Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2235 produits trouvés pour "Chromatine/Épigénétique"
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MS37452
CAS :<p>MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).</p>Formule :C22H26N2O5Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :398.45Pamiparib
CAS :<p>Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor. It has potent PARP trapping, and capability to penetrate the brain.</p>Formule :C16H15FN4ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :298.31EPZ005687
CAS :<p>EPZ005687 is a potent and selective inhibitor of EZH2.</p>Formule :C32H37N5O3Degré de pureté :97.06% - 99.64%Couleur et forme :SolidMasse moléculaire :539.67Fluzoparib
CAS :<p>Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.</p>Formule :C22H16F4N6O2Degré de pureté :98.53% - 99.63%Couleur et forme :SolidMasse moléculaire :472.4GSK199
CAS :<p>GSK199 is a selective PAD4 inhibitor(IC50 of 200 nM in the absence of calcium).</p>Formule :C24H29ClN6O2Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :468.98653-47 hydrochloride
CAS :<p>653-47 hydrochloride boosts CREB inhibition by 666-15 and weakly inhibits CREB itself (IC50: 26.3 μM).</p>Formule :C20H20Cl2N2O3Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :407.29AMI-1
CAS :<p>AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1).</p>Formule :C21H14N2Na2O9S2Degré de pureté :97.53% - 99.9%Couleur et forme :DrypowderMasse moléculaire :548.45Bobcat339
CAS :<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Formule :C16H12ClN3ODegré de pureté :97.79% - 99.24%Couleur et forme :SolidMasse moléculaire :297.74Nicotinamide riboside chloride
CAS :<p>NR, also SRT647, is a B3 vitamin form; precursor to NAD+.</p>Formule :C11H15ClN2O5Degré de pureté :98.92% - 99.86%Couleur et forme :SolidMasse moléculaire :290.7Nudifloramide
CAS :<p>Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).</p>Formule :C7H8N2O2Degré de pureté :99.7% - ≥95%Couleur et forme :SolidMasse moléculaire :152.15PF-9363
CAS :<p>PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.</p>Formule :C20H20N4O6SDegré de pureté :99.03% - 99.7%Couleur et forme :SolidMasse moléculaire :444.46Anacardic Acid
CAS :<p>Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases.</p>Formule :C22H36O3Degré de pureté :97.47% - 99.87%Couleur et forme :SolidMasse moléculaire :348.52Cerdulatinib
CAS :<p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>Formule :C20H27N7O3SDegré de pureté :98.74% - 99.49%Couleur et forme :SolidMasse moléculaire :445.54CPI-637
CAS :<p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>Formule :C22H22N6ODegré de pureté :99.89% - 99.95%Couleur et forme :SolidMasse moléculaire :386.45Upadacitinib
CAS :<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Formule :C17H19F3N6ODegré de pureté :98.96% - 99.94%Couleur et forme :SolidMasse moléculaire :380.371,5-Isoquinolinediol
CAS :<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formule :C9H7NO2Degré de pureté :98.29% - 99.35%Couleur et forme :Of White To White PowderMasse moléculaire :161.16666-15
CAS :<p>666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.</p>Formule :C33H31Cl2N3O5Degré de pureté :99.41% - 99.88%Couleur et forme :SolidMasse moléculaire :620.52Pyridone 6
CAS :<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Formule :C18H16FN3ODegré de pureté :97.1% - 98.74%Couleur et forme :SolidMasse moléculaire :309.34Phthalazinone pyrazole
CAS :<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Formule :C18H15N5ODegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :317.34WHI-P97
CAS :<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Formule :C16H13Br2N3O3Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :455.1GN44028
CAS :<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Formule :C18H15N3O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :305.33JQ-1 (carboxylic acid)
CAS :<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Formule :C19H17ClN4O2SDegré de pureté :99.14% - 99.9%Couleur et forme :SolidMasse moléculaire :400.88TCS7010
CAS :<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Formule :C31H31ClFN7O2Degré de pureté :98.49% - 99.62%Couleur et forme :SolidMasse moléculaire :588.07BD750
CAS :<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Formule :C14H13N3OSDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :271.34Remodelin hydrobromide
