Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(166 produits)
- Bcr-Abl(118 produits)
- EGFR(582 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2382 produits trouvés pour "Angiogenèse"
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Theliatinib tartrate
CAS :Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.Formule :C29H32N6O8Couleur et forme :SolidMasse moléculaire :592.6MCB-613
CAS :MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formule :C20H20N2ODegré de pureté :98.17% - 99.754%Couleur et forme :SolidMasse moléculaire :304.39Ref: TM-T6886
1mg43,00€2mg56,00€5mg93,00€10mg137,00€25mg245,00€50mg358,00€100mg537,00€1mL*10mM (DMSO)90,00€Ilorasertib
CAS :Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54Dovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51SUN11602
CAS :SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Formule :C26H37N5O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :451.6TAK-632
CAS :TAK-632 is a potent pan-Raf inhibitor.Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52AG 555
CAS :AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formule :C19H18N2O3Degré de pureté :98.02% - 99.94%Couleur et forme :SolidMasse moléculaire :322.36R112
CAS :R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formule :C16H13FN4O2Degré de pureté :99.27% - 99.84%Couleur et forme :SolidMasse moléculaire :312.3Ref: TM-T3185
1mg37,00€2mg49,00€5mg79,00€10mg117,00€25mg207,00€50mg311,00€100mg462,00€500mg973,00€1mL*10mM (DMSO)87,00€Blu-782
CAS :Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formule :C31H42N6O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :562.7FGFR2-IN-3 hydrochloride
CAS :FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.Formule :C28H25ClFN7O2Couleur et forme :SolidMasse moléculaire :546.0SSR128129E
CAS :SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.Formule :C18H15N2O4·NaDegré de pureté :98.79% - ≥95%Couleur et forme :SolidMasse moléculaire :346.31AZD3759 hydrochloride
CAS :AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formule :C22H24Cl2FN5O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :496.36Ref: TM-T4249
2mg34,00€5mg46,00€10mg62,00€25mg94,00€50mg167,00€100mg265,00€200mg385,00€1mL*10mM (DMSO)49,00€LDN-212854
CAS :LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Formule :C25H22N6Degré de pureté :98% - 98.71%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T1900
1mg47,00€2mg62,00€5mg92,00€10mg172,00€25mg294,00€50mg439,00€100mg660,00€200mg945,00€1mL*10mM (DMSO)102,00€CL-387785
CAS :CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Formule :C18H13BrN4ODegré de pureté :99.56% - 99.62%Couleur et forme :SolidMasse moléculaire :381.23Filgotinib
CAS :Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formule :C21H23N5O3SDegré de pureté :98.03% - ≥95%Couleur et forme :SolidMasse moléculaire :425.5JK-P3
CAS :JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formule :C18H17N3O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :323.35Acalabrutinib
CAS :Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Formule :C26H23N7O2Degré de pureté :98.94% - 99.64%Couleur et forme :SolidMasse moléculaire :465.51Ref: TM-T3626
5mg44,00€10mg57,00€25mg78,00€50mg90,00€100mg144,00€200mg215,00€500mg355,00€1mL*10mM (DMSO)48,00€ONO-4059 analog
CAS :ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formule :C25H24N6O3Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :456.5Ref: TM-T6921
1mg43,00€2mg56,00€5mg93,00€10mg137,00€25mg264,00€50mg439,00€100mg627,00€1mL*10mM (DMSO)90,00€Masitinib
CAS :Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formule :C28H30N6OSDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :498.64PP121
CAS :PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formule :C17H17N7Degré de pureté :98.45% - 99.93%Couleur et forme :SolidMasse moléculaire :319.36SU 5402
CAS :SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formule :C17H16N2O3Degré de pureté :98.91% - 99.64%Couleur et forme :Yellow-Green SolidMasse moléculaire :296.32MTX-211
