2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol Hydrochloride

CAS: 1033719-36-6

Ref. TR-M287210

Información del producto

• Nombre: 2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol Hydrochloride
• Sinónimos: Duloxetine EP Impurity E
• Marca: TRC

Descripción

Impurity Duloxetine EP Impurity E
Stability Hygroscopic
Applications 2-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol (Duloxetine EP Impurity E) is an impurity of Duloxetine (D721000), a dual serotonin and norepinephrine reuptake inhibitor (SNRI) used in treatment of stress urinary incontinence.
References Arava, V.R., et al.: Ind. J. Chem. Org. Chem. Med. Chem., 46, 1695 (2007); Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)

Propiedades químicas

• Peso molecular: 297.423646
• Fórmula: C₁₈H₁₉NOS•HCl
• Color/Forma: Neat
• InChI: InChI=1S/C18H19NOS.ClH/c1-19-11-10-15(17-7-4-12-21-17)16-9-8-13-5-2-3-6-14(13)18(16)20;/h2-9,12,15,19-20H,10-11H2,1H3;1H