Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(167 produits)
- Bcr-Abl(118 produits)
- EGFR(581 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2386 produits trouvés pour "Angiogenèse"
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PDGFRα/FLT3-ITD-IN-1
CAS :PDGFRα/FLT3-ITD-IN-1 are potent inhibitors of PDGFRα/FLT3, and their IC50 values are greater than 0.036 and 0.003 μM, respectively.Formule :C27H39N9OCouleur et forme :SolidMasse moléculaire :505.66Ebselen oxide
CAS :Ebselen oxide (EB-2) is a HER2 inhibitor with antibacterial and antifungal activity and has shown cytoprotective effects against HN2 in vitro.Formule :C13H9NO2SeDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :290.18KRC-108
CAS :KRC-108 is a potent kinase inhibitor targeting Ron, Flt3, TrkA, and c-Met with strong anti-proliferative effects on various cancer cells.Formule :C20H20N6OCouleur et forme :SolidMasse moléculaire :360.41EGFR/HER2-IN-9
CAS :EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFRFormule :C25H25ClFN5O4Couleur et forme :SolidMasse moléculaire :513.95YF-452
CAS :YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling.Formule :C24H26BrN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.39Multi-kinase-IN-3
CAS :Multi-kinase-IN-3 (compound 2) is a potent inhibitor of angiokinase and inhibits VEGFR-2 (IC50: 58.3 nM) and PDGFRβ (IC50: 55 nM).Formule :C33H33N5O3Couleur et forme :SolidMasse moléculaire :547.65VEGFR-2-IN-30
VEGFR-2-IN-30: VEGFR-2 inhibitor, IC50 66 nM; blocks PDGFR, EGFR & FGFR1; halts cancer cell cycle, induces apoptosis.Formule :C28H23ClN6O4S2Couleur et forme :SolidMasse moléculaire :607.1CHMFL-ABL-053
CAS :CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.Formule :C28H26F3N7O2Couleur et forme :SolidMasse moléculaire :549.55VEGFR-2-IN-21
CAS :VEGFR-2-IN-21 is a potent inhibitor of VEGFR-2 (IC50: 0.10 μM) and exhibits anticancer effects.Formule :C28H24ClN7O3SCouleur et forme :SolidMasse moléculaire :574.05VEGFR-2-IN-22
CAS :VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.Formule :C26H24ClFN4O6Couleur et forme :SolidMasse moléculaire :542.94PDGFRα/FLT3-ITD-IN-3
CAS :PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/FLT3-ITD-IN-3 has the potential to beFormule :C26H39N9Couleur et forme :SolidMasse moléculaire :477.65SYK/JAK-IN-1
CAS :SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.Formule :C24H26N8O3Couleur et forme :SolidMasse moléculaire :474.52FGFR-IN-7
CAS :FGFR-IN-7: Oral FGFR modulator, crosses blood-brain barrier, neuroprotective, phospholipidosis-resistant, useful for neurodegeneration study.Formule :C16H21ClF2N4O2Couleur et forme :SolidMasse moléculaire :374.81EMI56
CAS :EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1].Formule :C21H20N2O3Couleur et forme :SolidMasse moléculaire :348.4EGFR-IN-39
CAS :EGFR-IN-39, an acrylamide, is a potent EGFR inhibitor and antitumor agent targeting NSCLC with low toxicity. See WO2021185348A1 for details.Formule :C24H25ClN6O3Couleur et forme :SolidMasse moléculaire :480.95EMI48
CAS :EMI48, a derivative of EMI1, exhibits increased efficacy against mutant EGFR compared to EMI1. It specifically inhibits EGFR triple mutants [1].Formule :C21H20N2O3Couleur et forme :SolidMasse moléculaire :348.4Lck Inhibitor III
CAS :Lck Inhibitor III, a potent inhibitor of Lck, exhibits an IC50 value of 867 nM.Formule :C25H30N6O4Couleur et forme :SolidMasse moléculaire :478.54K 00546
CAS :K00546 inhibits CDK1/cyclin B (IC50: 0.6 nM), CDK2/cyclin A (IC50: 0.5 nM), CLK1 (IC50: 8.9 nM), and CLK3 (IC50: 29.2 nM).Formule :C15H13F2N7O2S2Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :425.44EGFR/BRAFV600E-IN-1
CAS :EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).Formule :C24H24ClN3O3Couleur et forme :SolidMasse moléculaire :437.92PF-00956980
CAS :PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.Formule :C18H26N6OCouleur et forme :SolidMasse moléculaire :342.44Debio 0617B
