Sulfonamidas y derivados
Las sulfonamidas son compuestos que contienen un grupo funcional sulfonamida (-SO₂NH₂), en el que un átomo de azufre está unido a un grupo amino. Fueron de los primeros antibióticos sintéticos utilizados en medicina, inhibiendo la síntesis de ácido fólico en bacterias, lo que les confiere propiedades antimicrobianas. Se utilizan principalmente para tratar infecciones bacterianas, aunque hoy en día su uso se ha visto reducido debido a la resistencia antimicrobiana. Además de su uso en antibióticos, las sulfonamidas también tienen aplicaciones en el tratamiento de enfermedades como la malaria y enfermedades inflamatorias intestinales.
En CymitQuimica ofrecemos sulfonamidas y sus derivados con alto grado de pureza para investigación en microbiología y desarrollo farmacéutico.
Se han encontrado 2589 productos de "Sulfonamidas y derivados"
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2-Chloronicotinic Acid
CAS:Producto controlado<p>Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.<br>References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);<br></p>Fórmula:C6H4ClNO2Forma y color:NeatPeso molecular:157.55N-Desbutyl-N-propyl Bumetanide
CAS:Producto controlado<p>Applications Bumetanide (B689550) analogue as diuretic and antihypertensive. Bumetanide impurity.<br>References Feit, P.W., et al.: J. Med. Chem., 14, 432 (1971),<br></p>Fórmula:C16H18N2O5SForma y color:NeatPeso molecular:350.3894-desamino Dapsone
CAS:<p>Applications 4-Phenylsulfonylaniline is used in the preparation of novel Flufenamic acid analogues as inhibitors of androgen receptor mediated transcription.<br>References Kemppainen, J., et al.: J. Biol. Chem., 267, 968 (1992), Amler, L., et al.: Cancer Res., 60, 6134 (2000), Klotz, L., et al.: Clin. Prostate Cancer, 3, 215 (2005),<br></p>Fórmula:C12H11NO2SForma y color:White To Off-WhitePeso molecular:233.293-Hydroxyacetaminophen-D3
CAS:Producto controlado<p>Applications 3-Hydroxyacetaminophen-d3 is deuterium labeled 3-Hydroxyacetaminophen (H714750). 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)<br></p>Fórmula:C82H3H6NO3Forma y color:NeatPeso molecular:170.18N-(2,3-Dimethylphenyl) Mefenamic Acid Carboxamide
CAS:Producto controlado<p>Impurity Mefeneic Acid EP Impurity B<br>Applications N-(2,3-Dimethylphenyl) Mefenamic Acid Carboxamide is a derivative of Mefenamic Acid (M205050); an anti-inflammatory agent and analgesic.<br>References Winder, C.V., J. Pharmacol. Exp. Ther., 138, 405 (1962)<br></p>Fórmula:C23H24N2OForma y color:NeatPeso molecular:344.454-(2-Aminoethyl)benzenesulfonamide
CAS:Producto controladoFórmula:C8H12N2O2SForma y color:NeatPeso molecular:200.26Zonisamide N,N-Dimethylformimidamide
CAS:<p>Applications Zonisamide related compound C.<br></p>Fórmula:C11H13N3O3SForma y color:White To Off-WhitePeso molecular:267.30Acemetacin
CAS:Producto controlado<p>Applications Acemetacin is a non-steroidal anti-inflammatory agent and used to treat rheumatic disease and other musculoskeletal disorders (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Jacobi, H. and Dell, H. D.: Arzneimittelforschung 30, 1398 (1980) (2) Moore, R. A., et al.: Cochrane Database Syst Rev. 8,CD007589 (2009)<br></p>Fórmula:C21H18ClNO6Forma y color:YellowPeso molecular:415.82Sulfadiazine-d4
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications The isotopically labelled drug Sulfadiazine. Antibacterial.<br>References Bohni, et al.: Chemotherapy, 14, 195 (1969), Carr, et al.: Antimicrob. Agents Chemother., 4, 585 (1973), Stober, H., et al.: Anal. Profiles Drug Subs., 11, 523 (1982),<br></p>Fórmula:C10D4H6N4O2SForma y color:Light YellowPeso molecular:254.35-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine
