Angiogenèse
Les inhibiteurs de l'angiogenèse sont des composés qui interfèrent avec la formation de nouveaux vaisseaux sanguins, un processus crucial dans la croissance et la métastase des cancers. En inhibant l'angiogenèse, ces composés peuvent restreindre l'apport sanguin aux tumeurs, ralentissant ou arrêtant leur croissance. Les inhibiteurs de l'angiogenèse sont essentiels dans la recherche sur le cancer et le développement thérapeutique, offrant des informations sur les mécanismes de progression tumorale et proposant des traitements potentiels pour le cancer et d'autres maladies liées à l'angiogenèse. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de l'angiogenèse de haute qualité pour soutenir vos recherches en oncologie et biologie vasculaire.
Sous-catégories appartenant à la catégorie "Angiogenèse"
- BTK(167 produits)
- Bcr-Abl(118 produits)
- EGFR(587 produits)
- FAK(72 produits)
- FLT(86 produits)
- Récepteur du facteur de croissance des fibroblastes (FGFR)(180 produits)
- JAK(243 produits)
- PDGFR(129 produits)
- RAAS(89 produits)
- Src(82 produits)
- Syk(37 produits)
- Thrombine(58 produits)
- VDA(2 produits)
- VEGFR(244 produits)
Affichez 6 plus de sous-catégories
2400 produits trouvés pour "Angiogenèse"
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CZC-8004
CAS :CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34KI8751
CAS :KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Formule :C24H18F3N3O4Degré de pureté :99.22% - 99.9%Couleur et forme :SolidMasse moléculaire :469.41Ref: TM-T2446
2mg34,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg81,00€25mg147,00€50mg279,00€100mg447,00€200mg635,00€Sitravatinib
CAS :Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormule :C33H29F2N5O4SDegré de pureté :98.9% - 99.85%Couleur et forme :SolidMasse moléculaire :629.68Ref: TM-T4349
5mg49,00€1mL*10mM (DMSO)69,00€10mg74,00€25mg130,00€50mg200,00€100mg319,00€200mg507,00€500mg800,00€R112
CAS :R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formule :C16H13FN4O2Degré de pureté :99.27% - 99.84%Couleur et forme :SolidMasse moléculaire :312.3Ref: TM-T3185
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg311,00€100mg462,00€500mg973,00€AC1NS4RE
CAS :It is a tyrosine kinase inhibitor.Formule :C15H13ClN2ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :272.73CL-387785
CAS :CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Formule :C18H13BrN4ODegré de pureté :99.56% - 99.62%Couleur et forme :SolidMasse moléculaire :381.235-phenylthieno[2,3-d]pyrimidin-4-amine
CAS :5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formule :C12H9N3SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :227.29Ref: TM-T50042
2mg43,00€5mg60,00€1mL*10mM (DMSO)60,00€10mg90,00€25mg138,00€50mg200,00€100mg301,00€200mg432,00€BMS-2
CAS :BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Formule :C25H16F2N4O3Degré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :458.42Ref: TM-T8326
1mg67,00€2mg88,00€5mg148,00€1mL*10mM (DMSO)170,00€10mg230,00€25mg430,00€50mg622,00€100mg898,00€Arnebin 1
CAS :(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.Formule :C21H22O6Degré de pureté :98.76% - 99.81%Couleur et forme :SolidMasse moléculaire :370.40Ref: TM-T4586
1mg34,00€5mg67,00€1mL*10mM (DMSO)74,00€10mg96,00€25mg138,00€50mg200,00€100mg294,00€200mg437,00€Merestinib dihydrochloride
CAS :Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.Formule :C30H24Cl2F2N6O3Couleur et forme :SolidMasse moléculaire :625.45Tyrphostin B44, (+) enantiomer
CAS :Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Formule :C18H16N2O3Degré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :308.33Ref: TM-T22450
1mg39,00€5mg82,00€1mL*10mM (DMSO)90,00€10mg115,00€25mg192,00€50mg264,00€100mg380,00€200mg515,00€URMC-099
CAS :URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formule :C27H27N5Degré de pureté :99.32% - 99.98%Couleur et forme :SolidMasse moléculaire :421.54VEGFR-2-IN-5
CAS :VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formule :C19H24N8Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :364.45Ref: TM-T2056
1mg90,00€5mg222,00€1mL*10mM (DMSO)224,00€10mg333,00€25mg560,00€50mg797,00€100mg1.071,00€Syk Inhibitor II dihydrochloride
CAS :Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formule :C14H17Cl2F3N6ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :413.22Ref: TM-T4391
1mg130,00€2mg212,00€5mg455,00€1mL*10mM (DMSO)455,00€10mg647,00€25mg947,00€50mg1.264,00€100mg1.700,00€GluR6 antagonist-1
CAS :GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.Formule :C15H11ClN2OSDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :302.78TAK-632
CAS :TAK-632 is a potent pan-Raf inhibitor.Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52Fisogatinib
CAS :Fisogatinib (BLU-554) is a highly potent, selective, and orally active FGFR4 inhibitor.Cost-effective and quality-assured.Formule :C24H24Cl2N4O4Degré de pureté :99.27% - ≥95%Couleur et forme :SolidMasse moléculaire :503.38Ref: TM-T3456
1mg50,00€5mg114,00€1mL*10mM (DMSO)127,00€10mg167,00€25mg294,00€50mg444,00€100mg670,00€500mg1.341,00€ONO-4059 analog
CAS :ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formule :C25H24N6O3Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :456.5Ref: TM-T6921
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg264,00€50mg439,00€100mg627,00€Acalabrutinib
CAS :Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Formule :C26H23N7O2Degré de pureté :98.94% - 99.64%Couleur et forme :SolidMasse moléculaire :465.51Ref: TM-T3626
5mg44,00€1mL*10mM (DMSO)48,00€10mg57,00€25mg78,00€50mg90,00€100mg144,00€200mg215,00€500mg355,00€PP121
CAS :PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formule :C17H17N7Degré de pureté :98.45% - 99.93%Couleur et forme :SolidMasse moléculaire :319.361-Naphthyl PP1