CAS :<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Formule :C15H15BrN4SDegré de pureté :97.22% - 99.84%Couleur et forme :SolidMasse moléculaire :363.2752,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS :<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Formule :C16H13Cl2N3O2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :350.2γ-Oryzanol
CAS :<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Formule :C40H58O4Degré de pureté :mixture - mixtureCouleur et forme :White Or White Crystalline Powder OdourlessMasse moléculaire :602.9AZ9482
CAS :<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Formule :C26H22N6O2Degré de pureté :99.18% - 99.86%Couleur et forme :SolidMasse moléculaire :450.49AT-9283 HCl
CAS :<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Formule :C19H24ClN7O2Couleur et forme :SolidMasse moléculaire :417.89Ro 31-8220 Mesylate
CAS :<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formule :C25H23N5O2S·CH4O3SDegré de pureté :98.79% - 99.02%Couleur et forme :SolidMasse moléculaire :553.65PF-06726304
CAS :<p>PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).</p>Formule :C22H21Cl2N3O3Degré de pureté :98.19% - 99.51%Couleur et forme :SolidMasse moléculaire :446.33BRD4 Inhibitor 30
CAS :<p>4-(2-fluorophenyl)-1,3-thiazol-2-one: has anti-inflammatory, antibacterial, antifungal, and antitumor properties.</p>Formule :C9H6FNOSDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :195.21WM-8014
CAS :<p>WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.</p>Formule :C20H17FN2O3SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :384.42PKC-iota inhibitor 1
CAS :<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Formule :C21H22N6ODegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :374.44Ilorasertib
CAS :<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Formule :C25H21FN6O2SDegré de pureté :96.17% - 97.49%Couleur et forme :SolidMasse moléculaire :488.54Chlorogenic Acid
CAS :<p>Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.</p>Formule :C16H18O9Degré de pureté :98.84% - 99.67%Couleur et forme :SolidMasse moléculaire :354.31GSK484 hydrochloride
CAS :<p>GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.</p>Formule :C27H32ClN5O3Degré de pureté :98.32% - 99.62%Couleur et forme :SolidMasse moléculaire :510.03JNJ-42041935
CAS :<p>JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.</p>Formule :C12H6ClF3N4O3Degré de pureté :99.58% - ≥95%Couleur et forme :SolidMasse moléculaire :346.65UPF 1069
CAS :<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Formule :C17H13NO3Degré de pureté :98.80% - 99.88%Couleur et forme :SolidMasse moléculaire :279.29HJ-PI01
CAS :<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Formule :C14H11NO2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :225.24GSK-J1
CAS :<p>GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.</p>Formule :C22H23N5O2Degré de pureté :99.23% - 99.67%Couleur et forme :SolidMasse moléculaire :389.45PJ34 hydrochloride
CAS :<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Formule :C17H18ClN3O2Degré de pureté :98.87% - ≥95%Couleur et forme :SolidMasse moléculaire :331.8NCGC00244536
CAS :<p>NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).</p>Formule :C25H22N2O2Degré de pureté :97.2% - 99.72%Couleur et forme :SolidMasse moléculaire :382.45SAR-20347
CAS :<p>SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).</p>Formule :C21H18ClFN4O4Degré de pureté :98.99% - 99.77%Couleur et forme :SolidMasse moléculaire :444.84Lomeguatrib
CAS :<p>Lomeguatrib (PaTrin-2), a modified guanine base, inhibits the activity of DNA repair protein O(6)-alkylguanine-DNA alkyltransferase (MGMT) .</p>Formule :C10H8BrN5OSDegré de pureté :99.26% - >99.99%Couleur et forme :SolidMasse moléculaire :326.17WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Formule :C16H14Br2ClN3O3Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :491.56Hesperadin
CAS :<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formule :C29H32N4O3SDegré de pureté :98.04% - 99.44%Couleur et forme :SolidMasse moléculaire :516.65Selisistat
CAS :<p>Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).</p>Formule :C13H13ClN2ODegré de pureté :98.53% - 99.94%Couleur et forme :SolidMasse moléculaire :248.71Methyl L-histidinate dihydrochloride
CAS :<p>The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat</p>Formule :C7H13Cl2N3O2Degré de pureté :99.74%Couleur et forme :White To Off-White PowderMasse moléculaire :242.1A-196
CAS :<p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>Formule :C18H16Cl2N4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :359.253-TYP
