Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(166 produits)
- Bcr-Abl(117 produits)
- EGFR(581 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2379 produits trouvés pour "Angiogenèse"
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HIF-IN-1
CAS :HIF-IN-1 is a inhibitor of hypoxia-inducible factor, which is associated with tumor and cancer cell proliferation and inhibits HIF-1α protein aggregation.Formule :C17H12N2ODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :260.29Ifidancitinib
CAS :Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.Formule :C20H18FN5O3Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :395.39PND-1186 hydrochloride
CAS :PND-1186 hydrochloride (VS-4718 hydrochloride) is a highly specific, reversible and potent inhibitor of FAK (IC50: 1.5 nM), which can selectively induceFormule :C25H27ClF3N5O3Couleur et forme :SolidMasse moléculaire :537.97Naphazoline nitrate
CAS :Naphazoline nitrate: α1-adrenergic agonist, induces autophagy, necrosis in cancer cells, inhibits differentiation, treats congestion and eye issues.Formule :C14H15N3O3Degré de pureté :98%Couleur et forme :White Crystalline Powder White SolidMasse moléculaire :273.29Tyrphostin 8
CAS :Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits proteinFormule :C10H6N2ODegré de pureté :97%Couleur et forme :SolidMasse moléculaire :170.17Sunitinib-d10
CAS :Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).Formule :C22H27FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.54BI-4142
CAS :BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.Formule :C28H27N9O2Degré de pureté :97.21% - 98.09%Couleur et forme :SolidMasse moléculaire :521.57Ref: TM-T63643
1mg57,00€5mg120,00€10mg177,00€25mg356,00€50mg537,00€100mg803,00€200mg1.341,00€1mL*10mM (DMSO)138,00€IBT6A hydrochloride
CAS :IBT6A hydrochloride: Ibrutinib impurity, Btk inhibitor IC50: 0.5 nM, used in dimer/adduct synthesis.Formule :C22H23ClN6OCouleur et forme :SolidMasse moléculaire :422.91(Z)-Orantinib
CAS :(Z)-Orantinib ((Z)-SU6668) is an orally active ATP-competitive inhibitor of Flk-1/KDR, PDGFRβ, and FGFR1, acting as a potent anti-angiogenic and anti-tumor agent.Formule :C18H18N2O3Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :310.35Aflibercept
CAS :Aflibercept has a wide range of applications in life science related research.Couleur et forme :LiquidErlotinib-d6 hydrochloride
CAS :Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Formule :C22H24ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.93QL47
CAS :QL47 acts as an inhibitor of viral translation and a BTK inhibitor with antiviral activity against dengue virus and can be used in the study of lymphoma.Formule :C27H21N5O2Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :447.49Ponatinib-d8
CAS :Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Formule :C29H27F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.61Nilotinib-d6
CAS :Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.Formule :C28H22F3N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.55SU11652
CAS :SU11652 is an effective and competitive receptor tyrosine kinase (RTK) inhibitor, including VEGFR, FGFR, PDGFR, and Kit.Formule :C22H27ClN4O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :414.93Tucatinib hemiethanolate
CAS :Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.Formule :C54H54N16O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :1007.11(E/Z)-Zotiraciclib hydrochloride
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent inhibitor of CDK2, JAK2, and FLT3.Formule :C23H25ClN4OCouleur et forme :SolidMasse moléculaire :408.93Disitamab
CAS :Disitamab (RC48-0) is a humanized anti-HER2 monoclonal antibody used in ADC synthesis.Degré de pureté :95.00%Couleur et forme :LiquidMasse moléculaire :144.16 kDaAtinvicitinib
CAS :Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.Formule :C16H17FN6O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :360.35Ref: TM-T39646
1mg138,00€5mg334,00€10mg550,00€25mg1.063,00€50mg1.738,00€100mg2.547,00€1mL*10mM (DMSO)264,00€LDN-193189 Tetrahydrochloride
