Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(167 produits)
- Bcr-Abl(118 produits)
- EGFR(581 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(57 produits)
- VDA(2 produits)
- VEGFR(242 produits)
Affichez 6 plus de sous-catégories
2387 produits trouvés pour "Angiogenèse"
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ONO-4059 analog
CAS :ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formule :C25H24N6O3Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :456.5Ref: TM-T6921
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg264,00€50mg439,00€100mg627,00€Pamufetinib mesylate
CAS :Pamufetinib mesylate (TAS-115 mesylate) is a VEGFR antagonist and c-Met inhibitor used in the study of cancer and respiratory diseases.Formule :C28H27FN4O7S2Degré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :614.67MTX-211
CAS :MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formule :C20H14Cl2FN5O2SDegré de pureté :97.6% - >99.99%Couleur et forme :SolidMasse moléculaire :478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€1mL*10mM (DMSO)170,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€Theliatinib
CAS :Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).Formule :C25H26N6O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :442.51TAS6417
CAS :Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€CA-4948
CAS :CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formule :C24H25N7O5Degré de pureté :99.35% - 99.88%Couleur et forme :SolidMasse moléculaire :491.5Ref: TM-T9027
1mg34,00€2mg49,00€5mg73,00€1mL*10mM (DMSO)79,00€10mg93,00€25mg166,00€50mg295,00€100mg507,00€(E/Z)-Zotiraciclib
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46Ref: TM-T21503
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg113,00€25mg200,00€50mg330,00€100mg480,00€lavendustin C
CAS :lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26Ref: TM-T4185
1mg42,00€2mg55,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€SU 5402
CAS :SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formule :C17H16N2O3Degré de pureté :98.91% - 99.64%Couleur et forme :Yellow-Green SolidMasse moléculaire :296.32PD173074
CAS :PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formule :C28H41N7O3Degré de pureté :98.15% - 98.21%Couleur et forme :Yellow SolidMasse moléculaire :523.67Ref: TM-T2642
5mg40,00€10mg54,00€1mL*10mM (DMSO)56,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€CP-673451
CAS :CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFormule :C24H27N5O2Degré de pureté :99.62% - 99.88%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T6091
1mg49,00€2mg63,00€5mg90,00€1mL*10mM (DMSO)108,00€10mg170,00€25mg334,00€50mg512,00€100mg737,00€500mg1.521,00€Ibrutinib deacryloylpiperidine
CAS :Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.Formule :C17H13N5ODegré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :303.32(S)-Sunvozertinib
CAS :(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Formule :C29H35ClFN7O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :584.08AZD4547
CAS :AZD4547 is an FGFR family inhibitor, and is able to act on FGFR1, FGFR2, FGFR3 and FGFR4. IC50:165 nM).Cost-effective and quality-assured.Formule :C26H33N5O3Degré de pureté :99.37% - 99.88%Couleur et forme :SolidMasse moléculaire :463.57Ref: TM-T1948
2mg37,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg59,00€25mg84,00€50mg107,00€100mg147,00€200mg207,00€500mg348,00€EHop-016
CAS :EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formule :C25H30N6ODegré de pureté :98.99% - >99.99%Couleur et forme :SolidMasse moléculaire :430.55Ref: TM-T2427
5mg46,00€1mL*10mM (DMSO)49,00€10mg70,00€25mg120,00€50mg202,00€100mg316,00€200mg467,00€500mg747,00€AZD-3463
CAS :AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95ODM-203
CAS :ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormule :C26H21F2N5O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :505.54Saracatinib
CAS :Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03Cevidoplenib dimesylate hydrochloride
CAS :Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.Formule :C90H132Cl5N27O12Degré de pureté :97.52%Couleur et forme :SolidMasse moléculaire :1957.9(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.Formule :C29H32N4O8Couleur et forme :SolidMasse moléculaire :564.59ALK-IN-1
CAS :ALK-IN-1 is a potent ALK inhibitor, demonstrating the ability to overcome Crizotinib resistance mediated by an L1196M mutation.Formule :C26H34ClN6O2PDegré de pureté :99.74% - 99.80%Couleur et forme :SolidMasse moléculaire :529.01MELK-8a
CAS :MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).Formule :C25H32N6OCouleur et forme :SolidMasse moléculaire :432.56Brigatinib
CAS :Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
Formule :C29H39ClN7O2PDegré de pureté :97.18% - >99.99%Couleur et forme :SolidMasse moléculaire :584.09Ponatinib
CAS :Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormule :C29H27F3N6ODegré de pureté :98% - 99.60%Couleur et forme :SolidMasse moléculaire :532.56XL228
CAS :XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formule :C22H31N9ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :437.54Ref: TM-T17267
1mg52,00€2mg73,00€5mg94,00€1mL*10mM (DMSO)104,00€10mg141,00€25mg244,00€50mg371,00€100mg552,00€NVP-AEW541
CAS :NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormule :C27H29N5ODegré de pureté :98.7% - 99.86%Couleur et forme :SolidMasse moléculaire :439.554SC-203
CAS :4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formule :C33H38N8O4SDegré de pureté :99.52% - 99.84%Couleur et forme :SolidMasse moléculaire :642.77Tranilast
