Ferroptose
La ferroptose est une forme de mort cellulaire régulée caractérisée par l'accumulation de peroxydes lipidiques et par le stress oxydatif dépendant du fer. Contrairement à l'apoptose, la ferroptose n'est pas entraînée par les caspases, mais plutôt par l'échec des défenses antioxydantes cellulaires, conduisant à la mort cellulaire. Les inhibiteurs et inducteurs de la ferroptose sont essentiels pour étudier cette voie unique de mort cellulaire, impliquée dans diverses maladies, notamment le cancer, la neurodégénérescence et les lésions d'ischémie-reperfusion. Chez CymitQuimica, nous offrons une large gamme de modulateurs de la ferroptose de haute qualité pour soutenir vos recherches sur les mécanismes de mort cellulaire, le stress oxydatif et la pathologie des maladies.
215 produits trouvés pour "Ferroptose"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Simvastatin
CAS :Formule :C25H38O5Degré de pureté :>97.0%(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :418.57Erastin
CAS :Formule :C30H31ClN4O4Degré de pureté :>98.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :547.056-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
CAS :Formule :C14H18O4Degré de pureté :>98.0%(GC)(T)Couleur et forme :White to Orange to Green powder to crystalineMasse moléculaire :250.29Sulfasalazine
CAS :Formule :C18H14N4O5SDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :Light yellow to Amber to Dark green powder to crystalMasse moléculaire :398.39Ebselen
CAS :Formule :C13H9NOSeDegré de pureté :>98.0%(GC)Couleur et forme :Light orange to Yellow to Green powder to crystalMasse moléculaire :274.18Baicalein
CAS :Formule :C15H10O5Degré de pureté :>98.0%(T)Couleur et forme :Light yellow to Amber to Dark green powder to crystalMasse moléculaire :270.24Coenzyme Q9
CAS :Formule :C54H82O4Degré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Yellow to Orange powder to crystalMasse moléculaire :795.25L-Glutamic Acid
CAS :Formule :C5H9NO4Degré de pureté :>99.0%(T)Couleur et forme :White powder to crystalMasse moléculaire :147.13Ferrostatin-1
CAS :Formule :C15H22N2O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Amber to Dark purple powder to crystalMasse moléculaire :262.35Coenzyme Q10
CAS :Formule :C59H90O4Degré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Yellow to Orange powder to crystalMasse moléculaire :863.37EBSELEN
CAS :Formule :C13H9NOSeDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :274.1767Pioglitazone hydrochloride
CAS :<p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>Formule :C19H20N2O3S·HClDegré de pureté :99.64% - >99.99%Couleur et forme :White Crystals Or Crystalline PowderMasse moléculaire :392.90Zileuton
CAS :<p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>Formule :C11H12N2O2SDegré de pureté :98.72% - 99.43%Couleur et forme :Crystalline SolidMasse moléculaire :236.29iFSP1
CAS :<p>iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse</p>Formule :C20H13N5Degré de pureté :98.74% - 99.74%Couleur et forme :SolidMasse moléculaire :323.35Simvastatin
CAS :<p>Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.</p>Formule :C25H38O5Degré de pureté :98.54% - 99.13%Couleur et forme :SolidMasse moléculaire :418.57Linagliptin
CAS :<p>Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.</p>Formule :C25H28N8O2Degré de pureté :99.15% - >99.99%Couleur et forme :SolidMasse moléculaire :472.54Lovastatin
CAS :<p>Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.</p>Formule :C24H36O5Degré de pureté :99.66% - 99.92%Couleur et forme :The Substance Is A White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :404.54Eugenol
CAS :<p>Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.</p>Formule :C10H12O2Degré de pureté :98.03%Couleur et forme :Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)Masse moléculaire :164.2Pravastatin sodium
CAS :<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Formule :C23H35NaO7Degré de pureté :97.14%Couleur et forme :White Crystalline PowderMasse moléculaire :446.52Cisplatin
CAS :<p>Cisplatin (CDDP) is a DNA cross-linking agent.</p>Formule :Cl2H6N2PtDegré de pureté :97.13% - 99.63%Couleur et forme :Orange-Yellow To Deep Yellow Solid Or PowderMasse moléculaire :300.04Ciclopirox olamine
CAS :<p>Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.</p>Formule :C14H24N2O3Degré de pureté :99.16% - >99.99%Couleur et forme :White To Yellow Solid Solid Particulate/PowderMasse moléculaire :268.35NVS-ZP7-4
CAS :<p>NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).</p>Formule :C28H28FN5OSDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :501.62L-Glutamic Acid
CAS :Formule :C5H9NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :147.1293Matrine
CAS :<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formule :C15H24N2ODegré de pureté :97.16% - >99.99%Couleur et forme :SolidMasse moléculaire :248.36SULFASALAZINE
CAS :Formule :C18H14N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.3926Lapatinib ditosylate monohydrate
CAS :<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formule :C29H26ClFN4O4S·2(C7H8O3S)·H2ODegré de pureté :98% - 99.41%Couleur et forme :Colourless To Light-Yellow CrystalMasse moléculaire :943.47Baicalein, monohydrate
