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Angiogenèse

Angiogenèse

Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.

Sous-catégories appartenant à la catégorie "Angiogenèse"

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2386 produits trouvés pour "Angiogenèse"

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  • JAK3-IN-12

    CAS :
    JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.
    Formule :C19H19N5O4S
    Couleur et forme :Solid
    Masse moléculaire :413.45

    Ref: TM-T62114

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • FGFR-IN-13

    CAS :
    FGFR-IN-13 (compound III-30), an irreversible covalent inhibitor of the fibroblast growth factor receptor (FGFR), effectively modulates signaling through FGFR1 (IC 50 = 0.20 ± 0.02 nM) and FGFR4 (IC 50 = 0.40 ± 0.03 nM). It suppresses the expression of crucial proteins such as total-PARP and Bcl-2, while enhancing the expression of Cleaved-PARP and Bax in a dose-dependent manner. Notably, FGFR-IN-13 demonstrates considerable antitumor and oral activity [1].
    Formule :C23H21N5O3
    Masse moléculaire :415.44

    Ref: TM-T86425

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Zotiraciclib HCl

    CAS :
    Zotiraciclib (TG02/SB1317) is a CDK/JAK2/FLT3 inhibitor potentially treating Myc-overexpressing cancers, including glioblastoma.
    Formule :C23H26Cl2N4O
    Couleur et forme :Solid
    Masse moléculaire :445.388

    Ref: TM-T70897

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • AMG-Tie2-1

    CAS :
    AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.
    Formule :C25H20F3N5O2
    Degré de pureté :98.9%
    Couleur et forme :Solid
    Masse moléculaire :479.45

    Ref: TM-T22259

    1mg
    49,00€
    5mg
    150,00€
    10mg
    215,00€
    25mg
    353,00€
    50mg
    602,00€
    100mg
    982,00€
    200mg
    1.468,00€
  • EGFR-IN-56

    CAS :
    EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.
    Formule :C23H22N4O3S
    Couleur et forme :Solid
    Masse moléculaire :434.51

    Ref: TM-T62458

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Infigratinib phosphate

    CAS :
    Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and
    Formule :C26H34Cl2N7O7P
    Degré de pureté :99.24% - 99.6%
    Couleur et forme :Solid
    Masse moléculaire :658.47

    Ref: TM-T16364

    1mL*10mM (DMSO)
    44,00€
    5mg
    46,00€
    10mg
    58,00€
    25mg
    80,00€
    50mg
    92,00€
  • TM-233

    CAS :
    TM-233 is an inhibitor of both JAK/STAT and proteasome activities that acts by inducing cell death in myeloma cells.
    Formule :C25H20O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :384.42

    Ref: TM-T24890

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • JAK-IN-11

    CAS :
    JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.
    Formule :C23H22FN5O4S
    Degré de pureté :99.75%
    Couleur et forme :Solid
    Masse moléculaire :483.52

    Ref: TM-T12549

    1mg
    269,00€
    5mg
    538,00€
    1mL*10mM (DMSO)
    610,00€
    10mg
    874,00€
    25mg
    1.594,00€
    50mg
    2.142,00€
  • PD180970

    CAS :
    PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.
    Formule :C21H15Cl2FN4O
    Degré de pureté :98.67%
    Couleur et forme :Solid
    Masse moléculaire :429.27

    Ref: TM-T23128

    100mg
    À demander
    5mg
    55,00€
    1mL*10mM (DMSO)
    60,00€
    10mg
    92,00€
    25mg
    137,00€
    50mg
    198,00€
  • BLK-IN-2

    CAS :
    BLK-IN-2为一种高效、选择性且不可逆的B-淋巴酪氨酸激酶(BLK)抑制剂,具有5.9 nM的IC50值。该化合物亦能抑制BTK,其IC50值为202.0 nM。BLK-IN-2在多种淋巴瘤细胞中展现出显著的抗增殖作用。
    Formule :C39H41N9O3
    Couleur et forme :Solid
    Masse moléculaire :683.8