CAS :MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formule :C20H14Cl2FN5O2SDegré de pureté :97.6% - >99.99%Couleur et forme :SolidMasse moléculaire :478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)170,00€NVP-TAE 226
CAS :NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.Formule :C23H25ClN6O3Degré de pureté :98.07% - 98.78%Couleur et forme :SolidMasse moléculaire :468.94Ref: TM-T1918
1mg46,00€2mg59,00€5mg96,00€10mg155,00€25mg250,00€50mg358,00€100mg537,00€1mL*10mM (DMSO)96,00€ZM323881
CAS :ZM323881 is a potent and selective inhibitor of VEGFR2 with an IC 50 of less than 2 nM.Formule :C22H18FN3O2Couleur et forme :SolidMasse moléculaire :375.4Gusacitinib HCl
CAS :Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.Formule :C24H29ClN8O2Couleur et forme :SolidMasse moléculaire :497Derazantinib
CAS :Derazantinib (ARQ-087) is a potent, ATP-competitive, orally active tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C29H29FN4ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :468.57Ref: TM-TQ0228
1mg50,00€5mg110,00€10mg160,00€25mg258,00€50mg380,00€100mg567,00€200mg805,00€1mL*10mM (DMSO)118,00€VX-11e
CAS :VX-11e (TCS ERK 11e) is a potent, selective, and orally bioavailable ERK(Extracellular Signal-Regulated Kinase) inhibitor; antitumor agent.Formule :C24H20Cl2FN5O2Degré de pureté :98.92% - ≥98%Couleur et forme :SolidMasse moléculaire :500.35EAI045
CAS :EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formule :C19H14FN3O3SDegré de pureté :98.00% - 99.12%Couleur et forme :SolidMasse moléculaire :383.4Tyrphostin AG30
CAS :Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Formule :C10H7NO4Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :205.17SU5408
CAS :SU5408 (VEGFR2 Kinase Inhibitor I) is a potent, cell-permeable inhibitor of the VEGFR2 kinase.Formule :C18H18N2O3Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :310.35Ref: TM-T4026
1mg66,00€5mg177,00€10mg268,00€25mg492,00€50mg663,00€100mg858,00€500mg1.693,00€1mL*10mM (DMSO)195,00€CP-673451
CAS :CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormule :C24H27N5O2Degré de pureté :99.62% - 99.88%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T6091
1mg49,00€2mg63,00€5mg90,00€10mg170,00€25mg334,00€50mg512,00€100mg737,00€500mg1.521,00€1mL*10mM (DMSO)108,00€Ibrutinib deacryloylpiperidine
CAS :Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Formule :C17H13N5ODegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :303.32AZD4547
CAS :AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.Formule :C26H33N5O3Degré de pureté :99.37% - 99.88%Couleur et forme :SolidMasse moléculaire :463.57Ref: TM-T1948
2mg37,00€5mg50,00€10mg59,00€25mg84,00€50mg107,00€100mg147,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)52,00€lavendustin C
CAS :lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26Ref: TM-T4185
1mg42,00€2mg55,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€1mL*10mM (DMSO)90,00€Oritinib mesylate
CAS :Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.Formule :C32H41N7O5SCouleur et forme :SolidMasse moléculaire :635.78Lapatinib tosylate
CAS :Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).Formule :C36H34ClFN4O7S2Couleur et forme :SolidMasse moléculaire :753.26AMG-47a
CAS :AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56Vorolanib
CAS :Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Formule :C23H26FN5O3Degré de pureté :97.35%Couleur et forme :SolidMasse moléculaire :439.48Ref: TM-T8491
1mg101,00€2mg142,00€5mg215,00€10mg340,00€25mg583,00€50mg842,00€100mg1.144,00€200mg1.521,00€1mL*10mM (DMSO)236,00€ODM-203
CAS :ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormule :C26H21F2N5O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :505.54TAS6417
CAS :Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€1mL*10mM (DMSO)203,00€Saracatinib
CAS :Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03AZD-3463
CAS :AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95DGY-06-116
CAS :DGY-06-116 is an selective and irreversible covalent inhibitor of Src and FGFR1 with IC50 value of 3nM and 8340 nM, respectively.Formule :C32H33ClN8O2Degré de pureté :97.65%Couleur et forme :SolidMasse moléculaire :597.11Ref: TM-T22306
