Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(167 produits)
- Bcr-Abl(118 produits)
- EGFR(581 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2382 produits trouvés pour "Angiogenèse"
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Dovitinib lactate
CAS :Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formule :C24H27FN6O4Degré de pureté :99.54% - 99.77%Couleur et forme :SolidMasse moléculaire :482.51Ref: TM-T7104
5mg49,00€10mg74,00€25mg122,00€50mg202,00€100mg339,00€200mg507,00€500mg800,00€1mL*10mM (DMSO)54,00€Alflutinib mesylate
CAS :Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.Formule :C29H35F3N8O5SDegré de pureté :97.94% - 99.63%Couleur et forme :SolidMasse moléculaire :664.70ATH686
CAS :ATH686 is an potent and selective Inhibitor of FLT3.Formule :C25H28F3N7O2Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :515.53Ref: TM-T7673
1mg106,00€5mg259,00€10mg416,00€25mg707,00€50mg938,00€100mg1.293,00€1mL*10mM (DMSO)283,00€Ceritinib dihydrochloride
CAS :Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase with antitumour effect.Formule :C28H38Cl3N5O3SDegré de pureté :99.85% - 99.99%Couleur et forme :SolidMasse moléculaire :631.062,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS :2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.Formule :C16H13Cl2N3O2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :350.2Tandutinib
CAS :Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formule :C31H42N6O4Degré de pureté :99.45% - ≥98%Couleur et forme :White SolidMasse moléculaire :562.7Dovitinib
CAS :Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Formule :C21H21FN6ODegré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :392.43Xanthinol Nicotinate
CAS :Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increasedFormule :C13H21N5O4·C6H5NO2Degré de pureté :99.91%Couleur et forme :White Crystalline PowderMasse moléculaire :434.45Futibatinib
CAS :Futibatinib (TAS-120) is an orally active, potent,and irreversible FGFR inhibitor of FGFR1, FGFR2, FGFR3, and FGFR4.Cost-effective and quality-assured.Formule :C22H22N6O3Degré de pureté :97.66% - 99.44%Couleur et forme :SolidMasse moléculaire :418.45Ref: TM-T5044
1mg50,00€5mg114,00€10mg167,00€25mg313,00€50mg485,00€100mg627,00€200mg890,00€1mL*10mM (DMSO)127,00€(Z)-SU4312
CAS :(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
Formule :C17H16N2ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :264.32Desmethylanethol trithione
CAS :Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.
Formule :C9H6OS3Degré de pureté :98.05% - 98.41%Couleur et forme :SolidMasse moléculaire :226.34WP1066
CAS :WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22JI-101
CAS :JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formule :C22H20BrN5O2Degré de pureté :99.41% - 99.97%Couleur et forme :SolidMasse moléculaire :466.33Tyrphostin A9
CAS :Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFormule :C18H22N2ODegré de pureté :98.21% - 99.87%Couleur et forme :Yellow SolidMasse moléculaire :282.38Momelotinib HCl
CAS :Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formule :C23H24Cl2N6O2Couleur et forme :SolidMasse moléculaire :487.38Gusacitinib HCl
CAS :Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.Formule :C24H29ClN8O2Couleur et forme :SolidMasse moléculaire :497BI-4020
CAS :BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.Formule :C30H38N8O2Degré de pureté :97.21% - >99.99%Couleur et forme :SolidMasse moléculaire :542.68Ref: TM-T10534
1mg161,00€5mg376,00€10mg538,00€25mg803,00€50mg1.071,00€100mg1.431,00€200mg1.953,00€1mL*10mM (DMSO)447,00€Alectinib
CAS :Alectinib (RG-7853) is an ALK inhibitor that is selective, orally active, and ATP-competitive. Alectinib has antitumor activity. Cost-effective and quality-assured.Formule :C30H34N4O2Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :482.62Ref: TM-T1936
2mg44,00€5mg65,00€10mg82,00€50mg100,00€100mg159,00€200mg245,00€500mg414,00€1mL*10mM (DMSO)70,00€D4476
CAS :D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formule :C23H18N4O3Degré de pureté :99.7% - 99.96%Couleur et forme :SolidMasse moléculaire :398.41BMS-911543
CAS :BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formule :C23H28N8ODegré de pureté :97.69% - 99.98%Couleur et forme :SolidMasse moléculaire :432.52Filgotinib
CAS :Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formule :C21H23N5O3SDegré de pureté :98.03% - ≥95%Couleur et forme :SolidMasse moléculaire :425.5Blu-782
CAS :Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formule :C31H42N6O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :562.7ZD-4190
CAS :ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.Formule :C19H16BrFN6O2Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :459.27Ref: TM-T5475
1mg80,00€5mg173,00€10mg261,00€25mg414,00€50mg567,00€100mg767,00€200mg1.018,00€1mL*10mM (DMSO)175,00€ALK kinase inhibitor-1
CAS :SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.Formule :C28H32FN5O3SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :537.651-Naphthyl PP1 hydrochloride
CAS :1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormule :C19H20ClN5Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :353.85VH-298
CAS :VH-298 blocks VHL:HIF-α interaction, stabilizes HIF-α, and triggers hypoxic response differently by inhibiting VHL post-HIF-α PHD hydroxylation.
