Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2613 produits trouvés pour "Chromatine/Épigénétique"
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Sotrastaurin
CAS :Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formule :C25H22N6O2Degré de pureté :98% - 99.70%Couleur et forme :SolidMasse moléculaire :438.48Ref: TM-T6278
1mg44,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg135,00€25mg254,00€50mg423,00€100mg605,00€200mg845,00€AK-7
CAS :AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.Formule :C19H21BrN2O3SDegré de pureté :98.43% - 99.34%Couleur et forme :SolidMasse moléculaire :437.35Ref: TM-T5490
1mg34,00€2mg47,00€5mg71,00€1mL*10mM (DMSO)89,00€10mg100,00€25mg177,00€50mg313,00€100mg512,00€PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Formule :C78H132N30O18Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :1778.10Picolinamide
CAS :Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.Formule :C6H6N2ODegré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :122.12MS049
CAS :MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.Formule :C15H24N2ODegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :248.36Ref: TM-T4378
2mg34,00€5mg49,00€1mL*10mM (DMSO)52,00€10mg80,00€25mg149,00€50mg222,00€100mg334,00€200mg494,00€TCS-PIM-1-4a
CAS :SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formule :C11H6F3NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :273.23PTACH
CAS :PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).Formule :C20H26N2O2S2Degré de pureté :87.44% - 99.74%Couleur et forme :SolidMasse moléculaire :390.56MS023
CAS :MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,Formule :C17H25N3ODegré de pureté :98.31% - 99.87%Couleur et forme :SolidMasse moléculaire :287.4Ref: TM-T6900
1mg37,00€2mg49,00€1mL*10mM (DMSO)79,00€5mg84,00€10mg113,00€25mg230,00€50mg358,00€100mg532,00€500mg1.153,00€E1231
CAS :E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.Formule :C21H21N3O3Degré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :363.41Ref: TM-T9106
1mg34,00€5mg70,00€1mL*10mM (DMSO)94,00€10mg99,00€25mg195,00€50mg311,00€100mg449,00€500mg888,00€R59949
CAS :R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formule :C28H25F2N3OSDegré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :489.58Ref: TM-T26019
1mg39,00€2mg52,00€5mg87,00€1mL*10mM (DMSO)95,00€10mg138,00€25mg281,00€50mg425,00€100mg625,00€200mg883,00€EDO-S101
CAS :EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.Formule :C19H28Cl2N4O2Degré de pureté :98.02% - 99.44%Couleur et forme :SolidMasse moléculaire :415.36ACY-738
CAS :ACY-738 demonstrates inhibitory activity against recombinant HDAC6 (IC50: 1.7 nM), with respective average selectivity over class I HDACs being 100-fold.Formule :C14H14N4O2Degré de pureté :98.85% - 99.89%Couleur et forme :SolidMasse moléculaire :270.29Ref: TM-T3509
1mg46,00€2mg62,00€5mg90,00€1mL*10mM (DMSO)100,00€10mg165,00€25mg268,00€50mg439,00€100mg582,00€CAY10602
CAS :CAY10602 activates SIRT1, suppresses NF-κB/TNF-α in THP-1 cells with 75% efficacy at 60 μM, non-toxic.Formule :C22H15FN4O2SDegré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :418.44SKLB-23bb
CAS :SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor and also has microtubule-disrupting ability.Formule :C21H24N4O4Degré de pureté :97.58%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T5830
1mg50,00€5mg133,00€1mL*10mM (DMSO)147,00€10mg187,00€25mg304,00€50mg424,00€100mg587,00€200mg800,00€GSK121
CAS :GSK121 is an inhibitor of selective PAD4.
