Entre las marcas de nuestros más de 25 colaboradores destaca TargetMol

<p>A unique collection of xnum compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；</p>

A unique collection of xnum ubiquitination related small chemicals can be used for high throughput and high content screening；

<p>A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；</p>

<p>TargetMol’s Cuproptosis Compound Library is a collection of xnum compounds related to copper-dependent death that can be used to study its mechanism and related</p>

<p>xnum types of active small molecules associated with pyroptosis for high-throughput and high-content screening.</p>

<p>1119 drug fragments，a must-have tool for FBDD;</p>

<p>A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;</p>

<p>425 food additives;</p>

<p>A collection of xnum bitter compounds, suitable for high-throughput and high-content screening;</p>

<p>Feed additives are a core component of the modern feed industry. They refer to small or trace substances added during the processing and application of feed. Although the dosage is extremely small (usually less than 1%), they play a significant role in enhancing feed nutrition, improving animal production performance, safeguarding animal health, optimizing the quality of livestock products and reducing breeding costs. TargetMol has collected 256 types of feed additives, which can be applied in feed development and other research fields.</p>

<p>A collection of 79 phosphatase inhibitors with known activity;</p>

<p>A unique collection of xnum approved and clinical drugs for high throughput screening (HTS) and high content screening (HCS);</p>

<p>A unique collection of 972 pediatric drugs for high-throughput screening and high-content screening.</p>

<p>A unique collection of xnum compounds for high-throughput screening and high-content screening,</p>

A unique collection of xnum pesticide-related compounds for high throughput screening (HTS) and high content screening (HCS);

<p>xnum macrocyclic compounds of known activity for high-throughput, high-content screening;</p>

<p>A unique collection of xnum PPI-related compounds for drug screening;</p>

<p>A unique collection of 1920 covalent Inhibitors and other molecules with common warheads like chloroacetyl，2-Chloropropionyl，Acryloyl，sulfonyl fluoride, alkyne，</p>

The cysteine covalent library contains xnum compounds.

<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>

A unique collection of xnum annotated bioactive compounds with clear targets, suitable for phenotypic screening；

<p>A unique collection of xnum types of multi-target compounds for high throughput screening (HTS) and high content screening (HCS);</p>

<p>791 peptides can be used in peptide drug development and signaling transduction and mechanism study;</p>

<p>55 species of cyclic peptide molecules for high-throughput and high-content screening;</p>

<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>

<p>The library contains 4,775 CRBN-based molecular glue compounds with molecular weights ranging from 250 to 550 Da.</p>

<p>A unique collection of xnum potential anti-fibrosis compounds, can be used in HTS and HCS;</p>

<p>A unique collection of 97 beta-lactam compounds, can be used in HTS and HCS;</p>

<p>A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.</p>

<p>A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.</p>

<p>A unique collection of xnum of orally active compounds for high-throughput screening and high-content screening.</p>

<p>1163 compounds associated with depression that can be used for high-throughput and high-content screening</p>

<p>A Collection of xnum inactive ingredients from FDA-approved drugs.</p>

<p>A unique collection of xnum of cosmetic ingredient compounds.</p>

<p>A collection of 195 Baijiu components, suitable for high-throughput and high-content screening.</p>

<p>Vitamins are a class of trace organic small molecules essential for maintaining normal life activities in the human body. Most of them cannot be synthesized by the body itself or the synthesis amount is insufficient, and must rely on external intake. Vitamins do not provide energy and do not form cell structure, but as key metabolic regulatory substances, they play irreplaceable physiological functions in the body: for example, B vitamins act as coenzymes to participate in energy and material metabolism; Vitamin C has a powerful antioxidant effect and promotes the synthesis of collagen. Vitamin A maintains visual and immune functions; Vitamin D regulates calcium-phosphorus balance and bone health. Vitamin E protects cell membranes from oxidative damage. Vitamin K plays a core role in blood coagulation and bone metabolism. TargetMol includes 90 kinds of natural vitamins and their derivatives and analogues. All compounds have undergone strict quality control, with high purity and detailed information, and are provided in standardized formats. It is an effective tool resource for promoting research in the field of vitamins and related areas, facilitating the development of new drugs, exploration of disease mechanisms, and innovation of functional products.</p>

The library consists of more than 4,000 members belonging 22 scaffolds (average 180 compounds per scaffold).

<p>3-Methylxanthine inhibits GMP &amp; xanthine crystallization; IC50 of 920 μM in guinea-pig trachealis; may prevent renal calculi in xanthinuria.</p>

<p>4-Hydroxycoumarin: precursor to 4HC anticoagulants like warfarin; has anticoagulant, antibacterial, antiviral, and anticancer properties.</p>

Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound PDK0044, with CAS No. 1205-30-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0044 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

<p>Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.</p>

Compound PDK0095, with CAS No. 1777-82-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0095 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Methylcinnamic acid is a cinnamic acid analog that can be used as an intervention catalyst to overcome antifungal tolerance.

