
Chromatine/Épigénétique
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2616 produits trouvés pour "Chromatine/Épigénétique"
TCS-PIM-1-4a
CAS :SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formule :C11H6F3NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :273.23G5-7
CAS :G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39Ref: TM-T8742
1mg35,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€Decernotinib
CAS :Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.Formule :C18H19F3N6ODegré de pureté :99.28% - >99.99%Couleur et forme :SolidMasse moléculaire :392.38Ref: TM-T2636
1mg34,00€2mg48,00€5mg71,00€1mL*10mM (DMSO)79,00€10mg99,00€25mg197,00€50mg295,00€100mg447,00€Citarinostat
CAS :ACY-241 (Citarinostat), a potent oral HDAC inhibitor, may induce tumor cell death and block growth by altering gene expression.Formule :C24H26ClN5O3Degré de pureté :98.06% - 99.06%Couleur et forme :SolidMasse moléculaire :467.95LLY-507
CAS :LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Formule :C36H42N6ODegré de pureté :99.58% - 99.93%Couleur et forme :SolidMasse moléculaire :574.76Ref: TM-T6879
1mg42,00€2mg52,00€5mg80,00€1mL*10mM (DMSO)104,00€10mg131,00€25mg289,00€50mg522,00€100mg747,00€GSK1324726A
CAS :GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).
Formule :C25H23ClN2O3Degré de pureté :98.34% - 99.85%Couleur et forme :SolidMasse moléculaire :434.91ZM39923 hydrochloride
CAS :ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formule :C23H25NO·HClDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :367.91(E/Z)-Zotiraciclib
CAS :(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formule :C23H24N4ODegré de pureté :97.75% - 99.92%Couleur et forme :SolidMasse moléculaire :372.46Ref: TM-T21503
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg113,00€25mg200,00€50mg330,00€100mg480,00€Tasquinimod
CAS :Tasquinimod (ABR-215050) is an oral antiangiogenic agent and S100A9 inhibitor that binds to the HDAC4Zn2+ binding structural domain with Kd values ranging from 10 to 30 nM.Cost-effective and quality-assured.Formule :C20H17F3N2O4Degré de pureté :99.22% - >99.99%Couleur et forme :SolidMasse moléculaire :406.36Ref: TM-T6695
1mg52,00€2mg67,00€5mg101,00€1mL*10mM (DMSO)110,00€10mg158,00€25mg295,00€50mg484,00€100mg745,00€3,6-Dihydroxyflavone
CAS :3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Formule :C15H10O4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :254.24653-47 hydrochloride
CAS :653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).Formule :C20H20Cl2N2O3Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :407.29Ref: TM-T8890
1mg87,00€5mg177,00€1mL*10mM (DMSO)203,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€500mg2.205,00€Piribedil hydrochloride
CAS :Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.Formule :C16H19ClN4O2Couleur et forme :SolidMasse moléculaire :334.8YK-3-237
CAS :YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferativeFormule :C19H21BO7Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :372.18Ref: TM-T9320
2mg38,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg93,00€25mg170,00€50mg289,00€100mg507,00€200mg655,00€500mg1.018,00€4-(3-Chlorophenyl)-2(3H)-thiazolone
CAS :4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one: a thiazole used to make antifungals, antivirals, and anti-inflammatories.Formule :C9H6ClNOSDegré de pureté :95.311%Couleur et forme :SolidMasse moléculaire :211.67AMG-47a
CAS :AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56ML324
CAS :ML324(IC50=920 nM) is a specific inhibitor of jumonji histone demethylase (JMJD2).Formule :C21H23N3O2Degré de pureté :98.22% - 98.57%Couleur et forme :SolidMasse moléculaire :349.43Ref: TM-T6593
2mg34,00€5mg49,00€10mg74,00€1mL*10mM (DMSO)79,00€25mg122,00€50mg205,00€100mg334,00€200mg494,00€PFI-2 hydrochloride
CAS :PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formule :C23H26ClF4N3O3SDegré de pureté :99.31% - 99.91%Couleur et forme :SolidMasse moléculaire :535.98Ref: TM-T4583
1mg38,00€2mg49,00€5mg80,00€10mg111,00€1mL*10mM (DMSO)122,00€25mg200,00€50mg358,00€100mg523,00€500mg1.108,00€TMP195
CAS :TMP195 (TFMO 2) is a selective class IIa histone deacetylase (HDAC) inhibitor.Formule :C23H19F3N4O3Degré de pureté :98.92% - 99.64%Couleur et forme :SolidMasse moléculaire :456.42Ref: TM-T3983
2mg70,00€5mg104,00€1mL*10mM (DMSO)104,00€10mg170,00€25mg341,00€50mg409,00€100mg602,00€200mg857,00€4-amino-1,8-Naphthalimide
CAS :4-amino-1,8-Naphthalimide (4-ANI) is a PARP inhibitor with IC50 of 180 nMFormule :C12H8N2O2Degré de pureté :95.13%Couleur et forme :Yellow Solid PowderMasse moléculaire :212.2JNJ-42041935
CAS :JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.Formule :C12H6ClF3N4O3Degré de pureté :99.58% - ≥95%Couleur et forme :SolidMasse moléculaire :346.65Ref: TM-T3180
1mg40,00€2mg52,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg119,00€25mg210,00€50mg354,00€100mg567,00€500mg1.198,00€Niraparib tosylate monohyrate
CAS :Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Formule :C26H30N4O5SDegré de pureté :97.7% - 99.99%Couleur et forme :SolidMasse moléculaire :510.61Ref: TM-T9497
5mg57,00€1mL*10mM (DMSO)66,00€10mg82,00€25mg111,00€50mg137,00€100mg205,00€200mg309,00€500mg515,00€BMS-P5 free base
CAS :BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor.Formule :C27H32N6O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :472.58MK-3903
CAS :MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Formule :C27H19ClN2O3Degré de pureté :98.63% - 99.75%Couleur et forme :SolidMasse moléculaire :454.9Ref: TM-T5187
1mg34,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg178,00€50mg334,00€100mg557,00€200mg790,00€RG2833
CAS :RG2833 (RGFP109) (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.Formule :C20H25N3O2Degré de pureté :99% - 99.50%Couleur et forme :SolidMasse moléculaire :339.43SRT 2104
CAS :SRT 2104 (GSK2245840) is a selective and brain-permeable SIRT1 activator.Formule :C26H24N6O2S2Degré de pureté :98.34% - 99.82%Couleur et forme :SolidMasse moléculaire :516.64Ref: TM-T6679