2mg39,00€5mg60,00€10mg92,00€25mg173,00€50mg269,00€100mg404,00€200mg570,00€1mL*10mM (DMSO)66,00€PP2
CAS :PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formule :C15H16ClN5Degré de pureté :98% - 98.21%Couleur et forme :White SolidMasse moléculaire :301.77Ref: TM-T6266
2mg44,00€5mg65,00€10mg110,00€25mg178,00€50mg304,00€100mg482,00€200mg687,00€1mL*10mM (DMSO)71,00€Larotinib mesylate hydrate
CAS :Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI), primarily targeting EGFR with an IC50 value of 0.6 nMFormule :C26H36ClFN4O11S2Couleur et forme :SolidMasse moléculaire :699.17Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56(E/Z)-Zotiraciclib
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46Ref: TM-T21503
1mg43,00€2mg56,00€5mg93,00€10mg113,00€25mg200,00€50mg330,00€100mg480,00€1mL*10mM (DMSO)90,00€Tucatinib
CAS :Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).Formule :C26H24N8O2Degré de pureté :99.05% - 99.96%Couleur et forme :SolidMasse moléculaire :480.52Ref: TM-T2364
1g1.071,00€2mg34,00€5mg50,00€10mg74,00€25mg117,00€50mg177,00€100mg333,00€500mg782,00€1mL*10mM (DMSO)82,00€Crizotinib acetate
CAS :Crizotinib is an oral c-met/HGFR tyrosine kinase inhibitor with potential cancer-fighting properties.Formule :C23H26Cl2FN5O3Couleur et forme :SolidMasse moléculaire :510.39WHI-P180 hydrochloride
CAS :WHI-P180 (Janex 3) inhibits RET, KDR and EGFR with IC50 values of 5 nM, 66 nM and 4 μM, respectively. WHI-P180 is a multi-kinase inhibitor.Formule :C16H16ClN3O3Couleur et forme :SolidMasse moléculaire :333.77Syk Inhibitor II dihydrochloride dihydrate
CAS :Potent, selective ATP-competitive Syk Inhibitor II (IC50: 41 nM), with anti-allergic properties, in dihydrochloride dihydrate form.Formule :C14H21Cl2F3N6O3Couleur et forme :SolidMasse moléculaire :449.26PD153035
CAS :PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formule :C16H14BrN3O2Degré de pureté :98.47% - 99.29%Couleur et forme :SolidMasse moléculaire :360.21NVP-AEW541
CAS :NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormule :C27H29N5ODegré de pureté :98.7% - 99.86%Couleur et forme :SolidMasse moléculaire :439.55Dovitinib
CAS :Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formule :C21H21FN6ODegré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :392.43ZM-447439
CAS :ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formule :C29H31N5O4Degré de pureté :99.11% - 99.59%Couleur et forme :Pale Yellow SolidMasse moléculaire :513.59Tyrphostin A1
CAS :Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formule :C11H8N2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :184.19KX2-361
CAS :KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFormule :C24H24FN3O2Degré de pureté :99.64% - 99.68%Couleur et forme :SolidMasse moléculaire :405.46Ref: TM-T9411
1mg77,00€5mg161,00€10mg224,00€25mg366,00€50mg515,00€100mg692,00€200mg888,00€1mL*10mM (DMSO)172,00€RG13022
CAS :RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).Formule :C16H14N2O2Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :266.29Ki20227
CAS :Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Formule :C24H24N4O5SDegré de pureté :98.97% - 99.88%Couleur et forme :SolidMasse moléculaire :480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€CGP77675 hydrate
CGP77675 hydrate: Oral Src family kinase inhibitor with IC50s of 5-20/40 nM (Src auto/phosphorylation) and has anticancer properties.Couleur et forme :SolidLazertinib
CAS :Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formule :C30H34N8O3Degré de pureté :98.7% - 99.90%Couleur et forme :SolidMasse moléculaire :554.64Ref: TM-T4485
1mg46,00€2mg59,00€5mg96,00€10mg130,00€25mg215,00€50mg309,00€100mg444,00€200mg655,00€1mL*10mM (DMSO)104,00€Foretinib
CAS :Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.Formule :C34H34F2N4O6Degré de pureté :98.07% - 99.68%Couleur et forme :SolidMasse moléculaire :632.65Ref: TM-T3113
2mg39,00€5mg57,00€10mg79,00€25mg133,00€50mg207,00€100mg354,00€500mg848,00€1mL*10mM (DMSO)79,00€TL-895
CAS :TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).Formule :C25H26FN5O2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :447.5Ref: TM-T9705