    Ref: TM-T73366

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • Depatuxizumab mafodotin

    CAS :
    Depatuxizumab mafodotin, an antibody-drug conjugate (ADC) targeting the epidermal growth factor receptor (EGFR), is utilized in cancer research [1].
    Couleur et forme :Liquid

    Ref: TM-T9901A-027

    1mg
    938,00€
    5mg
    2.544,00€
  • BCR-ABL-IN-2

    CAS :
    BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).
    Formule :C24H25Cl2N5O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :502.39

    Ref: TM-T10489

    25mg
    2.178,00€
    50mg
    2.862,00€
    100mg
    3.870,00€
  • MAX-40279 hemifumarate

    CAS :
    MAX-40279 hemifumarate inhibits FLT3 and FGFR kinases, showing promise for AML treatment.
    Formule :C48H50F2N12O6S2
    Couleur et forme :Solid
    Masse moléculaire :993.12

    Ref: TM-T63916

    25mg
    825,00€
    50mg
    1.071,00€
    100mg
    1.674,00€
  • TG 100801 Hydrochloride

    CAS :
    TG 100801: prodrug for macular degeneration. TG 100572: inhibits kinases (VEGFRs, FGFRs, PDGFRβ, Src family), with varying IC50s.
    Formule :C33H31Cl2N5O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :616.54

    Ref: TM-T13157L

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Atopaxar Hydrobromide

    CAS :
    Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.
    Formule :C29H39BrFN3O5
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :608.54

    Ref: TM-T1986L

    1mg
    231,00€
    2mg
    340,00€
    5mg
    575,00€
    10mg
    802,00€
    25mg
    1.234,00€
    50mg
    1.603,00€
  • DB07107

    CAS :
    DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM).
    Formule :C23H22N4O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :370.45

    Ref: TM-T15056

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-64

    CAS :
    EGFR-IN-64 inhibits EGFR with 0.33 μM IC50, showing promising anticancer properties.
    Formule :C20H21N3O3
    Couleur et forme :Solid
    Masse moléculaire :351.4

    Ref: TM-T61225

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • AC430

    CAS :
    AC430, a specific JAK2 inhibitor for cancer and autoimmune therapy, excels in preclinical trials with low doses. Developed by Ambit.
    Formule :C19H16FN5O
    Couleur et forme :Solid
    Masse moléculaire :349.36

    Ref: TM-T70870

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Aminoquinuride

    CAS :
    Surfen, or Aminoquinuride, reduces inflammation but blocks remyelination in MS mouse models and regulates murine T cell activation.
    Formule :C21H20N6O
    Couleur et forme :Solid
    Masse moléculaire :372.42

    Ref: TM-T69320

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • HKI-357 dimaleate

    CAS :
    HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
    Formule :C39H37ClFN5O11
    Couleur et forme :Solid
    Masse moléculaire :806.2

    Ref: TM-T68360

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • KL-1156

    CAS :
    KL-1156 is an NF-κB inhibitor. It is also a lipopolysaccharide (LPS)-induced nitric oxide production inhibitor.
    Formule :C17H17NO4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :299.32

    Ref: TM-T24262

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Rogaratinib

    CAS :
    Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR).
    Formule :C23H26N6O3S
    Degré de pureté :99.54%
    Couleur et forme :Solid
    Masse moléculaire :466.56

    Ref: TM-T16781

    1mg
    139,00€
  • FN-1501

    CAS :
    FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively).
    Formule :C22H25N9O
    Degré de pureté :97.4%
    Couleur et forme :Solid
    Masse moléculaire :431.49

    Ref: TM-T15335

    1mg
    87,00€
    5mg
    177,00€
    1mL*10mM (DMSO)
    203,00€
    10mg
    295,00€
    25mg
    537,00€
    50mg
    807,00€
    100mg
    1.099,00€
  • Spebrutinib besylate