CAS :<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Formule :C7H6N4Degré de pureté :99.16% - >99.99%Couleur et forme :SolidMasse moléculaire :146.15Splitomicin
CAS :<p>Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a</p>Formule :C13H10O2Degré de pureté :97.09% - 99.11%Couleur et forme :SolidMasse moléculaire :198.224-Phenylbutyric acid
CAS :<p>4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.</p>Formule :C10H12O2Degré de pureté :98.40% - 99.76%Couleur et forme :SolidMasse moléculaire :164.2dencichine
CAS :<p>Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.</p>Formule :C5H8N2O5Degré de pureté :99.93% - ≥95%Couleur et forme :SolidMasse moléculaire :176.13CPI-455
CAS :<p>CPI-455 is a specific KDM5 inhibitor.</p>Formule :C16H14N4ODegré de pureté :97.87% - 99.03%Couleur et forme :SolidMasse moléculaire :278.31BAZ1A-IN-1
CAS :<p>BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.</p>Formule :C16H12N4O3SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :340.36I-CBP112
CAS :<p>I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.</p>Formule :C27H36N2O5Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :468.59MI-503
CAS :<p>MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.</p>Formule :C28H27F3N8SDegré de pureté :99.87% - 99.99%Couleur et forme :SolidMasse moléculaire :564.63AZD1208
CAS :<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formule :C21H21N3O2SDegré de pureté :97.24% - 99.83%Couleur et forme :SolidMasse moléculaire :379.48Niraparib hydrochloride
CAS :<p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>Formule :C19H21ClN4ODegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :356.85B2
CAS :<p>B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease</p>Formule :C20H17ClN4O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :396.83C-7280948
CAS :<p>C-7280948 is a PRMT1 inhibitor.</p>Formule :C14H16N2O2SDegré de pureté :99.55% - ≥95%Couleur et forme :SolidMasse moléculaire :276.35Birabresib
CAS :<p>Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4</p>Formule :C25H22ClN5O2SDegré de pureté :98.3% - 99.36%Couleur et forme :SolidMasse moléculaire :491.99Amodiaquine
CAS :<p>Amodiaquine is a synthetic aminoquinoline, used to treat malaria.</p>Formule :C20H22ClN3ODegré de pureté :99.78% - 99.99%Couleur et forme :Crystals From Absolute Ethanol SolidMasse moléculaire :355.86DMOG
CAS :<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formule :C6H9NO5Degré de pureté :80.23% - 99.98%Couleur et forme :SolidMasse moléculaire :175.14MR837
CAS :<p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>Formule :C16H14N2OSDegré de pureté :99.77% - 99.85%Couleur et forme :SolidMasse moléculaire :282.36MK-8617
CAS :<p>MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).</p>Formule :C24H21N5O4Degré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :443.45NVP-TNKS656
CAS :<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Formule :C27H34N4O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :494.58RBN012759
CAS :<p>RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.</p>Formule :C19H23FN2O3SDegré de pureté :98.87% - 99.96%Couleur et forme :SolidMasse moléculaire :378.461,2-Dipalmitoyl-sn-glycerol
CAS :<p>1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.</p>Formule :C35H68O5Degré de pureté :97.84% - 99.78%Couleur et forme :SolidMasse moléculaire :568.91Atractylenolide I
CAS :<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formule :C15H18O2Degré de pureté :97.55% - 99.92%Couleur et forme :SolidMasse moléculaire :230.3MI-463
CAS :<p>MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).</p>Formule :C24H23F3N6SDegré de pureté :99.18% - >99.99%Couleur et forme :SolidMasse moléculaire :484.54KC7F2
CAS :<p>KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.</p>Formule :C16H16Cl4N2O4S4Degré de pureté :98% - 99.11%Couleur et forme :SolidMasse moléculaire :570.38GLPG0634 analog
CAS :<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Formule :C23H18N6O2Degré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :410.43ABBV-744
CAS :<p>ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.</p>Formule :C28H30FN3O4Degré de pureté :97.03% - >99.99%Couleur et forme :SolidMasse moléculaire :491.55BRD4770
CAS :<p>BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.</p>Formule :C25H23N3O3Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :413.47CYC-116
CAS :<p>CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active</p>Formule :C18H20N6OSDegré de pureté :97.36% - 97.59%Couleur et forme :SolidMasse moléculaire :368.46ORY1001