Formule :C25H26F3N5O3Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :501.51PJ34
CAS :PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
Formule :C17H17N3O2Degré de pureté :95.05% - 99.85%Couleur et forme :SolidMasse moléculaire :295.34TH34
CAS :TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.Formule :C15H16N2O2Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :256.3HIF-2α-IN-4
CAS :HIF-2a translation inhibitor is a compound used as a molecular building block.Formule :C9H9N3O4S2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :287.32Ref: TM-T50099
5mg37,00€1mL*10mM (DMSO)44,00€10mg60,00€25mg111,00€50mg200,00€100mg299,00€200mg430,00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formule :C25H20FN7ODegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :453.47Ref: TM-T8685
1mg88,00€5mg170,00€1mL*10mM (DMSO)177,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€200mg1.074,00€SirReal2
CAS :SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.Formule :C22H20N4OS2Degré de pureté :99.52% - 99.75%Couleur et forme :SolidMasse moléculaire :420.55Ref: TM-T6984
1mg37,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)86,00€10mg102,00€25mg187,00€50mg295,00€100mg477,00€Selisistat R-enantiomer
CAS :Selisistat R-enantiomer (EX-527 (R-enantiomer)) is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).Formule :C13H13ClN2ODegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :248.71Ref: TM-T15263
1mg101,00€2mg150,00€5mg245,00€1mL*10mM (DMSO)269,00€10mg356,00€25mg597,00€50mg835,00€100mg1.108,00€Selisistat S-enantiomer
CAS :Selisistat S-enantiomer (EX-527 S-enantiomer) is an effective and specific SIRT1 inhibitor (IC50 = 98 nM) and shows >200-fold selectivity against SIRT2/3.Formule :C13H13ClN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :248.71Ref: TM-T7058
1mg142,00€2mg203,00€5mg314,00€1mL*10mM (DMSO)359,00€10mg447,00€25mg713,00€50mg1.018,00€TPPB
CAS :TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).Formule :C27H30F3N3O3Degré de pureté :97.71% - 98.00%Couleur et forme :SolidMasse moléculaire :501.54Piribedil
CAS :Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formule :C16H18N4O2Degré de pureté :99.79% - 99.82%Couleur et forme :SolidMasse moléculaire :298.34Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Formule :C65H122N18O16SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :1443.96dBET1
CAS :dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.Formule :C38H37ClN8O7SDegré de pureté :98.02% - 99.3%Couleur et forme :SolidMasse moléculaire :785.27Ref: TM-T4495
1mg50,00€5mg99,00€1mL*10mM (DMSO)145,00€10mg161,00€25mg268,00€50mg427,00€100mg650,00€200mg888,00€HDAC-IN-3
CAS :HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.Formule :C22H33N3O4Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :403.52ZM39923 hydrochloride
CAS :ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formule :C23H25NO·HClDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :367.91Valrubicin
CAS :Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formule :C34H36F3NO13Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :723.64MK-8745
CAS :MK-8745 is a potent and selective Aurora A inhibitor.Formule :C20H19ClFN5OSDegré de pureté :99.09% - 99.79%Couleur et forme :SolidMasse moléculaire :431.91JANEX-1
CAS :JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.Formule :C16H15N3O3Degré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :297.31SGC2085
CAS :SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).Formule :C19H24N2O2Degré de pureté :99.61% - 99.71%Couleur et forme :SolidMasse moléculaire :312.41Ref: TM-T7089
1mg84,00€2mg113,00€1mL*10mM (DMSO)152,00€5mg215,00€10mg324,00€25mg533,00€50mg777,00€100mg1.071,00€CPI-1205
CAS :CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。Formule :C27H33F3N4O3Degré de pureté :98.71% - 99.7%Couleur et forme :SolidMasse moléculaire :518.57DCLX069
CAS :DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.Formule :C20H25N3O2Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :339.43Ref: TM-T27133
1mg38,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)92,00€10mg111,00€25mg187,00€50mg305,00€100mg487,00€500mg1.035,00€AZD5305
CAS :AZD5305 is a potent, selective and oral active PARP inhibitor.Formule :C22H26N6O2Degré de pureté :98.68% - 99.93%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T9165
1mg107,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg358,00€25mg597,00€50mg850,00€100mg1.153,00€Peficitinib
CAS :Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.Formule :C18H22N4O2Degré de pureté :98.67% - 99.4%Couleur et forme :SolidMasse moléculaire :326.39Ref: TM-T6933