    CAS :
    Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).
    Formule :C28H28FN5O6S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :581.62

    Ref: TM-T14357

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Sch 13835

    CAS :
    Sch 13835 is an inhibitor of platelet derived growth factor.
    Formule :C15H10ClNO4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :335.76

    Ref: TM-T28704

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR T790M/L858R-IN-5

    CAS :
    EGFR T790M/L858R-IN-5 (example 52) functions as a potent EGFR T790M/L858R inhibitor, demonstrating a 92.9% inhibition rate at a concentration of 0.05 μM [1].
    Formule :C28H31N9O
    Masse moléculaire :509.61

    Ref: TM-T86346

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EL-102

    CAS :
    EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.
    Formule :C19H16N2O3S2
    Degré de pureté :99.34%
    Couleur et forme :Solid
    Masse moléculaire :384.47

    Ref: TM-T15205

    1mg
    93,00€
    1mL*10mM (DMSO)
    173,00€
    5mg
    205,00€
    10mg
    331,00€
    25mg
    515,00€
    50mg
    700,00€
    100mg
    1.044,00€
  • FGFR2-IN-2

    CAS :
    FGFR2-IN-2 is a specific FGFR2 inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used in the study of cancer and cardiovascular disease.
    Formule :C23H22N4O
    Degré de pureté :98.09%
    Couleur et forme :Solid
    Masse moléculaire :370.45

    Ref: TM-T61473

    5mg
    À demander
    1mg
    75,00€
  • HS-438

    CAS :
    HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.
    Formule :C17H17N3O3S
    Couleur et forme :Solid
    Masse moléculaire :343.4

    Ref: TM-T27555

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • FLT3/ITD-IN-2

    CAS :
    FLT3/ITD-IN-2: Powerful FLT3/ITD, FLT3D835Y, and FLT3 inhibitor; hinders AML cell growth. IC50s: 0.3-1.0 nM.
    Formule :C23H26F3N7O2
    Couleur et forme :Solid
    Masse moléculaire :489.49

    Ref: TM-T63274

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Tarlox-TKI

    CAS :
    Tarlox-TKI (Kinase inhibitor-1) is a pan-ErbB inhibitor, the active ingredient of Tarloxotinib, which has antitumor activity.
    Formule :C19H18BrClN6O
    Degré de pureté :97.03%
    Couleur et forme :Solid
    Masse moléculaire :461.74

    Ref: TM-T11761

    1mg
    138,00€
    1mL*10mM (DMSO)
    241,00€
  • TK4b

    CAS :
    TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) & 19.40 nM (JAK2).
    Formule :C21H22N2O2
    Couleur et forme :Solid
    Masse moléculaire :334.41

    Ref: TM-T61020

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • TX-1918

    CAS :
    TX-1918, a tyrphostin, blocks eEF-2K to hinder HepG2, HCT116 cell growth.
    Formule :C14H12O3
    Couleur et forme :Solid
    Masse moléculaire :228.24

    Ref: TM-T71815

    1mg
    105,00€
    5mg
    379,00€
    10mg
    512,00€
  • Nuvenzepine

    CAS :
    Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.
    Formule :C19H20N4O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :336.39

    Ref: TM-T16362

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • JAK-IN-20

    CAS :
    JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.
    Formule :C28H30FN7O2
    Couleur et forme :Solid
    Masse moléculaire :515.58

    Ref: TM-T63581

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Peficitinib hydrochloride

    CAS :
    Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).
    Formule :C18H23ClN4O2
    Couleur et forme :Solid
    Masse moléculaire :362.86

    Ref: TM-T61365

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • pan-HER-IN-1

    CAS :
    Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.
    Formule :C19H14BrN5O
    Couleur et forme :Solid
    Masse moléculaire :408.25