<p>Compound PDK0106, with CAS No. 19395-41-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0106 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>Compound PDK0269, as 5-HT3 receptor agonists(3–100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.</p>

<p>Compound PDK0270, with CAS No. 551-16-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0270 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

<p>Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>

Compound PDK0318, with CAS No. 645-33-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0318 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound PDK0326, with CAS No. 6631-94-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0326 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

<p>Methylsyringol is a natural product from Pinus yunnanensis.</p>

Compound PDK0375, with CAS No. 84504-69-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0375 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>

Compound PDK0420, with CAS No. 99-05-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0420 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

<p>Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.</p>

Iron(II) fumarate (Iron Fumarate) is the iron(II) salt of fumaric acid, a reddish-orange powder, applied to supply iron intake.

Ethamsylate (Dicynene) 通常用作止血药，增加毛细血管内皮阻力和血小板粘附，抑制前列腺素的生物合成和作用。

<p>Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.</p>

Salicylamide (2-Hydroxybenzamide) is an over-the-counter drug with analgesic and antipyretic properties, which has similar medicinal properties to aspirin.

Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.

<p>Dark green, bronze-lustered Methylene Blue trihydrate is a deep blue dye in water/alcohol, used in staining, cyanide treatment, and methemoglobin reduction.</p>

Atenolol (Tenormin) is a selective β1 receptor antagonist.

<p>(R)-(+)-Atenolol ((R)-Atenolol) is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.</p>

Atenolol Hydrochloride is a selective antagonist of ß1 receptor.

Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .

<p>Flubendazole (Flumoxane) is available OTC in Europe that is an anthelmintic using to treat worm infection in humans.</p>

6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.

2-Phenylethanol (Phenylethanol) is an antimicrobial, antiseptic, and disinfectant.

Cinchonine (LA40221), a potent amide local anesthetic for surface use, is toxic and limited to spinal anesthesia.

<p>Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.</p>

Anethole (Anise camphor) is a type of aromatic compound that exists widely in nature, widely utilized as a seasoning substance.

<p>Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.</p>

Mexenone (Uvistat) is a benzophenone-derived sun protection.

Phenolphthalein (Phthalin): Colorless in acid, turns pink-red in alkaline solutions. Used as acid-base indicator and cathartic.

Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog

Betaine chloride (Betaine hydrochloride) gains the amplification of DNA by decreasing the formation of secondary structure in GC-rich regions.

Sodium 4-aminosalicylate dihydrate (4-Amino-salicylic acid sodium salt) is the sodium salt form of aminosalicylic acid, an analog of para-aminobenzoic acid (

<p>Taurine (2-Aminoethanesulfonic acid) is an organic acid widely distributed in animal tissues and is one of the constituents of bile acids. Cost-effective and quality-assured.</p>

<p>Valethamate bromide (Resitan) is an anticholinergic agent that has antispasmodic effects and inhibits glandular secretion.</p>

Primidone (NCI-C56360) is a potent anticonvulsant agent.

Haloperidol (Serenace) is a highly potent neuroleptic by relieving nervous through the depression of nerve function.

<p>Sulfalene (SMP2), a long-acting sulfonamide antibiotic, is used for the therapy of chronic bronchitis, urinary tract infections, and malaria.</p>

Octisalate is a colorless, floral-scented ester used in sunscreens to absorb UVB rays.

<p>Gamibetal (4-Amino-3-hydroxybutyric Acid) is used as a chiral reagent in the synthesis of antiepileptic and hypotensive drug GABOB and analogues.</p>

<p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>

Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.

Bupivacaine (AH-250) is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels

<p>Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic</p>

<p>Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic</p>

<p>Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.</p>

DL-Xylose ((±)-Xylos) is a sugar first derived from wood. DL-Xylose is classified as a monosaccharide of the aldopentose type.

<p>Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.</p>

Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and

Dienestrol (Restrol) is a synthetic and nonsteroidal estrogen, which is an estrogen receptor agonist.

18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-inflammatory and antiproliferative properties.

Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.

Doxapram hydrochloride hydrate (Doxapram HCl) inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 0.41, 37, 9 μM, respectively.

<p>Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.</p>

Quinestrol (Ethinylestradiol 3-cyclopentyl ether) is a synthetic estrogen, applied in hormone replacement therapy, and occasionally to use in cancer and

<p>Xylometazoline hydrochloride (Xylometazoline HCl) is an α-adrenoceptor agonist usually used as nasal decongestant.</p>

<p>Octodrine (2-Amino-6-methylheptane) is primarily used as a pharmaceutical intermediate for Octamylamine; it also functions as a local anesthetic and vasoconstrictor.</p>

Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain.

<p>Heptaminol hydrochloride (RP-2831 hydrochloride), a vasoconstrictor, is used in the therapy of hypotension, especially orthostatic hypotension.</p>

Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of end

<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>

<p>Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.</p>