CAS :Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.Formule :C28H23ClF3N7O2Couleur et forme :SolidMasse moléculaire :581.98EGFR/C797S-IN-1
CAS :EGFR/C797S-IN-1: Potent EGFR-C797S inhibitor, IC50 of 0.128 µM, dose-dependent p-EGFR suppression, anti-tumor properties.Formule :C28H30N4O3Couleur et forme :SolidMasse moléculaire :470.56pan-HER-IN-2
CAS :pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71Y 11
CAS :focal adhesion kinase (FAK) inhibitorFormule :C8H17BrN4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.15BTK-IN-22
CAS :BTK-IN-22 is a selective BTK inhibitor with IC50 of 0.9 nM; also targets BLX, BMX (IC50s: 1.4, 1.2 nM); better selectivity than Ibrutinib.Formule :C26H26N6O2Couleur et forme :SolidMasse moléculaire :454.52GW694590A
CAS :GW694590A (UNC10112731) functions as a MYC protein stabilizer that enhances the levels of endogenous MYC protein. It also acts on receptor tyrosine kinases, inhibiting DDR2, KIT, and PDGFRα by 81%, 68%, and 67% at a concentration of 1 μM, respectively. As a protein kinase inhibitor, GW694590A affects both ATP-dependent and ATP-independent luciferases, potentially influencing the Fluc reporter gene [1].Formule :C22H19N5O4Couleur et forme :SolidMasse moléculaire :417.42EGFR-IN-63
CAS :EGFR- IN-63 is an EGFR inhibitor with an IC50 value of 0.096 μM. EGFR- IN-63 exhibited anticancer effects on MCF-7 cells (IC50: 2.49 μM).Formule :C20H12BrN5SCouleur et forme :SolidMasse moléculaire :434.31EGFR mutant-IN-2
CAS :EGFR mutant-IN-2 (Compound D51) is an inhibitor of EGFR mutants, specifically targeting EGFR L858R/T790M/C797S and EGFR del19/T790M/C797S mutants with IC50 values of 14 nM and 62 nM, respectively. This compound exhibits favorable pharmacokinetic (PK) parameters, safety properties, in vivo stability, and demonstrates antitumor activity [1].Formule :C27H27F3N6O2SCouleur et forme :SolidMasse moléculaire :556.6PHA-680626
CAS :PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).Formule :C23H26N6O2SCouleur et forme :SolidMasse moléculaire :450.56CGP52411
CAS :CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Formule :C20H15N3O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :329.35GDC-4379
CAS :GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Formule :C21H18ClF2N7O3Couleur et forme :SolidMasse moléculaire :489.86Luxeptinib
CAS :Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.Formule :C25H17F4N5O2Couleur et forme :SolidMasse moléculaire :495.43BCR-ABL-IN-5
CAS :BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.Formule :C25H21Cl2N5O2Couleur et forme :SolidMasse moléculaire :494.37CJ-2360
CAS :CJ-2360 is a potent ALK inhibitor, effective on wild-type and various mutants, with IC50 values ranging from 2.2 to 8.9 nM, also targeting 468 kinases.Formule :C27H30FN5O2Couleur et forme :SolidMasse moléculaire :475.56JAK-IN-28
CAS :JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].Formule :C20H18ClN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.86α7 nAchR-JAK2-STAT3 agonist 1
CAS :α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).Formule :C25H30O6Couleur et forme :SolidMasse moléculaire :426.5AGL 2043
CAS :AGL 2043 is a potent, reversible, ATP-competitive inhibitor of type III receptor tyrosine kinases.Formule :C15H12N4SCouleur et forme :SolidMasse moléculaire :280.35JAK3/BTK-IN-1
CAS :JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two importantFormule :C25H28N8ODegré de pureté :97.89%Couleur et forme :SolidMasse moléculaire :456.54Lck-IN-1
CAS :Lck-IN-1 is a potent inhibitor of lymphocyte protein tyrosine kinase (Lck) [1].Formule :C14H15N5Couleur et forme :SolidMasse moléculaire :253.3Rac-ZINC4085554
CAS :Compound 1T-0219 (SC) is a blocker of AKT1-FAK interaction reducing the stimulation of FAK phosphorylation in response to extracellular pressure in human SW620
Formule :C20H19N3O7Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :413.38JNJ28871063 hydrochloride
CAS :ErbB receptor family inhibitorFormule :C24H28Cl2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.42VEGFR-2-IN-23