CAS :<p>ORY1001: Oral LSD1/KDM1A inhibitor, highly selective, IC50 <20 nM.</p>Formule :C15H22N2·2HClDegré de pureté :99.85% - 99.96%Couleur et forme :SolidMasse moléculaire :303.27XL019
CAS :<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Formule :C25H28N6O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :444.53GSK1324726A
CAS :<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Formule :C25H23ClN2O3Degré de pureté :98.34% - 99.85%Couleur et forme :SolidMasse moléculaire :434.91Picolinamide
CAS :<p>Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.</p>Formule :C6H6N2ODegré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :122.12MS049
CAS :<p>MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively.</p>Formule :C15H24N2ODegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :248.36TCS-PIM-1-4a
CAS :<p>SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).</p>Formule :C11H6F3NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :273.23MS023
CAS :<p>MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8,</p>Formule :C17H25N3ODegré de pureté :98.31% - 99.87%Couleur et forme :SolidMasse moléculaire :287.4GSK121
CAS :<p>GSK121 is an inhibitor of selective PAD4.</p>Formule :C25H26F3N5O3Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :501.51PJ34
CAS :<p>PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.</p>Formule :C17H17N3O2Degré de pureté :95.05% - 99.85%Couleur et forme :SolidMasse moléculaire :295.34HIF-2α-IN-4
CAS :<p>HIF-2a translation inhibitor is a compound used as a molecular building block.</p>Formule :C9H9N3O4S2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :287.32SP-146
<p>SP-146 is a selective, potent and non-ATP-competitive Aurora B inhibitor(IC50 : 0.316 nM).</p>Formule :C25H20FN7ODegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :453.47Piribedil
CAS :<p>Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.</p>Formule :C16H18N4O2Degré de pureté :99.79% - 99.82%Couleur et forme :SolidMasse moléculaire :298.34dBET1
CAS :<p>dBET1 fuses (+)-JQ1 with thalidomide, degrades BET proteins via cereblon (EC50: 430 nM), and triggers apoptosis.</p>Formule :C38H37ClN8O7SDegré de pureté :98.02% - 99.3%Couleur et forme :SolidMasse moléculaire :785.27ZM39923 hydrochloride
CAS :<p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>Formule :C23H25NO·HClDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :367.91MK-8745
CAS :<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formule :C20H19ClFN5OSDegré de pureté :99.09% - 99.79%Couleur et forme :SolidMasse moléculaire :431.91JANEX-1
CAS :<p>JANEX-1: cell-permeable, reversible Jak3 inhibitor (IC50: 78 μM), ATP-competitive, selective; weak on JAK1/2, Zap/Syk, SRC.</p>Formule :C16H15N3O3Degré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :297.31SGC2085
CAS :<p>SGC2085 is an effective and selective coactivator-associated arginine methyltransferase 1 (CARM1) inhibitor (IC50: 50 nM).</p>Formule :C19H24N2O2Degré de pureté :99.61% - 99.71%Couleur et forme :SolidMasse moléculaire :312.41CPI-1205
CAS :<p>CPI-1205 是一种高效的选择性 EZH2 抑制剂（IC50：0.002 μM，EC50：0.032 μM）。</p>Formule :C27H33F3N4O3Degré de pureté :98.71% - 99.7%Couleur et forme :SolidMasse moléculaire :518.57DCLX069
CAS :<p>DCLX069: PRMT1 inhibitor, IC50=17.9µM, targets SAM pocket, inhibits breast/liver cancer, and AML cell growth.</p>Formule :C20H25N3O2Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :339.43AZD5305
CAS :<p>AZD5305 is a potent, selective and oral active PARP inhibitor.</p>Formule :C22H26N6O2Degré de pureté :98.68% - 99.93%Couleur et forme :SolidMasse moléculaire :406.48Peficitinib
CAS :<p>Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.</p>Formule :C18H22N4O2Degré de pureté :98.67% - 99.4%Couleur et forme :SolidMasse moléculaire :326.39E-7386
CAS :<p>E-7386 is an oral active CBP/ -catenin modulator.</p>Formule :C39H48FN9O4Degré de pureté :98.92% - 99.91%Couleur et forme :SolidMasse moléculaire :725.85Olaparib
CAS :<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>Formule :C24H23FN4O3Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :434.46TP-3654
CAS :<p>TP-3654 is a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).</p>Formule :C22H25F3N4ODegré de pureté :99.8% - 99.95%Couleur et forme :SolidMasse moléculaire :418.46E7449
CAS :<p>E7449 is a potent inhibitor of PARP1, PARP2, TNKS1, and TNKS2 with IC50s of 2, 1, ~50, and ~50 nM respectively.</p>Formule :C18H15N5ODegré de pureté :97.13%Couleur et forme :SolidMasse moléculaire :317.34Protosappanin A
