Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(167 produits)
- Bcr-Abl(118 produits)
- EGFR(581 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2386 produits trouvés pour "Angiogenèse"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Naphazoline nitrate
CAS :Naphazoline nitrate: α1-adrenergic agonist, induces autophagy, necrosis in cancer cells, inhibits differentiation, treats congestion and eye issues.Formule :C14H15N3O3Degré de pureté :98%Couleur et forme :White Crystalline Powder White SolidMasse moléculaire :273.29Sunitinib-d10
CAS :Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).Formule :C22H27FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.54BI-4142
CAS :BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.Formule :C28H27N9O2Degré de pureté :97.21% - 98.09%Couleur et forme :SolidMasse moléculaire :521.57Ref: TM-T63643
1mg57,00€5mg120,00€1mL*10mM (DMSO)138,00€10mg177,00€25mg356,00€50mg537,00€100mg803,00€200mg1.341,00€IBT6A hydrochloride
CAS :IBT6A hydrochloride: Ibrutinib impurity, Btk inhibitor IC50: 0.5 nM, used in dimer/adduct synthesis.Formule :C22H23ClN6OCouleur et forme :SolidMasse moléculaire :422.91Erlotinib-d6 hydrochloride
CAS :Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Formule :C22H24ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.93iHCK-37
CAS :iHCK-37 (ASN05260065) is an Hck inhibitor with antitumor activity and blocks HIV-1 replication, used in chronic myelogenous leukemia (CML) research.Formule :C30H32N4O2S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :544.73Ponatinib-d8
CAS :Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Formule :C29H27F3N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.61GW2974
CAS :GW2974, Oral EGFR/ErbB2 dual inhibitor, inhibits glioblastoma multiforme (GBM) cell invasion and tumor growth.Formule :C23H21N7Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :395.46(3S,4S)-PF-06459988
CAS :(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Formule :C19H22ClN7O3Couleur et forme :SolidMasse moléculaire :431.88Nilotinib-d6
CAS :Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.Formule :C28H22F3N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.55SU11652
CAS :SU11652 is an effective and competitive receptor tyrosine kinase (RTK) inhibitor, including VEGFR, FGFR, PDGFR, and Kit.Formule :C22H27ClN4O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :414.93FLT3-IN-16
CAS :FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.Formule :C15H15N3O2SDegré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :301.36Ref: TM-T9843
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg86,00€25mg172,00€50mg260,00€100mg369,00€200mg487,00€Tucatinib hemiethanolate
CAS :Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.Formule :C54H54N16O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :1007.11(E/Z)-Zotiraciclib hydrochloride
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) hydrochloride is a potent inhibitor of CDK2, JAK2, and FLT3.Formule :C23H25ClN4OCouleur et forme :SolidMasse moléculaire :408.93DTP3
CAS :DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Formule :C26H35N7O5Couleur et forme :SolidMasse moléculaire :525.6Atinvicitinib
CAS :Atinvicitinib, a selective JAK1 inhibitor, blocks cytokine signaling, modulating itch, allergy, and inflammatory responses, immune and therapeutic studies.Formule :C16H17FN6O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :360.35Ref: TM-T39646
1mg138,00€1mL*10mM (DMSO)264,00€5mg334,00€10mg550,00€25mg1.063,00€50mg1.738,00€100mg2.547,00€Flurandrenolide
CAS :Flurandrenolide is a corticosteroid with anti-inflammatory effects that activates EGFR (EC50=23 nM).Formule :C24H33FO6Couleur et forme :Crystals From Acetone + Hexane SolidMasse moléculaire :436.51LDN-193189 Tetrahydrochloride
CAS :LDN193189 is a BMPI receptor inhibitor, blocking ALK2 and ALK3 effectively, while weak on ALK4, ALK5, ALK7.Formule :C25H26Cl4N6Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :552.33Asciminib hydrochloride
CAS :Asciminib hydrochloride is a STAMP inhibitor targeting the ABL myristoyl pocket, applied in Ph+ CML research for selective oncogenic signaling modulation.Formule :C20H19Cl2F2N5O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :486.3Ref: TM-T63226
1mg57,00€5mg130,00€1mL*10mM (DMSO)138,00€10mg177,00€25mg289,00€50mg409,00€100mg620,00€CHZ868
CAS :CHZ868 is a type II JAK inhibitor with potential antitumor activity that reverses the persistence of type I JAK inhibitors and can be used to study leukemia.Formule :C22H19F2N5O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :423.42A-770041
CAS :A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Formule :C34H39N9O3Degré de pureté :99.23% - 99.86%Couleur et forme :SolidMasse moléculaire :621.73Ref: TM-T14074
2mg70,00€5mg104,00€1mL*10mM (DMSO)142,00€10mg170,00€25mg384,00€50mg652,00€100mg1.018,00€200mg1.350,00€NX-5948
CAS :NX-5948 (BTK-IN-24) is a PROTAC-type BTK degrader with anti-inflammatory and anticancer activities, inhibiting B cell activation.Formule :C42H54N12O5Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :806.96Erlotinib-d6
CAS :Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .Formule :C22H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.47Aflibercept
CAS :Aflibercept has a wide range of applications in life science related research.Couleur et forme :LiquidIlunocitinib
