Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(166 produits)
- Bcr-Abl(118 produits)
- EGFR(582 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2382 produits trouvés pour "Angiogenèse"
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AMG-47a
CAS :AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56Ilorasertib
CAS :Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54EAI045
CAS :EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formule :C19H14FN3O3SDegré de pureté :98.00% - 99.12%Couleur et forme :SolidMasse moléculaire :383.4BMS-986142
CAS :BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).Formule :C32H30F2N4O4Degré de pureté :99.44% - 99.76%Couleur et forme :SolidMasse moléculaire :572.6Ref: TM-T5138
1mg105,00€2mg165,00€5mg289,00€10mg447,00€25mg715,00€50mg964,00€100mg1.243,00€200mg1.693,00€1mL*10mM (DMSO)358,00€Pantoprazole sodium
CAS :Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Formule :C16H14F2N3NaO4SDegré de pureté :96.92% - 99.81%Couleur et forme :White To Off-White SolidMasse moléculaire :405.35Avitinib
CAS :Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Formule :C26H26FN7O2Degré de pureté :99.81% - >99.99%Couleur et forme :SolidMasse moléculaire :487.53BMS-2
CAS :BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Formule :C25H16F2N4O3Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :458.42Ref: TM-T8326
1mg67,00€2mg88,00€5mg148,00€10mg230,00€25mg430,00€50mg622,00€100mg898,00€1mL*10mM (DMSO)170,00€Gefitinib-based PROTAC 3
CAS :Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).Formule :C47H57ClFN7O8SDegré de pureté :97.29% - 98.25%Couleur et forme :SolidMasse moléculaire :934.51CL-387785
CAS :CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Formule :C18H13BrN4ODegré de pureté :99.56% - 99.62%Couleur et forme :SolidMasse moléculaire :381.23SUN11602
CAS :SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Formule :C26H37N5O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :451.6Dovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51PX-478
CAS :PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.Formule :C13H20Cl4N2O3Degré de pureté :97% - 99.79%Couleur et forme :SolidMasse moléculaire :394.12Ref: TM-T6961
1mg39,00€5mg84,00€10mg130,00€25mg193,00€50mg261,00€100mg411,00€200mg605,00€1mL*10mM (DMSO)84,00€Bisindolylmaleimide I
CAS :Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formule :C25H24N4O2Degré de pureté :97.51% - 98.75%Couleur et forme :Orange SolidMasse moléculaire :412.48TAK-632
CAS :TAK-632 is a potent pan-Raf inhibitor.Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52Agerafenib
CAS :Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.Formule :C24H22F3N5O5Degré de pureté :95.78% - 99.23%Couleur et forme :SolidMasse moléculaire :517.46Ref: TM-T2070
1mg39,00€5mg93,00€10mg124,00€25mg219,00€50mg358,00€100mg530,00€200mg757,00€1mL*10mM (DMSO)90,00€N-Desethylsunitinib hydrochloride
CAS :N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.Formule :C20H24ClFN4O2Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :406.88PP121
CAS :PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formule :C17H17N7Degré de pureté :98.45% - 99.93%Couleur et forme :SolidMasse moléculaire :319.362-(1,8-naphthyridin-2-yl)phenol
CAS :2-NP is a STAT1 enhancer.Formule :C14H10N2ODegré de pureté :99.33% - 99.82%Couleur et forme :SolidMasse moléculaire :222.24Ref: TM-T2168
5mg57,00€10mg90,00€25mg177,00€50mg281,00€100mg444,00€200mg647,00€500mg982,00€1mL*10mM (DMSO)63,00€LDN-212854
CAS :LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Formule :C25H22N6Degré de pureté :98% - 98.71%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T1900
1mg47,00€2mg62,00€5mg92,00€10mg172,00€25mg294,00€50mg439,00€100mg660,00€200mg945,00€1mL*10mM (DMSO)102,00€R112
CAS :R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formule :C16H13FN4O2Degré de pureté :99.27% - 99.84%Couleur et forme :SolidMasse moléculaire :312.3Ref: TM-T3185
1mg37,00€2mg49,00€5mg79,00€10mg117,00€25mg207,00€50mg311,00€100mg462,00€500mg973,00€1mL*10mM (DMSO)87,00€Ibrutinib