    Ref: TM-T62047

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • AAE871

    CAS :
    AAE871 is a type I FLT3 inhibitor.
    Formule :C24H34N8O2S
    Couleur et forme :Solid
    Masse moléculaire :498.64

    Ref: TM-T69497

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • AG-13958 monohydrochloride

    CAS :
    AG-13958 monohydrochloride, a VEGFA inhibitor, may treat neovascular AMD to prevent rapid vision loss.
    Formule :C26H23ClFN7O
    Couleur et forme :Solid
    Masse moléculaire :503.96

    Ref: TM-T69452

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • c-ABL-IN-4

    CAS :
    c-ABL-IN-4 is a potent inhibitor of c-Abl.
    Formule :C18H11ClF3N3O3
    Couleur et forme :Solid
    Masse moléculaire :409.75

    Ref: TM-T62065

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • c-ABL-IN-3

    CAS :
    c-ABL-IN-3, from patent WO2021048567A1, is a potent c-Abl inhibitor for researching ALS, PD, and cancer.
    Formule :C17H11F3N4O3
    Couleur et forme :Solid
    Masse moléculaire :376.29

    Ref: TM-T61546

    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.375,00€
  • BTK inhibitor 10

    CAS :
    BTK inhibitor 10, an oral drug from patent WO2018145525, may treat rheumatoid arthritis.
    Formule :C25H23N5O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :441.48

    Ref: TM-T10627

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • J-1048

    CAS :
    J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-β/
    Formule :C23H17FN6S2
    Couleur et forme :Solid
    Masse moléculaire :460.55

    Ref: TM-T78790

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Flonoltinib

    CAS :
    Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.
    Formule :C25H34FN7O
    Degré de pureté :99.52%
    Couleur et forme :Solid
    Masse moléculaire :467.58

    Ref: TM-T11707

    1mg
    71,00€
    5mg
    112,00€
    1mL*10mM (DMSO)
    124,00€
    10mg
    175,00€
    25mg
    279,00€
    50mg
    460,00€
  • UNC-CA359

    CAS :
    UNC-CA359: potent EGFR inhibitor, IC50=18 nM, strong anti-tumor effect, promising for chordoma.
    Formule :C18H14ClN3O2
    Couleur et forme :Solid
    Masse moléculaire :339.78

    Ref: TM-T61077

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • NSC 33994

    CAS :
    NSC 33994 is a selective inhibitor of JAK2 (IC50 = 60 nM). It also shows no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.
    Formule :C28H42N2O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :438.65

    Ref: TM-T23091

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • JAK3/BTK-IN-6

    CAS :
    JAK3/BTK-IN-6: potent BTK (0.6 nM) & JAK3 (0.4 nM) inhibitor, stable in human liver, for blood/immune research.
    Formule :C21H17BF3N5O3
    Couleur et forme :Solid
    Masse moléculaire :455.2

    Ref: TM-T62813

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-21

    CAS :
    EGFR-IN-21, a potent EGFR inhibitor, exhibits an IC50 of 0.38 nM, demonstrating significant antitumor activity.
    Formule :C36H44BrN10O2P
    Couleur et forme :Solid
    Masse moléculaire :759.68

    Ref: TM-T73103

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • BCR-ABL-IN-6

    CAS :
    BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.
    Formule :C27H22F3N5O2
    Couleur et forme :Solid
    Masse moléculaire :505.49

    Ref: TM-T63450

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • VS 8

    CAS :
    VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.
    Formule :C26H20F3N3O3
    Couleur et forme :Solid
    Masse moléculaire :479.45

    Ref: TM-T63147

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR/HER2-IN-2

    CAS :
    EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual EGFR and HER2 inhibitor that acts on both EGFR (IC50: 5.02 μM) and HER2 (IC50: 0.83 μM).
    Formule :C26H23N5O3
    Couleur et forme :Solid
    Masse moléculaire :453.49