Formule :C27H33N5O4SDegré de pureté :99.17% - >99.99%Couleur et forme :SolidMasse moléculaire :523.65CEP-28122 mesylate salt
CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.Formule :C29H39ClN6O6SCouleur et forme :SolidMasse moléculaire :635.17RK-24466
CAS :RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.Formule :C23H22N4ODegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :370.45Ref: TM-T16760
1mg66,00€5mg144,00€10mg227,00€25mg393,00€50mg588,00€100mg905,00€1mL*10mM (DMSO)159,00€Regorafenib monohydrate
CAS :Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormule :C21H17ClF4N4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :500.83Ref: TM-T1792L
5mg34,00€10mg46,00€25mg65,00€50mg94,00€100mg133,00€200mg197,00€500mg329,00€1mL*10mM (DMSO)55,00€Benidipine hydrochloride
CAS :Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formule :C28H32ClN3O6Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :542.03LW6
CAS :LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formule :C26H29NO5Degré de pureté :98.1% - 98.22%Couleur et forme :SolidMasse moléculaire :435.51Ref: TM-T3494
2mg44,00€5mg65,00€10mg94,00€25mg173,00€50mg281,00€100mg424,00€500mg888,00€1mL*10mM (DMSO)65,00€Neratinib
CAS :Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formule :C30H29ClN6O3Degré de pureté :96.17% - 99.85%Couleur et forme :SolidMasse moléculaire :557.04Lenvatinib mesylate
CAS :Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formule :C22H23ClN4O7SDegré de pureté :99.03% - 99.79%Couleur et forme :SolidMasse moléculaire :522.96Fostamatinib
CAS :Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Formule :C23H26FN6O9PDegré de pureté :93.08% - 99.38%Couleur et forme :SolidMasse moléculaire :580.46Ref: TM-T6115
1mg40,00€2mg54,00€5mg84,00€10mg112,00€25mg198,00€50mg318,00€100mg520,00€500mg1.134,00€1mL*10mM (DMSO)96,00€SPHINX31
CAS :SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formule :C27H24F3N5O2Degré de pureté :99.3% - 99.87%Couleur et forme :SolidMasse moléculaire :507.51Ref: TM-T5194
1mg40,00€5mg84,00€10mg97,00€25mg180,00€50mg269,00€100mg430,00€500mg998,00€1mL*10mM (DMSO)87,00€RG14620
CAS :RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.Formule :C14H8Cl2N2Degré de pureté :99.82% - 99.87%Couleur et forme :SolidMasse moléculaire :275.13Vactosertib
CAS :Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formule :C22H18FN7Degré de pureté :98.85% - 99.81%Couleur et forme :SolidMasse moléculaire :399.42Cabozantinib
CAS :Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Formule :C28H24FN3O5Degré de pureté :99.68% - 99.88%Couleur et forme :SolidMasse moléculaire :501.51Ritlecitinib tosylate
CAS :Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.Formule :C22H27N5O4SCouleur et forme :SolidMasse moléculaire :457.549Regorafenib mesylate
CAS :Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.Formule :C22H19ClF4N4O6SCouleur et forme :SolidMasse moléculaire :578.92Danusertib
CAS :Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formule :C26H30N6O3Degré de pureté :97.88% - 98.79%Couleur et forme :White PowderMasse moléculaire :474.55PD158780
CAS :PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Formule :C14H12BrN5Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :330.18Ref: TM-T5410
1mg38,00€5mg80,00€10mg113,00€25mg205,00€50mg358,00€100mg523,00€200mg750,00€1mL*10mM (DMSO)93,00€Takeda-6d
CAS :Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formule :C27H19ClFN5O3SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :547.99Ref: TM-T22436
1mg92,00€2mg128,00€5mg178,00€10mg268,00€25mg439,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)243,00€Midostaurin
CAS :PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formule :C35H30N4O4Degré de pureté :97.61% - >99.99%Couleur et forme :SolidMasse moléculaire :570.64Ref: TM-T3211
1mg49,00€5mg84,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€1mL*10mM (DMSO)90,00€Isoliquiritin apioside
CAS :Isoliquiritin apioside, from Glycyrrhizae radix, inhibits MMP9, MAPK, NF-κB, reduces cancer cell invasion, angiogenesis, and fights oxidative DNA damage.Formule :C26H30O13Degré de pureté :98.84% - 99.27%Couleur et forme :SolidMasse moléculaire :550.51Tesevatinib
CAS :Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C24H25Cl2FN4O2Degré de pureté :97.89% - 98.66%Couleur et forme :SolidMasse moléculaire :491.39KHS 101
CAS :KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.