CAS :Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.Formule :C25H24N6O2Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :440.5Imatinib
CAS :Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormule :C29H31N7ODegré de pureté :99.42% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6RG13022
CAS :RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).Formule :C16H14N2O2Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :266.29Pacritinib hydrochloride
CAS :Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.Formule :C28H32N4O3·xClHCouleur et forme :SolidMidostaurin
CAS :PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formule :C35H30N4O4Degré de pureté :97.61% - >99.99%Couleur et forme :SolidMasse moléculaire :570.64Ref: TM-T3211
1mg49,00€5mg84,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€1mL*10mM (DMSO)90,00€MTX-211
CAS :MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formule :C20H14Cl2FN5O2SDegré de pureté :97.6% - >99.99%Couleur et forme :SolidMasse moléculaire :478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)170,00€TAS6417
CAS :Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€1mL*10mM (DMSO)203,00€Takeda-6d
CAS :Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.Formule :C27H19ClFN5O3SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :547.99Ref: TM-T22436
1mg92,00€2mg128,00€5mg178,00€10mg268,00€25mg439,00€50mg610,00€100mg820,00€200mg1.099,00€1mL*10mM (DMSO)243,00€OICR-9429
CAS :OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.Formule :C29H32F3N5O3Degré de pureté :97.07% - 99.93%Couleur et forme :SolidMasse moléculaire :555.59Ref: TM-T6916
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg177,00€50mg295,00€100mg475,00€1mL*10mM (DMSO)92,00€(E/Z)-Zotiraciclib
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46Ref: TM-T21503
1mg43,00€2mg56,00€5mg93,00€10mg113,00€25mg200,00€50mg330,00€100mg480,00€1mL*10mM (DMSO)90,00€AZD4547
CAS :AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.Formule :C26H33N5O3Degré de pureté :99.37% - 99.88%Couleur et forme :SolidMasse moléculaire :463.57Ref: TM-T1948
2mg37,00€5mg50,00€10mg59,00€25mg84,00€50mg107,00€100mg147,00€200mg207,00€500mg348,00€1mL*10mM (DMSO)52,00€lavendustin C
CAS :lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26Ref: TM-T4185
1mg42,00€2mg55,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€1mL*10mM (DMSO)90,00€Regorafenib mesylate
CAS :Regorafenib mesylate is an oral multi-kinase inhibitor targeting VEGFR, PDGFRβ, Kit, RET, Raf-1 with strong anti-tumor and anti-angiogenic effects.Formule :C22H19ClF4N4O6SCouleur et forme :SolidMasse moléculaire :578.92A 83-01 sodium salt
CAS :A 83-01 sodium salt inhibits ALK5, ALK4, and ALK7 kinases with IC50s: 12, 45, 7.5 nM.Formule :C25H19N5NaSCouleur et forme :SolidMasse moléculaire :444.51Masitinib
CAS :Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formule :C28H30N6OSDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :498.64AZD-3463
CAS :AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95ODM-203
CAS :ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormule :C26H21F2N5O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :505.54Ibrutinib deacryloylpiperidine
CAS :Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Formule :C17H13N5ODegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :303.32Saracatinib
CAS :Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56CP-673451
CAS :CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormule :C24H27N5O2Degré de pureté :99.62% - 99.88%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T6091
1mg49,00€2mg63,00€5mg90,00€10mg170,00€25mg334,00€50mg512,00€100mg737,00€500mg1.521,00€1mL*10mM (DMSO)108,00€NVP-AEW541
CAS :NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormule :C27H29N5ODegré de pureté :98.7% - 99.86%Couleur et forme :SolidMasse moléculaire :439.55Acalabrutinib
CAS :Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Formule :C26H23N7O2Degré de pureté :98.94% - 99.64%Couleur et forme :SolidMasse moléculaire :465.51Ref: TM-T3626
5mg44,00€10mg57,00€25mg78,00€50mg90,00€100mg144,00€200mg215,00€500mg355,00€1mL*10mM (DMSO)48,00€Ningetinib Tosylate