    Ref: TM-T62776

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • JBJ-09-063 hydrochloride


    JBJ-09-063 hydrochloride: targeted EGFR inhibitor, effective for various mutations and TKI-resistant lung cancer models.
    Formule :C31H30ClFN4O3S
    Couleur et forme :Solid
    Masse moléculaire :593.11

    Ref: TM-T72237

    25mg
    1.179,00€
    50mg
    1.539,00€
    100mg
    2.250,00€
  • EGFR-IN-25

    CAS :
    EGFR-IN-25, an efficacious EGFR inhibitor, demonstrates IC50 values of 9 nM for BaF3 cells (EGFR DEL19/T790M/C797S) and 60 nM for A431 cells (WT), respectively.
    Formule :C34H43N9O2
    Couleur et forme :Solid
    Masse moléculaire :609.76

    Ref: TM-T73101

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-54

    CAS :
    EGFR-IN-54 (Compound 3c) is a potent inhibitor of EGFR (IC50: 1.623 μM) and is toxic to cancer cells.
    Formule :C17H14N4O4S3
    Couleur et forme :Solid
    Masse moléculaire :434.51

    Ref: TM-T62457

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • NSC114792

    CAS :
    NSC114792 is a selective JAK3 inhibitor.
    Formule :C26H32N4O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :464.62

    Ref: TM-T24549

    25mg
    1.369,00€
  • EGFR-IN-52

    CAS :
    EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.
    Formule :C19H18N4O3S
    Couleur et forme :Solid
    Masse moléculaire :382.44

    Ref: TM-T61646

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • EGFR/HER2/CDK9-IN-3

    CAS :
    EGFR/HER2/CDK9-IN-3 inhibits EGFR (191.08 nM IC50), HER2 (132.65 nM), CDK9 (113.98 nM); shows anti-tumor effects.
    Formule :C24H21N3O4S2
    Couleur et forme :Solid
    Masse moléculaire :479.57

    Ref: TM-T63161

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • SUN13837

    CAS :
    SUN13837, an oral FGFR modulator, crosses the BBB and shows neuroprotective promise.
    Formule :C21H29N5O2
    Couleur et forme :Solid
    Masse moléculaire :383.49

    Ref: TM-T61666

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • TYK2-IN-11

    CAS :
    TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.
    Formule :C18H17N5O3S
    Couleur et forme :Solid
    Masse moléculaire :383.42

    Ref: TM-T61658

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR/HER2-IN-3

    CAS :
    EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual EGFR and HER2 inhibitor.
    Formule :C26H23N5O3
    Couleur et forme :Solid
    Masse moléculaire :453.49

    Ref: TM-T62777

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • FLT3-IN-18

    CAS :
    FLT3-IN-18: potent, selective FLT3 inhibitor, IC50 0.003 μM, induces apoptosis, G1 arrest, blocks FLT3/STAT5, potential in AML research.
    Formule :C26H36N8O
    Couleur et forme :Solid
    Masse moléculaire :476.62

    Ref: TM-T73142

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • (R)-Elsubrutinib

    CAS :
    (R)-Elsubrutinib ((R)-ABBV-105) is a Btk inhibitor and an isomer of Elsubrutinib, suitable for inflammation research.
    Formule :C17H19N3O2
    Degré de pureté :99.05%
    Couleur et forme :Solid
    Masse moléculaire :297.35

    Ref: TM-T72653

    1mg
    145,00€
    5mg
    250,00€
    10mg
    340,00€
    1mL*10mM (DMSO)
    462,00€
    25mg
    573,00€
    50mg
    879,00€
    100mg
    1.314,00€
  • SJF620

    CAS :
    SJF620 is a potent degrader of PROTAC BTK(DC50 : 7.9 nM).
    Formule :C41H44N8O7
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :760.84