1mg43,00€5mg93,00€10mg124,00€25mg219,00€50mg358,00€100mg533,00€200mg763,00€500mg1.161,00€1g1.558,00€TMP269
CAS :TMP269: Class IIa HDAC inhibitor; HDAC4 IC50=157 nM, HDAC5 IC50=97 nM, HDAC7 IC50=43 nM, HDAC9 IC50=23 nM.Formule :C25H21F3N4O3SDegré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :514.52Ref: TM-T1857
2mg69,00€5mg90,00€1mL*10mM (DMSO)115,00€10mg153,00€25mg246,00€50mg444,00€100mg537,00€200mg773,00€500mg1.161,00€BAY 87-2243
CAS :BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formule :C26H26F3N7O2Degré de pureté :98% - 99.95%Couleur et forme :SolidMasse moléculaire :525.53Ref: TM-T2488
1mg34,00€2mg40,00€5mg59,00€1mL*10mM (DMSO)70,00€10mg96,00€25mg200,00€50mg334,00€100mg557,00€IOX2
CAS :IOX2 is a selective HIF PHD inhibitor, active in cells with 21 nM IC50 for PHD2/ELGN-1, not inhibiting FIH at 20uM.Formule :C19H16N2O5Degré de pureté :98% - 99.59%Couleur et forme :SolidMasse moléculaire :352.34HDAC-IN-7
CAS :HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide.Formule :C22H19FN4O2Degré de pureté :97.64% - 98.45%Couleur et forme :SolidMasse moléculaire :390.41Ref: TM-T2025
1mg58,00€2mg82,00€1mL*10mM (DMSO)111,00€5mg130,00€10mg215,00€25mg429,00€50mg628,00€100mg893,00€Eicosapentaenoic Acid sodium
CAS :EPA sodium, an oral omega-3, demethylates DNA, reactivates tumor suppressors, and induces vasodilation.Formule :C20H29NaO2Couleur et forme :SolidMasse moléculaire :324.43AGK7
CAS :AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.Formule :C23H13Cl2N3O2Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :434.27OTS186935 hydrochloride
OTS186935 HCl inhibits SUV39H2 (IC50 6.49 nM), curbs tumor growth in mice, and modulates γ-H2AX in cancer cells.Formule :C25H27Cl2N5O2Couleur et forme :SolidMasse moléculaire :522.31JAK3-IN-6
CAS :JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15 nMFormule :C19H18N4O3Degré de pureté :99.94% - 99.94%Couleur et forme :SolidMasse moléculaire :350.37OUL35
CAS :OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.Formule :C14H12N2O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :256.26AT-9283 HCl
CAS :AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.Formule :C19H24ClN7O2Couleur et forme :SolidMasse moléculaire :417.89Perindopril
CAS :Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.Formule :C19H32N2O5Couleur et forme :White PowderMasse moléculaire :368.47HNHA
CAS :HNHA is an inhibitor of HDAC.Formule :C17H21NO2SDegré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :303.42TIQ-A
CAS :TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.Formule :C11H7NOSDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :201.24Ref: TM-T50098
1mg52,00€5mg92,00€1mL*10mM (DMSO)96,00€10mg161,00€25mg290,00€50mg414,00€100mg532,00€200mg737,00€4'-Methoxychalcone
CAS :4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.Formule :C16H14O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :238.28Nexturastat A
CAS :Nexturastat A is an effective and specific HDAC6 inhibitor (IC50: 5 nM). Its selectivity is >190-fold than other HDACs.Formule :C19H23N3O3Degré de pureté :99.40% - 99.57%Couleur et forme :SolidMasse moléculaire :341.4TG101209
CAS :TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formule :C26H35N7O2SDegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :509.67GSK-J4 Hydrochloride
CAS :GSK-J4 Hydrochloride (GSK J4 HCl) is a cell permeable, potent and selective histone demethylase(JMJD3 )inhibitor. It is an ethyl ester derivative of the GSK-J1.Formule :C24H28ClN5O2Degré de pureté :97.95% - 98.23%Couleur et forme :SolidMasse moléculaire :453.97Ref: TM-T4383
1mg38,00€2mg50,00€5mg84,00€10mg120,00€1mL*10mM (DMSO)132,00€25mg207,00€50mg344,00€100mg505,00€200mg707,00€CXD101
CAS :CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class IIFormule :C24H29N5ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :403.52PLX51107
CAS :PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).Formule :C26H22N4O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :438.48Ref: TM-TQ0253
1mg52,00€2mg77,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg178,00€25mg313,00€50mg464,00€100mg672,00€BMS-P5
CAS :BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.Formule :C27H33ClN6O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :509.04Ref: TM-T22277
2mg44,00€5mg86,00€1mL*10mM (DMSO)96,00€10mg136,00€25mg268,00€50mg479,00€100mg760,00€200mg1.018,00€Rucaparib
CAS :Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.Formule :C19H18FN3ODegré de pureté :98.24% - 99.80%Couleur et forme :SolidMasse moléculaire :323.36Ref: TM-T4463
2mg46,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg109,00€25mg170,00€50mg222,00€100mg344,00€200mg512,00€500mg823,00€JW 55
CAS :JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2Formule :C25H26N2O5Degré de pureté :99.31% - 99.76%Couleur et forme :SolidMasse moléculaire :434.48GSK591
CAS :GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).Formule :C22H28N4O2Degré de pureté :99.35% - 99.45%Couleur et forme :SolidMasse moléculaire :380.48Ref: TM-T6853
1mg46,00€2mg58,00€5mg95,00€1mL*10mM (DMSO)101,00€10mg137,00€25mg268,00€50mg404,00€100mg567,00€NKL 22
CAS :NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.Formule :C19H23N3O2Degré de pureté :96.16% - 96.24%Couleur et forme :SolidMasse moléculaire :325.4IDF-11774
CAS :IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).Formule :C23H32N2O2Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :368.51SC99
CAS :SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Formule :C15H8Cl2FN3ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :336.15Ref: TM-T8719
1mg43,00€5mg87,00€1mL*10mM (DMSO)94,00€10mg133,00€25mg227,00€50mg344,00€100mg429,00€200mg597,00€GSK2879552 2HCl (1401966-69-5(free base))
GSK2879552 is an orally available, irreversible inhibitor of lysine specific demethylase 1 (LSD1), with potential antineoplastic activity.
