c-Myc
Les inhibiteurs de c-Myc ciblent la protéine c-Myc, un facteur de transcription qui joue un rôle crucial dans la croissance cellulaire, la prolifération et l'apoptose. c-Myc régule l'expression de nombreux gènes impliqués dans le cycle cellulaire et est souvent surexprimé dans divers cancers, conduisant à une prolifération cellulaire incontrôlée et à la croissance tumorale. Inhiber c-Myc peut perturber ces processus, induisant un arrêt du cycle cellulaire et l'apoptose dans les cellules cancéreuses. Les inhibiteurs de c-Myc sont des outils importants dans la recherche sur le cancer et le développement thérapeutique. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de c-Myc de haute qualité pour soutenir vos recherches en oncologie, régulation du cycle cellulaire et contrôle transcriptionnel.
69 produits trouvés pour "c-Myc"
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Ceramides Mixture
CAS :<p>Ceramides Mixture: endogenous, regulates cell cycle, growth, and telomerase activity, with hydroxy/non-hydroxy fatty acids.</p>Formule :C36H71NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :581.967FIDAS-5
CAS :<p>FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.</p>Formule :C15H13ClFNDegré de pureté :97.66% - 98.3%Couleur et forme :SolidMasse moléculaire :261.72Eragidomide
CAS :<p>Eragidomide (Cereblon modulator 1) is a CRBN E3 ligase modulator, specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.</p>Formule :C22H18ClF2N3O4Degré de pureté :97.51% - 99.63%Couleur et forme :SolidMasse moléculaire :461.85MYCi361
CAS :<p>MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).</p>Formule :C26H16ClF9N2O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :594.86MYCMI-6
CAS :<p>MYCMI-6 inhibits MYC:MAX, reduces tumor growth, triggers apoptosis, minimal side effects.</p>Formule :C20H19N7ODegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :373.41MYCi975
CAS :<p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>Formule :C25H16Cl2F6N2O2Degré de pureté :99.3% - 99.82%Couleur et forme :SolidMasse moléculaire :561.3Saxagliptin hydrate
CAS :<p>Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).</p>Formule :C18H25N3O2·H2ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :333.43KJ Pyr 9
CAS :<p>KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).</p>Formule :C22H15N3O4Degré de pureté :99.56% - ≥98%Couleur et forme :SolidMasse moléculaire :385.37FIDAS-3
CAS :<p>FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities</p>Formule :C16H15F2NDegré de pureté :97.75%Couleur et forme :SolidMasse moléculaire :259.29APTO-253
CAS :<p>APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells.</p>Formule :C22H14FN5Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :367.38c-Myc inhibitor 10
CAS :<p>c-Myc inhibitor 10 enhances cell potency with improved permeability from methylated morpholine nitrogen.</p>Formule :C28H38N6O3Couleur et forme :SolidMasse moléculaire :506.64c-Myc inhibitor 5
<p>DA3: Fluorescent c-Myc inhibitor, targets c-MYC G-quadruplex (K D 16 μM), selective, suppresses c-MYC expression.</p>Formule :C30H46N12Couleur et forme :SolidMasse moléculaire :574.77Anti-c-myc Antibody (9E10)
<p>Anti-c-myc Antibody (9E10) is a chimeric mouse IgG1 antibody targeting human c-myc.</p>Couleur et forme :Odour LiquidAnticancer agent 263
<p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>Formule :C13H20N2O6Couleur et forme :SolidMasse moléculaire :300.308Cotylenin A
CAS :<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Formule :C33H50O11Couleur et forme :SolidMasse moléculaire :622.744H122
<p>H122 is a TEADPROTAC degrader effective in degrading TEAD1 with a DC50 of 3 nM, and it shows strong affinity for TEAD2, TEAD3, and TEAD4 with Ki values of 2.0, 3.6, and 1.6 nM, respectively. H122 also downregulates Myc expression and inhibits the growth of MSTO-211H and NCI-H226 cells, with IC50 values of 21.3 nM and 0.6 nM, respectively, demonstrating antitumor activity in mouse models. (Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligaseCereblon)</p>Formule :C45H45ClFN5O8Couleur et forme :SolidMasse moléculaire :838.319Methylcarbamyl PAF C-8
<p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>Couleur et forme :Odour SolidRA-V
<p>RA-V is a natural product that can be used as a reference standard.</p>Formule :C160H202N24O41Couleur et forme :SolidMasse moléculaire :3117.5VGN50
<p>VGN50 is a bioactive molecule that mimics the function of K-Rta, capable of downregulating MYC-mediated gene transcription. VGN50 exhibits antitumor activity.</p>Formule :C121H218N46O32Masse moléculaire :2827.68453MYC-IN-2
CAS :<p>MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.</p>Formule :C25H17N3O2SCouleur et forme :SolidMasse moléculaire :423.49
