Thrombine
Les inhibiteurs de la thrombine sont des composés qui bloquent la thrombine, une enzyme impliquée dans le processus de coagulation sanguine, qui joue également un rôle dans la promotion de l'angiogenèse. La thrombine peut stimuler la formation de nouveaux vaisseaux sanguins dans les tumeurs, favorisant ainsi leur croissance et leurs métastases. En inhibant la thrombine, ces composés peuvent réduire l'angiogenèse et la progression tumorale. Les inhibiteurs de la thrombine sont importants à la fois dans la recherche sur le cancer et dans l'étude des maladies vasculaires. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de la thrombine de haute qualité pour soutenir vos recherches en hémostase, oncologie et angiogenèse.
51 produits trouvés pour "Thrombine"
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Dabigatran ethyl ester hydrochloride
CAS :Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Formule :C27H30ClN7O3Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :536.03Dabigatran etexilate
CAS :Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Formule :C34H41N7O5Degré de pureté :98.19% - 99.98%Couleur et forme :White PowderMasse moléculaire :627.73Thrombin inhibitor 13
Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.Formule :C16H17ClN6OSCouleur et forme :SolidMasse moléculaire :376.864Acetyl-Hirudin (54-65) (sulfated)
CAS :Acetyl-Hirudin (54-65) (sulfated) binds thrombin-rHCII(L444R), blocking rHCII's N-terminal/thrombin exosite I interaction, stabilizing the complex.Formule :C68H95N13O29SCouleur et forme :SolidMasse moléculaire :1590.63Fibrinopeptide B, human
CAS :Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.Formule :C66H93N19O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1552.56Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Couleur et forme :Odour SolidRef: TM-L1100
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderThrombin (MW 37kDa)
CAS :Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :37kDaSulodexide
CAS :Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Couleur et forme :SolidHirudin (54-65) (TFA)
Hirudin (54-65) TFA, a segment of the 65-amino-acid protein Hirudin, exhibits anticoagulant properties [1].Couleur et forme :Odour SolidKnob A peptide GPRPFPAC
CAS :Knob A peptide GPRPFPAC is a fibrin knob peptide. The PEGylated form of Knob A peptide GPRPFPAC exhibits enhanced anticoagulant activity.Formule :C38H57N11O9SCouleur et forme :SolidMasse moléculaire :843.99Fibrinogen-Binding Peptide
CAS :Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.Formule :C25H39N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :565.62PM 102
CAS :Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).Formule :C235H425N111O64Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5830Hirudin (55-65) (sulfated)
CAS :Hirudin (55-65) (sulfated), a fragment of Hirudin, is a thrombin inhibitor with anticoagulant effects and blood anticoagulant properties.Formule :C64H90N12O27SCouleur et forme :SolidMasse moléculaire :1491.53Metolazone
CAS :Metolazone (SR-720-22) is a quinazoline-sulfonamide derived diuretic that inhibits sodium chloride symporters.
Formule :C16H16ClN3O3SDegré de pureté :98.14% - 98.5%Couleur et forme :Crystals From Ethanol SolidMasse moléculaire :365.83Ichorcumab
CAS :Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Couleur et forme :LiquidH-Gly-Arg-pNA dihydrochloride
CAS :H-Gly-Arg-pNA 2HCl, a peptide, binds 1,2 thrombin; colorimetric quantification at 405 nm indicates thrombin activity.Formule :C14H23Cl2N7O4Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :424.28Platelet aggregation-IN-1
Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.Formule :C18H13N3O4Masse moléculaire :335.09061Anti-Coagulation Factor II Antibody (8M286)
Anti-Coagulation Factor II Antibody (8M286) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (8M286) can be used in ELISA.Couleur et forme :Odour LiquidAnti-Coagulation Factor II Antibody (2P591)
Anti-Coagulation Factor II Antibody (2P591) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (2P591) can be used in WB.Couleur et forme :Odour LiquidDabigatran ethyl ester
CAS :Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.Formule :C27H29N7O3Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :499.56