CAS :LDN193189 is a BMPI receptor inhibitor, blocking ALK2 and ALK3 effectively, while weak on ALK4, ALK5, ALK7.Formule :C25H26Cl4N6Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :552.33Poseltinib
CAS :Poseltinib is an oral, irreversible BTK inhibitor (IC50 1.95 nM) with higher selectivity over BMX, TEC, and TXK, blocking BCR, FcR, and TLR signaling.Formule :C26H26N6O3Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :470.52Ref: TM-T4413
2mg34,00€5mg49,00€10mg75,00€25mg146,00€50mg260,00€100mg409,00€200mg590,00€1mL*10mM (DMSO)50,00€NX-5948
CAS :NX-5948 (BTK-IN-24) is a PROTAC-type BTK degrader with anti-inflammatory and anticancer activities, inhibiting B cell activation.Formule :C42H54N12O5Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :806.96GW2974
CAS :GW2974, Oral EGFR/ErbB2 dual inhibitor, inhibits glioblastoma multiforme (GBM) cell invasion and tumor growth.Formule :C23H21N7Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :395.46DTP3
CAS :DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formule :C26H35N7O5Couleur et forme :SolidMasse moléculaire :525.6Flurandrenolide
CAS :Flurandrenolide is a corticosteroid with anti-inflammatory effects that activates EGFR (EC50=23 nM).Formule :C24H33FO6Couleur et forme :Crystals From Acetone + Hexane SolidMasse moléculaire :436.51KG-548
CAS :KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1α, inhibiting lactate production, and can be used in cancer research.Formule :C9H4F6N4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :282.15CHZ868
CAS :CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formule :C22H19F2N5O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :423.42SM1-71
CAS :SM1-71 is a TAK1 inhibitor that inhibits MKNK2 and RSK2.SM1-71 acts as a kinase probe with anticancer activity.Formule :C24H26ClN7ODegré de pureté :96%Couleur et forme :SolidMasse moléculaire :463.96A-770041
CAS :A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Formule :C34H39N9O3Degré de pureté :99.23% - 99.86%Couleur et forme :SolidMasse moléculaire :621.73Ref: TM-T14074
2mg70,00€5mg104,00€10mg170,00€25mg384,00€50mg652,00€100mg1.018,00€200mg1.350,00€1mL*10mM (DMSO)142,00€Cediranib maleate
CAS :Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.Formule :C29H31FN4O7Couleur et forme :SolidMasse moléculaire :566.58Ilunocitinib
CAS :Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Formule :C17H17N7O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :383.43Ref: TM-T38571
1mg92,00€5mg230,00€10mg356,00€25mg713,00€50mg1.189,00€100mg1.791,00€200mg2.412,00€1mL*10mM (DMSO)251,00€Asciminib hydrochloride
CAS :Asciminib hydrochloride is a STAMP inhibitor targeting the ABL myristoyl pocket, applied in Ph+ CML research for selective oncogenic signaling modulation.Formule :C20H19Cl2F2N5O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :486.3Ref: TM-T63226
1mg57,00€5mg130,00€10mg177,00€25mg289,00€50mg409,00€100mg620,00€1mL*10mM (DMSO)138,00€BPR1K871
CAS :BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values ofFormule :C25H28ClN7O2SCouleur et forme :SolidMasse moléculaire :526.05Tetrac
CAS :Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blockingFormule :C14H8I4O4Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :747.83Osimertinib dimesylate
CAS :Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Formule :C30H41N7O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :691.82Lanraplenib succinate
CAS :Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formule :C58H68N18O14Couleur et forme :SolidMasse moléculaire :1241.294Mavelertinib
CAS :Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Formule :C18H22FN9O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :415.42Surfen dihydrochloride
CAS :Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a heparin sulfate antagonist with antimicrobial properties and inhibits blockade of signaling.Formule :C21H22Cl2N6ODegré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :445.35Neratinib maleate
CAS :Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Formule :C34H33ClN6O7Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :673.11Regorafenib-d3