CAS :<p>Protosappanin A combats brain inflammation, suppresses rat heart transplant rejection, fights MRSA, and inhibits HIV with a 12.6 uM IC50.</p>Formule :C15H12O5Degré de pureté :99.42% - 99.82%Couleur et forme :SolidMasse moléculaire :272.25Molibresib
CAS :<p>Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).</p>Formule :C22H22ClN5O2Degré de pureté :97.70% - 99.08%Couleur et forme :SolidMasse moléculaire :423.9(+)-JQ1 PA
CAS :<p>(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).</p>Formule :C22H20ClN5OSDegré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :437.95WM-1119
CAS :<p>WM-1119 is a highly potent, selective KAT6A/B inhibitor</p>Formule :C18H13F2N3O3SDegré de pureté :96.59% - 99.58%Couleur et forme :SolidMasse moléculaire :389.38XD14
CAS :<p>XD14 inhibits BET bromodomains with Kd: BRD4(1) 160nM, BRD2(1) 170nM, BRD3(1) 380nM, BRD3(2) 490nM, BRD2(2) 830nM, BRD4(2) 850nM.</p>Formule :C20H27N3O5SDegré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :421.51FL-411
CAS :<p>FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4.</p>Formule :C18H19N3O2SDegré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :341.43GSK3685032
CAS :<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Formule :C22H24N6OSDegré de pureté :98.56% - 99.49%Couleur et forme :SolidMasse moléculaire :420.53Daminozide
CAS :<p>Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily.</p>Formule :C6H12N2O3Degré de pureté :99.86%Couleur et forme :White Crystalline Solid Physical Description Odorless White Crystals Or Powder (Ntp 1992)Masse moléculaire :160.17GSK-5959
CAS :<p>GSK-5959 is a selective BRPF1 inhibitor with IC50 ~80 nM, 100-fold more specific than 35 other bromodomains.</p>Formule :C22H26N4O3Degré de pureté :98.35% - 98.65%Couleur et forme :SolidMasse moléculaire :394.47Deucravacitinib
CAS :<p>Deucravacitinib (BMS-986165) is a highly selective, orally bioavailable, allosteric TYK2 inhibitor.Cost-effective and quality-assured.</p>Formule :C20H19D3N8O3Degré de pureté :98.52% - >99.99%Couleur et forme :SolidMasse moléculaire :425.46Momelotinib
CAS :<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Formule :C23H22N6O2Degré de pureté :97.47% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46MS436
CAS :<p>MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.</p>Formule :C18H17N5O3SDegré de pureté :97.95% - 98.92%Couleur et forme :SolidMasse moléculaire :383.42SNS-314 Mesylate
CAS :<p>SNS-314 Mesylate (SNS-314) is an effective and specific Aurora A/B/C inhibitor. SNS-314 is less inhibition of Trk A/B, Fms, Flt4, c-Raf, Axl, and DDR2.</p>Formule :C18H15ClN6OS2·CH4O3SDegré de pureté :99.44% - 99.92%Couleur et forme :SolidMasse moléculaire :527.04BAY-598
CAS :<p>BAY 598 is a potent and selective competitive inhibitor of SMYD2, exhibiting >100-fold selectivity over SMYD3, SUV420H1, and SUV420H2. Cost-effective and quality-assured.</p>Formule :C22H20Cl2F2N6O3Degré de pureté :99.18% - 99.78%Couleur et forme :SolidMasse moléculaire :525.342',3',5'-triacetyl-5-Azacytidine
CAS :<p>2',3',5'-triacetyl-5-Azacytidine (Nsc291930) is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.</p>Formule :C14H18N4O8Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :370.31GSK046
CAS :<p>GSK046 (iBET-BD2), potent oral BET BD2 inhibitor; IC50: BRD2 (264 nM), BRD3 (98 nM), BRD4 (49 nM), BRDT (214 nM); immunomodulatory.</p>Formule :C23H27FN2O4Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :414.47RO495
CAS :<p>RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays</p>Formule :C17H14Cl2N6ODegré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :389.24GSK6853
CAS :<p>GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.</p>Formule :C22H27N5O3Degré de pureté :98.71% - 99.21%Couleur et forme :SolidMasse moléculaire :409.48(Z)-LFM-A13
CAS :<p>(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.</p>Formule :C11H8Br2N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :360Niraparib
CAS :<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39AKBA
CAS :<p>AKBA (3-O-Acetyl-11-keto-beta-boswellic acid), a natural component from frankincense, is a novel activator of Nrf2.</p>Formule :C32H48O5Degré de pureté :97.85% - 99.77%Couleur et forme :SolidMasse moléculaire :512.72MN-64
CAS :<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Formule :C18H16O2Degré de pureté :99.5% - 99.93%Couleur et forme :SolidMasse moléculaire :264.32SGC0946
CAS :<p>SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.</p>Formule :C28H40BrN7O4Degré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :618.57SMI-16a