CAS :Formule :C15H10O5Degré de pureté :96%Couleur et forme :SolidMasse moléculaire :270.2369Gallic acid
CAS :<p>Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.</p>Formule :C7H6O5Degré de pureté :99.38% - 99.57%Couleur et forme :White Solid Solid Particulate/PowderMasse moléculaire :170.12Vildagliptin
CAS :<p>Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.</p>Formule :C17H25N3O2Degré de pureté :97.81% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :303.40Coenzyme Q10
CAS :Formule :C59H90O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :863.3435Ref: IN-DA00396N
1g24,00€5g40,00€10g57,00€1kgÀ demander25g99,00€2kgÀ demander50g141,00€5kgÀ demander100g196,00€DL-Glutamine
CAS :<p>DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.</p>Formule :C5H10N2O3Degré de pureté :99.89%Couleur et forme :White Crystalline Powder White Crystalline PowderMasse moléculaire :146.14Ethylenediaminetetraacetic acid trisodium salt
CAS :<p>Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.</p>Formule :C10H13N2Na3O8Degré de pureté :99.92% - 99.96%Couleur et forme :White CrystalsMasse moléculaire :358.19Roxadustat
CAS :<p>Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.</p>Formule :C19H16N2O5Degré de pureté :99% - 99.88%Couleur et forme :SolidMasse moléculaire :352.34Lapatinib Ditosylate
CAS :<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formule :C29H26ClFN4O4S·2C7H8O3SDegré de pureté :99.41%Couleur et forme :Yellow SolidMasse moléculaire :925.46Curcumin
CAS :<p>Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.</p>Formule :C21H20O6Degré de pureté :95% - 98.98%Couleur et forme :Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Masse moléculaire :368.3799FSEN1
CAS :<p>FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.</p>Formule :C22H22BrN5OSDegré de pureté :98.56% - 99.54%Couleur et forme :SolidMasse moléculaire :484.412-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuteriomethoxy)cyclohexa-2,5-diene-1,4-dione
CAS :Formule :C19H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.4385Sulfasalazine
CAS :<p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>Formule :C18H14N4O5SDegré de pureté :98.00% - 99.28%Couleur et forme :Minute Brownish-Yellow CrystalsMasse moléculaire :398.39Ciclopirox
CAS :<p>Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.</p>Formule :C12H17NO2Degré de pureté :97.72% - 99.78%Couleur et forme :SolidMasse moléculaire :207.27L-Glutathione reduced
CAS :<p>L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.</p>Formule :C10H17N3O6SDegré de pureté :97.37% - 99.99%Couleur et forme :SolidMasse moléculaire :307.32Sorafenib tosylate
CAS :<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Formule :C21H16ClF3N4O3·C7H8O3SDegré de pureté :99.24% - 99.94%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :637.03Butylhydroxyanisole
CAS :<p>BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.</p>Formule :C11H16O2Degré de pureté :99.54% - 99.63%Couleur et forme :White Solid WaxyMasse moléculaire :180.256-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
CAS :Formule :C14H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :250.2903Ref: IN-DA003N8E
1g30,00€5g66,00€10g114,00€1kgÀ demander25g159,00€50g284,00€100g526,00€500gÀ demander100mg21,00€250mg25,00€Ferrostatin-1 (Fer-1)
CAS :Formule :C15H22N2O2Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :262.3474(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
CAS :Formule :C25H38O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.5662Dopamine hydrochloride
CAS :<p>Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!</p>Formule :C8H12ClNO2Degré de pureté :99.47% - 99.72%Couleur et forme :SolidMasse moléculaire :189.64L-Glutamine
CAS :<p>L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present in the human body and involved in many metabolic processes. High-Quality, Low-Cost!</p>Formule :C5H10N2O3Degré de pureté :99.66% - 99.98%Couleur et forme :Solid CrystallineMasse moléculaire :146.14Baicalein
CAS :<p>Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.</p>Formule :C15H10O5Degré de pureté :97.06% - 98.48%Couleur et forme :Yellow Crystalline SolidMasse moléculaire :270.24Sorafenib
CAS :<p>Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57</p>Formule :C21H16ClF3N4O3Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :464.82Deferasirox
CAS :<p>Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.</p>Formule :C21H15N3O4Degré de pureté :98.79% - 99.4%Couleur et forme :SolidMasse moléculaire :373.36Rosiglitazone maleate
CAS :<p>Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.</p>Formule :C22H23N3O7SDegré de pureté :99.33% - 99.51%Couleur et forme :Off-White SolidMasse moléculaire :473.50Imidazole ketone erastin
CAS :<p>View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.</p>Formule :C35H35ClN6O5Degré de pureté :98.48% - 99.87%Couleur et forme :SolidMasse moléculaire :655.14Acetylcysteine
CAS :<p>Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.</p>Formule :C5H9NO3SDegré de pureté :98.01% - >99.99%Couleur et forme :Crystals From Water SolidMasse moléculaire :163.19α-Vitamin E