CAS:<p>Stability Hygroscopic<br>Applications 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a derivative of Trimethoprim (T795615), an antibacterial agent. 5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine, is a possible potent and selective inhibitor targeting dihydrofolate reductase of C. hominis, used for the treatment of Cryptosporidiosis.<br>References Popov, V. M., et al.: Bioorg. Med. Chem. Lett., 16, 4366 (2006); Brogden, R.N., et al.: Drugs, 23, 405 (1982);<br></p>Fórmula:C14H16N4O4Forma y color:Light Yellow To OrangePeso molecular:304.30Sulfasalazine
CAS:Producto controlado<p>Applications Sulfasalazine is an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis.<br>References Schroder, H., et al.: Clin. Pharmacol. Ther.,13, 539 (1972), McDonnell, J.P., et al.: Anal. Profiles Drug Subs., 5, 515 (1976), Klotz, U., et al.: Clin. Pharmacokinet.,10, 285 (1985),<br></p>Fórmula:C18H14N4O5SForma y color:Yellow To Dark OrangePeso molecular:398.394-Carboxy-a-methylbenzeneacetic Acid
CAS:Producto controladoFórmula:C10H10O4Forma y color:WhitePeso molecular:194.18Sulfamonomethoxine-d4
CAS:Producto controlado<p>Applications Labelled Sulfamonomethoxine. Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.<br>References Bridges, et al.: Biochem. J., et al.: 96, 829 (1965), Hong, Y.-L., et al.: Antimicrob. Agents Chemother., 39, 1756 (1995)<br></p>Fórmula:C11H8D4N4O3SForma y color:NeatPeso molecular:284.33Mefenamic Acid-d3 (major)
CAS:Producto controladoFórmula:C15H12D3NO2Forma y color:Light YellowPeso molecular:244.32-Phenoxylaniline
CAS:Producto controlado<p>Impurity Nimesulide EP Impurity C<br>Stability Hygroscopic<br>Applications 2-Phenoxylaniline (Nimesulide EP Impurity C) is an impurity of Nimesulide (N477500) which is an antiinflammatory agent that preferentially inhibits COX-2 over COX-1.<br>References Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)<br></p>Fórmula:C12H11NOForma y color:Off-WhitePeso molecular:185.22Sulfachlorpyridazine-d4
CAS:Producto controlado<p>Applications Labelled analogue of Sulfachlorpyridazine, an antibacterial compound.<br>References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);<br></p>Fórmula:C10H5D4ClN4O2SForma y color:NeatPeso molecular:288.754-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
CAS:<p>Applications An impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Fórmula:C21H16Cl2N2O3Forma y color:NeatPeso molecular:415.27p-Butyl Ibuprofen
CAS:Producto controlado<p>Applications p-Butyl Ibuprofen (cas# 3585-49-7) is a useful research chemical.<br></p>Fórmula:C13H18O2Forma y color:Light YellowPeso molecular:206.28Xipamide-d6
CAS:Producto controlado<p>Applications A labelled diuretic and antihypertensive.<br>References Wagieh, N., et al.: Drug Test. Anal., 2, 113 (2010), Prado-Prado, F., et al.: Bioorg. Med. Chem., 18, 2225 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Fórmula:C15H9D6ClN2O4SForma y color:NeatPeso molecular:360.854-Nitroso Sulfamethoxazole, > 90%
CAS:Producto controlado<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Fórmula:C10H9N3O4SPureza:>90%Forma y color:NeatPeso molecular:267.26Limaprost-d3 (>90%)
CAS:Producto controlado<p>Applications Labelled Limaprost (L461500). Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Fórmula:C22H33D3O5Pureza:>90%Forma y color:NeatPeso molecular:383.54N-Acetyl Sulfamethoxazole
CAS:<p>Impurity Sulfamethoxazole EP Impurity A<br>Applications A metabolite of Sulfamethoxazole.<br>References Ciolino, H., et al.: Cancer Res., 58 , 2754 (1998), Larsen, T., et al.: Environ. Sci. Technol., 35, 192 (2001), Heberer, T., et al.: Toxicol. Lett., 131, 5 (2002), Larsen, T., et al.: J. Biotechnol., 113, 295 (2004),<br></p>Fórmula:C12H13N3O4SForma y color:Off-WhitePeso molecular:295.31Mefruside
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Mefruside is a diuretic used for the treatment of edema and hypertension.<br>References Johansen, A., et al.: Euro. J. Epidemiol., 27, 63 (2012); Hasegawa, Y., et al.: Blood. Press. Supple., 1, 10 (2010);<br></p>Fórmula:C13H19ClN2O5S2Forma y color:Off-WhitePeso molecular:382.88Ibuprofen Related Compound (2,3-Dihydroxypropyl 2-(4-Isobutylphenyl)Propanoate)