2mg38,00€5mg63,00€1mL*10mM (DMSO)70,00€10mg99,00€25mg172,00€50mg268,00€100mg416,00€200mg610,00€E-7386
CAS :E-7386 is an oral active CBP/ -catenin modulator.Formule :C39H48FN9O4Degré de pureté :98.92% - 99.91%Couleur et forme :SolidMasse moléculaire :725.85Ref: TM-T11136
1mg93,00€2mg128,00€5mg219,00€1mL*10mM (DMSO)350,00€10mg356,00€25mg613,00€50mg873,00€100mg1.161,00€Olaparib
CAS :View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formule :C24H23FN4O3Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :434.46TP-3654
CAS :TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).Formule :C22H25F3N4ODegré de pureté :99.8% - 99.95%Couleur et forme :SolidMasse moléculaire :418.46E7449
CAS :E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.Formule :C18H15N5ODegré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T4471
1mg34,00€5mg88,00€1mL*10mM (DMSO)88,00€10mg114,00€25mg178,00€50mg269,00€100mg399,00€200mg590,00€Protosappanin A
CAS :Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Formule :C15H12O5Degré de pureté :99.42% - 99.82%Couleur et forme :SolidMasse moléculaire :272.25Ref: TM-TJS1779
1mg88,00€1mL*10mM (DMSO)178,00€5mg195,00€10mg318,00€25mg523,00€50mg743,00€100mg999,00€Molibresib
CAS :Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).Formule :C22H22ClN5O2Degré de pureté :97.70% - 99.08%Couleur et forme :SolidMasse moléculaire :423.9Ref: TM-T1906
1mg40,00€2mg54,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg118,00€25mg205,00€50mg339,00€100mg507,00€200mg712,00€500mg1.108,00€(+)-JQ1 PA
CAS :(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formule :C22H20ClN5OSDegré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :437.95WM-1119
CAS :WM-1119 is a highly potent, selective KAT6A/B inhibitorFormule :C18H13F2N3O3SDegré de pureté :96.59% - 99.58%Couleur et forme :SolidMasse moléculaire :389.38XD14
CAS :XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.
Formule :C20H27N3O5SDegré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :421.51FL-411
CAS :FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.Formule :C18H19N3O2SDegré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :341.43GSK3685032
CAS :GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).
Formule :C22H24N6OSDegré de pureté :98.56% - 99.49%Couleur et forme :SolidMasse moléculaire :420.53Daminozide
CAS :Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.Formule :C6H12N2O3Degré de pureté :99.86%Couleur et forme :White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Masse moléculaire :160.17GSK-5959
CAS :GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.Formule :C22H26N4O3Degré de pureté :98.35% - 98.65%Couleur et forme :SolidMasse moléculaire :394.47Deucravacitinib
CAS :Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.Formule :C20H19D3N8O3Degré de pureté :98.52% - >99.99%Couleur et forme :SolidMasse moléculaire :425.46Ref: TM-T14687
1mg56,00€5mg137,00€1mL*10mM (DMSO)149,00€10mg248,00€25mg389,00€50mg575,00€100mg817,00€Momelotinib
CAS :Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.Formule :C23H22N6O2Degré de pureté :97.07% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46Ref: TM-T1849
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg89,00€25mg158,00€50mg245,00€100mg385,00€200mg592,00€MS436
CAS :MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.Formule :C18H17N5O3SDegré de pureté :97.95% - 98.92%Couleur et forme :SolidMasse moléculaire :383.42Ref: TM-T1854
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg95,00€25mg172,00€50mg268,00€100mg429,00€200mg615,00€SNS-314 Mesylate
CAS :SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.Formule :C18H15ClN6OS2·CH4O3SDegré de pureté :99.44% - 99.92%Couleur et forme :SolidMasse moléculaire :527.04BAY-598
CAS :BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.Formule :C22H20Cl2F2N6O3Degré de pureté :99.18% - 99.78%Couleur et forme :SolidMasse moléculaire :525.342',3',5'-triacetyl-5-Azacytidine
CAS :2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.Formule :C14H18N4O8Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :370.31Ref: TM-T7840
2mg38,00€5mg50,00€1mL*10mM (DMSO)60,00€10mg75,00€25mg122,00€50mg177,00€100mg266,00€200mg385,00€GSK046
CAS :GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.Formule :C23H27FN2O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :414.47Ref: TM-T8932
1mg57,00€5mg120,00€1mL*10mM (DMSO)133,00€10mg200,00€25mg447,00€50mg715,00€100mg1.108,00€200mg1.485,00€RO495