CAS :<p>α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.</p>Formule :C29H50O2Degré de pureté :98% - 99.89%Couleur et forme :Light Yellow LiquidMasse moléculaire :430.71Deferiprone
CAS :<p>Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.</p>Formule :C7H9NO2Degré de pureté :99.58% - ≥95%Couleur et forme :White NeedlesMasse moléculaire :139.15Fluvastatin sodium
CAS :<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Formule :C24H25FNNaO4Degré de pureté :98.54% - 99.56%Couleur et forme :Light Yellow Solid PowderMasse moléculaire :433.45Lapatinib
CAS :<p>Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.</p>Formule :C29H26ClFN4O4SDegré de pureté :99.00% - 99.81%Couleur et forme :PowderMasse moléculaire :581.06Butylated hydroxytoluene
CAS :<p>Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.</p>Formule :C15H24ODegré de pureté :99.72%Couleur et forme :Colourless Solid PowderMasse moléculaire :220.35Artesunate
CAS :<p>Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.</p>Formule :C19H28O8Degré de pureté :97.67% - 99.9%Couleur et forme :White Crystalline PowderMasse moléculaire :384.42Pioglitazone
CAS :<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Formule :C19H20N2O3SDegré de pureté :95% - 99.57%Couleur et forme :White PowderMasse moléculaire :356.44Artemisinin
CAS :<p>Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.</p>Formule :C15H22O5Degré de pureté :99.77% - 99.87%Couleur et forme :Crystalline SolidMasse moléculaire :282.33GDCNF-11
CAS :<p>GDCNF-11, an HSP90-based HIM-PROTACGPX4 degrader, facilitates the ubiquitination and degradation of GPX4 through the HSP90 chaperone complex. This reduction in endogenous GPX4 induces ferroptosis in HT-1080 cells, with a DC50 value of 0.08 μM.</p>Formule :C48H53Cl2N13O5SCouleur et forme :SolidMasse moléculaire :994.99Ferroptosis inducer-6
CAS :<p>Ferroptosisinducer 6 (6d) is an inducer of ferroptosis (ferroptosis) that exhibits potent potential for Type I/II photodynamic therapy by inducing ROS production, oxidative stress, and mitochondrial damage. Additionally, it demonstrates antitumor activity.</p>Formule :C69H78F12N12P2RuCouleur et forme :SolidMasse moléculaire :1466.44Fluorescein-diisobutyrate-6-amide
CAS :<p>Fluorescein-diisobutyrate-6-amide, a powerful inducer of ferroptosis, shows promise for cancer research applications [1].</p>Formule :C62H61ClN6O16Couleur et forme :SolidMasse moléculaire :1181.63NC-R17
<p>NC-R17, an RSL3-based noncovalent GPX4 degrader implicated in ferroptosis, demonstrates anti-tumor activity and is utilized in the design of noncovalent GPX4-</p>Formule :C53H67N7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :914.14Ferroptosis-IN-12
<p>Ferroptosis-IN-12 (Cpd-A1) is an inhibitor of ferroptosis. It effectively suppresses ferroptosis in mouse renal tubular epithelial cells (mTECs) treated with Erastin and improves renal function in dose-dependent manners in mouse models of acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP). This compound also reduces renal tubular damage and eliminates inflammation. Exhibiting good plasma stability and high distribution in renal tissues during pharmacokinetic studies in mice, Ferroptosis-IN-12 shows promising potential for research in the field of AKI.</p>Couleur et forme :Odour SolidFerroptosis inducer-4
<p>Ferroptosisinducer-4 (Compound 5) is a phospholipid-based ferroptosis inducer featuring a terminal double bond at the sn-2 position. It exhibits significant cytotoxicity towards HT-1080 cells with an IC50 value of 18 μM. The toxicity mechanism involves the generation of lipid peroxides and oxidative damage to the cell membrane induced by the terminal double bond. Ferroptosisinducer-4 can be utilized in studies pertaining to the regulation of ferroptosis.</p>Formule :C33H64NO7PCouleur et forme :SolidMasse moléculaire :617.84GPX4-IN-7
<p>GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.</p>Formule :C25H23ClN4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.93Ru-Poma
<p>Ru-Poma is an Ru(II)-based photosensitizer designed to enhance the efficacy of photodynamic therapy (PDT) against tumors resistant to Cisplatin. It targets Pomalidomide to partially degrade CRBN, inducing ferroptosis by increasing lipid peroxides and downregulating GPX4 and GAPDH expression. In A549 cells, Ru-Poma exhibits cytotoxicity with IC50 values of 18.46 μM in the dark and 0.37 μM under illumination.</p>Formule :C89H75Cl2N11O11Ru·7H2OPROTAC GPX4 degrader-2
<p>PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.</p>Formule :C50H61ClN8O9Masse moléculaire :952.425Anticancer agent 178
<p>Anticanceragent 178 (compound C2) is a potent anticancer compound. It effectively inhibits the proliferation and metabolic activity of MDA-MB 231 cells, with IC50 values of 1.1 and 4.2 μM, respectively. Additionally, Anticanceragent 178 induces ferroptosis and necroptosis in cells.</p>Formule :C32H30ClFeN2O6Masse moléculaire :629.11418Photosensitizer-5
