Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(166 produits)
- Bcr-Abl(118 produits)
- EGFR(582 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2382 produits trouvés pour "Angiogenèse"
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Ensartinib
CAS :Ensartinib (X-396) is a potent and orally active dual ALK/MET inhibitor for the treatment of ALK-positive non-small cell lung cancer (NSCLC).Formule :C26H27Cl2FN6O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :561.44M1001
CAS :M1001 is a HIF-2α agonist.Formule :C17H17N3O2SDegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :327.4Crizotinib
CAS :Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formule :C21H22Cl2FN5ODegré de pureté :99% - 99.87%Couleur et forme :SolidMasse moléculaire :450.34Ref: TM-T1661
2mgÀ demander5mg33,00€10mg49,00€25mg55,00€50mg64,00€100mg88,00€500mg147,00€1mL*10mM (DMSO)50,00€CA-4948
CAS :CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formule :C24H25N7O5Degré de pureté :99.35% - 99.88%Couleur et forme :SolidMasse moléculaire :491.5Ref: TM-T9027
1mg34,00€2mg49,00€5mg73,00€10mg93,00€25mg166,00€50mg295,00€100mg507,00€1mL*10mM (DMSO)79,00€Derazantinib dihydrochloride
CAS :Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.Formule :C29H31Cl2FN4OCouleur et forme :SolidMasse moléculaire :541.49Gandotinib
CAS :LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).Formule :C23H25ClFN7ODegré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :469.94PF-6274484
CAS :PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.Formule :C18H14ClFN4O2Degré de pureté :97.71%Couleur et forme :SolidMasse moléculaire :372.78Ref: TM-T22396
2mg38,00€5mg57,00€10mg96,00€25mg177,00€50mg333,00€100mg495,00€500mg1.071,00€1mL*10mM (DMSO)63,00€Ibrutinib
CAS :Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.Formule :C25H24N6O2Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :440.5Agerafenib
CAS :Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.Formule :C24H22F3N5O5Degré de pureté :95.78% - 99.23%Couleur et forme :SolidMasse moléculaire :517.46Ref: TM-T2070
1mg39,00€5mg93,00€10mg124,00€25mg219,00€50mg358,00€100mg530,00€200mg757,00€1mL*10mM (DMSO)90,00€Nocodazole
CAS :Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32Ref: TM-T2802
5mg34,00€10mg52,00€25mg94,00€50mg165,00€100mg268,00€200mg399,00€500mg647,00€1mL*10mM (DMSO)38,00€EHop-016
CAS :EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formule :C25H30N6ODegré de pureté :98.99% - >99.99%Couleur et forme :SolidMasse moléculaire :430.55Ref: TM-T2427
5mg46,00€10mg70,00€25mg120,00€50mg202,00€100mg316,00€200mg467,00€500mg747,00€1mL*10mM (DMSO)49,00€4-(6,7-dimethoxyquinolin-4-yl)oxyaniline
CAS :4-(6,7-dimethoxyquinolin-4-yl)oxyaniline is a quinoline used in creating drugs and pesticides.Formule :C17H16N2O3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :296.32Ritlecitinib
CAS :Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Formule :C15H19N5ODegré de pureté :98.82% - 99.92%Couleur et forme :SolidMasse moléculaire :285.34Ref: TM-T5382
2mg37,00€5mg52,00€10mg90,00€25mg205,00€50mg290,00€100mg408,00€200mg595,00€1mL*10mM (DMSO)73,00€AZD8931 diFuMaric acid
CAS :AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).Formule :C31H33ClFN5O11Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :706.1Ref: TM-T8751
1mg58,00€5mg118,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)170,00€CYC-116
CAS :CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormule :C18H20N6OSDegré de pureté :97.36% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46Tofacitinib
CAS :Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.Formule :C16H20N6ODegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :312.37AEE788
CAS :AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Formule :C27H32N6Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :440.58Ref: TM-T2116
2mg47,00€5mg70,00€10mg103,00€25mg188,00€50mg325,00€100mg490,00€500mg1.103,00€1mL*10mM (DMSO)77,00€MELK-8a
CAS :MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).Formule :C25H32N6OCouleur et forme :SolidMasse moléculaire :432.56WZ4002
