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Rapamycine

CAS 53123-88-9: Rapamycine

Description :Rapamycine, également connu sous le nom de sirolimus, est un composé macrolide avec le numéro CAS 53123-88-9. Il est produit par la bactérie *Streptomyces hygroscopicus* et est principalement connu pour ses propriétés immunosuppressives, ce qui le rend précieux dans la transplantation d'organes pour prévenir le rejet. Rapamycine fonctionne en inhibant la cible mammifère de Rapamycine (mTOR), un régulateur clé de la croissance cellulaire, de la prolifération et de la survie. Cette inhibition entraîne une réduction de l'activation et de la prolifération des cellules T. En plus de ses effets immunosuppresseurs, Rapamycine a attiré l'attention pour ses potentielles propriétés anticancéreuses et son rôle dans la promotion de la longévité chez divers organismes modèles. Le composé est généralement administré par voie orale et a une demi-vie relativement longue, permettant des effets thérapeutiques soutenus. Cependant, il peut avoir des effets secondaires, notamment un risque accru d'infections, des troubles métaboliques et une toxicité pulmonaire potentielle. En raison de sa pharmacocinétique complexe, le suivi des niveaux sanguins est souvent nécessaire pour optimiser le dosage et minimiser les effets indésirables.

Formule :C51H79NO13

InChI :InChI=1/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12-,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38?,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1

Code InChI :InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N

SMILES :O=C1OC(CC(=O)C(C=C(C)C(O)C(OC)C(=O)C(C)CC(C=CC=CC=C(C)C(OC)CC2OC(O)(C(=O)C(=O)N3CCCCC13)C(C)CC2)C)C)C(C)CC4CCC(O)C(OC)C4

  • Synonymes :
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15Z,17E,19E,21S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • 14S-Rapamycin
  • 23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-(3-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-, (3S-(3R*S*1R*,3S*,4S*)),6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*))-
  • 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine, rapamycin deriv.
  • 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-, [3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • Antibiotic AY 22989
  • Voir d'autres synonymes
  • Ay 22989
  • Cypher
  • Cypher Bx Velocity
  • De 109
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • Ms-Ro01
  • Ms-Ro02
  • Ms-Ro03
  • Nab rapamycin
  • Nsc 226080
  • PNP-sirolimus
  • Perceiva
  • RPM
  • Rapa
  • Rapammune
  • Rapamune
  • Rapamycin
  • Rapamysin
  • Siia 9268A
  • Supralimus
  • Svp-R
  • Wy 090217
  • [3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
  • (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-
  • Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-imethoxy-
  • 6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
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17 produitstrouvés.

MarqueInformations sur le produitDegré de puretéGamme de prixLivraison estimée
TCI logo
Rapamycin
REF : 3B-R0097CAS : 53123-88-9 		>98.0%(HPLC)83,00 €lun 07 Avr 25
Alfa Aesar By Thermo Fisher Scientific logo
Rapamycin, 98+%
REF : 02-J62473CAS : 53123-88-9 		98+%179,00 €~288,00 €mar 08 Avr 25
Fluorochem logo
Rapamycin
REF : 10-M02444CAS : 53123-88-9 		98%24,00 €~408,00 €jeu 10 Avr 25
USP logo
Sirolimus
REF : 45-1612765CAS : 53123-88-9 		- - -471,00 €mar 15 Avr 25
Targetmol logo
Rapamycin
REF : TM-T1537CAS : 53123-88-9 		97.08% - 99.03%35,00 €~283,00 €lun 14 Avr 25
Indagoo logo
(9S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-{(2R)-1-[(3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
REF : IN-DA0035KCCAS : 53123-88-9 		98%À demanderlun 14 Avr 25
Apollo Scientific logo
Rapamycin
REF : 54-BUP17166CAS : 53123-88-9 		99.02%103,00 €~930,00 €mar 15 Avr 25
TLC logo
Rapamycin (Sirolimus)
REF : 4Z-R-182CAS : 53123-88-9 		- - -À demandermar 15 Avr 25
Glentham logo
Rapamycin
REF : 7W-GA7417CAS : 53123-88-9 		98.0 - 102.0 % (anhydrous basis)33,00 €~243,00 €mar 15 Avr 25
Apollo Scientific logo
Rapamycin from Streptomyces hygroscopicus
REF : 54-BIR8101CAS : 53123-88-9 		By hplc: 99.14% (Typical Value in Batch COA)113,00 €~712,00 €mar 15 Avr 25
Biopurify logo
Rapamycin
REF : BP-BP1196CAS : 53123-88-9 		95%~99%À demanderjeu 17 Avr 25
Doctor Ehrenstorfer logo
Sirolimus
REF : 04-CA16970700CAS : 53123-88-9 		- - -484,00 €jeu 17 Avr 25
TRC logo
Rapamycin-13C,d3 (contains d0) Technical Grade
REF : TR-R124003CAS : 53123-88-9 		- - -695,00 €~4.992,00 €jeu 24 Avr 25
TRC logo
Rapamycin (>85%)
REF : TR-R124000CAS : 53123-88-9 		>85%126,00 €~840,00 €jeu 24 Avr 25
Biosynth logo
Rapamycin
REF : 3D-AE27685CAS : 53123-88-9 		Min. 95 Area-%À demanderven 25 Avr 25
Biosynth logo
Rapamycin - Bio-X ™
REF : 3D-BR164324CAS : 53123-88-9 		Min. 95%147,00 €ven 25 Avr 25
Biosynth logo
Rapamycin-13C,d3 (contains d0) - Technical Grade
REF : 3D-BR177694CAS : 53123-88-9 		Min. 95%1.127,00 €~3.838,00 €lun 19 Mai 25
discount label
Rapamycin
TCI logo
+ d'infos