2mg39,00€5mg60,00€10mg87,00€25mg172,00€50mg266,00€100mg391,00€200mg555,00€1mL*10mM (DMSO)60,00€Ceritinib
CAS :Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.Formule :C28H36ClN5O3SDegré de pureté :98.52% - 99.77%Couleur et forme :SolidMasse moléculaire :558.14SAR131675
CAS :SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formule :C18H22N4O4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :358.39Ref: TM-T6012
1mg34,00€2mg46,00€5mg70,00€10mg105,00€25mg215,00€50mg304,00€100mg427,00€200mg587,00€1mL*10mM (DMSO)79,00€PF-562271 besylate
CAS :PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formule :C21H20F3N7O3S·C6H6O3SDegré de pureté :97.65% - 99.01%Couleur et forme :SolidMasse moléculaire :665.66Ref: TM-T6177
1mg35,00€5mg74,00€10mg94,00€25mg138,00€50mg198,00€100mg296,00€200mg427,00€1mL*10mM (DMSO)89,00€A-443654
CAS :A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).Formule :C24H23N5ODegré de pureté :98.04% - 99.51%Couleur et forme :SolidMasse moléculaire :397.47Ref: TM-T14072
1mg87,00€5mg178,00€10mg289,00€25mg537,00€50mg822,00€100mg1.234,00€200mg1.665,00€500mg2.457,00€1mL*10mM (DMSO)203,00€Almonertinib
CAS :Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Formule :C30H35N7O2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :525.64Ref: TM-T5462
1mg94,00€5mg187,00€10mg295,00€25mg497,00€50mg717,00€100mg982,00€500mg1.998,00€1mL*10mM (DMSO)235,00€FIIN-2
CAS :FIIN-2, an irreversible, pan-FGFR inhibitor, inhibits FGFR1/2/3/4 with IC50 of 3.09 nM, 4.3 nM, 27 nM and 45.3 nM, respectively.Formule :C35H38N8O4Degré de pureté :97.82% - 99.65%Couleur et forme :Crystalline SolidMasse moléculaire :634.73Afatinib oxalate
CAS :Afatinib oxalate (BIBW 2992) is an irreversible ErbB inhibitor, treating ESCC, NSCLC, and gastric cancer. Targets EGFRwt, EGFRL858R/T790M, HER2.Formule :C28H29ClFN5O11Couleur et forme :SolidMasse moléculaire :666.01FIIN-3
CAS :FIIN-3 is an irreversible inhibitor of FGFR.Formule :C34H36Cl2N8O4Degré de pureté :97.63% - 98.92%Couleur et forme :SolidMasse moléculaire :691.61ON123300
CAS :ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formule :C24H27N7ODegré de pureté :99.53% - 99.7%Couleur et forme :SolidMasse moléculaire :429.52Vatalanib succinate
CAS :Vatalanib succinate is a VEGFR, PDGFR-β, c-Kit, c-Fms, and aromatase inhibitor.Formule :C24H21ClN4O4Couleur et forme :SolidMasse moléculaire :464.91BAY 61-3606 dihydrochloride
CAS :BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formule :C20H18N6O3·2HClDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :463.32Ref: TM-T6776
1mg35,00€5mg79,00€10mg110,00€25mg177,00€50mg264,00€100mg385,00€200mg535,00€1mL*10mM (DMSO)93,00€5'-Fluoroindirubinoxime
CAS :5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).Formule :C16H10FN3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :295.27VEGFR2-IN-2
CAS :VEGFR2-IN-2 has anti-inflammatory and analgesic activities.Formule :C15H11BrN2ODegré de pureté :99.504%Couleur et forme :SolidMasse moléculaire :315.16Ref: TM-T9724
1mg35,00€5mg73,00€10mg105,00€25mg195,00€50mg311,00€100mg445,00€200mg617,00€1mL*10mM (DMSO)93,00€JI-101
CAS :JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formule :C22H20BrN5O2Degré de pureté :99.41% - 99.97%Couleur et forme :SolidMasse moléculaire :466.33Vandetanib hydrochloride
CAS :Vandetanib hydrochloride is an oral VEGFR2 inhibitor with an IC50 of 40 nM, also targeting VEGFR3 (110 nM) and EGFR (500 nM).Formule :C22H25BrClFN4O2Couleur et forme :SolidMasse moléculaire :511.81HG-14-10-04
CAS :HG-14-10-04 is a potent and specific ALK inhibitor.Formule :C29H34ClN7ODegré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :532.08Ref: TM-T4015
1mg49,00€5mg92,00€10mg152,00€25mg222,00€50mg289,00€100mg409,00€200mg590,00€1mL*10mM (DMSO)111,00€Bevacizumab
CAS :Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Degré de pureté :95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :146.53 kDaRef: TM-T9904
1mg127,00€2mg202,00€5mg376,00€10mg560,00€25mg895,00€50mg1.216,00€100mg1.634,00€200mg2.213,00€UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formule :C19H25ClN8Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :400.91Ref: TM-T2056L