CAS :WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.Formule :C25H27ClN6O3Degré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :494.97Ref: TM-T6238
2mg34,00€5mg49,00€10mg70,00€25mg111,00€50mg177,00€100mg313,00€200mg464,00€1mL*10mM (DMSO)50,00€(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.Formule :C29H32N4O8Couleur et forme :SolidMasse moléculaire :564.59Brigatinib
CAS :Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
Formule :C29H39ClN7O2PDegré de pureté :97.18% - >99.99%Couleur et forme :SolidMasse moléculaire :584.09Trastuzumab
CAS :Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.Degré de pureté :97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Couleur et forme :LiquidMasse moléculaire :145.36 kDaOlafertinib
CAS :Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.Formule :C29H28F2N6O2Degré de pureté :98.62% - 99.706%Couleur et forme :SolidMasse moléculaire :530.57WH-4-023
CAS :WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.Formule :C32H36N6O4Degré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :568.67Osimertinib
CAS :Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Formule :C28H33N7O2Degré de pureté :99.32% - >99.99%Couleur et forme :SolidMasse moléculaire :499.61Ref: TM-T2490
1g138,00€2g197,00€5g329,00€2mg34,00€5mg52,00€10mg55,00€25mg67,00€50mg80,00€100mg94,00€500mg114,00€1mL*10mM (DMSO)52,00€eCF506
CAS :eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Formule :C26H38N8O3Degré de pureté :97.85% - 98.16%Couleur et forme :SolidMasse moléculaire :510.63XL019
CAS :XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formule :C25H28N6O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :444.53Ref: TM-T3072
2mg43,00€5mg63,00€10mg92,00€25mg150,00€50mg215,00€100mg321,00€200mg477,00€1mL*10mM (DMSO)78,00€Silymarin
CAS :Silymarin, a liver-aiding polyphenolic flavonoid, is extracted from milk thistle seeds.Formule :C25H22O10Degré de pureté :98%Couleur et forme :Yellow And Brown PowderMasse moléculaire :482.441AD80
CAS :AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Formule :C22H19F4N7ODegré de pureté :99.49% - 99.75%Couleur et forme :SolidMasse moléculaire :473.43Ref: TM-T4301
1mg44,00€5mg96,00€10mg138,00€25mg268,00€50mg439,00€100mg645,00€500mg1.333,00€1mL*10mM (DMSO)90,00€4SC-203
CAS :4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formule :C33H38N8O4SDegré de pureté :99.52% - 99.84%Couleur et forme :SolidMasse moléculaire :642.77(S)-Afatinib
CAS :(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.Formule :C24H25ClFN5O3Degré de pureté :99.22% - >99.99%Couleur et forme :Off-White SolidMasse moléculaire :485.94CP-380736
CAS :CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formule :C14H18N2O5Degré de pureté :99.68%Couleur et forme :White To Off-White SolidMasse moléculaire :294.3NSC 228155
CAS :NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formule :C11H6N4O4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :290.25Ref: TM-T6908
2mg34,00€5mg48,00€10mg63,00€25mg117,00€50mg178,00€100mg334,00€200mg469,00€1mL*10mM (DMSO)50,00€OSI-930
CAS :OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formule :C22H16F3N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :443.44Theliatinib
CAS :Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).Formule :C25H26N6O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :442.51GW786034B
CAS :Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formule :C21H23N7O2S·HClDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :473.98Lorlatinib
CAS :Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogeneFormule :C21H19FN6O2Degré de pureté :99.77% - 99.95%Couleur et forme :SolidMasse moléculaire :406.41Ref: TM-T3061
1mg34,00€2mg42,00€5mg60,00€10mg89,00€25mg137,00€50mg212,00€100mg374,00€1mL*10mM (DMSO)66,00€A-176120
CAS :A-176120: potent FPP analog, inhibits farnesyltransferase, anti-angiogenic, may curb H-ras NIH3T3 tumor growth.Formule :C33H29NO9Couleur et forme :SolidMasse moléculaire :583.58hVEGF-IN-1