CAS:Producto controlado<p>Applications Ibuprofen Related Compound is used for research purposes on Ibuprofen soft capsules for the investigation of unknown impurities.<br>References Bao, S., et al.: Yaowu Fenxi Zazhi, 35, 97 (2015)<br></p>Fórmula:C16H24O4Forma y color:ColourlessPeso molecular:280.36Ethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide(Piroxicam Impurity H)
CAS:Producto controlado<p>Impurity Piroxicam EP Impurity H<br>Applications Piroxicam Impurity H.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Fórmula:C11H11NO5SForma y color:White To Off-WhitePeso molecular:269.271,3-Dipalmitoyl-2-chloropropanediol-d5
CAS:Producto controlado<p>Applications Labelled 1,3-Dipalmitoyl-2-chloropropanediol is used in the synthesis of some prodrugs of Piroxicam and Lornoxicam to improve their bioavailability.<br>References Passarotti, C.M., et al.: Bollettino Chimico Farmaceutico, 134, 161 (1995),<br></p>Fórmula:C352H5H62ClO4Forma y color:WhitePeso molecular:592.39Hydrochlorothiazide-d2
CAS:Producto controlado<p>Applications Hydrochlorothiazide-d2 is the labeled analogue of Hydrochlorothiazide (H714560), a carbonic anhydrase inhibitor as a diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961); Deppeler, H.P., et al.: Anal. Profiles Drug Subs., 10, 405 (1981)<br></p>Fórmula:C72H2H6ClN3O4S2Forma y color:WhitePeso molecular:299.752-(p-Tolyl)propionic Acid
CAS:Producto controlado<p>Impurity Ibuprofen EP Impurity D<br>Applications 2-(p-Tolyl)propionic acid (Ibuprofen EP Impurity D) is an impurity of Ibuprofen (I140000). Ibuprofen impurity D.<br>References Jia, C., et al.: Science, 287, 1992 (2000), Yu, J., et al.: Org. Biomol. Chem., 4, 4041 (2006),<br></p>Fórmula:C10H12O2Forma y color:White To Off-WhitePeso molecular:164.20N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide
CAS:Producto controlado<p>Impurity Acetazolamide EP Impurity A<br>Applications N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide is an impurity of Acetazolamide (A161500). Acetazolamide EP Impurity A<br>References Zarghi, A., et al.: J. Pharm. Biomed. Anal., 28, 169 (2002), Subbarao, D., et al.: J. Chromatogr., 67, 841 (2008),<br></p>Fórmula:C4H4ClN3OSForma y color:White To Off-WhitePeso molecular:177.61Descyclohexylformamide Glipizide
CAS:Producto controlado<p>Impurity Glipizide EP Impurity D<br>Applications 4-[β-(6-Methylpyrazinyl-2-carboxamido)ethyl]benzene Sulfonamide (Glipizide EP Impurity D) is an intermediate in the synthesis of the impurity 5-Desmethyl-6-methyl Glipizide (D292550).<br></p>Fórmula:C14H16N4O3SForma y color:NeatPeso molecular:320.37Acetazolamide-d3
CAS:Producto controlado<p>Applications Carbonic anhydrase inhibitor. Diuretic.<br>References Parasrampuria, J., et al.: Anal. Profiles Drug Subs. Excip. 22, 1 (1993),<br></p>Fórmula:C4H3D3N4O3S2Forma y color:Off White To Light YellowPeso molecular:225.26Acetaminophen-d3
CAS:Producto controlado<p>Applications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C82H3H6NO2Forma y color:WhitePeso molecular:154.18Sulfadimethoxine-d4
CAS:Producto controlado<p>Applications Sulfadimethoxine-d4 is a isotope labeled version of Sulfadimethoxine (S699060), a sulfonamide antibiotic.<br>References Seki, et al.: Arzneim.-Forsch., 15, 1441 (1965), Bohni, et al.: Chemotherapy, 14, 195 (1969),<br></p>Fórmula:C12H10D4N4O4SForma y color:NeatPeso molecular:314.35Acetaminophen-d4 (major)
CAS:Producto controlado<p>Applications Acetaminophen-d4 (major) is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)(3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C82H4H5NO2Forma y color:Off-WhitePeso molecular:155.19rac-Acetaminophen Mercapturate-d5 (Major)
