Endocrinologie/Hormones
Les inhibiteurs en endocrinologie/hormonaux sont des composés qui bloquent l'action des hormones ou interfèrent avec les voies de signalisation hormonales. Ces inhibiteurs sont essentiels pour étudier la régulation des systèmes endocriniens et pour développer des traitements pour les maladies liées aux hormones, telles que le diabète, les troubles de la thyroïde et les cancers hormonodépendants. En modulant l'activité hormonale, ces inhibiteurs peuvent aider à élucider les interactions complexes au sein du système endocrinien. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité en endocrinologie/hormonaux pour soutenir vos recherches en endocrinologie, pharmacologie et sciences médicales.
Sous-catégories appartenant à la catégorie "Endocrinologie/Hormones"
- Récepteur des androgènes(211 produits)
- Annexine A(11 produits)
- Aromatase(20 produits)
- Récepteur d'œstrogène/progestatif(50 produits)
- GPR(1 produits)
- Récepteur des glucocorticoïdes(154 produits)
- LHRH(1 produits)
- Récepteur opioïde(298 produits)
- Récepteur de prostaglandine(120 produits)
- RAAS(88 produits)
- Réductase(52 produits)
- Somatostatine(49 produits)
- Récepteur des hormones thyroïdiennes (THR)(26 produits)
- Récepteur de la vasopressine(45 produits)
Affichez 6 plus de sous-catégories
3193 produits trouvés pour "Endocrinologie/Hormones"
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L 363564
CAS :<p>L 363564 is a kidney renin inhibitor.</p>Formule :C54H76N12O10Couleur et forme :SolidMasse moléculaire :1053.276Aliskiren D6 Hydrochloride
CAS :<p>Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).</p>Formule :C30H54ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :594.26Angiotensin amide
CAS :<p>Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.</p>Formule :C49H70N14O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1031.17β-Lipotropin (60-65)
CAS :<p>β-Lipotropin (60-65) (β-LPH (60-65)), an opioid agonist, is a significant [1] opioid peptide.</p>Formule :C33H47N9O8SCouleur et forme :SolidMasse moléculaire :729.85T4-ATA (S-isomer)
<p>T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA.</p>Formule :C19H15I4NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :893.014'-hydroxy Tamoxifen
CAS :<p>It is a metabolite of tamoxifen and an estrogen receptor modulator.</p>Formule :C26H29NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.511α-Hydroxy-3-epi-vitamin D3
CAS :<p>1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1].</p>Formule :C27H44O2Couleur et forme :SolidMasse moléculaire :400.647Dynorphin B (1-13) (TFA)
<p>Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor .</p>Formule :C76H116N21F3O19Couleur et forme :SolidMasse moléculaire :1684.86PROTAC ERRα Degrader-3
CAS :PROTAC ERRα Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERRα protein.Formule :C47H50F6N6O7SCouleur et forme :SolidMasse moléculaire :957.0Herkinorin
CAS :<p>Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.</p>Formule :C28H30O8Couleur et forme :SolidMasse moléculaire :494.53Ac-RYYRIK-NH2
CAS :NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.Formule :C44H70N14O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :939.12ALR2-IN-6
<p>ALR2-IN-6 (compound 9) is a potent competitive inhibitor of ALR2, with a Ki value of 0.064 μM. It is applicable in research related to neuropathy, retinopathy, and nephropathy.</p>Formule :C21H19BrFN3OCouleur et forme :SolidMasse moléculaire :427.06955Ac-RYYRWK-NH2 TFA
CAS :<p>Ac-RYYRWK-NH2: potent, specific NOP receptor partial agonist with 0.071 nM affinity; no affinity for μ/κ/δ-opioid receptors.</p>Formule :C51H70F3N15O11Couleur et forme :SolidMasse moléculaire :1126.21Antitumor agent-195
<p>Antitumor agent-195 (compound 16c) is a dual-targeting agent that simultaneously targets STAT3 and NQO1. At a concentration of 1 μM, it significantly inhibits the phosphorylation of STAT3 at the Tyr705 site and effectively induces apoptosis in MDA-MB-231 and MDA-MB-468 breast cancer cells. As a substrate of NQO1, Antitumor agent-195 markedly increases ROS production, causing severe DNA damage in a dose-dependent manner. It also demonstrates strong antitumor properties in MDA-MB-231 xenograft models.</p>Formule :C22H22N2O4Couleur et forme :SolidMasse moléculaire :378.42THR-β agonist 2 diacetate
<p>THR-β agonist 2 diacetate (Compound 3) is a potent THR-β agonist with potential applications in researching metabolic disorders such as obesity, hyperlipidemia, hypercholesterolemia, and diabetes, as well as other conditions like steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis, and other related diseases and conditions.</p>Couleur et forme :Odour SolidOrphine
CAS :<p>Orphine is an opioid compound that can amplify the antinociceptive effects reduced by naloxone in mice.</p>Formule :C20H23N3OCouleur et forme :SolidMasse moléculaire :321.42[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Formule :C48H77N13O12Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :1028.2HINT1-IN-1