CAS :hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.Formule :C34H43N7O2Degré de pureté :99.76% - >99.99%Couleur et forme :SolidMasse moléculaire :581.75EAI045
CAS :EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formule :C19H14FN3O3SDegré de pureté :98.00% - 99.12%Couleur et forme :SolidMasse moléculaire :383.4Ilorasertib
CAS :Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54CZC-8004
CAS :CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34KI8751
CAS :KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Formule :C24H18F3N3O4Degré de pureté :99.22% - 99.9%Couleur et forme :SolidMasse moléculaire :469.41Ref: TM-T2446
2mg34,00€5mg50,00€10mg81,00€25mg147,00€50mg279,00€100mg447,00€200mg635,00€1mL*10mM (DMSO)52,00€Sitravatinib
CAS :Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormule :C33H29F2N5O4SDegré de pureté :98.9% - 99.85%Couleur et forme :SolidMasse moléculaire :629.68Ref: TM-T4349
5mg49,00€10mg74,00€25mg130,00€50mg200,00€100mg319,00€200mg507,00€500mg800,00€1mL*10mM (DMSO)69,00€R112
CAS :R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formule :C16H13FN4O2Degré de pureté :99.27% - 99.84%Couleur et forme :SolidMasse moléculaire :312.3Ref: TM-T3185
1mg37,00€2mg49,00€5mg79,00€10mg117,00€25mg207,00€50mg311,00€100mg462,00€500mg973,00€1mL*10mM (DMSO)87,00€AC1NS4RE
CAS :It is a tyrosine kinase inhibitor.Formule :C15H13ClN2ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :272.73CL-387785
CAS :CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Formule :C18H13BrN4ODegré de pureté :99.56% - 99.62%Couleur et forme :SolidMasse moléculaire :381.235-phenylthieno[2,3-d]pyrimidin-4-amine
CAS :5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formule :C12H9N3SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :227.29Ref: TM-T50042
2mg43,00€5mg60,00€10mg90,00€25mg138,00€50mg200,00€100mg301,00€200mg432,00€1mL*10mM (DMSO)60,00€BMS-2
CAS :BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Formule :C25H16F2N4O3Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :458.42Ref: TM-T8326
1mg67,00€2mg88,00€5mg148,00€10mg230,00€25mg430,00€50mg622,00€100mg898,00€1mL*10mM (DMSO)170,00€Arnebin 1
CAS :(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.Formule :C21H22O6Degré de pureté :98.76% - 99.81%Couleur et forme :SolidMasse moléculaire :370.40Ref: TM-T4586
1mg34,00€5mg67,00€10mg96,00€25mg138,00€50mg200,00€100mg294,00€200mg437,00€1mL*10mM (DMSO)74,00€Merestinib dihydrochloride
CAS :Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.Formule :C30H24Cl2F2N6O3Couleur et forme :SolidMasse moléculaire :625.45Tyrphostin B44, (+) enantiomer
CAS :Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Formule :C18H16N2O3Degré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :308.33Ref: TM-T22450
1mg39,00€5mg82,00€10mg115,00€25mg192,00€50mg264,00€100mg380,00€200mg515,00€1mL*10mM (DMSO)90,00€URMC-099
CAS :URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formule :C27H27N5Degré de pureté :99.32% - 99.98%Couleur et forme :SolidMasse moléculaire :421.54VEGFR-2-IN-5
CAS :VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formule :C19H24N8Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :364.45Ref: TM-T2056
1mg90,00€5mg222,00€10mg333,00€25mg560,00€50mg797,00€100mg1.071,00€1mL*10mM (DMSO)224,00€Syk Inhibitor II dihydrochloride
CAS :Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formule :C14H17Cl2F3N6ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :413.22Ref: TM-T4391
1mg130,00€2mg212,00€5mg455,00€10mg647,00€25mg947,00€50mg1.264,00€100mg1.700,00€1mL*10mM (DMSO)455,00€GluR6 antagonist-1
CAS :GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.Formule :C15H11ClN2OSDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :302.78TAK-632
CAS :TAK-632 is a potent pan-Raf inhibitor.Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52Fisogatinib
CAS :Fisogatinib (BLU-554) is a highly potent, selective, and orally active FGFR4 inhibitor.Cost-effective and quality-assured.Formule :C24H24Cl2N4O4Degré de pureté :99.27% - ≥95%Couleur et forme :SolidMasse moléculaire :503.38Ref: TM-T3456