CAS :VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Formule :C22H15N5O2Couleur et forme :SolidMasse moléculaire :381.39VI 16832
CAS :VI 16832 is a broad-spectrum Type I kinase inhibitor used to quantify relative kinase abundance and study signaling across SILAC-encoded cancer cell lines.Formule :C22H25N5O2Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :391.47EGFR-IN-2
CAS :EGFR-IN-2 is a oral and mutation-selective EGFR inhibito,NSCLC, with high selectivity for resistant single and double mutant T790M.Formule :C26H33N9O3SDegré de pureté :98.52% - 99.79%Couleur et forme :SolidMasse moléculaire :551.66AFG210
CAS :AFG210 is a novel first-generation “type II” FLT3 inhibitor.Formule :C19H14F3N3O2Couleur et forme :SolidMasse moléculaire :373.33LDC0496
CAS :LDC0496: Potent EGFR/Her2 exon 20 inhibitor; selective for wild-type EGFR, kinase-specific.Formule :C32H35N5O3Couleur et forme :SolidMasse moléculaire :537.65EGFR/HER2/TS-IN-1
CAS :EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.Formule :C24H15N5O4S2Couleur et forme :SolidMasse moléculaire :501.54MAX-40279
CAS :MAX-40279 is a potent, dual FLT3 kinase and FGFR kinase inhibitor. MAX-40279 has potential for acute myeloid leukemia (AML) studies.Formule :C22H23FN6OSCouleur et forme :SolidMasse moléculaire :438.52EGFR/HER2/CDK9-IN-1
CAS :EGFR/HER2/CDK9-IN-1 is a potent inhibitor (IC50: EGFR 90.17 nM, HER2 131.39 nM, CDK9 67.04 nM) with notable anti-tumor activity.Formule :C23H21N3O3S2Couleur et forme :SolidMasse moléculaire :451.56BCR-ABL1-IN-1
CAS :BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.Formule :C18H12F3N3O2Couleur et forme :SolidMasse moléculaire :359.3BIBX 1382 Dihydrochloride
CAS :BIBX 1382 Dihydrochloride blocks Lassa/Ebola entry, aids in studying virus-host interactions, and hints at kinase targets for therapy.Formule :C18H21Cl3FN7Couleur et forme :SolidMasse moléculaire :460.76PDZ1i
CAS :PDZ1i: potent MDA-9/Syntenin inhibitor; crosses blood-brain barrier; targets GBM, FAK, EGFRvIII; lowers MMP secretion.Formule :C28H26N8O4Couleur et forme :SolidMasse moléculaire :538.56Con B-1
CAS :ConB-1 is a potent and selective ALK inhibitor with low toxicity to normal cells .Formule :C38H52ClN7O6SCouleur et forme :SolidMasse moléculaire :770.38MAX-40279 hydrochloride
CAS :MAX-40279 HCl: potent FLT3/FGFR inhibitor; potential in AML research.Formule :C22H24ClFN6OSCouleur et forme :SolidMasse moléculaire :474.98VEGFR-2/BRAF-IN-2
VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.Formule :C26H21ClF3N5O3S2Couleur et forme :SolidMasse moléculaire :608.05BSc5371
CAS :BSc5371: Irreversible FLT3 inhibitor; Kds 0.83-5.8 nM for various FLT3 mutants including wild type.Formule :C24H31N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.6EGFR/HER2/TS-IN-2
CAS :EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).Formule :C26H21N7OS2Couleur et forme :SolidMasse moléculaire :511.62Adhesamine
CAS :Adhesamine, a dumbbell molecule, enhances cell adhesion, growth, neuron differentiation, and survival via MAPK/FAK.Formule :C24H32Cl4N8O2S2Couleur et forme :SolidMasse moléculaire :670.51PD173952
CAS :PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.Formule :C24H21Cl2N5O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :482.36PDGFRα/FLT3-ITD-IN-2
CAS :PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM).Formule :C28H41N9OCouleur et forme :SolidMasse moléculaire :519.68FAK inhibitor 5
CAS :FAK inhibitor 5 is a novel allosteric FAK inhibitor, with IC50 values in the low micromolar range.Formule :C20H21N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.46Nimotuzumab
CAS :Nimotuzumab is a humanized therapeutic monoclonal antibody against epidermal growth factor receptor EGFR).Degré de pureté :95.00% - 98.5% (SDS-PAGE); 96.4% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :147.64 kDaS116836
CAS :S116836 is a tyrosine kinase inhibitor.Formule :C27H21F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.49FGFR3-IN-5