    Ref: TM-T13887

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-69

    CAS :
    EGFR-IN-69: Potent EGFR inhibitor for NSCLC research; IC50: 4.3-25.6 nM against various EGFR mutations.
    Formule :C31H37Cl2N7O3S
    Couleur et forme :Solid
    Masse moléculaire :658.64

    Ref: TM-T73153

    25mg
    858,00€
    50mg
    1.116,00€
    100mg
    1.791,00€
  • VEGFR2 Kinase Inhibitor II

    CAS :
    VEGFR2 kinase inhibitor II: Reversible, cell-permeable, targets VEGFR2 (IC50=70nM), less effective on PDGFRβ (IC50=920nM). Blocks VEGF/PDGF-stimulated growth.
    Formule :C17H15BrN2O
    Couleur et forme :Solid
    Masse moléculaire :343.22

    Ref: TM-T37079

    500µg
    268,00€
    1mg
    515,00€
  • BLK-IN-1

    CAS :
    BLK-IN-1 selectively blocks BLK and BTK with IC50s of 18.8 and 20.5 nM, used in cancer research.
    Formule :C29H23F3N6O3
    Couleur et forme :Solid
    Masse moléculaire :560.53

    Ref: TM-T63959

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • CPL304110

    CAS :
    CPL304110: oral, selective FGFR 1-3 inhibitor; IC50 - FGFR1: 0.75nM, FGFR2: 0.5nM, FGFR3: 3.05nM.
    Formule :C25H30N6O2
    Couleur et forme :Solid
    Masse moléculaire :446.54

    Ref: TM-T62652

    25mg
    690,00€
    50mg
    897,00€
    100mg
    1.476,00€
  • EGFR-IN-31

    CAS :
    EGFR-IN-31: Potent EGFR inhibitor, targets mutations & overexpression in NSCLC; potential cancer research compound. (WO2021185298A1, 2)
    Formule :C32H36FN7O2
    Couleur et forme :Solid
    Masse moléculaire :569.67

    Ref: TM-T64030

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • FLT3/D835Y-IN-1

    CAS :
    FLT3/D835Y-IN-1, an oral FLT3 inhibitor (IC50: FLT3 - 0.26 nM, D835Y - 0.18 nM), shows anticancer potential in AML research.
    Formule :C22H21N5O3
    Couleur et forme :Solid
    Masse moléculaire :403.43

    Ref: TM-T61977

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-57

    CAS :
    EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.
    Formule :C22H15N3O2S
    Couleur et forme :Solid
    Masse moléculaire :385.44

    Ref: TM-T61696

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-60

    CAS :
    EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.
    Formule :C28H28Cl2N6O
    Couleur et forme :Solid
    Masse moléculaire :535.47

    Ref: TM-T63769

    25mg
    1.927,00€
    50mg
    2.507,00€
    100mg
    3.168,00€
  • ProMMP-9 inhibitor-3c

    CAS :
    ProMMP-9 inhibitor-3c hinders MMP-9 homodimers, blocks proMMP-9/α4β1 integrin/CD44 binding, and detaches EGFR.
    Formule :C18H20FN3O2S
    Couleur et forme :Solid
    Masse moléculaire :361.43

    Ref: TM-T69875

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • ZT55

    CAS :
    ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.
    Formule :C17H16N2O3
    Couleur et forme :Solid
    Masse moléculaire :296.32

    Ref: TM-T73567

    25mg
    642,00€
    50mg
    1.026,00€
    100mg
    1.648,00€
  • VEGFR-2-IN-24

    CAS :
    VEGFR-2-IN-24 is a potent inhibitor of VEGFR-2 (IC50: 0.22 μM) and can be used to study tumors.
    Formule :C28H23N3O6S
    Couleur et forme :Solid
    Masse moléculaire :529.56

    Ref: TM-T63722

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • FGFR4-IN-11

    CAS :
    FGFR4-IN-11: selective, covalent FGFR4 inhibitor; IC50=2.1 nM; blocks FGF19 pathway; anticancer.
    Formule :C29H29N5O5
    Couleur et forme :Solid
    Masse moléculaire :527.57