CAS :<p>SMI-16a (PIM1/2 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (</p>Formule :C13H13NO3SDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :263.31OF-1
CAS :<p>OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.</p>Formule :C17H18BrN3O4SDegré de pureté :98.55% - ≥95%Couleur et forme :SolidMasse moléculaire :440.31AT9283
CAS :<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43SETDB1-TTD-IN-1
CAS :<p>SETDB1-TTD-IN-1 is a potent and selective inhibitor of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD, Kd = 88 nM).Cost-effective and quality-assured.</p>Formule :C28H31N5O2Degré de pureté :98.26% - 99.96%Couleur et forme :SolidMasse moléculaire :469.58JMJD7-IN-1
CAS :<p>JMJD7-IN-1 (Benzoic acid, 2,4-dichloro-, 5-nitro-8-quinolinyl ester) is a potent JMJD7 inhibitor, with an IC50 of 6.62 μM.</p>Formule :C16H8Cl2N2O4Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :363.15PF-9366
CAS :<p>PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM).</p>Formule :C20H19ClN4Degré de pureté :97.28% - 99.88%Couleur et forme :SolidMasse moléculaire :350.84AG-270
CAS :<p>AG-270 is an allosteric and orally active inhibitor of MAT2A.</p>Formule :C30H27N5O2Degré de pureté :98.28% - 98.87%Couleur et forme :SolidMasse moléculaire :489.57C-82
CAS :<p>C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.</p>Formule :C33H34N6O4Degré de pureté :98.86% - 99.66%Couleur et forme :SolidMasse moléculaire :578.66Itacitinib
CAS :<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Formule :C26H23F4N9ODegré de pureté :96.4% - 99.5%Couleur et forme :SolidMasse moléculaire :553.51A-966492
CAS :<p>A-96649 is a new-type and effective inhibitor. The Ki of A-966492 for PARP1 and PARP2 is 1 nM and 1.5 nM, respectively.</p>Formule :C18H17FN4ODegré de pureté :98.53% - 99.27%Couleur et forme :SolidMasse moléculaire :324.35GSK503
CAS :<p>GSK-503, a potent EZH2 inhibitor, has potential antitumor activity.</p>Formule :C31H38N6O2Degré de pureté :98% - 99.89%Couleur et forme :SolidMasse moléculaire :526.67PFI-4
CAS :<p>PFI-4 is a potent and selective and cell-permeable BRPF1 bromodomain inhibitor.</p>Formule :C21H24N4O3Degré de pureté :99.53% - ≥95%Couleur et forme :SolidMasse moléculaire :380.44NI-57
CAS :<p>NI-57 inhibits BRPF family proteins: BRPF1 (IC50=3.1nM), BRPF2 (IC50=46nM), BRPF3 (IC50=140nM).</p>Formule :C19H17N3O4SDegré de pureté :99.88% - >99.99%Couleur et forme :SolidMasse moléculaire :383.42Menin-MLL inhibitor MI-2
CAS :<p>Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.</p>Formule :C18H25N5S2Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :375.55Molibresib besylate
CAS :<p>Molibresib besylate (GSK 525762C) is a BET protein family inhibitor used in the study of refractory hematologic malignant diseases.</p>Formule :C28H28ClN5O5SDegré de pureté :99.64% - 99.64%Couleur et forme :SolidMasse moléculaire :582.07Oroxylin A
CAS :<p>Oroxylin A fights tumors, aids RAS therapy, promotes CaCo-2 cell apoptosis, blocks MCF-7 cell invasion and enhances leukemia treatment.</p>Formule :C16H12O5Degré de pureté :98.72% - 99.55%Couleur et forme :SolidMasse moléculaire :284.26Tofacitinib
CAS :<p>Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.</p>Formule :C16H20N6ODegré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :312.37GSK126
CAS :<p>GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).</p>Formule :C31H38N6O2Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :526.67Seclidemstat
CAS :<p>Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM.</p>Formule :C20H23ClN4O4SDegré de pureté :98.28% - 99.76%Couleur et forme :SolidMasse moléculaire :450.94Veliparib dihydrochloride
CAS :<p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>Formule :C13H18Cl2N4ODegré de pureté :98% - 99.81%Couleur et forme :SolidMasse moléculaire :317.21Remodelin
CAS :<p>Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.</p>Formule :C15H14N4SDegré de pureté :99.39% - 99.83%Couleur et forme :SolidMasse moléculaire :282.363PT-2385
CAS :<p>PT-2385 is a selective HIF-2α inhibitor (Kd<50 nM).</p>Formule :C17H12F3NO4SDegré de pureté :98.91% - 99.55%Couleur et forme :SolidMasse moléculaire :383.34Venadaparib
CAS :<p>Venadaparib, a PARP inhibitor (IC50: 1.4/1.0 nM for PARP1/2), is orally active, selective, not affecting PARP-5, used in tumor studies.</p>Formule :C23H23FN4O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :406.45RN-1 dihydrochloride
CAS :<p>RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).</p>Formule :C23H31Cl2N3O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :452.42Ruxolitinib