CAS :Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.Formule :C21H15ClF4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.83NSC 12
CAS :NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.Formule :C24H34F6O3Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :484.52Zanubrutinib-d5
Zanubrutinib-d5 (BGB-3111-d5) is a deuterium-labeled Zanubrutinib, an orally available Bruton's tyrosine kinase inhibitor for the study of B-cell malignancies.Formule :C27H29N5O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :476.58Ribociclib-d6
CAS :Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.Formule :C23H30N8OCouleur et forme :SolidMasse moléculaire :440.57Lck inhibitor 2
CAS :Lck inhibitor 2 blocks tyrosine kinases LCK, BTK, LYN, SYK, TXK with IC50s: Lck 13nM, Btk 9nM/26nM, Lyn 3nM, Txk 2nM.Formule :C18H17N5O2Couleur et forme :SolidMasse moléculaire :335.36Erlotinib-d6
CAS :Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .Formule :C22H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.47Brivanib
CAS :Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormule :C19H19FN4O3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :370.38Ref: TM-T6036
1mg44,00€5mg94,00€10mg137,00€25mg245,00€50mg355,00€100mg530,00€200mg772,00€1mL*10mM (DMSO)92,00€N-piperidine Ibrutinib hydrochloride
CAS :N-piperidine Ibrutinib hydrochloride is a BTK inhibitor that inhibits WT BTK and C481S BTK , which inhibits the growth and proliferation of cancer cells.Formule :C22H23ClN6ODegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :422.91SB1317
CAS :SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).Formule :C23H24N4ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :372.46Gefitinib-d8
CAS :Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8 is a deuterium labeled Gefitinib.Formule :C22H24ClFN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.95Imatinib-d8
CAS :Imatinib-d8 (STI571 D8) is a 2H-labeled form of Imatinib. Imatinib is a multi-target receptor tyrosine kinase inhibitor with antitumor activity.Formule :C29H23D8N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.65Pazopanib-d6
CAS :Pazopanib-d6 is a deuterated compound of Pazopanib.Formule :C21H17D6N7O2SCouleur et forme :SolidMasse moléculaire :443.56Iruplinalkib
CAS :Iruplinalkib (WX-0593) is an orally active, selective and potent ALK and ROS1 tyrosine kinase inhibitor with anticancer activity for use in the study of non-small cell lung cancer.Formule :C29H38ClN6O2PDegré de pureté :97.38% - 99.29%Couleur et forme :SolidMasse moléculaire :569.08Momelotinib sulfate
CAS :Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.Formule :C23H26N6O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :610.62Rociletinib hydrobromide
CAS :Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Formule :C27H29BrF3N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :636.46(3S,4S)-PF-06459988
CAS :(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Formule :C19H22ClN7O3Couleur et forme :SolidMasse moléculaire :431.88Elsubrutinib
CAS :Elsubrutinib (ABBV-105) is an orally active, selective, and irreversible BTK inhibitor with an IC50 of 0.18 μM for the catalytic domain of BTK.Formule :C17H19N3O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :297.36Ref: TM-T39130
1mg145,00€5mg250,00€10mg340,00€25mg573,00€50mg879,00€100mg1.314,00€1mL*10mM (DMSO)356,00€Trichilinin D
CAS :Trichilinin D is a natural product that can be used in related research in the field of life sciences. Its product number is TN8637.Formule :C37H44O8Masse moléculaire :616.74iHCK-37
CAS :iHCK-37 (ASN05260065) is an Hck inhibitor with antitumor activity and blocks HIV-1 replication, used in chronic myelogenous leukemia (CML) research.Formule :C30H32N4O2S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :544.73Rilematovir
CAS :Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.Formule :C21H20ClF3N4O3SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :500.92Bleximenib oxalate