Formule :C18H21N5SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :339.46Bisindolylmaleimide I
CAS :Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formule :C25H24N4O2Degré de pureté :97.51% - 98.75%Couleur et forme :Orange SolidMasse moléculaire :412.48IDF-11774
CAS :IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formule :C23H32N2O2Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :368.51AST5902 mesylate(2412155-74-7 free base)
CAS :AST5902 mesylate is principal metabolite of Alflutinib in vivo. AST5902 mesylate exerts antineoplastic activity.Formule :C28H33F3N8O5SDegré de pureté :97.04% - 99.46%Couleur et forme :SolidMasse moléculaire :650.67Ref: TM-T8945L
1mg128,00€5mg253,00€10mg400,00€25mg662,00€50mg888,00€100mg1.243,00€500mg2.502,00€1mL*10mM (DMSO)405,00€BIIB068
CAS :BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formule :C23H29N7O2Degré de pureté :97.98%Couleur et forme :SolidMasse moléculaire :435.52Ref: TM-T9192
1mg46,00€5mg90,00€10mg152,00€25mg264,00€50mg398,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)100,00€Avitinib
CAS :Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formule :C26H26FN7O2Degré de pureté :99.81% - >99.99%Couleur et forme :SolidMasse moléculaire :487.534SC-203
CAS :4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formule :C33H38N8O4SDegré de pureté :99.52% - 99.84%Couleur et forme :SolidMasse moléculaire :642.77Ganetespib
CAS :Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.Formule :C20H20N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :364.4Ref: TM-T2309
5mg63,00€10mg93,00€25mg126,00€50mg158,00€100mg236,00€200mg401,00€500mg665,00€1mL*10mM (DMSO)71,00€Pantoprazole sodium
CAS :Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formule :C16H14F2N3NaO4SDegré de pureté :96.92% - 99.81%Couleur et forme :White To Off-White SolidMasse moléculaire :405.35Vemurafenib
CAS :Vemurafenib (RG7204) is a B-RAF inhibitor that inhibits RAFV600E and c-RAF-1 (IC50=31/48 nM) selectively and potently.Formule :C23H18ClF2N3O3SDegré de pureté :98% - 99.65%Couleur et forme :SolidMasse moléculaire :489.92PD173955
CAS :PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFormule :C21H16Cl2N4OSDegré de pureté :98.52% - 98.99%Couleur et forme :SolidMasse moléculaire :443.35Ref: TM-T3063
2mg35,00€5mg50,00€10mg92,00€25mg166,00€50mg248,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)94,00€CNX-2006
CAS :CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.Formule :C26H27F4N7O2Degré de pureté :98.85% - 99.16%Couleur et forme :SolidMasse moléculaire :545.53Desmethyl Erlotinib
CAS :Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).Formule :C21H21N3O4Degré de pureté :97.92% - 98.62%Couleur et forme :SolidMasse moléculaire :379.41Ref: TM-T6328
1mg50,00€2mg73,00€5mg109,00€10mg178,00€25mg314,00€50mg470,00€100mg682,00€1mL*10mM (DMSO)120,00€MLN8054
CAS :MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€1mL*10mM (DMSO)88,00€ALK5-IN-10
CAS :Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.Formule :C22H18BrN7Degré de pureté :99.935%Couleur et forme :SolidMasse moléculaire :460.33Ref: TM-T9837
1mg93,00€5mg182,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)215,00€BD750
CAS :BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM inFormule :C14H13N3OSDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :271.34NVP-BAW2881
CAS :NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.Formule :C22H15F3N4O2Degré de pureté :98.19% - 99.97%Couleur et forme :SolidMasse moléculaire :424.38Ref: TM-T3641
1mg34,00€2mg48,00€5mg71,00€10mg109,00€25mg200,00€50mg324,00€100mg470,00€500mg1.054,00€1mL*10mM (DMSO)69,00€Fedratinib hydrochloride hydrate