<p>Photosensitizer-5, a photodynamic agent, exhibits cytotoxicity towards HeLa and HepG2 cells, with IC50 values of 10.4 nM and 6.9 nM, respectively. It induces cell death through lipid peroxidation via an iron-independent ferroptosis pathway. Additionally, Photosensitizer-5 displays antitumor activity in HeLa-tumor-bearing mice.</p>Formule :C35H26BF2IN4O2Couleur et forme :SolidMasse moléculaire :710.32NA-Ir
CAS :<p>NA-Ir is a ferroptosis (Ferroptosis) inducer that targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to stimulate ferritin autophagy (). It also induces the production of reactive oxygen species (ROS) through photodynamic therapy (PDT), depletes glutathione (GSH), and downregulates glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and ferroptosis. NA-Ir exhibits enhanced anticancer activity under light exposure and selectively inhibits cancer cells with high H2S content.</p>Formule :C49H36F6IrN8O4PCouleur et forme :SolidMasse moléculaire :1138.04Pro-GA
CAS :<p>Pro-GA is a cell-permeable γ-glutamylcyclotransferase (γ-GGCT) inhibitor that inhibit proliferation in multiple bladder cancer cell lines. antitumour.</p>Formule :C12H19NO7Couleur et forme :SolidMasse moléculaire :289.28PROTAC NCOA4 degrader-1
<p>PROTACNCOA4 degrader-1 (Compound V3) is a PROTAC-based degrader of NCOA4, exhibiting a DC50 of 3 nM in HeLa cells. Besides acting as a ferroptosis inhibitor, this compound effectively reduces the levels of NCOA4 and decreases intracellular ferrous (Fe2+) levels. Moreover, PROTACNCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model.</p>Couleur et forme :Odour SolidZX782
<p>ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.</p>Formule :C39H48ClN5O8Couleur et forme :SolidMasse moléculaire :750.28Ferroptosis Compound Library
<p>A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；</p>Couleur et forme :Odour SolidFerroptosis-IN-13
<p>Ferroptosis-IN-13 (compound NY-26) is an inhibitor of ferroptosis. It effectively suppresses RSL3-induced ferroptosis in 786-O cells, with an EC50 value of 62 nM.</p>Formule :C32H30F2N4O3Couleur et forme :SolidMasse moléculaire :556.602GPX4-IN-6
CAS :<p>GPX4-IN-6 is a GPX4 inhibitor with antitumor activity.GPX4-IN-6 induces iron death and is used for the treatment and prevention of triple-negative breast cancer</p>Formule :C18H17BrFNO5Degré de pureté :99.54%Couleur et forme :SoildMasse moléculaire :426.23Moracin N
CAS :<p>Moracin N, a ferroptosis inhibitor derived from mulberry leaves, exhibits neuroprotective activity by mitigating oxidative stress [1].</p>Formule :C19H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.34Ferroptosis-IN-1
<p>Ferroptosis-IN-1, a diterpene derived from A.</p>Formule :C22H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.51-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
CAS :<p>Phospholipid with stearic acid and 15(S)-HpETE boosts ferroptosis in MEFs upon GPX4 inhibition.</p>Formule :C43H78NO10PCouleur et forme :SolidMasse moléculaire :800.068Ferroptosis-IN-3
<p>Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).</p>Degré de pureté :98%Couleur et forme :Odour SolidVK-28
CAS :<p>VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.</p>Formule :C16H21N3O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :287.36Ferroptosis-IN-14
<p>Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.</p>Couleur et forme :Odour SolidDTUN
<p>DTUN: lipophilic radical initiator, starts STY-BODIPY liposome co-autoxidization at 0.2 mM, useful in FENIX assays.</p>Couleur et forme :Solid2-Acetamidophenol
CAS :<p>2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).</p>Formule :C8H9NO2Degré de pureté :>99.99%Couleur et forme :Light Brown PowderMasse moléculaire :151.16TOFA-Plasmalogen
<p>TOFA-Plasmalogen (compound 1), a derivative of glyceraldehyde, exhibits ferroptosis-inducing properties. This compound promotes lipid peroxidation in cell membranes, leading to cytotoxic effects with an inhibition concentration (IC 50 = 32.87 μM).</p>Formule :C33H62NO7PCouleur et forme :SolidMasse moléculaire :615.82GPX4-IN-14
<p>GPX4-IN-14 (compound 2c) acts as a GPX4 inhibitor, exhibiting both free radical scavenging activity (with a maximum scavenging rate of 72.52%) and anti-tumor proliferation activity in vitro. This compound targets GPX4 protein, elevating lipid peroxide and intracellular Reactive Oxygen Species (ROS) levels, which induces ferroptosis and contributes to its anti-tumor proliferation effects.</p>Formule :C26H39NO8SeCouleur et forme :SolidMasse moléculaire :572.55PROTAC GPX4 degrader-1
CAS :<p>PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080</p>Formule :C50H57ClN10O10Couleur et forme :SolidMasse moléculaire :993.5HDAC-IN-77
<p>HDAC-IN-77 (HL-5s), an HDAC inhibitor, has the capability to induce ferroptosis and suppress the Nrf2/HO-1 signaling pathway. This compound is utilized in cancer research.</p>Formule :C22H26N4O2SCouleur et forme :SolidMasse moléculaire :410.53VEGFR-2-IN-68
<p>VEGFR-2-IN-68 (13b) is an inhibitor of VEGFR-2 with an IC50 value of 41.51 nM. It can induce apoptosis and cause G2/M cell cycle arrest, as well as exhibit anti-cancer metastasis properties.</p>Formule :C27H25N5O2SCouleur et forme :SolidMasse moléculaire :483.1729Ferroptosis-IN-17