Formule :C23H30Cl2N2O2Degré de pureté :99.87% - ≥95%Couleur et forme :SolidMasse moléculaire :437.41Ref: TM-T4418
1mg59,00€2mg86,00€5mg109,00€10mg175,00€25mg293,00€50mg411,00€100mg610,00€500mg1.301,00€FM-381
CAS :FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.Formule :C24H24N6O2Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :428.49Ref: TM-T5091
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)107,00€10mg128,00€25mg212,00€50mg319,00€100mg485,00€XL019
CAS :XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formule :C25H28N6O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :444.53Ref: TM-T3072
2mg43,00€5mg63,00€1mL*10mM (DMSO)78,00€10mg92,00€25mg150,00€50mg215,00€100mg321,00€200mg477,00€OSS_128167
CAS :OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).Formule :C19H14N2O6Degré de pureté :97.47% - 98.6%Couleur et forme :SolidMasse moléculaire :366.32Benzamide
CAS :Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.Formule :C7H7NODegré de pureté :99.66%Couleur et forme :Colorless Crystals Physical Description White Powder (Ntp 1992)Masse moléculaire :121.14LMK-235
CAS :LMK-235 is a potent HDAC inhibitor, and is used in cancer research.Formule :C15H22N2O4Degré de pureté :98.18% - 99.68%Couleur et forme :SolidMasse moléculaire :294.35Ref: TM-T6061
1mL*10mM (DMSO)49,00€5mg52,00€10mg74,00€25mg132,00€50mg222,00€100mg403,00€200mg593,00€500mg888,00€ITSA-1
CAS :ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.Formule :C13H7Cl2N3ODegré de pureté :99.78% - 99.89%Couleur et forme :SolidMasse moléculaire :292.12Ref: TM-T3358
10mg34,00€1mL*10mM (DMSO)54,00€25mg66,00€50mg90,00€100mg152,00€200mg219,00€500mg358,00€SirReal2
CAS :SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.Formule :C22H20N4OS2Degré de pureté :99.52% - 99.75%Couleur et forme :SolidMasse moléculaire :420.55Ref: TM-T6984
1mg37,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)86,00€10mg102,00€25mg187,00€50mg295,00€100mg477,00€TAK-632
CAS :TAK-632 is a potent pan-Raf inhibitor.Formule :C27H18F4N4O3SDegré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :554.52RGFP966
CAS :RGFP966 is an HDAC3 inhibitor (IC50: 0.08 μM) and does not affect other HDACs at concentrations up to 15 μM.Formule :C21H19FN4ODegré de pureté :99.2% - 99.88%Couleur et forme :SolidMasse moléculaire :362.4Ref: TM-T1762
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg99,00€25mg160,00€50mg245,00€100mg356,00€KG-501
CAS :KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).Formule :C17H13ClNO5PDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :377.72RGB-286638 free base
CAS :RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formule :C29H35N7O4Degré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :545.63Tazemetostat hydrobromide
CAS :Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).Formule :C34H45BrN4O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :653.65Ref: TM-T17002
2mg40,00€5mg57,00€10mg77,00€1mL*10mM (DMSO)79,00€50mg90,00€100mg150,00€200mg219,00€500mg358,00€ORY1001
CAS :ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.Formule :C15H22N2·2HClDegré de pureté :99.85% - 99.96%Couleur et forme :SolidMasse moléculaire :303.27Ref: TM-T6922
1mg56,00€2mg79,00€5mg127,00€1mL*10mM (DMSO)127,00€10mg221,00€25mg427,00€50mg625,00€100mg889,00€500mg1.783,00€Curculigoside
CAS :1.Formule :C22H26O11Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :466.44Hinokitiol
CAS :Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.Formule :C10H12O2Degré de pureté :99.49% - 99.98%Couleur et forme :SolidMasse moléculaire :164.2M344
CAS :M344 (Histone Deacetylase Inhibitor III) is a potent HDAC inhibitor with IC50 of 100 nM and able to induce cell differentiation.Formule :C16H25N3O3Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :307.39KW-2449
CAS :KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Formule :C20H20N4ODegré de pureté :98.43% - 99.69%Couleur et forme :SolidMasse moléculaire :332.4FG-2216
CAS :FG-2216 (YM-311) is a HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme; orally bioavailable and induced reversible and significant Epo induction in vivo.Formule :C12H9ClN2O4Degré de pureté :97.1% - >99.99%Couleur et forme :SolidMasse moléculaire :280.66CYC-116
CAS :CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormule :C18H20N6OSDegré de pureté :97.36% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46AK-1
CAS :AK-1: SIRT2 inhibitor, IC50 12.5 μM, hinders Alzheimer's neurodegeneration, arrests colon cancer cell cycle.Formule :C19H21N3O5SDegré de pureté :98.32% - 99.44%Couleur et forme :SolidMasse moléculaire :403.45Pep2m, myristoylated acetate
Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.Formule :C65H122N18O16SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :1443.96GSK 690 Hydrochloride
CAS :GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.Formule :C24H24ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.92CCT 137690
CAS :CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formule :C26H31BrN8ODegré de pureté :98.51% - 99.89%Couleur et forme :SolidMasse moléculaire :551.48UNC0642
CAS :UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).Formule :C29H44F2N6O2Degré de pureté :98.75% - 99.5%Couleur et forme :SolidMasse moléculaire :546.7Ref: TM-T4166