CAS :Bleximenib oxalate (Menin-MLL inhibitor 24 oxalate) is a menin-MLL inhibitor that blocks the binding of the menin-KMT2A complex to chromatin at gene promoters.Formule :C34H52FN7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :689.82FLT3-IN-16
CAS :FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.Formule :C15H15N3O2SDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :301.36Ref: TM-T9843
2mg34,00€5mg52,00€10mg86,00€25mg172,00€50mg260,00€100mg369,00€200mg487,00€1mL*10mM (DMSO)58,00€Tirbanibulin dihydrochloride
CAS :Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formule :C26H31Cl2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.45Afatinib D6
CAS :Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.Formule :C24H25ClFN5O3Couleur et forme :SolidMasse moléculaire :491.98GDC-0834
CAS :GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 μM in mouse andFormule :C33H36N6O3SCouleur et forme :SolidMasse moléculaire :596.74AP23846
CAS :AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.Formule :C24H34N5OPDegré de pureté :97.83%Couleur et forme :SolidMasse moléculaire :439.53Conteltinib tetrahydrochloride
Conteltinibtetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride form of Conteltinib. It acts as an inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. When used in combination with Cabozantinib, Conteltinib tetrahydrochloride exhibits a synergistic antitumor effect.Formule :C32H49Cl4N9O3SCouleur et forme :SolidMasse moléculaire :781.667EW-7195
CAS :EW-7195 inhibits ALK5/TGFβR1 (>300x selective over p38α) with 4.83 nM IC50, blocking TGF-β1 signaling, EMT, and breast cancer lung metastasis.
Formule :C23H18N8Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :406.44SU14813 maleate
CAS :SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Formule :C27H31FN4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :558.56AV-412 free base
CAS :AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Formule :C27H28ClFN6OCouleur et forme :SolidMasse moléculaire :507Imatinib D4
CAS :Imatinib D4 is a deuterium-labeled Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, PDGFR, v-Abl, and c-kit kinase activity.Formule :C29H31N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.63Pentagamavunon-1
CAS :PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Formule :C23H24O3Couleur et forme :SolidMasse moléculaire :348.43N-Desethyl Sunitinib
CAS :N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,Formule :C20H23FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.42Cevidoplenib dimesylate hydrochloride
CAS :Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.Formule :C90H132Cl5N27O12Degré de pureté :97.52%Couleur et forme :SolidMasse moléculaire :1957.9(S)-Sunvozertinib
CAS :(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Formule :C29H35ClFN7O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :584.08Onatasertib
CAS :Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formule :C21H27N5O3Degré de pureté :99.14% - 99.93%Couleur et forme :SolidMasse moléculaire :397.47Ibrutinib deacryloylpiperidine
CAS :Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Formule :C17H13N5ODegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :303.32Derazantinib dihydrochloride
CAS :Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.Formule :C29H31Cl2FN4OCouleur et forme :SolidMasse moléculaire :541.49R-268712
CAS :R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.Formule :C20H18FN5ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :363.39Ref: TM-T16708
1mg44,00€5mg93,00€10mg130,00€25mg250,00€50mg378,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)92,00€TX1-85-1
CAS :TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Formule :C32H36N8O3Degré de pureté :97.16% - 98.12%Couleur et forme :SolidMasse moléculaire :580.68JCN037
CAS :JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).Formule :C16H11BrFN3O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :376.18Nastorazepide
CAS :Nastorazepide is a selective, orally available antagonist of gastrin/cholecystokinin 2 (CCK-2) receptor with potential antineoplastic activity.Formule :C29H36N4O5Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :520.62Tolimidone