CAS :1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Formule :C19H19N5Degré de pureté :99.85%Couleur et forme :White Cyrstalline SolidMasse moléculaire :317.39Masitinib
CAS :Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formule :C28H30N6OSDegré de pureté :97.56% - >99.99%Couleur et forme :SolidMasse moléculaire :498.64LDN-212854
CAS :LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Formule :C25H22N6Degré de pureté :98% - 98.71%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T1900
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)102,00€10mg172,00€25mg294,00€50mg439,00€100mg660,00€200mg945,00€Gefitinib dihydrochloride
CAS :Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.Formule :C22H26Cl3FN4O3Couleur et forme :SolidMasse moléculaire :519.82MTX-211
CAS :MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formule :C20H14Cl2FN5O2SDegré de pureté :97.6% - >99.99%Couleur et forme :SolidMasse moléculaire :478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€1mL*10mM (DMSO)170,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€Tivozanib
CAS :Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formule :C22H19ClN4O5Degré de pureté :98.08% - 99.67%Couleur et forme :SolidMasse moléculaire :454.86Ref: TM-T2456
2mg38,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg79,00€25mg135,00€50mg226,00€100mg405,00€200mg597,00€SUN11602
CAS :SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Formule :C26H37N5O2Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :451.6TAS6417
CAS :Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€(E/Z)-Zotiraciclib
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46Ref: TM-T21503
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg113,00€25mg200,00€50mg330,00€100mg480,00€SU 5402
CAS :SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formule :C17H16N2O3Degré de pureté :98.91% - 99.64%Couleur et forme :Yellow-Green SolidMasse moléculaire :296.32Quizartinib HCl
CAS :Quizartinib (AC220/AC010220) is an oral FLT3/STK1 inhibitor for treating AML, blocking kinase-driven cell proliferation and promoting apoptosis.Formule :C29H34Cl2N6O4SCouleur et forme :SolidMasse moléculaire :633.59Adaphostin
CAS :Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Formule :C24H27NO4Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :393.487BIO
CAS :7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formule :C16H10BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :356.17GSK1838705A
CAS :GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formule :C27H29FN8O3Degré de pureté :98.89% - >99.99%Couleur et forme :SolidMasse moléculaire :532.571-Naphthyl PP1 hydrochloride
CAS :1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormule :C19H20ClN5Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :353.85Momelotinib HCl
CAS :Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formule :C23H24Cl2N6O2Couleur et forme :SolidMasse moléculaire :487.38(E)-AG 99
CAS :(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).Formule :C10H8N2O3Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :204.185'-Fluoroindirubinoxime
CAS :5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).Formule :C16H10FN3O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :295.27Olverembatinib dimesylate
CAS :Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Formule :C29H27F3N6O·2CH4O3SDegré de pureté :97.66% - >99.99%Couleur et forme :SolidMasse moléculaire :724.77Ref: TM-T2429
1mg37,00€5mg79,00€10mg113,00€1mL*10mM (DMSO)114,00€25mg216,00€50mg289,00€100mg378,00€200mg552,00€lavendustin C
CAS :lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26Ref: TM-T4185
1mg42,00€2mg55,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€Dovitinib lactate hydrate
CAS :Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51Ruxolitinib phosphate
CAS :Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formule :C17H21N6O4PDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :404.36Ref: TM-T3043
5mg49,00€1mL*10mM (DMSO)56,00€10mg62,00€25mg78,00€50mg92,00€100mg138,00€200mg215,00€500mg395,00€1g583,00€Saracatinib
CAS :Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formule :C27H32ClN5O5Degré de pureté :98% - 99.63%Couleur et forme :SolidMasse moléculaire :542.03AZD-3463
CAS :AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95SB-431542
CAS :SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.Formule :C22H16N4O3Degré de pureté :99.035% - >99.99%Couleur et forme :SolidMasse moléculaire :384.39GDC-0214
CAS :GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formule :C28H28ClF2N9O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :612.03Ref: TM-T9826
1mg93,00€5mg182,00€1mL*10mM (DMSO)245,00€10mg269,00€25mg429,00€50mg610,00€100mg820,00€200mg1.099,00€Tyrphostin A1
CAS :Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formule :C11H8N2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :184.19ODM-203
CAS :ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormule :C26H21F2N5O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :505.54PD-161570
CAS :PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formule :C26H35Cl2N7ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :532.51Ref: TM-T23127
1mg34,00€5mg96,00€1mL*10mM (DMSO)118,00€10mg141,00€25mg289,00€50mg465,00€100mg662,00€200mg888,00€Tranilast
CAS :Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment ofFormule :C18H17NO5Degré de pureté :99.67% - >99.99%Couleur et forme :White With Light Yellow Crystalline PowderMasse moléculaire :327.33Ref: TM-T2690
5mg43,00€10mg55,00€1mL*10mM (DMSO)55,00€25mg66,00€50mg93,00€100mg119,00€200mg175,00€500mg298,00€
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