<p>Ferroptosis-IN-17 (Compound 18) is an inhibitor of ferroptosis with an EC50 value of 0.57 μM. It effectively reduces the accumulation of intracellular ferrous ions and lipid peroxidation while restoring levels of glutathione (GSH) and glutathione peroxidase 4 (GPX4). In rat plasma, Ferroptosis-IN-17 demonstrates good solubility and notable metabolic stability. This compound holds potential for research in tumor suppression, neurodegenerative diseases, and cardiovascular disorders.</p>Formule :C21H26N4O5SCouleur et forme :SolidMasse moléculaire :446.52Ferumoxytol
CAS :<p>Ferumoxytol is an iron oxide nanoparticle with anti-leukemia properties, specifically against acute myeloid leukemia (AML) cells with low ferroportin (FPN) expression. By increasing intracellular iron levels, Ferumoxytol induces the Fenton reaction to produce reactive oxygen species (ROS), resulting in oxidative stress and ferroptosis. It selectively kills leukemia cells with low FPN expression while sparing normal cells, making it useful for studying leukemia targeting iron metabolism abnormalities.</p>Couleur et forme :SolidCQ-ER
<p>CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).</p>Formule :C33H33N7O6SCouleur et forme :SolidMasse moléculaire :655.72Chalcones A-N-5
CAS :<p>Chalcones A-N-5, a non-cytotoxic trihydroxy chalcone, aids cell growth & neuroprotection, inhibits ferroptosis, and targets AD research.</p>Formule :C21H20N4O4Couleur et forme :SolidMasse moléculaire :392.41UAMC-4821
<p>UAMC-4821 is a ferroptosis inhibitor with an IC50 of 5.2 nM. It effectively scavenges free radicals, inhibits lipid peroxidation, and prevents ML162-induced ferroptosis, providing protective effects on HT-1080 cells. With favorable pharmacokinetic properties in mice, UAMC-4821 presents an oral bioavailability of 63% and demonstrates blood-brain barrier permeability.</p>Formule :C15H19N3OCouleur et forme :SolidMasse moléculaire :257.33PROTAC GPX4 degrader-4
CAS :<p>PROTACGPX4 degrader-4 is a GPX4 PROTAC degrader with a DC50 of 5.32 nM. It inhibits the activity of cancer cell lines RT4, T24, and J82 with IC50 values of 0.09, 2.97, and 7.58 μM, respectively. This compound elevates lipid ROS levels and induces ferroptosis in T24 and RT4 cells. In T24 tumor-bearing BALB/c nude mouse models, PROTACGPX4 degrader-4 demonstrates antitumor activity. It is applicable to bladder cancer research.</p>Formule :C43H58N2O13Couleur et forme :SolidMasse moléculaire :810.93NYY-6a
<p>NYY-6a is a ferroptosis (Ferroptosis) inhibitor, demonstrating significant suppression of RSL3-induced ferroptosis in 786-O and HT-1080 cells, with EC50 values of 52 nM and 50 nM, respectively. As a radical-trapping antioxidant (RTA), NYY-6a effectively reduces lipid peroxidation, comparable to ferrostatin-1 and liproxstatin-1, making it useful for research into ferroptosis-related pathologies.</p>Formule :C23H22N2O3Couleur et forme :SolidMasse moléculaire :374.43GPX4-IN-5
CAS :<p>GPX4-IN-5 is a GPX4 inhibitor with antitumor activity.GPX4-IN-5 induces iron death and may be used for the treatment of triple negative breast cancer.</p>Formule :C18H17ClFNO5Degré de pureté :99.58%Couleur et forme :SoildMasse moléculaire :381.78Ferroptosis-IN-16
<p>Ferroptosis-IN-16 (Compound 13l) acts as a specific inhibitor of ferroptosis, demonstrating EC50 values of 0.7 nM in ES-2 cells and 0.9 nM in LX-2 cells. It effectively alleviates acute liver injury induced by Acetaminophen in mouse models and shows excellent metabolic stability in mouse liver microsomes.</p>Formule :C26H23N5OCouleur et forme :SolidMasse moléculaire :421.49W1131 TFA
<p>W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.</p>Formule :C25H20F3N5O6Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :543.45PRLX-93936 HCL
CAS :<p>PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.</p>Formule :C21H26Cl2N4O2Degré de pureté :98.4% - 99.94%Couleur et forme :SolidMasse moléculaire :437.3784-B10
CAS :<p>84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.</p>Formule :C25H22F3NO5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :473.44CuATSM
CAS :<p>Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.</p>Formule :C8H14CuN6S2Couleur et forme :SolidMasse moléculaire :321.92Idebenone
CAS :Formule :C19H30O5Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :Light yellow to Brown powder to crystalMasse moléculaire :338.44CuATSP
CAS :<p>CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.</p>Formule :C18H18CuN6S2Degré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :446.05Cerivastatin sodium
CAS :<p>Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.</p>Formule :C26H33FNNaO5Degré de pureté :98.50% - 99.67%Couleur et forme :SolidMasse moléculaire :481.53CCW16
CAS :<p>CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.</p>Formule :C22H20ClNO3Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :381.85Chrysosplenetin
CAS :<p>Chrysosplenetin is a metabolic inhibitor of artemisinin.</p>Formule :C19H18O8Degré de pureté :97.43% - 98.4%Couleur et forme :SolidMasse moléculaire :374.34L-Glutamic acid monosodium salt
CAS :<p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>Formule :C5H8NO4·NaDegré de pureté :99.93%Couleur et forme :White Solid CrystallineMasse moléculaire :169.11Piperlongumine