Rapamycin

CAS :53123-88-9
Formule :
C51H79NO13
Degré de pureté :
>98.0%(HPLC)
Couleur et forme :
White to Almost white powder to crystal
Masse moléculaire :
914.19

Ref: 3B-R0097

25mg83,00 €
Livraison estimée en/au États-Unis, le lundi 7 avril 2025
+ d'infos
discount label
Rapamycin, 98+%
Alfa Aesar By Thermo Fisher Scientific logo
+ d'infos

Rapamycin, 98+%

CAS :53123-88-9
Blocks cytokine-mediated signal transduction pathwaysRapamycin is used to inhibit tumor growth by halting tumor cell …
Formule :
C51H79NO13
Degré de pureté :
98+%
Couleur et forme :
White to cream to yellow, Powder or crystals or crystalline powder
Masse moléculaire :
914.19

Ref: 02-J62473

50mg179,00 €
100mg231,00 €
200mg288,00 €
Livraison estimée en/au États-Unis, le mardi 8 avril 2025
+ d'infos
discount label
Rapamycin
Fluorochem logo
+ d'infos

Rapamycin

CAS :53123-88-9
M02444 - Rapamycin
Formule :
C51H79NO13
Degré de pureté :
98%
Couleur et forme :
Solid, Crystalline Powder or Granules or Powder
Masse moléculaire :
914.187

Ref: 10-M02444

1g102,00 €
5g408,00 €
10mg24,00 €
50mg31,00 €
100mg34,00 €
250mg96,00 €
500mg91,00 €
Livraison estimée en/au États-Unis, le jeudi 10 avril 2025
+ d'infos
discount label
Aucune image disponible
USP logo
+ d'infos

Sirolimus

CAS :53123-88-9
Antibiotics nesoi
Formule :
C51H79NO13
Couleur et forme :
Off-White White Powder
Masse moléculaire :
913.55514

Ref: 45-1612765

50mg471,00 €
Livraison estimée en/au États-Unis, le mardi 15 avril 2025
+ d'infos
discount label
Rapamycin
Targetmol logo
+ d'infos

Rapamycin

CAS :53123-88-9
Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with …
Formule :
C51H79NO13
Degré de pureté :
97.08% - 99.03%
Couleur et forme :
Yellow Solid
Masse moléculaire :
914.17

Ref: TM-T1537

1g283,00 €
10mg35,00 €
25mg48,00 €
50mg52,00 €
100mg69,00 €
200mg106,00 €
500mg188,00 €
1mL*10mM (DMSO)50,00 €
Livraison estimée en/au États-Unis, le lundi 14 avril 2025
+ d'infos
discount label
(9S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-{(2R)-1-[(3R,4R)-4-hydroxy-…
Indagoo logo
+ d'infos

(9S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-{(2R)-1-[(3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

CAS :53123-88-9
Formule :
C51H79NO13
Degré de pureté :
98%
Couleur et forme :
Solid
Masse moléculaire :
914.1719

Ref: IN-DA0035KC

1g120,00 €
5g305,00 €
10g549,00 €
25gÀ demander
10mg31,00 €
100mg43,00 €
250mg50,00 €
500mg74,00 €
Livraison estimée en/au États-Unis, le lundi 14 avril 2025
+ d'infos
discount label
Rapamycin
Apollo Scientific logo
+ d'infos

Rapamycin

CAS :53123-88-9
Degré de pureté :
99.02%
Masse moléculaire :
914.17g/mol

Ref: 54-BUP17166

1g429,00 €
5g930,00 €
100mg103,00 €
200mg174,00 €
500mg291,00 €
Livraison estimée en/au États-Unis, le mardi 15 avril 2025
+ d'infos
discount label
Rapamycin (Sirolimus)
TLC logo
+ d'infos

Rapamycin (Sirolimus)

CAS :53123-88-9
Formule :
C51H79NO13
Couleur et forme :
White To Off-White Solid
Masse moléculaire :
914.19