CAS :Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment ofFormule :C18H17NO5Degré de pureté :99.67% - >99.99%Couleur et forme :White With Light Yellow Crystalline PowderMasse moléculaire :327.33Ref: TM-T2690
5mg43,00€10mg55,00€1mL*10mM (DMSO)55,00€25mg66,00€50mg93,00€100mg119,00€200mg175,00€500mg298,00€(S)-Afatinib
CAS :(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.Formule :C24H25ClFN5O3Degré de pureté :99.22% - >99.99%Couleur et forme :Off-White SolidMasse moléculaire :485.94PP2
CAS :PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formule :C15H16ClN5Degré de pureté :98% - 98.21%Couleur et forme :White SolidMasse moléculaire :301.77Ref: TM-T6266
2mg44,00€5mg65,00€1mL*10mM (DMSO)71,00€10mg110,00€25mg178,00€50mg304,00€100mg482,00€200mg687,00€AEE788
CAS :AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Formule :C27H32N6Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :440.58Ref: TM-T2116
2mg47,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg103,00€25mg188,00€50mg325,00€100mg490,00€500mg1.103,00€NVP-BHG712
CAS :NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFormule :C26H20F3N7ODegré de pureté :97.32% - 98.63%Couleur et forme :SolidMasse moléculaire :503.48Ref: TM-T6348
1mg34,00€5mg74,00€1mL*10mM (DMSO)84,00€10mg105,00€25mg200,00€50mg371,00€100mg557,00€200mg790,00€A-443654
CAS :A-443654 is a pan-Akt inhibitor. A-443654 has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM).Formule :C24H23N5ODegré de pureté :98.04% - 99.51%Couleur et forme :SolidMasse moléculaire :397.47Ref: TM-T14072
1mg87,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg289,00€25mg537,00€50mg822,00€100mg1.234,00€200mg1.665,00€500mg2.457,00€SAR131675
CAS :SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Formule :C18H22N4O4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :358.39Ref: TM-T6012
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)79,00€10mg105,00€25mg215,00€50mg304,00€100mg427,00€200mg587,00€Tirbanibulin
CAS :Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53Ref: TM-T6345
1mg34,00€5mg60,00€1mL*10mM (DMSO)63,00€10mg73,00€25mg142,00€50mg253,00€100mg424,00€200mg605,00€AST 487
CAS :AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Formule :C26H30F3N7O2Degré de pureté :98.17% - 99.56%Couleur et forme :SolidMasse moléculaire :529.56Ref: TM-T4053
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)87,00€10mg113,00€25mg177,00€50mg334,00€100mg500,00€500mg1.099,00€PF-562271 besylate
CAS :PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.Formule :C21H20F3N7O3S·C6H6O3SDegré de pureté :97.65% - 99.01%Couleur et forme :SolidMasse moléculaire :665.66Ref: TM-T6177
1mg35,00€5mg74,00€1mL*10mM (DMSO)89,00€10mg94,00€25mg138,00€50mg198,00€100mg296,00€200mg427,00€FIIN-3
CAS :FIIN-3 is an irreversible inhibitor of FGFR.Formule :C34H36Cl2N8O4Degré de pureté :97.63% - 98.92%Couleur et forme :SolidMasse moléculaire :691.61CZC-8004
CAS :CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34Cediranib
CAS :Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Formule :C25H27FN4O3Degré de pureté :97.21% - 99.94%Couleur et forme :SolidMasse moléculaire :450.51Ref: TM-T2500
2mg39,00€5mg59,00€1mL*10mM (DMSO)65,00€10mg87,00€25mg129,00€50mg168,00€100mg240,00€200mg439,00€500mg703,00€Lazertinib
CAS :Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formule :C30H34N8O3Degré de pureté :98.7% - 99.90%Couleur et forme :SolidMasse moléculaire :554.64Ref: TM-T4485
1mg46,00€2mg59,00€5mg96,00€1mL*10mM (DMSO)104,00€10mg130,00€25mg215,00€50mg309,00€100mg444,00€200mg655,00€Merestinib
CAS :Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity.Formule :C30H22F2N6O3Degré de pureté :95% - 99.71%Couleur et forme :SolidMasse moléculaire :552.53Ref: TM-T3455
1mg50,00€2mg66,00€5mg100,00€1mL*10mM (DMSO)119,00€10mg137,00€25mg240,00€50mg403,00€100mg573,00€500mg1.198,00€AC1NS4RE
CAS :It is a tyrosine kinase inhibitor.Formule :C15H13ClN2ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :272.735-phenylthieno[2,3-d]pyrimidin-4-amine
CAS :5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formule :C12H9N3SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :227.29Ref: TM-T50042
2mg43,00€5mg60,00€1mL*10mM (DMSO)60,00€10mg90,00€25mg138,00€50mg200,00€100mg301,00€200mg432,00€UNC0064-12 hydrochloride (1430089-64-7(free base))
UNC0064-12 hydrochloride is an inhibitor of VEGFR2.Formule :C19H25ClN8Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :400.91Ref: TM-T2056L
1mg84,00€5mg168,00€1mL*10mM (DMSO)185,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€Arnebin 1
CAS :(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.Formule :C21H22O6Degré de pureté :98.76% - 99.81%Couleur et forme :SolidMasse moléculaire :370.40Ref: TM-T4586
1mg34,00€5mg67,00€1mL*10mM (DMSO)74,00€10mg96,00€25mg138,00€50mg200,00€100mg294,00€200mg437,00€Merestinib dihydrochloride
CAS :Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.Formule :C30H24Cl2F2N6O3Couleur et forme :SolidMasse moléculaire :625.45PD153035
CAS :PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formule :C16H14BrN3O2Degré de pureté :98.47% - 99.29%Couleur et forme :SolidMasse moléculaire :360.21Syk Inhibitor II dihydrochloride
CAS :Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formule :C14H17Cl2F3N6ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :413.22Ref: TM-T4391
1mg130,00€2mg212,00€5mg455,00€1mL*10mM (DMSO)455,00€10mg647,00€25mg947,00€50mg1.264,00€100mg1.700,00€GluR6 antagonist-1
CAS :GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.Formule :C15H11ClN2OSDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :302.78
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