CAS :<p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>Formule :C17H19NO5Degré de pureté :97.03% - 99.90%Couleur et forme :SolidMasse moléculaire :317.34NADPH tetracyclohexanamine
CAS :<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Formule :C45H82N11O17P3Degré de pureté :98.73% - 99.05%Couleur et forme :SolidMasse moléculaire :1142.12L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS :<p>L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.</p>Formule :C8H18N2O3SDegré de pureté :97.07% - ≥98%Couleur et forme :White Fine PowderMasse moléculaire :222.31ML-210
CAS :<p>ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.</p>Formule :C22H20Cl2N4O4Degré de pureté :97% - 99.03%Couleur et forme :SolidMasse moléculaire :475.32Piperazine Erastin
CAS :<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Formule :C35H41ClN6O4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :645.19RSL3
CAS :<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Formule :C23H21ClN2O5Degré de pureté :98% - 99.96%Couleur et forme :SolidMasse moléculaire :440.88TBHQ
CAS :TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formule :C10H14O2Degré de pureté :99.17% - 99.53%Couleur et forme :White Solid PowderMasse moléculaire :166.22Trolox
CAS :<p>Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.</p>Formule :C14H18O4Degré de pureté :98.90% - 99.90%Couleur et forme :White To Fainly Beige Crystalline PowderMasse moléculaire :250.29Alogliptin
CAS :<p>Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9</p>Formule :C18H21N5O2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :339.39Alogliptin Benzoate
CAS :<p>Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.</p>Formule :C25H27N5O4Degré de pureté :99.94% - >99.99%Couleur et forme :White PowderMasse moléculaire :461.51WITHAFERIN A
CAS :<p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>Formule :C28H38O6Degré de pureté :97.41% - 99.99%Couleur et forme :SolidMasse moléculaire :470.6Bardoxolone Methyl
CAS :<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Formule :C32H43NO4Degré de pureté :97.81% - 99.09%Couleur et forme :SolidMasse moléculaire :505.69Siramesine hydrochloride
CAS :<p>Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibit</p>Formule :C30H32ClFN2ODegré de pureté :99.72% - >99.99%Couleur et forme :SolidMasse moléculaire :491.04Necrostatin-1
CAS :<p>Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.</p>Formule :C13H13N3OSDegré de pureté :99.25% - >99.99%Couleur et forme :SolidMasse moléculaire :259.33JKE-1674
CAS :<p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>Formule :C20H20Cl2N4O4Degré de pureté :98.02% - 98.4%Couleur et forme :SolidMasse moléculaire :451.3Bay 11-7085
CAS :<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Formule :C13H15NO2SDegré de pureté :99.76% - 99.94%Couleur et forme :White SolidMasse moléculaire :249.33DL-Buthionine-(S,R)-sulfoximine
CAS :<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Formule :C8H18N2O3SDegré de pureté :98% - 99.64%Couleur et forme :White Fine PowderMasse moléculaire :222.31Coenzyme Q10
CAS :<p>Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.</p>Formule :C59H90O4Degré de pureté :99.14% - 99.88%Couleur et forme :DrypowderMasse moléculaire :863.34ML162
CAS :<p>ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.</p>Formule :C23H22Cl2N2O3SDegré de pureté :98.42% - 99.55%Couleur et forme :SolidMasse moléculaire :477.4(E)-Ferulic acid
CAS :<p>(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of</p>Formule :C10H10O4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :194.18D-glutamine
CAS :<p>D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.</p>Formule :C5H10N2O3Degré de pureté :99.99%Couleur et forme :White Or Off-White PowderMasse moléculaire :146.14BAY 87-2243
CAS :<p>BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).</p>Formule :C26H26F3N7O2Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :525.53L-Buthionine-(S,R)-sulfoximine hydrochloride
<p>L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.</p>Formule :C8H19ClN2O3SCouleur et forme :SolidMasse moléculaire :258.77Liproxstatin-1 hydrochloride
CAS :<p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>Formule :C19H22Cl2N4Couleur et forme :SolidMasse moléculaire :377.31Pioglitazone potassium
CAS :<p>Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.</p>Formule :C19H19KN2O3SCouleur et forme :SolidMasse moléculaire :394.53CDDO-Im
CAS :CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formule :C34H43N3O3Degré de pureté :98.3% - 99.61%Couleur et forme :SolidMasse moléculaire :541.72(-)-Epicatechin
CAS :<p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>Formule :C15H14O6Degré de pureté :98.55% - 98.80%Couleur et forme :SolidMasse moléculaire :290.27UAMC-3203 hydrochloride
CAS :<p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>Formule :C25H38ClN5O2SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :508.12Baicalein monohydrate
CAS :<p>Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.</p>Formule :C15H12O6Couleur et forme :SolidMasse moléculaire :288.25Ferrostatin-1