CAS :RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assaysFormule :C17H14Cl2N6ODegré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :389.24Ref: TM-T22416
1mg46,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg126,00€25mg235,00€50mg344,00€100mg465,00€200mg625,00€GSK6853
CAS :GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.Formule :C22H27N5O3Degré de pureté :98.71% - 99.21%Couleur et forme :SolidMasse moléculaire :409.48(Z)-LFM-A13
CAS :(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Formule :C11H8Br2N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :360Niraparib
CAS :Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39Ref: TM-T3231
5mg57,00€1mL*10mM (DMSO)63,00€10mg84,00€25mg105,00€50mg137,00€100mg205,00€200mg304,00€500mg515,00€AKBA
CAS :AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.Formule :C32H48O5Degré de pureté :97.85% - 99.77%Couleur et forme :SolidMasse moléculaire :512.72MN-64
CAS :MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.Formule :C18H16O2Degré de pureté :99.5% - 99.93%Couleur et forme :SolidMasse moléculaire :264.32SGC0946
CAS :SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.Formule :C28H40BrN7O4Degré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :618.57SMI-16a
CAS :SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (Formule :C13H13NO3SDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :263.31Ref: TM-T3989
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)87,00€10mg93,00€25mg152,00€50mg222,00€100mg334,00€OF-1
CAS :OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.Formule :C17H18BrN3O4SDegré de pureté :98.55% - ≥95%Couleur et forme :SolidMasse moléculaire :440.31Ref: TM-T2127
1mg35,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg123,00€25mg240,00€50mg385,00€100mg595,00€200mg833,00€AT9283
CAS :AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43SETDB1-TTD-IN-1
CAS :SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.Formule :C28H31N5O2Degré de pureté :98.26% - 99.96%Couleur et forme :SolidMasse moléculaire :469.58JMJD7-IN-1
CAS :JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.Formule :C16H8Cl2N2O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :363.15PF-9366
CAS :PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).Formule :C20H19ClN4Degré de pureté :97.28% - 99.88%Couleur et forme :SolidMasse moléculaire :350.84Ref: TM-T5191
1mg46,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg130,00€25mg227,00€50mg321,00€100mg442,00€200mg642,00€AG-270
CAS :AG-270 is an allosteric and orally active inhibitor of MAT2A.Formule :C30H27N5O2Degré de pureté :98.28% - 98.87%Couleur et forme :SolidMasse moléculaire :489.57Ref: TM-T9050
2mgÀ demander1mg110,00€5mg256,00€10mg378,00€25mg628,00€50mg882,00€100mg1.225,00€200mg1.673,00€C-82
CAS :C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.Formule :C33H34N6O4Degré de pureté :98.86% - 99.66%Couleur et forme :SolidMasse moléculaire :578.66Itacitinib
CAS :Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.Formule :C26H23F4N9ODegré de pureté :96.4% - 99.5%Couleur et forme :SolidMasse moléculaire :553.51A-966492
CAS :A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.Formule :C18H17FN4ODegré de pureté :98.53% - 99.27%Couleur et forme :SolidMasse moléculaire :324.35Ref: TM-T6366
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg94,00€25mg163,00€50mg261,00€100mg374,00€200mg530,00€GSK503
CAS :GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.Formule :C31H38N6O2Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :526.67PFI-4
CAS :PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.Formule :C21H24N4O3Degré de pureté :99.53% - ≥95%Couleur et forme :SolidMasse moléculaire :380.44NI-57
CAS :NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).Formule :C19H17N3O4SDegré de pureté :99.88% - >99.99%Couleur et forme :SolidMasse moléculaire :383.42Menin-MLL inhibitor MI-2
CAS :Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.Formule :C18H25N5S2Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :375.55Ref: TM-T2649
2mg39,00€5mg58,00€1mL*10mM (DMSO)64,00€10mg84,00€25mg160,00€50mg230,00€100mg356,00€200mg522,00€Molibresib besylate
CAS :Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.Formule :C28H28ClN5O5SDegré de pureté :99.64% - 99.64%Couleur et forme :SolidMasse moléculaire :582.07Oroxylin A
CAS :Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.Formule :C16H12O5Degré de pureté :98.72% - 99.55%Couleur et forme :SolidMasse moléculaire :284.26Ref: TM-T6S1315
1mg37,00€5mg71,00€1mL*10mM (DMSO)84,00€10mg90,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€Tofacitinib