1mg38,00€2mg50,00€5mg82,00€1mL*10mM (DMSO)89,00€10mg124,00€25mg219,00€50mg358,00€100mg537,00€200mg782,00€Darovasertib
CAS :Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).Formule :C22H23F3N8ODegré de pureté :98.72% - ≥95%Couleur et forme :SolidMasse moléculaire :472.47C646
CAS :C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay).Formule :C24H19N3O6Degré de pureté :98% - 99.21%Couleur et forme :SolidMasse moléculaire :445.42Ref: TM-T2452
2mg46,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg92,00€25mg185,00€50mg360,00€100mg532,00€500mg1.144,00€AZ9482
CAS :AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.Formule :C26H22N6O2Degré de pureté :99.18% - 99.86%Couleur et forme :SolidMasse moléculaire :450.49Ref: TM-T22264
1mg54,00€5mg124,00€1mL*10mM (DMSO)133,00€10mg193,00€25mg369,00€50mg535,00€100mg780,00€BMS-911543
CAS :BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.Formule :C23H28N8ODegré de pureté :97.69% - 99.98%Couleur et forme :SolidMasse moléculaire :432.52SIS17
CAS :SIS17: Potent, selective HDAC11 inhibitor (IC50: 0.83 μM), blocks serine hydroxymethyl transferase 2 demyristoylation, spares other HDACs.Formule :C21H38N2OSDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :366.6Remetinostat
CAS :Remetinostat (SHP-141), a hydroxamic acid-based inhibitor of histone deacetylase enzymes, is currently being developed for the treatment of cutaneous T-cellFormule :C16H21NO6Degré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :323.34Thiomyristoyl
CAS :Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.Formule :C34H51N3O3SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :581.85Ref: TM-T3447
1mg54,00€2mg73,00€5mg92,00€10mg117,00€1mL*10mM (DMSO)117,00€25mg215,00€50mg360,00€100mg537,00€Brevilin A
CAS :Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formule :C20H26O5Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :346.42Ref: TM-T4672
1mg90,00€5mg203,00€1mL*10mM (DMSO)224,00€10mg350,00€25mg578,00€50mg797,00€100mg1.071,00€500mg2.187,00€PARP1-IN-5 dihydrochloride
CAS :PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.Formule :C25H26Cl2N2O5SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :537.46PKC-θ inhibitor hcl
CAS :PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).Formule :C20H26ClF3N6O3Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :490.91Ref: TM-T5817
1mg88,00€2mg114,00€5mg220,00€10mg356,00€25mg595,00€50mg848,00€100mg1.153,00€500mg2.305,00€CAY10603
CAS :CAY10603 (BML-281) is a potent and selective inhibitor of HDAC6.Formule :C22H30N4O6Degré de pureté :95.75% - 98.1%Couleur et forme :SolidMasse moléculaire :446.5Ref: TM-T1983
1mg59,00€2mg78,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg161,00€25mg290,00€50mg492,00€100mg710,00€Rucaparib tartrate
CAS :Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.Formule :C23H24FN3O7Couleur et forme :SolidMasse moléculaire :473.457PFI-3
CAS :PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.Formule :C19H19N3O2Degré de pureté :99.58% - 99.94%Couleur et forme :SolidMasse moléculaire :321.37TP0463518
CAS :TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).Formule :C20H18ClN3O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :431.83Protein Kinase C 19-31 acetate
PKC 19-31 acetate, a serine-altered PKCa-derived PKC inhibitor, tests PKC activity.Formule :C69H122N26O18Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :1603.9Valrubicin
CAS :Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formule :C34H36F3NO13Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :723.64Windorphen
CAS :Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.Formule :C17H15ClO3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :302.75MC1568
CAS :MC1568 is a specific HDAC inhibitor for maize HD1-A (IC50: 100 nM, in a cell-free assay). It is 34-fold more selective for HD1-A than HD1-B.Formule :C17H15FN2O3Degré de pureté :89.82% - ≥95%Couleur et forme :SolidMasse moléculaire :314.31Fedratinib hydrochloride hydrate
CAS :Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formule :C27H40Cl2N6O4SDegré de pureté :98.96% - 99.87%Couleur et forme :SolidMasse moléculaire :615.61ME0328
CAS :ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.Formule :C19H19N3O2Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :321.37HDAC8-IN-1
CAS :MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines.Formule :C22H19NO3Degré de pureté :97.13% - 99.19%Couleur et forme :SolidMasse moléculaire :345.39Ref: TM-T7082
1mg34,00€5mg63,00€1mL*10mM (DMSO)70,00€10mg95,00€25mg172,00€50mg259,00€100mg330,00€200mg467,00€DL-α-Hydroxyglutaric acid disodium salt
CAS :DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuranFormule :C5H6Na2O5Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :192.08CP21R7
CAS :CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Formule :C19H15N3O2Degré de pureté :96.14% - 99.16%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T3684
1mg38,00€2mg50,00€1mL*10mM (DMSO)77,00€5mg84,00€10mg120,00€25mg236,00€50mg356,00€100mg537,00€AG490
CAS :AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Formule :C17H14N2O3Degré de pureté :98.6% - 99.85%Couleur et forme :Yellow SolidMasse moléculaire :294.3SRT 1720 dihydrochloride
