Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2235 produits trouvés pour "Chromatine/Épigénétique"
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SC99
CAS :<p>SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.</p>Formule :C15H8Cl2FN3ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :336.15BMS-P5
CAS :<p>BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.</p>Formule :C27H33ClN6O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :509.04GSK-J1
CAS :<p>GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.</p>Formule :C22H23N5O2Degré de pureté :99.23% - 99.67%Couleur et forme :SolidMasse moléculaire :389.45NCGC00244536
CAS :<p>NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).</p>Formule :C25H22N2O2Degré de pureté :97.2% - 99.72%Couleur et forme :SolidMasse moléculaire :382.45JW 55
CAS :<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Formule :C25H26N2O5Degré de pureté :99.31% - 99.76%Couleur et forme :SolidMasse moléculaire :434.48Rucaparib
CAS :<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formule :C19H18FN3ODegré de pureté :98.24% - 99.80%Couleur et forme :SolidMasse moléculaire :323.36WDR5-0103
CAS :<p>WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).</p>Formule :C21H25N3O4Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :383.44Glucosamine sulfate
CAS :<p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>Formule :C6H13NO5·H2SO4Degré de pureté :99.64%Couleur et forme :White CrystalMasse moléculaire :277.25Benzamide
CAS :<p>Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.</p>Formule :C7H7NODegré de pureté :99.66%Couleur et forme :Colorless Crystals Physical Description White Powder (Ntp 1992)Masse moléculaire :121.14JNJ-42041935
CAS :<p>JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.</p>Formule :C12H6ClF3N4O3Degré de pureté :99.58% - ≥95%Couleur et forme :SolidMasse moléculaire :346.65GSK591
CAS :<p>GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).</p>Formule :C22H28N4O2Degré de pureté :99.35% - 99.45%Couleur et forme :SolidMasse moléculaire :380.48UPF 1069
CAS :<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formule :C17H13NO3Degré de pureté :98.80% - 99.88%Couleur et forme :SolidMasse moléculaire :279.29KG-501
CAS :<p>KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).</p>Formule :C17H13ClNO5PDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :377.72IDF-11774
CAS :<p>IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).</p>Formule :C23H32N2O2Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :368.51GSK484 hydrochloride
CAS :<p>GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.</p>Formule :C27H32ClN5O3Degré de pureté :98.32% - 99.62%Couleur et forme :SolidMasse moléculaire :510.03HJ-PI01
CAS :<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Formule :C14H11NO2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :225.24TP0463518
CAS :<p>TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).</p>Formule :C20H18ClN3O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :431.83Chlorogenic Acid
CAS :<p>Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.</p>Formule :C16H18O9Degré de pureté :98.84% - 99.67%Couleur et forme :SolidMasse moléculaire :354.31TAK-632
CAS :<p>TAK-632 is a potent pan-Raf inhibitor.</p>Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52PKC-iota inhibitor 1
CAS :<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formule :C21H22N6ODegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :374.44Tazemetostat hydrobromide
CAS :<p>Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).</p>Formule :C34H45BrN4O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :653.65MR837
CAS :<p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>Formule :C16H14N2OSDegré de pureté :99.77% - 99.85%Couleur et forme :SolidMasse moléculaire :282.36ME0328
CAS :<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Formule :C19H19N3O2Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :321.37Hinokitiol
CAS :<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Formule :C10H12O2Degré de pureté :99.49% - 99.67%Couleur et forme :SolidMasse moléculaire :164.2GLPG0634 analog
CAS :<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Formule :C23H18N6O2Degré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :410.43CCT 137690
CAS :<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Formule :C26H31BrN8ODegré de pureté :98.51% - 99.89%Couleur et forme :SolidMasse moléculaire :551.48Ilorasertib
CAS :<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54KW-2449
CAS :<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Formule :C20H20N4ODegré de pureté :98.43% - 99.69%Couleur et forme :SolidMasse moléculaire :332.4UNC0642
CAS :<p>UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).</p>Formule :C29H44F2N6O2Degré de pureté :98.75% - 99.5%Couleur et forme :SolidMasse moléculaire :546.7NVP-TNKS656
CAS :<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Formule :C27H34N4O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :494.58BMS-911543
CAS :<p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>Formule :C23H28N8ODegré de pureté :97.69% - 99.98%Couleur et forme :SolidMasse moléculaire :432.52PARP1-IN-5 dihydrochloride
CAS :<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Formule :C25H26Cl2N2O5SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :537.46Ro 31-8220 Mesylate
CAS :<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formule :C25H23N5O2S·CH4O3SDegré de pureté :98.79% - 99.02%Couleur et forme :SolidMasse moléculaire :553.65Fedratinib hydrochloride hydrate