CAS :Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.Formule :C16H20N6ODegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :312.37BRD9539
CAS :BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μMFormule :C24H21N3O3Degré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :399.44Seclidemstat
CAS :Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.Formule :C20H23ClN4O4SDegré de pureté :98.28% - 99.76%Couleur et forme :SolidMasse moléculaire :450.94Ref: TM-T4527
5mg46,00€1mL*10mM (DMSO)50,00€10mg69,00€25mg114,00€50mg177,00€100mg335,00€200mg500,00€500mg807,00€Veliparib dihydrochloride
CAS :Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.Formule :C13H18Cl2N4ODegré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :317.21Remodelin
CAS :Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.Formule :C15H14N4SDegré de pureté :99.39% - 99.83%Couleur et forme :SolidMasse moléculaire :282.363Ref: TM-T3499
2mg37,00€5mg52,00€1mL*10mM (DMSO)56,00€10mg73,00€25mg123,00€50mg175,00€100mg236,00€200mg353,00€PT-2385
CAS :PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).Formule :C17H12F3NO4SDegré de pureté :98.91% - 99.55%Couleur et forme :SolidMasse moléculaire :383.34Ref: TM-T7848
1mg63,00€2mg93,00€1mL*10mM (DMSO)119,00€5mg144,00€10mg222,00€25mg379,00€50mg532,00€100mg740,00€200mg982,00€Venadaparib
CAS :Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.Formule :C23H23FN4O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :406.45Ref: TM-T9430
1mg46,00€2mg59,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg137,00€25mg268,00€50mg439,00€100mg645,00€RN-1 dihydrochloride
CAS :RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).Formule :C23H31Cl2N3O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :452.42Ruxolitinib
CAS :Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.Formule :C17H18N6Degré de pureté :99.4% - >99.99%Couleur et forme :SolidMasse moléculaire :306.36Ref: TM-T1829
5mg55,00€1mL*10mM (DMSO)62,00€10mg71,00€25mg96,00€50mg110,00€100mg146,00€200mg231,00€500mg393,00€GSK2801
CAS :GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.Formule :C20H21NO4SDegré de pureté :97.78% - 99.45%Couleur et forme :SolidMasse moléculaire :371.455-Methyl-2'-deoxycytidine
CAS :5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.Formule :C10H15N3O4Degré de pureté :99.18% - 99.69%Couleur et forme :SolidMasse moléculaire :241.242-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS :2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.Formule :C10H11NOSDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :193.275-Fluoro-2'-deoxycytidine
CAS :5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .Formule :C9H12FN3O4Degré de pureté :97.91%Couleur et forme :Fine White PowderMasse moléculaire :245.21Ref: TM-T7718
2mg34,00€5mg48,00€1mL*10mM (DMSO)50,00€10mg64,00€25mg90,00€50mg138,00€100mg200,00€200mg296,00€500mg497,00€A-366
CAS :A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.Formule :C19H27N3O2Degré de pureté :97.28% - 99.8%Couleur et forme :SolidMasse moléculaire :329.44Ref: TM-T3624
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg90,00€25mg208,00€50mg359,00€100mg530,00€UNC3866 TFA(1872382-47-2 free base)
CAS :UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.Formule :C45H67F3N6O10Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :909.046-Thioguanine
CAS :6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.Formule :C5H5N5SDegré de pureté :98.75% - >99.99%Couleur et forme :Odorless Or Almost Odorless Pale Yellow Crystalline PowderMasse moléculaire :167.19IOX4
CAS :IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)Formule :C15H16N6O3Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :328.33NEO2734
CAS :NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).Formule :C22H24F3N3O3Degré de pureté :98.72% - 98.8%Couleur et forme :SolidMasse moléculaire :435.44Ref: TM-T8658
1mg108,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€500mg2.673,00€Panaxadiol
CAS :Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.Formule :C30H52O3Degré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :460.73XL228
CAS :XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formule :C22H31N9ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :437.54Ref: TM-T17267
1mg52,00€2mg73,00€5mg94,00€1mL*10mM (DMSO)104,00€10mg141,00€25mg244,00€50mg371,00€100mg552,00€Tozasertib
CAS :Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formule :C23H28N8OSDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :464.59