CAS :SRT 1720 dihydrochloride is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).Formule :C25H25Cl2N7OSDegré de pureté :98.58%Couleur et forme :SolidMasse moléculaire :542.48Tucidinostat
CAS :Tucidinostat is an oral HDAC1/2/3/10 inhibitor (IC50: 67-160 nM), weaker on HDAC8/11, inactive on HDAC4/5/6/7/9.Formule :C22H19FN4O2Degré de pureté :97.01% - 99.95%Couleur et forme :SolidMasse moléculaire :390.41Ref: TM-T4481
5mg60,00€1mL*10mM (DMSO)60,00€10mg95,00€25mg159,00€50mg250,00€100mg399,00€200mg558,00€500mg832,00€TH34
CAS :TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.Formule :C15H16N2O2Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :256.3ZIP acetate(863987-12-6 free base)
ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.Formule :C92H158N30O19Degré de pureté :94.68%Couleur et forme :SolidMasse moléculaire :1988.43Filgotinib
CAS :Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.Formule :C21H23N5O3SDegré de pureté :98.03% - ≥95%Couleur et forme :SolidMasse moléculaire :425.5OG-L002
CAS :OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.Formule :C15H15NODegré de pureté :97.05% - 98.62%Couleur et forme :SolidMasse moléculaire :225.29Danusertib
CAS :Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.Formule :C26H30N6O3Degré de pureté :97.88% - 98.79%Couleur et forme :White PowderMasse moléculaire :474.55(S)-CPI203
CAS :CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formule :C19H18ClN5OSDegré de pureté :99.01% - 99.92%Couleur et forme :SolidMasse moléculaire :399.9Ref: TM-T6026
2mg34,00€5mg55,00€1mL*10mM (DMSO)58,00€10mg89,00€25mg170,00€50mg269,00€100mg424,00€200mg593,00€MPT0G211 mesylate
CAS :MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.Formule :C18H19N3O5SCouleur et forme :SolidMasse moléculaire :389.43MM-102 TFA
CAS :MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.Formule :C37H50F5N7O6Degré de pureté :99.4% - 99.78%Couleur et forme :SolidMasse moléculaire :783.83Ref: TM-T8768
1mg37,00€2mg49,00€5mg100,00€1mL*10mM (DMSO)141,00€10mg165,00€25mg269,00€50mg399,00€100mg587,00€UNC 669
CAS :UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.Formule :C15H20BrN3ODegré de pureté :97.38%Couleur et forme :SolidMasse moléculaire :338.24G007-LK
CAS :G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.Formule :C25H16ClN7O3SDegré de pureté :97.63% - 98.17%Couleur et forme :SolidMasse moléculaire :529.96Ref: TM-T6842
1mg50,00€2mg66,00€5mg94,00€1mL*10mM (DMSO)116,00€10mg158,00€25mg315,00€50mg502,00€100mg707,00€γ-Oryzanol
CAS :γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in theFormule :C40H58O4Degré de pureté :mixture - mixtureCouleur et forme :White Or White Crystalline Powder OdourlessMasse moléculaire :602.9DR2313
CAS :DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.Formule :C8H10N2OSDegré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :182.24JQKD82
CAS :JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.Formule :C27H40N4O5Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :500.63Pacritinib
CAS :Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formule :C28H32N4O3Degré de pureté :99.25% - 99.49%Couleur et forme :SolidMasse moléculaire :472.58CPI203
CAS :CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).Formule :C19H18ClN5OSDegré de pureté :99.13% - 99.77%Couleur et forme :SolidMasse moléculaire :399.9PHD-1-IN-1
CAS :PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM).Formule :C13H8N4Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :220.23Ref: TM-T9627
1mg42,00€1mL*10mM (DMSO)90,00€5mg92,00€10mg132,00€25mg231,00€50mg349,00€100mg522,00€200mg710,00€RO8191
CAS :RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.Formule :C14H5F6N5ODegré de pureté :98% - 98.85%Couleur et forme :SolidMasse moléculaire :373.21Ref: TM-T22142
1mg43,00€2mg55,00€5mg93,00€10mg137,00€25mg254,00€50mg380,00€100mg573,00€500mg1.189,00€ZM-447439
CAS :ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Formule :C29H31N5O4Degré de pureté :99.11% - 99.59%Couleur et forme :Pale Yellow SolidMasse moléculaire :513.59UPF 1069
CAS :UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.Formule :C17H13NO3Degré de pureté :98.80% - 99.88%Couleur et forme :SolidMasse moléculaire :279.29Pinometostat
CAS :Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective and quality assured.Formule :C30H42N8O3Degré de pureté :99.19% - 99.86%Couleur et forme :SolidMasse moléculaire :562.71Bisindolylmaleimide IV
CAS :Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
Formule :C20H13N3O2Degré de pureté :98.83%Couleur et forme :Dark Red SolidMasse moléculaire :327.34AZ6102
CAS :AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.Formule :C25H28N6ODegré de pureté :97.98% - 99.91%Couleur et forme :SolidMasse moléculaire :428.53E7449
CAS :E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.Formule :C18H15N5ODegré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :317.34Ref: TM-T4471
1mg34,00€5mg88,00€1mL*10mM (DMSO)88,00€10mg114,00€25mg178,00€50mg269,00€100mg399,00€200mg590,00€Protosappanin A
CAS :Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.Formule :C15H12O5Degré de pureté :99.42% - 99.82%Couleur et forme :SolidMasse moléculaire :272.25Ref: TM-TJS1779
1mg88,00€1mL*10mM (DMSO)178,00€5mg195,00€10mg318,00€25mg523,00€50mg743,00€100mg999,00€XD14
CAS :XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.