CAS :FGFR3-IN-5: potent, selective FGFR3 inhibitor. IC50: 3 nM FGFR3, 44 nM FGFR2, 289 nM FGFR1. For cancer research.Formule :C24H24FN7O3Couleur et forme :SolidMasse moléculaire :477.49VEGFR-2-IN-28
CAS :VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.Formule :C26H17N7O7Couleur et forme :SolidMasse moléculaire :539.46ENMD-1198
CAS :ENMD-119 is a 2-methoxyestradiol analog with antiproliferative and antiangiogenic activity. It is suitable for inhibiting HIF-1α and STAT3 in human HCC cells.Formule :C20H25NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :311.42BLK degrader 1
CAS :BLK degrader 1 is a BLK degrader with anticancer activity for cancer research.Formule :C32H25F3N6O2Degré de pureté :99.22% - 99.24%Couleur et forme :SolidMasse moléculaire :582.58WDR5-IN-4
CAS :WIN site inhibitor 1 is a WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5) inhibitor (Kd: 0.1 nM), with anti-cancer activity.Formule :C25H22Cl2FN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.38LS-104
CAS :LS-104 is a JAK2 inhibitor.Formule :C19H16N2O3Couleur et forme :SolidMasse moléculaire :320.34Glufanide disodium
CAS :Glufanide disodium is an immunomodulator.Formule :C16H17N3O5Na2Couleur et forme :SolidMasse moléculaire :377.3c-Met-IN-11
CAS :c-Met-IN-11 is a potent inhibitor of c-MET (IC50: 41.4 nM) and VEGFR-2 (IC50: 71.1 nM).Formule :C30H20F2N4O3Couleur et forme :SolidMasse moléculaire :522.5SB-220025 trihydrochloride
CAS :SB-220025 trihydrochloride is an effective and specific human p38 mitogen-activated protein kinase inhibitor.Formule :C18H22Cl3FN6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.77WB-308
CAS :WB-308 is an EGFR inhibitor that acts by decreasing NSCLC cell proliferation and colony formation and causing G2/M arrest and apoptosis.Formule :C19H17FN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.35Tyrphostin AG 568
CAS :Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.Formule :C13H9N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.24KRCA-0713
CAS :KRCA-0713 is a ALK inhibitor.Formule :C26H32ClN5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :530.08BGB659
CAS :BGB659 is effective inhibitor of RAF.Formule :C29H29F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.564-DAMP
CAS :4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.Formule :C21H26INO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.34FLT3-IN-17
CAS :FLT3-IN-17: FAK inhibitor, IC50 of 12 nM; blocks CYPs, FLT3 mutants; IC50 <0.5 nM for D835Y in cancer studies.Formule :C23H24N6O2S2Couleur et forme :SolidMasse moléculaire :480.61HP1328
CAS :HP1328: potent FLT3/ITD inhibitor, reduces leukemia, extends survival in mice, belongs to benzoimidazole family.Formule :C23H23N3O3Couleur et forme :SolidMasse moléculaire :389.45PF-06465469
CAS :PF-06465469, a covalent ITK and BTK inhibitor (IC₅₀ = 2 nM), suppresses CXCL12-mediated migration and decreases PD-1/LAG-3 for leukemia and lymphoma research.Formule :C30H33N7O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.63EGA
CAS :EGA blocks the entry of a variety of other acid-dependent bacterial toxins and viruses into mammalian cells and can be used to treat infectious diseases.Formule :C16H16BrN3ODegré de pureté :98% - 99.6%Couleur et forme :SolidMasse moléculaire :346.22TUL01101
CAS :TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.Formule :C22H25F2N5O2Couleur et forme :SolidMasse moléculaire :429.46JG26
CAS :JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively,Formule :C19H22Br2N4O6SDegré de pureté :98.79% - 99.08%Couleur et forme :SolidMasse moléculaire :594.27YLT192
CAS :YLT192 is an orally active and bioavailable VEGFR2 inhibitor. It also has potent antiangiogenic activity and antitumor efficacy.Formule :C21H19N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.39QL-X-138
CAS :QL-X-138: Dual BTK/MNK inhibitor; covalent to BTK, IC50=9.4 nM; non-covalent to MNK1/2, IC50=107.4/26 nM; dengue virus 2 IC50=3.5 μM; for B-cell malignancies.