CAS :Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formule :C27H40Cl2N6O4SDegré de pureté :98.96% - 99.87%Couleur et forme :SolidMasse moléculaire :615.61Ruxolitinib phosphate
CAS :Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formule :C17H21N6O4PDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :404.36Ref: TM-T3043
1g583,00€5mg49,00€10mg62,00€25mg78,00€50mg92,00€100mg138,00€200mg215,00€500mg395,00€1mL*10mM (DMSO)56,00€UF010
CAS :UF010 is a potent and selective HADC inhibitor with IC50 ~0.06 μM, 0.1 μM, 0.5 μM and 1.5 μM for HDACs 3, 2, 1 and 8, respectively.Formule :C11H15BrN2ODegré de pureté :98.03% - 99.68%Couleur et forme :SolidMasse moléculaire :271.15Dasatinib N-oxide
CAS :Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.
Formule :C22H26ClN7O3SDegré de pureté :98.54% - 99.94%Couleur et forme :SolidMasse moléculaire :504CAY10594
CAS :CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.Formule :C26H28N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.53M1001
CAS :M1001 is a HIF-2α agonist.Formule :C17H17N3O2SDegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :327.4Regorafenib
CAS :Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFormule :C21H15ClF4N4O3Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :482.82Ref: TM-T1792
5mg34,00€10mg49,00€25mg75,00€50mg90,00€100mg137,00€200mg175,00€500mg294,00€1mL*10mM (DMSO)54,00€HG-14-10-04
CAS :HG-14-10-04 is a potent and specific ALK inhibitor.Formule :C29H34ClN7ODegré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :532.08Ref: TM-T4015
1mg49,00€5mg92,00€10mg152,00€25mg222,00€50mg289,00€100mg409,00€200mg590,00€1mL*10mM (DMSO)111,00€CEP-37440
CAS :CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).Formule :C30H38ClN7O3Degré de pureté :98.86% - 99.98%Couleur et forme :SolidMasse moléculaire :580.12N-piperidine Ibrutinib
CAS :N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.Formule :C22H22N6ODegré de pureté :96.65%Couleur et forme :SolidMasse moléculaire :386.45Flumatinib
CAS :Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Formule :C29H29F3N8ODegré de pureté :99.39% - 99.95%Couleur et forme :SolidMasse moléculaire :562.59Ref: TM-T4320
1mg34,00€5mg63,00€10mg82,00€25mg120,00€50mg155,00€100mg259,00€200mg388,00€500mg642,00€1mL*10mM (DMSO)82,00€AG1557
CAS :AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
Formule :C16H14IN3O2Degré de pureté :98.61% - 99.23%Couleur et forme :SolidMasse moléculaire :407.21PF-562271
CAS :PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).Formule :C21H20F3N7O3SDegré de pureté :97.17% - >99.99%Couleur et forme :SolidMasse moléculaire :507.49NRC-2694 hydrochloride
CAS :NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formule :C24H27ClN4O3Couleur et forme :SolidMasse moléculaire :454.95Fisogatinib
CAS :Fisogatinib (BLU-554) is a highly potent, selective, and orally active FGFR4 inhibitor.Cost-effective and quality-assured.Formule :C24H24Cl2N4O4Degré de pureté :99.27% - ≥95%Couleur et forme :SolidMasse moléculaire :503.38Ref: TM-T3456
1mg50,00€5mg114,00€10mg167,00€25mg294,00€50mg444,00€100mg670,00€500mg1.341,00€1mL*10mM (DMSO)127,00€(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.Formule :C29H32N4O8Couleur et forme :SolidMasse moléculaire :564.59Regorafenib Hydrochloride
CAS :Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.Formule :C21H16Cl2F4N4O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :519.28AAL-993
CAS :AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.Formule :C20H16F3N3ODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :371.36Ref: TM-T21593
1mg43,00€5mg93,00€10mg138,00€25mg260,00€50mg409,00€100mg605,00€500mg1.288,00€1mL*10mM (DMSO)92,00€BO-264
CAS :BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).Formule :C18H19N5O3Degré de pureté :98.03% - 99.81%Couleur et forme :SolidMasse moléculaire :353.38(S)-Sunvozertinib