1mg50,00€5mg114,00€10mg167,00€25mg294,00€50mg444,00€100mg670,00€500mg1.341,00€1mL*10mM (DMSO)127,00€ONO-4059 analog
CAS :ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formule :C25H24N6O3Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :456.5Ref: TM-T6921
1mg43,00€2mg56,00€5mg93,00€10mg137,00€25mg264,00€50mg439,00€100mg627,00€1mL*10mM (DMSO)90,00€Acalabrutinib
CAS :Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Formule :C26H23N7O2Degré de pureté :98.94% - 99.64%Couleur et forme :SolidMasse moléculaire :465.51Ref: TM-T3626
5mg44,00€10mg57,00€25mg78,00€50mg90,00€100mg144,00€200mg215,00€500mg355,00€1mL*10mM (DMSO)48,00€PP121
CAS :PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formule :C17H17N7Degré de pureté :98.45% - 99.93%Couleur et forme :SolidMasse moléculaire :319.361-Naphthyl PP1
CAS :1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Formule :C19H19N5Degré de pureté :99.85%Couleur et forme :White Cyrstalline SolidMasse moléculaire :317.39Masitinib
CAS :Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formule :C28H30N6OSDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :498.64LDN-212854
CAS :LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Formule :C25H22N6Degré de pureté :98% - 98.71%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T1900
1mg47,00€2mg62,00€5mg92,00€10mg172,00€25mg294,00€50mg439,00€100mg660,00€200mg945,00€1mL*10mM (DMSO)102,00€Gefitinib dihydrochloride
CAS :Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.Formule :C22H26Cl3FN4O3Couleur et forme :SolidMasse moléculaire :519.82MTX-211
CAS :MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formule :C20H14Cl2FN5O2SDegré de pureté :97.6% - >99.99%Couleur et forme :SolidMasse moléculaire :478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)170,00€Tivozanib
CAS :Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formule :C22H19ClN4O5Degré de pureté :98.08% - 99.67%Couleur et forme :SolidMasse moléculaire :454.86Ref: TM-T2456
2mg38,00€5mg57,00€10mg79,00€25mg135,00€50mg226,00€100mg405,00€200mg597,00€1mL*10mM (DMSO)63,00€SUN11602
CAS :SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Formule :C26H37N5O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :451.6TAS6417
CAS :Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€1mL*10mM (DMSO)203,00€(E/Z)-Zotiraciclib
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46Ref: TM-T21503
1mg43,00€2mg56,00€5mg93,00€10mg113,00€25mg200,00€50mg330,00€100mg480,00€1mL*10mM (DMSO)90,00€SU 5402
CAS :SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formule :C17H16N2O3Degré de pureté :98.91% - 99.64%Couleur et forme :Yellow-Green SolidMasse moléculaire :296.32Quizartinib HCl
CAS :Quizartinib (AC220/AC010220) is an oral FLT3/STK1 inhibitor for treating AML, blocking kinase-driven cell proliferation and promoting apoptosis.Formule :C29H34Cl2N6O4SCouleur et forme :SolidMasse moléculaire :633.59Adaphostin
CAS :Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Formule :C24H27NO4Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :393.487BIO
CAS :7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formule :C16H10BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :356.17GSK1838705A
CAS :GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formule :C27H29FN8O3Degré de pureté :98.89% - >99.99%Couleur et forme :SolidMasse moléculaire :532.571-Naphthyl PP1 hydrochloride
CAS :1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormule :C19H20ClN5Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :353.85Momelotinib HCl
CAS :Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formule :C23H24Cl2N6O2Couleur et forme :SolidMasse moléculaire :487.38(E)-AG 99
CAS :(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).Formule :C10H8N2O3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :204.185'-Fluoroindirubinoxime
CAS :5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).Formule :C16H10FN3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :295.27Olverembatinib dimesylate