    Ref: TM-T63704

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • c-Met-IN-14

    CAS :
    c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.
    Formule :C34H38ClFN4O7S
    Couleur et forme :Solid
    Masse moléculaire :701.2

    Ref: TM-T73022

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • BI-1622

    CAS :
    BI-1622, an oral HER2 inhibitor, IC50: 7 nM, >25x selectivity over EGFR, shows effective in vivo antitumor activity.
    Formule :C26H24N10O2
    Couleur et forme :Solid
    Masse moléculaire :508.53

    Ref: TM-T63492

    25mg
    1.260,00€
    50mg
    1.639,00€
    100mg
    2.250,00€
  • EGFR-IN-26

    CAS :
    EGFR-IN-26 is an EGFR inhibitor that can be used in cancer research.
    Formule :C29H34N6O3
    Couleur et forme :Solid
    Masse moléculaire :514.62

    Ref: TM-T63571

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • TRK/ALK-IN-1


    TRK/ALK-IN-1: Potent dual TRK & ALK inhibitor; IC50s: 2.2nM (TRKA), 9.3nM (ALK WT), 38nM (ALK L1196M); cancer research potential.
    Formule :C31H35ClF2N8O2S
    Couleur et forme :Solid
    Masse moléculaire :657.18

    Ref: TM-T72931

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • FGFR3-IN-1

    CAS :
    FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor that inhibits FGFR1 (IC50: 40 nM), FGFR2 (IC50: 5.1 nM) and FGFR3 (IC50: 12 nM).
    Formule :C28H39N9O3S
    Couleur et forme :Solid
    Masse moléculaire :581.73

    Ref: TM-T64107

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • PHM16

    CAS :
    PHM16 is an ATP competitive FAK and FGFR2 inhibitor.
    Formule :C20H22N6O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :410.43

    Ref: TM-T24634

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-49

    CAS :
    EGFR-IN-49 selectively inhibits EGFR mutations T790M (IC50: 65 nM) & T790M/L858R (IC50: 13.6 nM), triggering apoptosis dose-dependently.
    Formule :C22H15N5O2S
    Couleur et forme :Solid
    Masse moléculaire :413.45

    Ref: TM-T62113

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • TIE-2/VEGFR-2 kinase-IN-1

    CAS :
    TIE-2/VEGFR-2 kinase-IN-1 synthesizes inhibitors for angiogenesis-related disease research.
    Formule :C13H11N3O2
    Couleur et forme :Solid
    Masse moléculaire :241.25

    Ref: TM-T8817

    25mg
    1.215,00€
    50mg
    1.584,00€
    100mg
    2.412,00€
  • Erbstatin

    CAS :
    Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.
    Formule :C9H9NO3
    Couleur et forme :Solid
    Masse moléculaire :179.17

    Ref: TM-T24039

    1mg
    1.108,00€
  • PD-173956

    CAS :
    PD-173956 is an inhibitor of the Src family tyrosine kinases.
    Formule :C20H13Cl2FN4O
    Couleur et forme :Solid
    Masse moléculaire :415.25

    Ref: TM-T28345

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-55

    CAS :
    "EGFR-IN-55 targets EGFRWT (70 nM IC50) & EGFRL858R/T790M (3.9 nM IC50), halts NCI-H1975 cell cycle in G0/G1, showing anticancer properties."
    Formule :C25H25Cl2N7O2
    Couleur et forme :Solid
    Masse moléculaire :526.42

    Ref: TM-T63693

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • CP-690550A

    CAS :
    Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.
    Formule :C15H21N5O2
    Couleur et forme :Solid
    Masse moléculaire :303.36