CAS :<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Formule :C17H18N6Degré de pureté :99.4% - >99.99%Couleur et forme :SolidMasse moléculaire :306.36GSK2801
CAS :<p>GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.</p>Formule :C20H21NO4SDegré de pureté :97.78% - 99.45%Couleur et forme :SolidMasse moléculaire :371.455-Methyl-2'-deoxycytidine
CAS :<p>5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.</p>Formule :C10H15N3O4Degré de pureté :99.18% - 99.69%Couleur et forme :SolidMasse moléculaire :241.242-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one
CAS :<p>2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP.</p>Formule :C10H11NOSDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :193.275-Fluoro-2'-deoxycytidine
CAS :<p>5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .</p>Formule :C9H12FN3O4Degré de pureté :97.91%Couleur et forme :Fine White PowderMasse moléculaire :245.21A-366
CAS :<p>A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.</p>Formule :C19H27N3O2Degré de pureté :97.28% - 99.8%Couleur et forme :SolidMasse moléculaire :329.44UNC3866 TFA(1872382-47-2 free base)
CAS :<p>UNC3866 TFA is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>Formule :C45H67F3N6O10Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :909.046-Thioguanine
CAS :<p>6-Thioguanine (2-Amino-6-purinethiol) is an antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.</p>Formule :C5H5N5SDegré de pureté :98.34% - >99.99%Couleur et forme :Odorless Or Almost Odorless Pale Yellow Crystalline PowderMasse moléculaire :167.19IOX4
CAS :<p>IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)</p>Formule :C15H16N6O3Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :328.33NEO2734
CAS :<p>NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains).</p>Formule :C22H24F3N3O3Degré de pureté :98.72% - 98.8%Couleur et forme :SolidMasse moléculaire :435.44GSK343
CAS :<p>GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and >1000 fold specificity activity against</p>Formule :C31H39N7O2Degré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :541.69Panaxadiol
CAS :<p>Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng.</p>Formule :C30H52O3Degré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :460.73XL228
CAS :<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formule :C22H31N9ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :437.54Tozasertib
CAS :<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Formule :C23H28N8OSDegré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :464.591-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS :<p>1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).</p>Formule :C17H19NODegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :253.34GSK620
CAS :<p>GSK620, a selective pan-BD2 inhibitor, has anti-inflammatory properties and favorable oral pharmacokinetics.</p>Formule :C18H19N3O3Degré de pureté :99.42% - 99.88%Couleur et forme :SolidMasse moléculaire :325.36Talazoparib
CAS :<p>Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).</p>Formule :C19H14F2N6ODegré de pureté :97.02% - 99.92%Couleur et forme :SolidMasse moléculaire :380.35Solcitinib
CAS :<p>Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.</p>Formule :C22H23N5O2Degré de pureté :99.61% - 99.82%Couleur et forme :SolidMasse moléculaire :389.45Dbet57
CAS :<p>dBET57: PROTAC-based BRD4BD1 degrader, DC50/5h at 500 nM, ineffective on BRD4BD2.</p>Formule :C34H31ClN8O5SDegré de pureté :99.36% - 99.52%Couleur et forme :SolidMasse moléculaire :699.18MAT2A inhibitor 4
CAS :<p>MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer</p>Formule :C16H15ClFNDegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :275.75Mivebresib
CAS :<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Formule :C22H19F2N3O4SDegré de pureté :98.74% - 99.32%Couleur et forme :SolidMasse moléculaire :459.47PHA-680632
CAS :<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Formule :C28H35N7O2Degré de pureté :98.2%Couleur et forme :SolidMasse moléculaire :501.623-Aminobenzamide
CAS :<p>3-Aminobenzamide (PARP-IN-1) is an effective inhibitor of PARP (IC50<50 nM in CHO cells) and a mediator of oxidant-induced myocyte dysfunction during</p>Formule :C7H8N2ODegré de pureté :98.4% - 99.5%Couleur et forme :White To Off-White PowderMasse moléculaire :136.15SF2523
CAS :<p>SF2523 is a highly selective and potent inhibitor.</p>Formule :C19H17NO5SDegré de pureté :99.1% - 99.51%Couleur et forme :SolidMasse moléculaire :371.41JNJ-64619178