Formule :C20H27N3O5SDegré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :421.51OAC1
CAS :OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.Formule :C14H11N3ODegré de pureté :99.49% - 99.65%Couleur et forme :SolidMasse moléculaire :237.26Ref: TM-T2040
1mg34,00€2mg47,00€5mg66,00€1mL*10mM (DMSO)66,00€10mg92,00€25mg164,00€50mg299,00€100mg540,00€COH-SR4
CAS :COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formule :C13H8Cl4N2ODegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :350.03WZ4003
CAS :WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formule :C25H29ClN6O3Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :496.99Ref: TM-T6291
5mg48,00€1mL*10mM (DMSO)50,00€10mg73,00€25mg111,00€50mg166,00€100mg241,00€200mg358,00€500mg590,00€GSK-LSD1 dihydrochloride
CAS :GSK-LSD1 dihydrochloride: potent LSD1 inhibitor, >1000x selective over MAO-A/B, LSD2, IC50: 16 nM.Formule :C14H22Cl2N2Degré de pureté :98.72% - >99.99%Couleur et forme :SolidMasse moléculaire :289.24Ref: TM-T2315
1mg38,00€2mg50,00€5mg67,00€1mL*10mM (DMSO)67,00€10mg98,00€25mg198,00€50mg301,00€100mg495,00€500mg1.054,00€Fraxinellone
CAS :1.Formule :C14H16O3Degré de pureté :99.35% - 99.92%Couleur et forme :SolidMasse moléculaire :232.27Ref: TM-T6S0071
2mg34,00€5mg50,00€1mL*10mM (DMSO)81,00€10mg84,00€25mg152,00€50mg222,00€100mg334,00€200mg494,00€HIF-2α-IN-4
CAS :HIF-2a translation inhibitor is a compound used as a molecular building block.Formule :C9H9N3O4S2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :287.32Ref: TM-T50099
5mg37,00€1mL*10mM (DMSO)44,00€10mg60,00€25mg111,00€50mg200,00€100mg299,00€200mg430,00€I-BRD9
CAS :I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.Formule :C22H22F3N3O3S2Degré de pureté :98.16% - 99.51%Couleur et forme :SolidMasse moléculaire :497.55Ref: TM-T6859
1mg38,00€2mg49,00€5mg71,00€1mL*10mM (DMSO)79,00€10mg107,00€25mg205,00€50mg389,00€100mg577,00€ABBV-744
CAS :ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.Formule :C28H30FN3O4Degré de pureté :97.03% - >99.99%Couleur et forme :SolidMasse moléculaire :491.55Ref: TM-T4697
1mg44,00€2mg56,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg142,00€25mg284,00€50mg409,00€100mg500,00€200mg718,00€Piribedil
CAS :Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.Formule :C16H18N4O2Degré de pureté :99.79% - 99.82%Couleur et forme :SolidMasse moléculaire :298.34Deoxyshikonin
CAS :1.Formule :C16H16O4Degré de pureté :99.36% - ≥95%Couleur et forme :SolidMasse moléculaire :272.3MRTX-1719
CAS :MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.Formule :C23H18ClFN6O2Degré de pureté :98.27% - 99.18%Couleur et forme :SolidMasse moléculaire :464.88Pim1/AKK1-IN-1
CAS :Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.Formule :C20H13N5ODegré de pureté :97.03% - 98.69%Couleur et forme :SolidMasse moléculaire :339.35Ref: TM-T5093
1mg85,00€2mg124,00€5mg173,00€1mL*10mM (DMSO)192,00€10mg263,00€25mg464,00€50mg672,00€100mg945,00€dBET6
CAS :dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.Formule :C42H45ClN8O7SDegré de pureté :97.57% - 99.12%Couleur et forme :SolidMasse moléculaire :841.37Ref: TM-T5130
1mg50,00€5mg92,00€1mL*10mM (DMSO)148,00€10mg160,00€25mg290,00€50mg467,00€100mg675,00€200mg850,00€500mg1.243,00€SGC-SMARCA-BRDVIII
CAS :SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,Formule :C19H25N5O3Degré de pureté :99.54% - 99.92%Couleur et forme :SolidMasse moléculaire :371.43Ref: TM-T9568
1mg44,00€1mL*10mM (DMSO)54,00€5mg66,00€10mg101,00€25mg222,00€50mg356,00€100mg530,00€500mg1.153,00€5-AIQ
CAS :5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.Formule :C9H8N2ODegré de pureté :95.95%Couleur et forme :SolidMasse moléculaire :160.17BRD4770
CAS :BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.Formule :C25H23N3O3Degré de pureté :99.53% - 99.82%Couleur et forme :SolidMasse moléculaire :413.47Hispidulin
CAS :Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).Formule :C16H12O6Degré de pureté :98.53% - 99.87%Couleur et forme :SolidMasse moléculaire :300.26KC7F2
CAS :KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.Formule :C16H16Cl4N2O4S4Degré de pureté :98% - 99.11%Couleur et forme :SolidMasse moléculaire :570.38RK-287107
CAS :RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).Formule :C22H26F2N4O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :416.46MI-463
CAS :MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).Formule :C24H23F3N6SDegré de pureté :99.18% - >99.99%Couleur et forme :SolidMasse moléculaire :484.54Bempedoic acid
CAS :Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formule :C19H36O5Degré de pureté :99.85% - 99.94%Couleur et forme :SolidMasse moléculaire :344.49Ref: TM-T3625