CAS :Ningetinib Tosylate is an orally bioavailable tyrosine kinase inhibitor with IC50s of <1.0, 1.9 and 6.7 nM for Axl, VEGFR2, and c-Met, respectively.Formule :C38H37FN4O8SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :728.79Entospletinib
CAS :Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Formule :C23H21N7ODegré de pureté :98.54% - 99.74%Couleur et forme :SolidMasse moléculaire :411.46Ref: TM-T6101
1mg35,00€2mg50,00€5mg77,00€10mg92,00€25mg166,00€50mg245,00€100mg394,00€200mg585,00€1mL*10mM (DMSO)84,00€SPHINX31
CAS :SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Formule :C27H24F3N5O2Degré de pureté :99.3% - 99.87%Couleur et forme :SolidMasse moléculaire :507.51Ref: TM-T5194
1mg40,00€5mg84,00€10mg97,00€25mg180,00€50mg269,00€100mg430,00€500mg998,00€1mL*10mM (DMSO)87,00€A-443654
CAS :A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).Formule :C24H23N5ODegré de pureté :98.04% - 99.51%Couleur et forme :SolidMasse moléculaire :397.47Ref: TM-T14072
1mg87,00€5mg178,00€10mg289,00€25mg537,00€50mg822,00€100mg1.234,00€200mg1.665,00€500mg2.457,00€1mL*10mM (DMSO)203,00€Tirbanibulin
CAS :Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53Ref: TM-T6345
1mg34,00€5mg60,00€10mg73,00€25mg142,00€50mg253,00€100mg424,00€200mg605,00€1mL*10mM (DMSO)63,00€NVP-BHG712
CAS :NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFormule :C26H20F3N7ODegré de pureté :97.32% - 98.63%Couleur et forme :SolidMasse moléculaire :503.48Ref: TM-T6348
1mg34,00€5mg74,00€10mg105,00€25mg200,00€50mg371,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)84,00€PF-562271 besylate
CAS :PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formule :C21H20F3N7O3S·C6H6O3SDegré de pureté :97.65% - 99.01%Couleur et forme :SolidMasse moléculaire :665.66Ref: TM-T6177
1mg35,00€5mg74,00€10mg94,00€25mg138,00€50mg198,00€100mg296,00€200mg427,00€1mL*10mM (DMSO)89,00€FIIN-3
CAS :FIIN-3 is an irreversible inhibitor of FGFR.Formule :C34H36Cl2N8O4Degré de pureté :97.63% - 98.92%Couleur et forme :SolidMasse moléculaire :691.61SAR131675
CAS :SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formule :C18H22N4O4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :358.39Ref: TM-T6012
1mg34,00€2mg46,00€5mg70,00€10mg105,00€25mg215,00€50mg304,00€100mg427,00€200mg587,00€1mL*10mM (DMSO)79,00€UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formule :C19H25ClN8Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :400.91Ref: TM-T2056L
1mg84,00€5mg168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€1mL*10mM (DMSO)185,00€Benidipine hydrochloride
CAS :Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.Formule :C28H32ClN3O6Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :542.03Lazertinib
CAS :Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formule :C30H34N8O3Degré de pureté :98.7% - 99.90%Couleur et forme :SolidMasse moléculaire :554.64Ref: TM-T4485
1mg46,00€2mg59,00€5mg96,00€10mg130,00€25mg215,00€50mg309,00€100mg444,00€200mg655,00€1mL*10mM (DMSO)104,00€ZINC13466751
CAS :ZINC13466751 is a potent HIF-1α/von Hippel-Lindau interaction inhibitor(IC50 = 2.0 µM).Formule :C20H21N5O2Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :363.41PD168393
CAS :PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Formule :C17H13BrN4ODegré de pureté :99.13% - 99.83%Couleur et forme :SolidMasse moléculaire :369.22Ref: TM-T6932
1mg37,00€2mg50,00€5mg63,00€10mg94,00€25mg146,00€50mg210,00€100mg294,00€1mL*10mM (DMSO)52,00€Regorafenib monohydrate
CAS :Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murineFormule :C21H17ClF4N4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :500.83Ref: TM-T1792L
5mg34,00€10mg46,00€25mg65,00€50mg94,00€100mg133,00€200mg197,00€500mg329,00€1mL*10mM (DMSO)55,00€Neratinib
CAS :Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formule :C30H29ClN6O3Degré de pureté :96.17% - 99.85%Couleur et forme :SolidMasse moléculaire :557.04RGB-286638 free base
CAS :RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formule :C29H35N7O4Degré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :545.63Vactosertib