CAS :<p>JNJ-64619178: selective, oral, pseudo-irreversible PRMT5 inhibitor (IC50: 0.14 nM), effective in lung cancer.</p>Formule :C22H23BrN6O2Degré de pureté :98.44% - 99.63%Couleur et forme :SolidMasse moléculaire :483.36GeA-69
CAS :<p>GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).</p>Formule :C20H16N2ODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :300.35TTK21
CAS :<p>TTK21 is an activator of CBP/p300 histone acetyltransferase activity.</p>Formule :C17H15ClF3NO2Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :357.75PX-478
CAS :<p>PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.</p>Formule :C13H20Cl4N2O3Degré de pureté :97% - 99.79%Couleur et forme :SolidMasse moléculaire :394.12LW6
CAS :<p>LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.</p>Formule :C26H29NO5Degré de pureté :98.1% - 98.22%Couleur et forme :SolidMasse moléculaire :435.51Dehydrocorydaline
CAS :<p>1.</p>Formule :C22H24NO4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :366.43Belzutifan
CAS :<p>"Belzutifan (MK-6482) is an oral HIF-2α inhibitor for ccRCC, with enhanced potency (IC50: 9 nM)."</p>Formule :C17H12F3NO4SDegré de pureté :99.34% - 99.88%Couleur et forme :SolidMasse moléculaire :383.34I-BET151
CAS :<p>I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).</p>Formule :C23H21N5O3Degré de pureté :97.34% - 99.63%Couleur et forme :SolidMasse moléculaire :415.44Veliparib
CAS :<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Formule :C13H16N4ODegré de pureté :98.66% - 99%Couleur et forme :SolidMasse moléculaire :244.29Tranylcypromine hemisulfate
CAS :<p>Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of</p>Formule :C9H11N1H2SO4Degré de pureté :98% - 99.96%Couleur et forme :SolidMasse moléculaire :182.23SGI-1027
CAS :<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.52GSK467
CAS :<p>GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).</p>Formule :C17H13N5O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :319.32MG 149
CAS :<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Formule :C22H28O3Degré de pureté :98.69% - 99.86%Couleur et forme :SolidMasse moléculaire :340.46UNC3866
CAS :<p>UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen.</p>Formule :C43H66N6O8Degré de pureté :88.06% - 99.62%Couleur et forme :SolidMasse moléculaire :795.02GW779439X
CAS :<p>GW779439X is an inhibitor of CDK.</p>Formule :C22H21F3N8Degré de pureté :97.87%Couleur et forme :SolidMasse moléculaire :454.45CCT241736
CAS :<p>CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3</p>Formule :C22H23Cl2N7Degré de pureté :96.2% - 99.81%Couleur et forme :SolidMasse moléculaire :456.37G244-LM
CAS :<p>G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.</p>Formule :C18H22N4O3S2Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :406.52AMG 900
CAS :<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formule :C28H21N7OSDegré de pureté :98.4% - 99.51%Couleur et forme :SolidMasse moléculaire :503.583-Methoxybenzamide
CAS :<p>3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.</p>Formule :C8H9NO2Degré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :151.16Amifostine trihydrate
CAS :<p>Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.</p>Formule :C5H15N2O3PS·3H2ODegré de pureté :99.71% - 99.80%Couleur et forme :SolidMasse moléculaire :268.27Fosifidancitinib
CAS :<p>Fosifidancitinib is a potent inhibitor of JAK 1 and JAK 3.</p>Formule :C21H21FN5O7PDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :505.39ARV-771
CAS :<p>ARV-771 is an effective BET degrader based on PROTAC technology.Cost-effective and quality-assured.</p>Formule :C49H60ClN9O7S2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :986.64Oclacitinib maleate
CAS :<p>Oclacitinib maleate is a selective JAK inhibitor (IC50: 10-99 nM; JAK1 cytokines: 36-249 nM), with no effect on 38 non-JAK kinases.</p>Formule :C15H23N5O2S·C4H4O4Degré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :453.51CPI-169 racemate
CAS :<p>CPI-169 racemate (CPI 169) is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.</p>Formule :C27H36N4O5SDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :528.66BET bromodomain inhibitor
CAS :<p>BET bromodomain inhibitor is a potent BET inhibitor.</p>Formule :C24H20ClN5O2Degré de pureté :98.22% - 99.85%Couleur et forme :SolidMasse moléculaire :445.9BIX-01294 trihydrochloride
CAS :<p>BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.</p>Formule :C28H38N6O2·3HClDegré de pureté :99.41% - 99.95%Couleur et forme :SolidMasse moléculaire :600.02ENMD-2076
CAS :<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47