CAS :Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
Formule :C11H10N2O2Degré de pureté :99.85% - 99.85%Couleur et forme :SolidMasse moléculaire :202.21CP-673451
CAS :CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormule :C24H27N5O2Degré de pureté :99.62% - 99.88%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T6091
1mg49,00€2mg63,00€5mg90,00€10mg170,00€25mg334,00€50mg512,00€100mg737,00€500mg1.521,00€1mL*10mM (DMSO)108,00€Vadimezan
CAS :Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity.Formule :C17H14O4Degré de pureté :97.38% - 99.8%Couleur et forme :SolidMasse moléculaire :282.29Ref: TM-T6273
2mg39,00€5mg58,00€10mg93,00€25mg172,00€50mg268,00€100mg401,00€200mg580,00€1mL*10mM (DMSO)89,00€CNX-774
CAS :CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).Formule :C26H22FN7O3Degré de pureté :97.35% - 99.11%Couleur et forme :SolidMasse moléculaire :499.5Ref: TM-T2302
1mg38,00€2mg50,00€5mg84,00€10mg119,00€25mg222,00€50mg369,00€100mg537,00€500mg1.161,00€1mL*10mM (DMSO)88,00€Pelitinib
CAS :Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formule :C24H23ClFN5O2Degré de pureté :98.37% - 99.84%Couleur et forme :Off-White SolidMasse moléculaire :467.92Altiratinib
CAS :Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Formule :C26H21F3N4O4Degré de pureté :99.67% - 99.75%Couleur et forme :SolidMasse moléculaire :510.46PF 477736
CAS :PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formule :C22H25N7O2Degré de pureté :97.58% - 99.94%Couleur et forme :SolidMasse moléculaire :419.48N-piperidine Ibrutinib
CAS :N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively.Formule :C22H22N6ODegré de pureté :96.65%Couleur et forme :SolidMasse moléculaire :386.45GMB-475
CAS :GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.Formule :C43H46F3N7O7SDegré de pureté :98.78% - >99.99%Couleur et forme :SolidMasse moléculaire :861.93Ref: TM-T8488
1mg50,00€2mg66,00€5mg99,00€10mg160,00€25mg281,00€50mg416,00€100mg600,00€200mg835,00€1mL*10mM (DMSO)152,00€Neratinib
CAS :Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formule :C30H29ClN6O3Degré de pureté :96.17% - 99.85%Couleur et forme :SolidMasse moléculaire :557.04PF-562271 besylate
CAS :PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formule :C21H20F3N7O3S·C6H6O3SDegré de pureté :97.65% - 99.01%Couleur et forme :SolidMasse moléculaire :665.66Ref: TM-T6177
1mg35,00€5mg74,00€10mg94,00€25mg138,00€50mg198,00€100mg296,00€200mg427,00€1mL*10mM (DMSO)89,00€1-NM-PP1
CAS :1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.Formule :C20H21N5Degré de pureté :98% - 98.93%Couleur et forme :White Cyrstalline SolidMasse moléculaire :331.41Ref: TM-T2153
1mg48,00€2mg63,00€5mg84,00€10mg132,00€25mg271,00€50mg505,00€100mg668,00€1mL*10mM (DMSO)90,00€Tandutinib
CAS :Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Formule :C31H42N6O4Degré de pureté :99.45% - ≥98%Couleur et forme :White SolidMasse moléculaire :562.7Coumarin-3-carboxylic acid
CAS :The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR/Formule :C10H6O4Degré de pureté :99.88%Couleur et forme :Light Brown Crystalline PowderMasse moléculaire :190.15(Rac)-JBJ-04-125-02
CAS :(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.Formule :C29H26FN5O3SDegré de pureté :97.57%Couleur et forme :SolidMasse moléculaire :543.61Ref: TM-T8872
1mg100,00€5mg205,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€1mL*10mM (DMSO)249,00€Acriflavine Hydrochloride
CAS :Acriflavine HCl is a HIF-1α inhibitor reducing PGK1, VEGF, and HIF-1α levels both in vitro and in vivo.Formule :C14H14ClN3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :259.73WHI-P180
CAS :WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formule :C16H15N3O3Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :297.31Vactosertib
CAS :Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formule :C22H18FN7Degré de pureté :98.85% - 99.81%Couleur et forme :SolidMasse moléculaire :399.42Tirbanibulin
CAS :Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53Ref: TM-T6345
1mg34,00€5mg60,00€10mg73,00€25mg142,00€50mg253,00€100mg424,00€200mg605,00€1mL*10mM (DMSO)63,00€