CAS :Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.Formule :C22H18FN7Degré de pureté :98.85% - 99.81%Couleur et forme :SolidMasse moléculaire :399.42JI-101
CAS :JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Formule :C22H20BrN5O2Degré de pureté :99.41% - 99.97%Couleur et forme :SolidMasse moléculaire :466.33Ibuprofen Lysine
CAS :Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.Formule :C19H32N2O4Degré de pureté :99.26%Couleur et forme :CoaMasse moléculaire :352.47BIIB068
CAS :BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.Formule :C23H29N7O2Degré de pureté :97.98%Couleur et forme :SolidMasse moléculaire :435.52Ref: TM-T9192
1mg46,00€5mg90,00€10mg152,00€25mg264,00€50mg398,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)100,00€(Rac)-IBT6A
CAS :(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.Formule :C22H22N6ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :386.45Ref: TM-T10626
1mg44,00€2mg57,00€5mg93,00€10mg120,00€25mg215,00€50mg313,00€100mg439,00€200mg628,00€1mL*10mM (DMSO)92,00€2,4-DPD
CAS :2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)Formule :C11H13NO4Degré de pureté :99.74%Couleur et forme :Yellow Solid CrystallineMasse moléculaire :223.23Silymarin
CAS :Silymarin, a liver-aiding polyphenolic flavonoid, is extracted from milk thistle seeds.Formule :C25H22O10Degré de pureté :98%Couleur et forme :Yellow And Brown PowderMasse moléculaire :482.441PD153035
CAS :PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formule :C16H14BrN3O2Degré de pureté :98.47% - 99.29%Couleur et forme :SolidMasse moléculaire :360.21Crizotinib
CAS :Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.Formule :C21H22Cl2FN5ODegré de pureté :99% - 99.87%Couleur et forme :SolidMasse moléculaire :450.34Ref: TM-T1661
2mgÀ demander5mg33,00€10mg49,00€25mg55,00€50mg64,00€100mg88,00€500mg147,00€1mL*10mM (DMSO)50,00€Tucatinib
CAS :Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).Formule :C26H24N8O2Degré de pureté :99.05% - 99.96%Couleur et forme :SolidMasse moléculaire :480.52Ref: TM-T2364
1g1.071,00€2mg34,00€5mg50,00€10mg74,00€25mg117,00€50mg177,00€100mg333,00€500mg782,00€1mL*10mM (DMSO)82,00€Poziotinib
CAS :Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).Formule :C23H21Cl2FN4O3Degré de pureté :98.69% - 99.78%Couleur et forme :SolidMasse moléculaire :491.34SCR-1481B1
CAS :SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFormule :C32H40ClF2N6O13PDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :821.12Ref: TM-T5349
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg200,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)102,00€NCGC00262650
CAS :NCGC00262650 is an inhibitor of AMA1-RON2 interaction and c-Src tyrosine kinase activity.
Formule :C18H20N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :308.38PP2
CAS :PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formule :C15H16ClN5Degré de pureté :98% - 98.21%Couleur et forme :White SolidMasse moléculaire :301.77Ref: TM-T6266
2mg44,00€5mg65,00€10mg110,00€25mg178,00€50mg304,00€100mg482,00€200mg687,00€1mL*10mM (DMSO)71,00€CEP-28122 mesylate salt
CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.Formule :C29H39ClN6O6SCouleur et forme :SolidMasse moléculaire :635.17BMS-536924
CAS :BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity forFormule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96Cerdulatinib
CAS :Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formule :C20H27N7O3SDegré de pureté :98.74% - 99.49%Couleur et forme :SolidMasse moléculaire :445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€1mL*10mM (DMSO)81,00€BMS817378
CAS :BMS817378 is a potent and selective inhibitor of MET(IC50 : 1.7 nM).Formule :C24H18ClF2N4O7PDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :578.85Theliatinib tartrate
CAS :Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.Formule :C29H32N6O8Couleur et forme :SolidMasse moléculaire :592.6MCB-613
CAS :MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Formule :C20H20N2ODegré de pureté :98.17% - 99.754%Couleur et forme :SolidMasse moléculaire :304.39Ref: TM-T6886
1mg43,00€2mg56,00€5mg93,00€10mg137,00€25mg245,00€50mg358,00€100mg537,00€1mL*10mM (DMSO)90,00€(Rac)-JBJ-04-125-02