Ref: 4Z-R-182

5mgÀ demander
10mgÀ demander
25mgÀ demander
50mgÀ demander
100mgÀ demander
Livraison estimée en/au États-Unis, le mardi 15 avril 2025
+ d'infos
discount label
Rapamycin
Glentham logo
+ d'infos

Rapamycin

CAS :53123-88-9
Formule :
C51H79NO13
Degré de pureté :
98.0 - 102.0 % (anhydrous basis)
Couleur et forme :
White to yellow crystalline powder
Masse moléculaire :
914.17

Ref: 7W-GA7417

5mg33,00 €
25mg79,00 €
50mg148,00 €
100mg243,00 €
Livraison estimée en/au États-Unis, le mardi 15 avril 2025
+ d'infos
discount label
Rapamycin from Streptomyces hygroscopicus
Apollo Scientific logo
+ d'infos

Rapamycin from Streptomyces hygroscopicus

CAS :53123-88-9
Formule :
C51H79NO13
Degré de pureté :
By hplc: 99.14% (Typical Value in Batch COA)
Couleur et forme :
white powder
Masse moléculaire :
914.17g/mol

Ref: 54-BIR8101

1g210,00 €
5g712,00 €
500mg128,00 €
Livraison estimée en/au États-Unis, le mardi 15 avril 2025
+ d'infos
discount label
Rapamycin
Biopurify logo
+ d'infos

Rapamycin

CAS :53123-88-9
Formule :
C51H79NO13
Degré de pureté :
95%~99%
Masse moléculaire :
914.187

Ref: BP-BP1196

Taille indéfinieÀ demander
Livraison estimée en/au États-Unis, le jeudi 17 avril 2025
+ d'infos
discount label
Sirolimus
Doctor Ehrenstorfer logo
+ d'infos

Sirolimus

CAS :53123-88-9
Couleur et forme :
Neat

Ref: 04-CA16970700

10mg484,00 €
Livraison estimée en/au États-Unis, le jeudi 17 avril 2025
+ d'infos
discount label
Rapamycin-13C,d3 (contains d0) Technical Grade
TRC logo
+ d'infos

Rapamycin-13C,d3 (contains d0) Technical Grade

Produit contrôlé
CAS :53123-88-9
Applications Labelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the …
Formule :
C50CH76D3NO13
Couleur et forme :
Neat
Masse moléculaire :
918.18

Ref: TR-R124003

1mg695,00 €
5mg2.713,00 €
10mg4.992,00 €
Livraison estimée en/au États-Unis, le jeudi 24 avril 2025
+ d'infos
discount label
Rapamycin (>85%)
TRC logo
+ d'infos

Rapamycin (>85%)

CAS :53123-88-9
Applications A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word …
Formule :
C51H79NO13
Degré de pureté :
>85%
Couleur et forme :
Neat
Masse moléculaire :
914.17

Ref: TR-R124000

5mg126,00 €
50mg492,00 €
100mg840,00 €
Livraison estimée en/au États-Unis, le jeudi 24 avril 2025
+ d'infos
discount label
Rapamycin
Biosynth logo
+ d'infos

Rapamycin

CAS :53123-88-9
Rapamycin is a macrolide antibiotic that has been studied as a potential anticancer agent. It …
Formule :
C51H79NO13
Degré de pureté :
Min. 95 Area-%
Couleur et forme :
White Powder
Masse moléculaire :
914.17 g/mol

Ref: 3D-AE27685

1g941,00 €
2g1.271,00 €
5g2.475,00 €
250mg452,00 €
500mg723,00 €
Livraison estimée en/au États-Unis, le vendredi 25 avril 2025
+ d'infos
discount label
Rapamycin - Bio-X ™
Biosynth logo
+ d'infos

Rapamycin - Bio-X ™

CAS :53123-88-9
Rapamycin is a macrolide antibiotic that has been studied as a potential anticancer agent. It …
Formule :
C51H79NO13
Degré de pureté :
Min. 95%
Couleur et forme :
Powder
Masse moléculaire :
914.17 g/mol

Ref: 3D-BR164324

10mg147,00 €
Livraison estimée en/au États-Unis, le vendredi 25 avril 2025
+ d'infos
discount label
Rapamycin-13C,d3 (contains d0) - Technical Grade
Biosynth logo
+ d'infos

Rapamycin-13C,d3 (contains d0) - Technical Grade

Produit contrôlé
CAS :53123-88-9
Binds to FK506 binding proteins (FKBPs) to form a complex that inhibits mammalian targets of …
Formule :
C50CH76D3NO13
Degré de pureté :
Min. 95%
Masse moléculaire :
918.18 g/mol

Ref: 3D-BR177694

1mg1.127,00 €
2mg1.778,00 €
5mg3.838,00 €
Livraison estimée en/au États-Unis, le lundi 19 mai 2025
+ d'infos
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