CAS :<p>Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!</p>Formule :C15H22N2O2Degré de pureté :96.1% - 99.68%Couleur et forme :SolidMasse moléculaire :262.35CIL56
CAS :<p>CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).</p>Formule :C23H27N3O5S2Degré de pureté :99.46% - 99.91%Couleur et forme :SolidMasse moléculaire :489.61Hemin
CAS :<p>Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.</p>Formule :C34H32ClFeN4O4Degré de pureté :97.169% - 99.59%Couleur et forme :Dark Purple Crystalline PowderMasse moléculaire :651.94DihydroarteMisinic acid
CAS :<p>DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal</p>Formule :C15H24O2Degré de pureté :99.06% - 99.17%Couleur et forme :SolidMasse moléculaire :236.35Arteannuin B
CAS :<p>1. Arteannuin B has potent antimalarial activity.</p>Formule :C15H20O3Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :248.32Eprenetapopt
CAS :<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Formule :C10H17NO3Degré de pureté :98.75% - 99.57%Couleur et forme :SolidMasse moléculaire :199.25DL-α-Tocopherol
CAS :<p>DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.</p>Formule :C29H50O2Degré de pureté :99.61% - 99.90%Couleur et forme :Light Yellow Liquid ViscousMasse moléculaire :430.71SRS11-92
CAS :<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Formule :C22H28N2O2Degré de pureté :98.58%Couleur et forme :SolidMasse moléculaire :352.47Deferitrin
CAS :<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Formule :C11H11NO4SDegré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :253.271R,3S-RSL 3
CAS :<p>1R,3S-RSL 3 is a harmala alkaloid.</p>Formule :C23H21ClN2O5Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :440.88Setanaxib
CAS :<p>Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.</p>Formule :C21H19ClN4O2Degré de pureté :93.468% - 99.31%Couleur et forme :SolidMasse moléculaire :394.85Dp44mT
CAS :<p>Dp44mT, a effective iron chelator, has selective antitumor activity.</p>Formule :C14H15N5SDegré de pureté :99% - 99.02%Couleur et forme :SolidMasse moléculaire :285.37Nordihydroguaiaretic acid
CAS :<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formule :C18H22O4Degré de pureté :97.82% - 99.91%Couleur et forme :SolidMasse moléculaire :302.36NADPH tetrasodium salt
CAS :<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Formule :C21H26N7Na4O17P3Degré de pureté :97.15% - >99.99%Couleur et forme :SolidMasse moléculaire :833.35Troglitazone
CAS :<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Formule :C24H27NO5SDegré de pureté :98% - 99.8%Couleur et forme :Yellow SolidMasse moléculaire :441.54SRS16-86
CAS :<p>SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.</p>Formule :C26H32N4O2Degré de pureté :97.73%Couleur et forme :SolidMasse moléculaire :432.56Pseudolaric Acid B
CAS :<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Formule :C23H28O8Degré de pureté :98.91% - 99.84%Couleur et forme :SolidMasse moléculaire :432.46Levobupivacaine
CAS :<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Formule :C18H28N2ODegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :288.43Liproxstatin-1
CAS :<p>Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).</p>Formule :C19H21ClN4Degré de pureté :97.11% - 99.44%Couleur et forme :SolidMasse moléculaire :340.85Rosiglitazone hydrochloride
CAS :<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Formule :C18H19N3O3S·HClDegré de pureté :99.63% - 99.79%Couleur et forme :SolidMasse moléculaire :393.89SP600125
CAS :<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Formule :C14H8N2ODegré de pureté :97.63% - 99.82%Couleur et forme :SolidMasse moléculaire :220.23L-Cystine
CAS :<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Formule :C6H12N2O4S2Degré de pureté :99.59% - 99.85%Couleur et forme :White Solid PowderMasse moléculaire :240.30Rosiglitazone
CAS :<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formule :C18H19N3O3SDegré de pureté :98.61% - 99.87%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.43L-Glutamic acid
CAS :<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Formule :C5H9NO4Degré de pureté :99.14% - 99.55%Couleur et forme :White Solid CrystallineMasse moléculaire :147.13ML385
CAS :<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Formule :C29H25N3O4SDegré de pureté :98.08% - >99.99%Couleur et forme :SolidMasse moléculaire :511.59Trigonelline
CAS :<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Formule :C7H7NO2Degré de pureté :97.585% - 99.49%Couleur et forme :Prisms Aqueous From Alcohol + Water SolidMasse moléculaire :137.14PRIMA-1
CAS :<p>PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.</p>Formule :C9H15NO3Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :185.22Atorvastatin hemicalcium salt
CAS :<p>Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.</p>Formule :C33H34FN2O5CaDegré de pureté :99.27% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :577.67Erastin
CAS :<p>Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!</p>Formule :C30H31ClN4O4Degré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :547.04FIN56
CAS :<p>FIN56 is a specific inducer of ferroptosis.</p>Formule :C25H31N3O5S2Degré de pureté :99.72% - 99.78%Couleur et forme :SolidMasse moléculaire :517.66PD146176