    Ref: TM-T31074

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Ficonalkib

    CAS :
    Ficonalkib is a potent antineoplastic agent that inhibits the Anaplastic Lymphoma Kinase (ALK) tyrosine kinase receptor.
    Formule :C29H39N7O3S
    Couleur et forme :Solid
    Masse moléculaire :565.73

    Ref: TM-T73189

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR/CDK2-IN-1

    CAS :
    EGFR/CDK2-IN-1, an inhibitor of both EGFR and CDK2, demonstrates effective cytotoxicity towards MCF7 and HepG2 cells, suggesting its potential application in
    Formule :C19H12BrClO2
    Couleur et forme :Solid
    Masse moléculaire :387.65

    Ref: TM-T72844

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Nazartinib mesylate

    CAS :
    Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR(L858R/790M) mutant).
    Formule :C27H35ClN6O5S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :591.12

    Ref: TM-T11156L

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • MDK5466

    CAS :
    MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death.
    Formule :C21H23N3OS
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :365.49

    Ref: TM-T24438

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • HIV-IN-6

    CAS :
    HIV-IN-6, an anti-HIV agent, blocks replication by targeting SFKs like Hck involved with Nef protein.
    Formule :C20H16N4O3S
    Degré de pureté :97.78%
    Couleur et forme :Solid
    Masse moléculaire :392.43

    Ref: TM-T61793

    10mg
    46,00€
    25mg
    86,00€
    50mg
    124,00€
    100mg
    178,00€
    200mg
    250,00€
  • Lavendustin C6

    CAS :
    Lavendustin C6 is a effective tyrosine kinase inhibitor.
    Formule :C20H25NO5
    Couleur et forme :Solid
    Masse moléculaire :359.42

    Ref: TM-T25644

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • TRK II-IN-1

    CAS :
    TRK II-IN-1: potent type II TRK inhibitor; IC50s: TRKA (3.3 nM), TRKB (6.4 nM), TRKC (4.3 nM), TRKA G667C (9.4 nM); also targets FLT3, RET, VEGFR2.
    Formule :C29H31F3N8O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :564.6

    Ref: TM-T73033

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • BTK-IN-23

    CAS :
    BTK-IN-23: BTK inhibitor, IC50=12.8 nM; also blocks BLX (35.6 nM), BMX (5.7 nM); better selectivity than Ibrutinib.
    Formule :C27H28N6O2
    Couleur et forme :Solid
    Masse moléculaire :468.55

    Ref: TM-T73276

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • SMU-B

    CAS :
    SMU-B is a well-tolerated c-Met/ALK dual inhibitor.
    Formule :C26H25Cl2FN4O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :515.41

    Ref: TM-T24809

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • EGFR-IN-88

    CAS :
    EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis
    Formule :C22H18Cl2N4O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :473.37

    Ref: TM-T79694

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • BAY 2476568

    CAS :
    BAY 2476568 is a selective and potent EGFR inhibitor that acts on both wild-type EGFR (IC50 <0.2 nM) and mutant EGFR (IC50 <0.2 nM).
    Formule :C24H27FN4O4
    Couleur et forme :Solid
    Masse moléculaire :454.49

    Ref: TM-T62795

    25mg
    1.998,00€
    50mg
    2.602,00€
  • FGFR4-IN-5

    CAS :
    FGFR4-IN-5: potent, selective FGFR4 inhibitor, IC50 6.5 nM, strong in vivo anti-tumor effect, for liver cancer research.
    Formule :C23H23Cl2N5O5
    Couleur et forme :Solid
    Masse moléculaire :520.37

    Ref: TM-T37425

    25mg
    1.504,00€
    50mg
    1.963,00€
    100mg
    2.520,00€
  • DPPY

    CAS :
    DPPY inhibits EGFR, BTK, JAK3 (IC50<10 nM), curbs B-cell lymphoma growth, and may be studied for IPF treatment.
    Formule :C25H26ClN7O3
    Couleur et forme :Solid
    Masse moléculaire :507.97

    Ref: TM-T63486

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€