CAS :<p>Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.</p>Formule :C27H40Cl2N6O4SDegré de pureté :98.96% - 99.87%Couleur et forme :SolidMasse moléculaire :615.61PF-06651600 malonate
CAS :<p>PF-06651600 is a potent and selective JAK3 inhibitor.</p>Formule :C18H23N5O5Couleur et forme :SolidMasse moléculaire :389.41PF-06726304
CAS :<p>PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).</p>Formule :C22H21Cl2N3O3Degré de pureté :98.19% - 99.51%Couleur et forme :SolidMasse moléculaire :446.33BRD4770
CAS :<p>BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.</p>Formule :C25H23N3O3Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :413.47Rucaparib tartrate
CAS :<p>Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.</p>Formule :C23H24FN3O7Couleur et forme :SolidMasse moléculaire :473.457PFI-3
CAS :<p>PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.</p>Formule :C19H19N3O2Degré de pureté :99.58% - 99.94%Couleur et forme :SolidMasse moléculaire :321.37PIN1 inhibitor API-1
CAS :<p>API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.</p>Formule :C15H13F3N6O2Degré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :366.3UNC 669
CAS :<p>UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.</p>Formule :C15H20BrN3ODegré de pureté :97.38%Couleur et forme :SolidMasse moléculaire :338.24Windorphen
CAS :<p>Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.</p>Formule :C17H15ClO3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :302.75AG490
CAS :<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Formule :C17H14N2O3Degré de pureté :98.6% - 99.39%Couleur et forme :Yellow SolidMasse moléculaire :294.3AT-9283 HCl
CAS :<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Formule :C19H24ClN7O2Couleur et forme :SolidMasse moléculaire :417.89DL-α-Hydroxyglutaric acid disodium salt
CAS :<p>DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuran</p>Formule :C5H6Na2O5Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :192.08Filgotinib
CAS :<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Formule :C21H23N5O3SDegré de pureté :98.03% - ≥95%Couleur et forme :SolidMasse moléculaire :425.5OG-L002
CAS :<p>OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.</p>Formule :C15H15NODegré de pureté :97.05% - 98.62%Couleur et forme :SolidMasse moléculaire :225.29DMOG
CAS :<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formule :C6H9NO5Degré de pureté :80.23% - 99.98%Couleur et forme :SolidMasse moléculaire :175.14DR2313
CAS :<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Formule :C8H10N2OSDegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :182.24γ-Oryzanol
CAS :<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formule :C40H58O4Degré de pureté :mixture - mixtureCouleur et forme :White Or White Crystalline Powder OdourlessMasse moléculaire :602.9Danusertib
CAS :<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formule :C26H30N6O3Degré de pureté :97.88% - 98.79%Couleur et forme :White PowderMasse moléculaire :474.55BRD4 Inhibitor 30
CAS :<p>4-(2-fluorophenyl)-1,3-thiazol-2-one: has anti-inflammatory, antibacterial, antifungal, and antitumor properties.</p>Formule :C9H6FNOSDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :195.21AZ9482
CAS :<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formule :C26H22N6O2Degré de pureté :99.18% - 99.86%Couleur et forme :SolidMasse moléculaire :450.49Piribedil hydrochloride
CAS :<p>Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.</p>Formule :C16H19ClN4O2Couleur et forme :SolidMasse moléculaire :334.8MM-102 TFA
CAS :<p>MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.</p>Formule :C37H50F5N7O6Degré de pureté :99.4% - 99.78%Couleur et forme :SolidMasse moléculaire :783.83I-BRD9
CAS :<p>I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.</p>Formule :C22H22F3N3O3S2Degré de pureté :98.16% - 99.51%Couleur et forme :SolidMasse moléculaire :497.55Amodiaquine hydrochloride
CAS :<p>Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.</p>Formule :C20H24Cl3N3OCouleur et forme :SolidMasse moléculaire :428.78WM-8014
CAS :<p>WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.</p>Formule :C20H17FN2O3SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :384.42G007-LK
CAS :<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Formule :C25H16ClN7O3SDegré de pureté :97.63% - 98.17%Couleur et forme :SolidMasse moléculaire :529.96Remodelin hydrobromide
CAS :<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Formule :C15H15BrN4SDegré de pureté :97.22% - 99.84%Couleur et forme :SolidMasse moléculaire :363.275JQKD82
CAS :<p>JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.</p>Formule :C27H40N4O5Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :500.63Curculigoside
CAS :<p>1.</p>Formule :C22H26O11Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :466.442,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS :<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formule :C16H13Cl2N3O2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :350.21,2-Dipalmitoyl-sn-glycerol
CAS :<p>1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.</p>Formule :C35H68O5Degré de pureté :97.84% - 99.78%Couleur et forme :SolidMasse moléculaire :568.91Atractylenolide I
CAS :<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formule :C15H18O2Degré de pureté :97.55% - 99.92%Couleur et forme :SolidMasse moléculaire :230.3MPT0G211 mesylate
CAS :<p>MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.</p>Formule :C18H19N3O5SCouleur et forme :SolidMasse moléculaire :389.43CPI203
CAS :<p>CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).</p>Formule :C19H18ClN5OSDegré de pureté :99.13% - 99.77%Couleur et forme :SolidMasse moléculaire :399.9WHI-P97