CAS:Producto controlado<p>Applications rac-Acetaminophen Mercapturate-d5 (Major), is a labeled analogue and free acid of 3-(N-Acetyl-L-cystein-S-yl) Acetaminophen Disodium Salt (A172100), which is a metabolite of Acetaminophen (A161220). Acetaminophen is an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References van der Hooft, J.,et al.: Metabolomics, 12, 1 (2016)<br></p>Fórmula:C13H11D5N2O5SForma y color:NeatPeso molecular:317.37Hydrochlorothiazide Dimer
CAS:<p>Impurity Hydrochlorothiazide EP Impurity C<br>Applications N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide (Hydrochlorothiazide EP Impurity C) is an impurity in bulk Hydrochlorothiazide. Dimer Impurity C.<br>References Daniels, S.L., et al.: J. Pharm. Sci., 70, 211 (1981), Fang, X., et al.: Pharm. Res., 14, 691 (1997),<br></p>Fórmula:C15H16Cl2N6O8S4Forma y color:Off-WhitePeso molecular:607.498-Methyl Etodolac
CAS:Producto controlado<p>Impurity Etodolac EP Impurity B<br>Applications 8-Methyl Etodolac (Etodolac EP Impurity B) is an impurity of Etodolac (E933100) which was examined for mutagenicity in reverse mutation tests on bacteria. Etodolac impurity B.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>Fórmula:C16H19NO3Forma y color:WhitePeso molecular:273.334-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride
CAS:<p>Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.<br>References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)<br></p>Fórmula:C14H13ClN2O2·HClForma y color:NeatPeso molecular:313.18Sulfadiazine Sodium Salt
CAS:Producto controlado<p>Applications Sulfadiazine Sodium Salt can be used as reactant/reagent in preparation and crystal structure of aminophenyl sulfonamide tetrahalides, hydrochloride and hydrobromide cocrystals with iodine.<br>References Pan, F., et al.: CrystEngComm, 17, 6641 (2015)<br></p>Fórmula:C10H9N4NaO2SForma y color:Off-WhitePeso molecular:272.264-Deschloro-4-(2-furanylmethyl)amino Furosemide
CAS:<p>Impurity Furosemide EP Impurity D<br>Applications 4-Deschloro-4-(2-furanylmethyl)amino Furosemide (Furosemide EP Impurity D) is a Furosemide (F865000) Impurity.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979)<br></p>Fórmula:C17H17N3O6SForma y color:White To Dark BrownPeso molecular:391.405-Amino-1,3,4-thiadiazol-2-sulfonamide
CAS:Producto controladoFórmula:C2H4N4O2S2Pureza:99%Forma y color:NeatPeso molecular:180.21N-Acetyl Sulfadiazine
CAS:Producto controladoFórmula:C12H12N4O3SForma y color:Off-WhitePeso molecular:292.313-(p-Chlorophenyl)-3-hydroxyphthalimidine
CAS:Producto controlado<p>Applications 3-(p-Chlorophenyl)-3-hydroxyphthalimidine is an analog of Chlorthalidone (C427500) and has potential antidiuretic and hyperglycemic activities.<br>References Wales, J.K., et al.: P. Soc. Exp. Biol. Med., 128, 581 (1968)<br></p>Fórmula:C14H10ClNO2Forma y color:White To Off-WhitePeso molecular:259.69rac cis-3-Hydroxy Glyburide
CAS:Producto controlado<p>Applications rac cis-3-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic (MII-metabolite).<br>References Heptner, W., et al.: Pharmaceut. Res., 5, 215 (1984), Rydberg, T., et al.: Br. J. Clin. Pharm., 43, 373 (1997),<br></p>Fórmula:C23H28ClN3O6SForma y color:NeatPeso molecular:510.00rac Indapamide-d3
CAS:Producto controlado<p>Applications Labelled Indapamide. Used as an antihypertensive. Diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Fórmula:C16H13D3ClN3O3SForma y color:White To Light Orange ColorPeso molecular:368.858-Methylquinoline
CAS:<p>Applications 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.<br>References Smith, C. J., et al.: Mutat. Res., Fund. Mol. Mech. Mut., 379, 167 (1997)<br></p>Fórmula:C10H9NForma y color:Light Yellow LiquidPeso molecular:143.1854’-Hydroxyacetophenone Oxime
CAS:Producto controlado<p>Impurity Paracetamol EP Impurity G<br>Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Fórmula:C8H9NO2Forma y color:NeatPeso molecular:151.16