CAS :Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Formule :C29H27F3N6O·2CH4O3SDegré de pureté :97.66% - >99.99%Couleur et forme :SolidMasse moléculaire :724.77Ref: TM-T2429
1mg37,00€5mg79,00€10mg113,00€25mg216,00€50mg289,00€100mg378,00€200mg552,00€1mL*10mM (DMSO)114,00€lavendustin C
CAS :lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26Ref: TM-T4185
1mg42,00€2mg55,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€1mL*10mM (DMSO)90,00€Dovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51Ruxolitinib phosphate
CAS :Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formule :C17H21N6O4PDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :404.36Ref: TM-T3043
1g583,00€5mg49,00€10mg62,00€25mg78,00€50mg92,00€100mg138,00€200mg215,00€500mg395,00€1mL*10mM (DMSO)56,00€Saracatinib
CAS :Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03AZD-3463
CAS :AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95SB-431542
CAS :SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.Formule :C22H16N4O3Degré de pureté :99.035% - >99.99%Couleur et forme :SolidMasse moléculaire :384.39GDC-0214
CAS :GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formule :C28H28ClF2N9O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :612.03Ref: TM-T9826
1mg93,00€5mg182,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)245,00€Tyrphostin A1
CAS :Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formule :C11H8N2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :184.19ODM-203
CAS :ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormule :C26H21F2N5O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :505.54PD-161570
CAS :PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formule :C26H35Cl2N7ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :532.51Ref: TM-T23127
1mg34,00€5mg96,00€10mg141,00€25mg289,00€50mg465,00€100mg662,00€200mg888,00€1mL*10mM (DMSO)118,00€Tranilast
CAS :Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment ofFormule :C18H17NO5Degré de pureté :99.67% - >99.99%Couleur et forme :White With Light Yellow Crystalline PowderMasse moléculaire :327.33Ref: TM-T2690
5mg43,00€10mg55,00€25mg66,00€50mg93,00€100mg119,00€200mg175,00€500mg298,00€1mL*10mM (DMSO)55,00€Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56NVP-BSK805 trihydrochloride
CAS :NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.Formule :C27H31Cl3F2N6OCouleur et forme :SolidMasse moléculaire :599.93Zorifertinib
CAS :Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formule :C22H23ClFN5O3Degré de pureté :98.20% - 99.36%Couleur et forme :White To Off-White SolidMasse moléculaire :459.9Tyrphostin AG1296
CAS :Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formule :C16H14N2O2Degré de pureté :99.94% - >99.99%Couleur et forme :SolidMasse moléculaire :266.29Ref: TM-T6711
2mg40,00€5mg58,00€10mg90,00€25mg180,00€50mg279,00€100mg411,00€200mg585,00€1mL*10mM (DMSO)81,00€PP2
CAS :PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formule :C15H16ClN5Degré de pureté :98% - 98.21%Couleur et forme :White SolidMasse moléculaire :301.77Ref: TM-T6266
2mg44,00€5mg65,00€10mg110,00€25mg178,00€50mg304,00€100mg482,00€200mg687,00€1mL*10mM (DMSO)71,00€SKLB4771
CAS :SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Formule :C25H27N7O3S2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :537.66Ref: TM-T2051
1mg63,00€2mg93,00€5mg124,00€10mg177,00€25mg371,00€50mg557,00€100mg792,00€500mg1.611,00€1mL*10mM (DMSO)148,00€WS6
CAS :WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Formule :C29H31F3N6O3Degré de pureté :97.65% - 99.95%Couleur et forme :SolidMasse moléculaire :568.59NVP-AEW541
CAS :NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormule :C27H29N5ODegré de pureté :98.7% - 99.86%Couleur et forme :SolidMasse moléculaire :439.55(Z)-SU4312
CAS :(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
Formule :C17H16N2ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :264.32
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