CAS :<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Formule :C16H13Br2N3O3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :455.1ZM-447439
CAS :<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Formule :C29H31N5O4Degré de pureté :99.11% - 99.59%Couleur et forme :Pale Yellow SolidMasse moléculaire :513.59GN44028
CAS :<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formule :C18H15N3O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :305.33Pacritinib
CAS :<p>Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).</p>Formule :C28H32N4O3Degré de pureté :99.25% - 99.49%Couleur et forme :SolidMasse moléculaire :472.58Pyridone 6
CAS :<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Formule :C18H16FN3ODegré de pureté :97.1% - 98.74%Couleur et forme :SolidMasse moléculaire :309.34Phthalazinone pyrazole
CAS :<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formule :C18H15N5ODegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :317.34JQ-1 (carboxylic acid)
CAS :<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Formule :C19H17ClN4O2SDegré de pureté :99.14% - 99.9%Couleur et forme :SolidMasse moléculaire :400.88MRTX-1719
CAS :<p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>Formule :C23H18ClFN6O2Degré de pureté :98.27% - 99.18%Couleur et forme :SolidMasse moléculaire :464.88Bisindolylmaleimide IV
CAS :<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Formule :C20H13N3O2Degré de pureté :98.83%Couleur et forme :Dark Red SolidMasse moléculaire :327.341,5-Isoquinolinediol
CAS :<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formule :C9H7NO2Degré de pureté :98.29% - 99.35%Couleur et forme :Of White To White PowderMasse moléculaire :161.16FM-381
CAS :<p>FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.</p>Formule :C24H24N6O2Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :428.49AZ6102
CAS :<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Formule :C25H28N6ODegré de pureté :97.98% - 99.91%Couleur et forme :SolidMasse moléculaire :428.53666-15
CAS :<p>666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.</p>Formule :C33H31Cl2N3O5Degré de pureté :99.41% - 99.88%Couleur et forme :SolidMasse moléculaire :620.52TCS7010
CAS :<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Formule :C31H31ClFN7O2Degré de pureté :98.49% - 99.62%Couleur et forme :SolidMasse moléculaire :588.07Upadacitinib
CAS :<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Formule :C17H19F3N6ODegré de pureté :98.96% - 99.94%Couleur et forme :SolidMasse moléculaire :380.37OAC1
CAS :<p>OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.</p>Formule :C14H11N3ODegré de pureté :99.49% - 99.65%Couleur et forme :SolidMasse moléculaire :237.26Fraxinellone
CAS :<p>1.</p>Formule :C14H16O3Degré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :232.27WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Formule :C16H14Br2ClN3O3Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :491.56Nicotinamide Hydrochloride
CAS :<p>Nicotinamide Hydrochloride, a vitamin B3 form, inhibits SIRT2 and melanoma growth, enhancing NAD+, ATP, ROS, and survival in melanoma mice.</p>Formule :C6H7ClN2OCouleur et forme :SolidMasse moléculaire :158.59SGC-SMARCA-BRDVIII
CAS :<p>SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,</p>Formule :C19H25N5O3Degré de pureté :99.54% - 99.92%Couleur et forme :SolidMasse moléculaire :371.43BD750
CAS :<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Formule :C14H13N3OSDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :271.34Pim1/AKK1-IN-1
CAS :<p>Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.</p>Formule :C20H13N5ODegré de pureté :97.03% - 98.69%Couleur et forme :SolidMasse moléculaire :339.35PJ34 hydrochloride
CAS :<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formule :C17H18ClN3O2Degré de pureté :98.87% - ≥95%Couleur et forme :SolidMasse moléculaire :331.8Hispidulin
CAS :<p>Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).</p>Formule :C16H12O6Degré de pureté :98.53% - 99.87%Couleur et forme :SolidMasse moléculaire :300.26Iniparib
CAS :<p>Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).</p>Formule :C7H5IN2O3Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :292.03Perindopril
CAS :<p>Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.</p>Formule :C19H32N2O5Couleur et forme :White PowderMasse moléculaire :368.47SAR-20347
CAS :<p>SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).</p>Formule :C21H18ClFN4O4Degré de pureté :98.99% - 99.77%Couleur et forme :SolidMasse moléculaire :444.84MK-8617
CAS :<p>MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).</p>Formule :C24H21N5O4Degré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :443.45ABBV-744
CAS :<p>ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.</p>Formule :C28H30FN3O4Degré de pureté :97.03% - >99.99%Couleur et forme :SolidMasse moléculaire :491.55RK-287107
CAS :<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Formule :C22H26F2N4O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :416.46EED226
CAS :<p>EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.</p>Formule :C17H15N5O3SDegré de pureté :98.14% - 99.33%Couleur et forme :SolidMasse moléculaire :369.4CPI-637
CAS :<p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>Formule :C22H22N6ODegré de pureté :99.89% - 99.95%Couleur et forme :SolidMasse moléculaire :386.45Anacardic Acid
CAS :<p>Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases.</p>Formule :C22H36O3Degré de pureté :97.47% - 99.87%Couleur et forme :SolidMasse moléculaire :348.52