Formule :C25H19N5O2Degré de pureté :98.82% - 99.50%Couleur et forme :SolidMasse moléculaire :421.45DS21360717
CAS :DS21360717 is an effective oral tyrosine kinase inhibitor with anticancer activity and IC50 of 0.49 nM.Formule :C21H23N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.45Atopaxar
CAS :Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formule :C29H38FN3O5Degré de pureté :97.07% - 98.07%Couleur et forme :SolidMasse moléculaire :527.63(2R,5S)-Ritlecitinib
CAS :(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].Formule :C15H19N5OCouleur et forme :SolidMasse moléculaire :285.34JS25
CAS :JS25, a selective BTK inhibitor, inactivates it with a 5.8 nM IC50, halts cancer cell growth, induces death, and aids against lymphoma.Formule :C29H24N4O4SCouleur et forme :SolidMasse moléculaire :524.59Povorcitinib
CAS :Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).Formule :C23H22F5N7OCouleur et forme :SolidMasse moléculaire :507.469FAK-IN-5
CAS :FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.Formule :C29H29ClF3N3O4Couleur et forme :SolidMasse moléculaire :576.01AhR modulator-1
CAS :AhR modulator-1: orally active, selective, inhibits metastasis and prostatic VEGF, anti-estrogenic in rat uterus.Formule :C13H7Cl3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :285.55E-4177
CAS :E-4177 is an angiotensin II type 1 receptor (AT1R) antagonist and can be used to study cardiovascular diseases.Formule :C24H21N3O2Degré de pureté :98.67% - 99.57%Couleur et forme :SolidMasse moléculaire :383.44PD 173955-Analog1
CAS :PD 173955-Analog1 is a potent c-Src inhibitor known to have activity against a variety of cancers including colon, lung, head and neck carcinoma.Formule :C21H14Cl2N4O3Couleur et forme :SolidMasse moléculaire :441.27MG-262
CAS :MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].Formule :C25H42BN3O6Couleur et forme :SolidMasse moléculaire :491.43FLT3/CDK4-IN-1
CAS :FLT3/CDK4-IN-1: Oral FLT3 (7 nM IC50) & CDK4 (11 nM IC50) inhibitor with strong in vivo anti-cancer properties.Formule :C25H28F2N8Couleur et forme :SolidMasse moléculaire :478.54FLT3-IN-11
CAS :FLT3-IN-11, an oral FLT3 kinase inhibitor: potent, selective, IC50 - wild-type 7.22 nM, FLT3-D835Y 4.95 nM, anti-AML IC50 3.2 nM for MV4-11.Formule :C20H25F3N6OCouleur et forme :SolidMasse moléculaire :422.45GDC-0834 S-enantiomer
CAS :GDC-0834, the S-enantiomer, is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK).Formule :C33H36N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :596.74BI1002494
CAS :BI1002494 is an effective and selective Syk inhibitor.Formule :C23H25N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.46(E/Z)-AG490
CAS :(E/Z)-AG490 is a racemic mix of (E)- and (Z)-isomers; it inhibits tyrosine kinase, EGFR, Stat-3, and JAK2/3.Formule :C17H14N2O3Couleur et forme :SolidMasse moléculaire :294.3