CAS :Ilunocitinib is a non-selective and orally active Janus kinase (JAK) inhibitor for pruritus and atopic dermatitis caused by atopic dermatitis in dogs.Formule :C17H17N7O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :383.43Ref: TM-T38571
1mg92,00€5mg230,00€1mL*10mM (DMSO)251,00€10mg356,00€25mg713,00€50mg1.189,00€100mg1.791,00€200mg2.412,00€Telatinib mesylate
CAS :Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).Formule :C21H20ClN5O6SCouleur et forme :SolidMasse moléculaire :505.93SM1-71
CAS :SM1-71 is a TAK1 inhibitor that inhibits MKNK2 and RSK2.SM1-71 acts as a kinase probe with anticancer activity.Formule :C24H26ClN7ODegré de pureté :96%Couleur et forme :SolidMasse moléculaire :463.96BPR1K871
CAS :BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values ofFormule :C25H28ClN7O2SCouleur et forme :SolidMasse moléculaire :526.05Pentagamavunon-1
CAS :PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Formule :C23H24O3Couleur et forme :SolidMasse moléculaire :348.43SM27
CAS :SM27 is a fibroblast growth factor 2 (FGF2) inhibitor with anti-angiogenic activity and can be used to study tumours.Formule :C21H16N2O9S2Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :504.49Osimertinib dimesylate
CAS :Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Formule :C30H41N7O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :691.82Lanraplenib succinate
CAS :Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formule :C58H68N18O14Couleur et forme :SolidMasse moléculaire :1241.294Cediranib maleate
CAS :Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.Formule :C29H31FN4O7Couleur et forme :SolidMasse moléculaire :566.58Mavelertinib
CAS :Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Formule :C18H22FN9O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :415.42Tetrac
CAS :Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blockingFormule :C14H8I4O4Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :747.83Neratinib maleate
CAS :Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Formule :C34H33ClN6O7Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :673.11NSC 12
CAS :NSC 12 is an orally active pan-FGF trap that binds FGF2 and interferes with its interaction with FGFR1 with potential FGF-dependent antitumor activity.Formule :C24H34F6O3Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :484.52Pazopanib-d6
CAS :Pazopanib-d6 is a deuterated compound of Pazopanib.Formule :C21H17D6N7O2SCouleur et forme :SolidMasse moléculaire :443.56Zanubrutinib-d5
Zanubrutinib-d5 (BGB-3111-d5) is a deuterium-labeled Zanubrutinib, an orally available Bruton's tyrosine kinase inhibitor for the study of B-cell malignancies.Formule :C27H29N5O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :476.58Surfen dihydrochloride
CAS :Surfen dihydrochloride (Aminoquinuride dihydrochloride) is a heparin sulfate antagonist with antimicrobial properties and inhibits blockade of signaling.Formule :C21H22Cl2N6ODegré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :445.35Bleximenib oxalate
CAS :Bleximenib oxalate (Menin-MLL inhibitor 24 oxalate) is a menin-MLL inhibitor that blocks the binding of the menin-KMT2A complex to chromatin at gene promoters.Formule :C34H52FN7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :689.82(Z)-Orantinib
CAS :(Z)-Orantinib ((Z)-SU6668) is an orally active ATP-competitive inhibitor of Flk-1/KDR, PDGFRβ, and FGFR1, acting as a potent anti-angiogenic and anti-tumor agent.Formule :C18H18N2O3Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :310.35Brivanib
CAS :Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFormule :C19H19FN4O3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :370.38Ref: TM-T6036
1mg44,00€1mL*10mM (DMSO)92,00€5mg94,00€10mg137,00€25mg245,00€50mg355,00€100mg530,00€200mg772,00€Regorafenib-d3
CAS :Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.Formule :C21H15ClF4N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.83SB1317
CAS :SB1317 (TG02) is a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).Formule :C23H24N4ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :372.46Ribociclib-d6
CAS :Ribociclib-d6 is a deuterated compound of Ribociclib (LEE011) for isotope tracing.Ribociclib is an orally available CDK4/6 inhibitor with antitumor activity.Formule :C23H30N8OCouleur et forme :SolidMasse moléculaire :440.57Lck inhibitor 2
CAS :Lck inhibitor 2 blocks tyrosine kinases LCK, BTK, LYN, SYK, TXK with IC50s: Lck 13nM, Btk 9nM/26nM, Lyn 3nM, Txk 2nM.Formule :C18H17N5O2Couleur et forme :SolidMasse moléculaire :335.36N-piperidine Ibrutinib hydrochloride
CAS :N-piperidine Ibrutinib hydrochloride is a BTK inhibitor that inhibits WT BTK and C481S BTK , which inhibits the growth and proliferation of cancer cells.Formule :C22H23ClN6ODegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :422.91Iruplinalkib
CAS :Iruplinalkib (WX-0593) is an orally active, selective and potent ALK and ROS1 tyrosine kinase inhibitor with anticancer activity for use in the study of non-small cell lung cancer.Formule :C29H38ClN6O2PDegré de pureté :97.38% - 99.29%Couleur et forme :SolidMasse moléculaire :569.08Poseltinib
CAS :Poseltinib is an oral, irreversible BTK inhibitor (IC50 1.95 nM) with higher selectivity over BMX, TEC, and TXK, blocking BCR, FcR, and TLR signaling.Formule :C26H26N6O3Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :470.52Ref: TM-T4413
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg75,00€25mg146,00€50mg260,00€100mg409,00€200mg590,00€