1mg84,00€5mg168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€1mL*10mM (DMSO)185,00€TG101209
CAS :TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formule :C26H35N7O2SDegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :509.67Zoligratinib
CAS :Zoligratinib (CH5183284) is a selective and orally available FGFR inhibitor, which is for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.Formule :C20H16N6ODegré de pureté :95.28% - 99.51%Couleur et forme :SolidMasse moléculaire :356.38Tirbanibulin
CAS :Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53Ref: TM-T6345
1mg34,00€5mg60,00€10mg73,00€25mg142,00€50mg253,00€100mg424,00€200mg605,00€1mL*10mM (DMSO)63,00€GSK1838705A
CAS :GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formule :C27H29FN8O3Degré de pureté :98.89% - >99.99%Couleur et forme :SolidMasse moléculaire :532.57Fedratinib
CAS :Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formule :C27H36N6O3SDegré de pureté :97.31% - 99.96%Couleur et forme :SolidMasse moléculaire :524.68Ref: TM-T1995
1g592,00€5mg50,00€10mg65,00€50mg107,00€100mg127,00€200mg205,00€500mg447,00€1mL*10mM (DMSO)54,00€Neratinib
CAS :Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formule :C30H29ClN6O3Degré de pureté :96.17% - 99.85%Couleur et forme :SolidMasse moléculaire :557.04Allitinib tosylate
CAS :Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.Formule :C31H26ClFN4O5SDegré de pureté :98.46% - 98.68%Couleur et forme :SolidMasse moléculaire :621.08CA-4948
CAS :CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formule :C24H25N7O5Degré de pureté :99.35% - 99.88%Couleur et forme :SolidMasse moléculaire :491.5Ref: TM-T9027
1mg34,00€2mg49,00€5mg73,00€10mg93,00€25mg166,00€50mg295,00€100mg507,00€1mL*10mM (DMSO)79,00€(Rac)-IBT6A
CAS :(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formule :C22H22N6ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :386.45Ref: TM-T10626
1mg44,00€2mg57,00€5mg93,00€10mg120,00€25mg215,00€50mg313,00€100mg439,00€200mg628,00€1mL*10mM (DMSO)92,00€PD-089828
CAS :PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Formule :C18H18Cl2N6ODegré de pureté :97.39%Couleur et forme :SolidMasse moléculaire :405.28FLT3-IN-2
CAS :FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).Formule :C21H16ClF3N4Degré de pureté :97.57% - 98.53%Couleur et forme :SolidMasse moléculaire :416.83Ref: TM-T1938
1mg40,00€2mg52,00€5mg82,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€1mL*10mM (DMSO)93,00€EHop-016
CAS :EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formule :C25H30N6ODegré de pureté :98.99% - >99.99%Couleur et forme :SolidMasse moléculaire :430.55Ref: TM-T2427
5mg46,00€10mg70,00€25mg120,00€50mg202,00€100mg316,00€200mg467,00€500mg747,00€1mL*10mM (DMSO)49,00€Cerdulatinib
CAS :Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formule :C20H27N7O3SDegré de pureté :98.74% - 99.49%Couleur et forme :SolidMasse moléculaire :445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€1mL*10mM (DMSO)81,00€BIIB068
CAS :BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formule :C23H29N7O2Degré de pureté :97.98%Couleur et forme :SolidMasse moléculaire :435.52Ref: TM-T9192
1mg46,00€5mg90,00€10mg152,00€25mg264,00€50mg398,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)100,00€BMS-536924
CAS :BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96NVP-BHG712
CAS :NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFormule :C26H20F3N7ODegré de pureté :97.32% - 98.63%Couleur et forme :SolidMasse moléculaire :503.48Ref: TM-T6348
1mg34,00€5mg74,00€10mg105,00€25mg200,00€50mg371,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)84,00€ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47Radotinib
CAS :Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably
Formule :C27H21F3N8ODegré de pureté :99.13% - 99.97%Couleur et forme :SolidMasse moléculaire :530.5MELK-8a
CAS :MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).Formule :C25H32N6OCouleur et forme :SolidMasse moléculaire :432.56