2mg34,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg70,00€25mg118,00€50mg207,00€100mg333,00€500mg797,00€Ilorasertib
CAS :Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54PF-CBP1 hydrochloride
CAS :PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Formule :C29H37ClN4O3Degré de pureté :97.11% - 99.02%Couleur et forme :SolidMasse moléculaire :525.08Atractylenolide I
CAS :Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.Formule :C15H18O2Degré de pureté :97.55% - 99.92%Couleur et forme :SolidMasse moléculaire :230.30EED226
CAS :EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.Formule :C17H15N5O3SDegré de pureté :98.14% - 99.33%Couleur et forme :SolidMasse moléculaire :369.4Iniparib
CAS :Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).Formule :C7H5IN2O3Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :292.03Ref: TM-T6224
5mg52,00€1mL*10mM (DMSO)52,00€10mg73,00€25mg119,00€50mg216,00€100mg340,00€200mg540,00€500mg863,00€GLPG0634 analog
CAS :GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.Formule :C23H18N6O2Degré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :410.43Ref: TM-T3076
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg137,00€25mg250,00€50mg442,00€100mg623,00€500mg1.305,00€NVP-TNKS656
CAS :NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.Formule :C27H34N4O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :494.58Ref: TM-T3261
1mg43,00€2mg54,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg122,00€25mg248,00€50mg421,00€100mg617,00€RBN012759
CAS :RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.Formule :C19H23FN2O3SDegré de pureté :98.87% - 99.96%Couleur et forme :SolidMasse moléculaire :378.46Ref: TM-T22414
2mgÀ demander1mg104,00€5mg250,00€1mL*10mM (DMSO)274,00€10mg373,00€25mg645,00€50mg938,00€100mg1.311,00€200mg1.768,00€MLN8054
CAS :MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formule :C25H15ClF2N4O2Degré de pureté :98.07% - 98.26%Couleur et forme :SolidMasse moléculaire :476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€1mL*10mM (DMSO)88,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€1,2-Dipalmitoyl-sn-glycerol
CAS :1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.Formule :C35H68O5Degré de pureté :97.84% - 99.78%Couleur et forme :SolidMasse moléculaire :568.91Ruboxistaurin mesylate
CAS :Ruboxistaurin: PKC beta inhibitor, eases oxidative stress, heart issues & nephropathy in diabetic rats, halts retinal neovascularization.Formule :C29H32N4O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.65AZ505
CAS :AZ505 is an effective and specific SMYD2 inhibitor (IC50: 0.12 μM).Formule :C29H38Cl2N4O4Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :577.54Ref: TM-TQ0100
1mg60,00€5mg130,00€1mL*10mM (DMSO)165,00€10mg178,00€25mg295,00€50mg462,00€100mg623,00€MR837
CAS :MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.Formule :C16H14N2OSDegré de pureté :99.77% - 99.85%Couleur et forme :SolidMasse moléculaire :282.36Ref: TM-T8879
2mg38,00€5mg55,00€1mL*10mM (DMSO)66,00€10mg92,00€25mg138,00€50mg243,00€100mg355,00€200mg502,00€MK-8617
CAS :MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).Formule :C24H21N5O4Degré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :443.45Bromosporine
CAS :Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formule :C17H20N6O4SDegré de pureté :99.65% - 99.79%Couleur et forme :SolidMasse moléculaire :404.44Ref: TM-T6255
1mg44,00€2mg57,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg133,00€25mg260,00€50mg416,00€100mg665,00€200mg888,00€SP-146
SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).Formule :C25H20FN7ODegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :453.47Ref: TM-T8685
1mg84,00€5mg166,00€1mL*10mM (DMSO)168,00€10mg245,00€25mg404,00€50mg567,00€100mg767,00€200mg1.018,00€8-CHLOROQUINAZOLIN-4(1H)-ONE
CAS :8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)Formule :C8H5ClN2ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :180.59(R)-(-)-JQ1 Enantiomer
CAS :(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)
Formule :C23H25ClN4O2SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :456.99ICG001
CAS :ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.Formule :C33H32N4O4Degré de pureté :99.06% - 99.95%Couleur et forme :SolidMasse moléculaire :548.63Ref: TM-T2237
1mg34,00€5mg66,00€1mL*10mM (DMSO)81,00€10mg101,00€25mg197,00€50mg341,00€100mg530,00€500mg1.134,00€Rucaparib hydrochloride
CAS :Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.Formule :C19H19ClFN3OCouleur et forme :SolidMasse moléculaire :359.83GSK1379725A
CAS :GSK1379725A is a selective BPTF ligand (Kd = 2.8 μM).