CAS :(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Formule :C29H35ClFN7O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :584.08G-749
CAS :G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.Formule :C25H25BrN6O2Degré de pureté :98.32% - 99.60%Couleur et forme :SolidMasse moléculaire :521.41Bevacizumab
CAS :Ipilimumab targets CTLA-4, an immune checkpoint inhibitor. Bevacizumab binds to VEGF-A isoforms.Degré de pureté :95.40% - CE-SDS:97.5% SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :146.53 kDaRef: TM-T9904
1mg127,00€2mg202,00€5mg376,00€10mg560,00€25mg895,00€50mg1.216,00€100mg1.634,00€200mg2.213,00€WHI-P154
CAS :WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formule :C16H14BrN3O3Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :376.2Merestinib
CAS :Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity.Formule :C30H22F2N6O3Degré de pureté :95% - 99.71%Couleur et forme :SolidMasse moléculaire :552.53Ref: TM-T3455
1mg50,00€2mg66,00€5mg100,00€10mg137,00€25mg240,00€50mg403,00€100mg573,00€500mg1.198,00€1mL*10mM (DMSO)119,00€GN44028
CAS :GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.Formule :C18H15N3O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :305.33AG 1406
CAS :AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.Formule :C16H18N2ODegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :254.33(Rac)-IBT6A
CAS :(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formule :C22H22N6ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :386.45Ref: TM-T10626
1mg44,00€2mg57,00€5mg93,00€10mg120,00€25mg215,00€50mg313,00€100mg439,00€200mg628,00€1mL*10mM (DMSO)92,00€CYC-116
CAS :CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormule :C18H20N6OSDegré de pureté :97.36% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46MCB-613
CAS :MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formule :C20H20N2ODegré de pureté :98.17% - 99.754%Couleur et forme :SolidMasse moléculaire :304.39Ref: TM-T6886
1mg43,00€2mg56,00€5mg93,00€10mg137,00€25mg245,00€50mg358,00€100mg537,00€1mL*10mM (DMSO)90,00€KX2-361
CAS :KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFormule :C24H24FN3O2Degré de pureté :99.64% - 99.68%Couleur et forme :SolidMasse moléculaire :405.46Ref: TM-T9411
1mg77,00€5mg161,00€10mg224,00€25mg366,00€50mg515,00€100mg692,00€200mg888,00€1mL*10mM (DMSO)172,00€Rigosertib
CAS :Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.Formule :C21H25NO8SDegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :451.49ASP3026
CAS :ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.Formule :C29H40N8O3SDegré de pureté :98.78% - 99.81%Couleur et forme :SolidMasse moléculaire :580.74Nintedanib
CAS :Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/Formule :C31H33N5O4Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :539.62EGFR-IN-12
CAS :EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Formule :C21H18F3N5ODegré de pureté :98.3% - 99.76%Couleur et forme :SolidMasse moléculaire :413.4Ref: TM-T5168
1mg82,00€5mg159,00€10mg259,00€25mg520,00€50mg740,00€100mg1.008,00€500mg2.015,00€1mL*10mM (DMSO)168,00€Pexidartinib
CAS :Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormule :C20H15ClF3N5Degré de pureté :98.34% - 99.45%Couleur et forme :SolidMasse moléculaire :417.81Ref: TM-T2115
5mg46,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€1mL*10mM (DMSO)49,00€BMS817378
CAS :BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).Formule :C24H18ClF2N4O7PDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :578.85ON123300
CAS :ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formule :C24H27N7ODegré de pureté :99.53% - 99.7%Couleur et forme :SolidMasse moléculaire :429.52