CAS :(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.Formule :C29H26FN5O3SDegré de pureté :97.57%Couleur et forme :SolidMasse moléculaire :543.61Ref: TM-T8872
1mg100,00€5mg205,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€1mL*10mM (DMSO)249,00€Onatasertib
CAS :Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formule :C21H27N5O3Degré de pureté :99.14% - 99.93%Couleur et forme :SolidMasse moléculaire :397.47TAS0728
CAS :TAS0728 is a HER2 inhibitor, with antitumor activityFormule :C26H32N8O3Degré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :504.58Ref: TM-T7819
1mg48,00€5mg105,00€10mg166,00€25mg304,00€50mg485,00€100mg658,00€200mg888,00€1mL*10mM (DMSO)111,00€WHI-P180
CAS :WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Formule :C16H15N3O3Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :297.31Blu-782
CAS :Blu-782 (ALK2-IN-1) is a activin receptor-like kinase-2 (ALK2) inhibitor ( IC50 of <10 nM)
Formule :C31H42N6O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :562.7FGFR2-IN-3 hydrochloride
CAS :FGFR2-IN-3 hydrochloride is a selective, orally active FGFR2 inhibitor.Formule :C28H25ClFN7O2Couleur et forme :SolidMasse moléculaire :546.0AZD3759 hydrochloride
CAS :AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formule :C22H24Cl2FN5O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :496.36Ref: TM-T4249
2mg34,00€5mg46,00€10mg62,00€25mg94,00€50mg167,00€100mg265,00€200mg385,00€1mL*10mM (DMSO)49,00€Tranilast
CAS :Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment ofFormule :C18H17NO5Degré de pureté :99.67% - >99.99%Couleur et forme :White With Light Yellow Crystalline PowderMasse moléculaire :327.33Ref: TM-T2690
5mg43,00€10mg55,00€25mg66,00€50mg93,00€100mg119,00€200mg175,00€500mg298,00€1mL*10mM (DMSO)55,00€PRT-060318
CAS :PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formule :C18H24N6ODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :340.42Filgotinib
CAS :Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formule :C21H23N5O3SDegré de pureté :98.03% - ≥95%Couleur et forme :SolidMasse moléculaire :425.5NRC-2694 hydrochloride
CAS :NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Formule :C24H27ClN4O3Couleur et forme :SolidMasse moléculaire :454.95SU 5402
CAS :SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formule :C17H16N2O3Degré de pureté :98.91% - 99.64%Couleur et forme :Yellow-Green SolidMasse moléculaire :296.32JK-P3
CAS :JK-P3: a pyrazole inhibitor of VEGFR-2 (IC50: 7.8 μM), stalls FGFR 1/3 in vitro, halts HUVEC wound healing/tube formation, not cell growth.Formule :C18H17N3O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :323.35JCN037
CAS :JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).Formule :C16H11BrFN3O2Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :376.18Tolimidone
CAS :Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
Formule :C11H10N2O2Degré de pureté :99.85% - 99.85%Couleur et forme :SolidMasse moléculaire :202.21TX1-85-1
CAS :TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Formule :C32H36N8O3Degré de pureté :97.16% - 98.12%Couleur et forme :SolidMasse moléculaire :580.68R-268712
CAS :R-268712 is a potent ALK5 inhibitor with a 2.5 nM IC50, also targeting TGF-β type I receptor orally.Formule :C20H18FN5ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :363.39Ref: TM-T16708
1mg44,00€5mg93,00€10mg130,00€25mg250,00€50mg378,00€100mg537,00€200mg762,00€1mL*10mM (DMSO)92,00€Vadimezan
CAS :Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity.Formule :C17H14O4Degré de pureté :97.38% - 99.8%Couleur et forme :SolidMasse moléculaire :282.29Ref: TM-T6273
2mg39,00€5mg58,00€10mg93,00€25mg172,00€50mg268,00€100mg401,00€200mg580,00€1mL*10mM (DMSO)89,00€Pelitinib
CAS :Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formule :C24H23ClFN5O2Degré de pureté :98.37% - 99.84%Couleur et forme :Off-White SolidMasse moléculaire :467.92PF 477736
CAS :PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Formule :C22H25N7O2Degré de pureté :97.58% - 99.94%Couleur et forme :SolidMasse moléculaire :419.48