Formule :C23H23FN6O3Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :450.47DMOG
CAS :DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.Formule :C6H9NO5Degré de pureté :80.23% - 99.98%Couleur et forme :SolidMasse moléculaire :175.14Bobcat339
CAS :Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.Formule :C16H12ClN3ODegré de pureté :97.79% - 98.76%Couleur et forme :SolidMasse moléculaire :297.74Rucaparib acetate
CAS :Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.Formule :C21H22FN3O3Couleur et forme :SolidMasse moléculaire :383.423JQEZ5
CAS :JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).Formule :C30H38N8O2Degré de pureté :98.14% - ≥98%Couleur et forme :SolidMasse moléculaire :542.68Protein kinase inhibitor 6
CAS :Protein kinase inhibitor 6 is a protein kinase inhibitor.Formule :C13H9FN2SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T9779
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg86,00€25mg163,00€50mg222,00€100mg324,00€200mg440,00€MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Formule :C103H156N28O24S2Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :2234.64EB-47 dihydrochloride
CAS :EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).Formule :C24H29Cl2N9O6Couleur et forme :SolidMasse moléculaire :610.45PIN1 inhibitor API-1
CAS :API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.Formule :C15H13F3N6O2Degré de pureté :98.48%Couleur et forme :SolidMasse moléculaire :366.3Ref: TM-T16538
1mg57,00€5mg120,00€1mL*10mM (DMSO)133,00€10mg222,00€25mg326,00€50mg485,00€100mg612,00€200mg850,00€500mg1.243,00€Amodiaquine
CAS :Amodiaquine is a synthetic aminoquinoline, used to treat malaria.Formule :C20H22ClN3ODegré de pureté :99.78% - 99.99%Couleur et forme :Crystals From Absolute Ethanol SolidMasse moléculaire :355.86Ref: TM-T8381
1mg49,00€2mg66,00€5mg90,00€1mL*10mM (DMSO)105,00€10mg170,00€25mg281,00€50mg394,00€100mg550,00€XMD8-92
CAS :XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).Formule :C26H30N6O3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :474.55Ruboxistaurin
CAS :Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.Formule :C28H28N4O3Couleur et forme :SolidMasse moléculaire :468.55YKL-06-061
CAS :YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formule :C30H37N7O2Degré de pureté :99.52% - 99.79%Couleur et forme :SolidMasse moléculaire :527.66MS31 trihydrochloride
MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.Formule :C20H30Cl3N3O2Couleur et forme :SolidMasse moléculaire :450.83SC-43
CAS :SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).Formule :C21H13ClF3N3O2Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :431.85-Ph-IAA
CAS :5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.Formule :C16H13NO2Degré de pureté :99.37% - 99.973%Couleur et forme :SolidMasse moléculaire :251.28Ethyl 3,4-dihydroxybenzoate
CAS :Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formule :C9H10O4Degré de pureté :99.88%Couleur et forme :White Crystal Or PowderMasse moléculaire :182.17Birabresib
CAS :Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4Formule :C25H22ClN5O2SDegré de pureté :98.3% - 99.36%Couleur et forme :SolidMasse moléculaire :491.99Ref: TM-T6032
2mg46,00€5mg70,00€1mL*10mM (DMSO)74,00€10mg90,00€25mg142,00€50mg222,00€100mg375,00€200mg560,00€500mg893,00€(+)-JQ-1
CAS :(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.Formule :C23H25ClN4O2SDegré de pureté :97.57% - 99.97%Couleur et forme :SolidMasse moléculaire :456.99Ref: TM-T2110
1mg34,00€2mg42,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg74,00€25mg90,00€50mg137,00€100mg178,00€200mg268,00€500mg485,00€AZD-2461
CAS :AZD2461 is a novel PARP inhibitor.Formule :C22H22FN3O3Degré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :395.43Menin-MLL inhibitor 20
CAS :Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.Formule :C33H40N8O4Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :612.72Ref: TM-T9399
1mg38,00€5mg86,00€1mL*10mM (DMSO)95,00€10mg128,00€25mg250,00€50mg369,00€100mg527,00€200mg712,00€Abrocitinib
CAS :Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Formule :C14H21N5O2SDegré de pureté :99.09% - 99.91%Couleur et forme :SolidMasse moléculaire :323.41Isoxazole
CAS :Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.Formule :C3H3NODegré de pureté :98% - 99.34%Couleur et forme :Colorless LiquidMasse moléculaire :69.06Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14UMB298
CAS :UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.Formule :C27H31ClN4O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :479.01Ref: TM-T9194
1mg46,00€5mg94,00€1mL*10mM (DMSO)99,00€10mg149,00€25mg250,00€50mg351,00€100mg480,00€200mg622,00€3-methyl-1,2,3,4-tetrahydroquinazolin-2-one
CAS :3-methyl-1,2,3,4-tetrahydroquinazolin-2-one is a inhibitor of BRD4 .Formule :C9H10N2ODegré de pureté :99.3% - 99.64%Couleur et forme :SolidMasse moléculaire :162.19Ref: TM-T50006
2mg37,00€5mg52,00€1mL*10mM (DMSO)56,00€10mg78,00€25mg119,00€50mg172,00€100mg259,00€500mg642,00€Alobresib
CAS :Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.Formule :C26H23N5O2Degré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :437.49Ref: TM-T8495
1mg70,00€2mg87,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg260,00€25mg507,00€50mg713,00€100mg982,00€PKC-iota inhibitor 1
CAS :PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formule :C21H22N6ODegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :374.44Ref: TM-T8764
1mg107,00€2mg152,00€5mg219,00€1mL*10mM (DMSO)226,00€10mg349,00€25mg583,00€50mg833,00€100mg1.134,00€500mg2.268,00€Tubacin
CAS :Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.Formule :C41H43N3O7SDegré de pureté :97.62% - 98.75%Couleur et forme :SolidMasse moléculaire :721.86MT-DADMe-ImmA
CAS :MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).Formule :C13H19N5OSDegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :293.39Ref: TM-TQ0008
1mg70,00€5mg135,00€1mL*10mM (DMSO)169,00€10mg225,00€25mg399,00€50mg560,00€100mg787,00€200mg1.035,00€Reversine
CAS :Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Formule :C21H27N7ODegré de pureté :98% - 99.45%Couleur et forme :SolidMasse moléculaire :393.49Ref: TM-T1825
1mg35,00€2mg50,00€5mg66,00€1mL*10mM (DMSO)66,00€10mg84,00€25mg156,00€50mg212,00€100mg371,00€J-147
CAS :J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.Formule :C18H17F3N2O2Degré de pureté :99.61% - >99.99%Couleur et forme :SolidMasse moléculaire :350.33

