeso molecular:433.934-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol
CAS:Producto controlado<p>Applications 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Asaki, T., et al.: Bioorg. Med. Chem., 15, 6692 (2007); Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Fórmula:C23H27N3OForma y color:NeatPeso molecular:361.483-((2-Chloroethyl)amino)propyl Dihydrogen Phosphate
CAS:Producto controlado<p>Impurity Ifosfamide EP Impurity A<br>Applications 3-((2-Chloroethyl)amino)propyl Dihydrogen Phosphate is a metabolite of Ifosfamide (I265000), which is a cytostatic drug.<br>References Gilard, V., et al.: J. Med. Chem., 42, 2542 (1999);<br></p>Fórmula:C5H13ClNO4PForma y color:WhitePeso molecular:217.59Brinzolamide
CAS:Producto controlado<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Fórmula:C12H21N3O5S3Forma y color:NeatPeso molecular:383.51Diclofenac Levomenthol Ester
CAS:Producto controladoFórmula:C24H29Cl2NO2Forma y color:NeatPeso molecular:434.399Tolvaptan
CAS:Producto controlado<p>Applications Tolvaptan is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006);<br></p>Fórmula:C26H25ClN2O3Forma y color:White To Off-WhitePeso molecular:448.94Riluzole-13C,15N2
CAS:Producto controladoFórmula:C713CH5F315N2OSForma y color:Light Beige To Light YellowPeso molecular:237.18Riluzole
CAS:<p>Applications A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. Neuroprotective agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mizoule, J., et al.: Neuropharmacology, 24, 767 (1985), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)<br></p>Fórmula:C8H5F3N2OSForma y color:NeatPeso molecular:234.20
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