CAS :<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formule :C15H11NSDegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :237.32Pifithrin-α hydrobromide
CAS :<p>Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.</p>Formule :C16H18N2OS·HBrDegré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :367.3Pifithrin-β hydrobromide
CAS :<p>Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.</p>Formule :C16H17BrN2SDegré de pureté :99.24% - 99.74%Couleur et forme :SolidMasse moléculaire :349.29Levobupivacaine hydrochloride
CAS :<p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>Formule :C18H28N2O·HClDegré de pureté :99.74%Couleur et forme :White Crystalline PowderMasse moléculaire :324.89Ammonium iron(III) citrate
CAS :<p>Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.</p>Formule :C24H32Fe3N3O28Degré de pureté :98%Couleur et forme :Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaMasse moléculaire :978.05U-73122
CAS :<p>U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.</p>Formule :C29H40N2O3Degré de pureté :97.50%Couleur et forme :Solid Off-WhiteMasse moléculaire :464.64UAMC-3203
CAS :<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Formule :C25H37N5O2SDegré de pureté :97.052% - 99.72%Couleur et forme :SolidMasse moléculaire :471.66FINO2
CAS :<p>FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.</p>Formule :C15H28O3Degré de pureté :97.27%Couleur et forme :SoildMasse moléculaire :256.38Microtubule inhibitor 8
CAS :<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Formule :C21H15N3O2SCouleur et forme :SolidMasse moléculaire :373.43Pioglitazone-d4
CAS :<p>Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .</p>Formule :C19H20N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.46W1131
CAS :<p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>Formule :C23H19N5O4Couleur et forme :SolidMasse moléculaire :429.43YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Formule :C25H26N6OCouleur et forme :SolidMasse moléculaire :426.51Ferroptosis inducer-1
CAS :<p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>Formule :C25H21ClN2O5Couleur et forme :SolidMasse moléculaire :464.9CN128 hydrochloride
CAS :<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Formule :C15H18ClNO3Couleur et forme :SolidMasse moléculaire :295.76Anticancer agent 147
CAS :<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Formule :C32H40BrN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.58Tubulin inhibitor 30
CAS :<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Formule :C22H19N3O5Couleur et forme :SolidMasse moléculaire :405.4IM-93
CAS :<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Formule :C21H28N4O2Couleur et forme :SolidMasse moléculaire :368.47CGP 65015
CAS :<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Formule :C14H15NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :261.27FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Formule :C22H27F3N4O2SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :468.54Deferitazole
CAS :<p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>Formule :C18H25NO7SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :399.46Erastin2
CAS :<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formule :C36H35ClN4O4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :623.14HBED
CAS :<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formule :C20H24N2O6Degré de pureté :97.35% - 98.58%Couleur et forme :SolidMasse moléculaire :388.41BCP-T.A
CAS :<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formule :C23H19Cl2N3OSDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :456.39Lepadin E
CAS :<p>Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.</p>Formule :C26H47NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.66CP-24879 hydrochloride
CAS :<p>CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.</p>Formule :C11H18ClNODegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :215.72Docebenone
CAS :Docebenone is a selective and orally active inhibitor of 5-LO.Formule :C21H26O3Couleur et forme :SolidMasse moléculaire :326.43Ferroptocide
CAS :<p>Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.</p>Formule :C30H36ClN3O7Couleur et forme :SolidMasse moléculaire :586.08Ogremorphin
CAS :<p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>Formule :C21H17N3OSDegré de pureté :99.65% - 99.65%Couleur et forme :SolidMasse moléculaire :359.44Lepadin H
CAS :<p>Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing</p>Formule :C26H45NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.64viFSP1
CAS :<p>viFSP1, a species-independent FSP1 inhibitor, effectively induces ferroptosis in FSP1-dependent cells by targeting the highly conserved NAD(P)H binding pocket of FSP1, directly inhibiting its activity. This action results in lipid peroxidation and exhibits anticancer activity [1].</p>Formule :C16H17N3O3SCouleur et forme :SolidMasse moléculaire :331.39
![(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydr…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA0032AJ.webp&w=3840&q=75)