<p>HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).</p>Formule :C23H24N8O5Couleur et forme :SolidMasse moléculaire :492.49Melanin Concentrating Hormone, salmon TFA
<p>MCH (salmon) TFA is a 19-amino-acid neuropeptide affecting appetite, energy, sleep, and heart health via GPCR SLC-1/GPR24 and MCHR2.</p>Formule :C91H140F3N27O26S4Couleur et forme :SolidMasse moléculaire :2213.5BigLEN(mouse)
CAS :<p>GPR171 agonist from ProSAAS controls mouse appetite, reduces glutamate in paraventricular neurons via G protein.</p>Formule :C78H130N24O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1756.03(rel)-PROTAC ERRα Degrader-1
(rel)-PROTAC ERRα Degrader-1 is a relative configuration of PROTAC ERRα Degrader-1, which is an estrogen-related receptor alpha (ERRa) degrader.Formule :C54H49Cl2F6N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1108.91PROTAC ERRα Degrader-2
CAS :<p>PROTAC ERRα Degrader-2 is a compound consisting of an MDM2 ligand binding group, a linker, and an estrogen-related receptor alpha (ERRα) binding group.</p>Formule :C57H55Cl2F6N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1150.99PROTAC ER Degrader-4
CAS :<p>PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).</p>Formule :C53H67F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1005.2Floramanoside C
CAS :<p>Floramanoside C exhibits 2,2-diphenyl-1-picrylhydrazyl scavenging and aldose reductase inhibitory activities [1].</p>Formule :C21H18O15Couleur et forme :SolidMasse moléculaire :510.36KOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Formule :C21H25N3Couleur et forme :SolidMasse moléculaire :319.44Alunacedase alfa
CAS :<p>Alunacedase alfa (APN-01) is an angiotensin-converting enzyme 2 with antiviral activity.</p>Degré de pureté :99.1% (SDS-PAGE); 99.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 99.9% (SEC-HPLC)Couleur et forme :LiquidDAMGO (TFA)
CAS :DAMGO is a selective peptide agonist of the µ-opioid receptor .Formule :C28H36F3N5O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :627.61OT-R antagonist 2
CAS :OT-R antagonist 2 is a nonpeptide low molecular weight antagonist of OT-R .Formule :C28H29N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :471.55BI 653048
CAS :<p>BI 653048 is a selective and orally active agonist of nonsteroidal glucocorticoid (IC50: 55 nM). BI 653048 is also an HCV NS3 protease inhibitor.</p>Formule :C23H25F4N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.523-epi-25-hydroxy Vitamin D3
CAS :<p>3-epi-25-hydroxy Vitamin D3 lowers serum PTH in male weanling rats at 0.5 and 1 IU/g doses; doesn't affect females.</p>Formule :C27H44O2Couleur et forme :SolidMasse moléculaire :400.64Perindoprilat
CAS :<p>Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor.</p>Formule :C17H28N2O5Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :340.41PROTAC AR Degrader-4 TFA
PROTAC AR Degrader-4: IAP ligand, linker, AR binder; it's a SNIPER that degrades AR non-genetically.Formule :C45H68F3N3O11Couleur et forme :SolidMasse moléculaire :884.03Dynorphin A (1-8)
CAS :<p>Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.</p>Formule :C46H72N14O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :981.15Ac-RYYRWK-NH2
CAS :<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Formule :C49H69N15O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1012.17Cgp 38560
CAS :<p>CGP 38560 is a potent renin inhibitor.</p>Formule :C40H67N5O9S2Couleur et forme :SolidMasse moléculaire :826.12Nurr1 agonist 2
CAS :<p>Nurr1 agonist 2 with EC50 of 0.07 μM, boosts TH & VMAT2 mRNA, binds Nurr1 LBD at Kd 0.14 μM, for parkinsonism study.</p>Formule :C18H14O3SDegré de pureté :98.78%Couleur et forme :SoildMasse moléculaire :310.37Methylprednisolone Acetate
<p>Methylprednisolone Acetate(Depo-Medrate) has the ability to inhibit oxygen free radicals and can be used to treat acute spinal cord injuries.</p>Formule :C24H32O6Degré de pureté :99.74%Couleur et forme :Off-White SolidMasse moléculaire :416.51Dynorphin B (1-13)
CAS :Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.Formule :C74H115N21O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1570.849,10-Dihydrophenanthrene
CAS :<p>9,10-Dihydrophenanthrene has inhibitory activity against the androgen receptor and can be used in related research in the field of life sciences.</p>Formule :C14H12Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :180.25Brain Natriuretic Peptide (1-32), rat
CAS :<p>Rat Brain Natriuretic Peptide (1-32) is a 32-amino-acid peptide from heart, released when ventricles stretch excessively.</p>Formule :C146H239N47O44S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3452.94Azilsartan Medoxomil Potassium
CAS :<p>Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.</p>Formule :C30H23N4O8·KDegré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :606.62Zavacorilant
CAS :<p>Zavacorilant is capable of modulating glucocorticoid receptor (GR).</p>Formule :C25H26FN7O3S2Couleur et forme :SolidMasse moléculaire :555.65AZ 1729
CAS :<p>FFA2 modulator; inhibits cAMP, enhances 35SGTPγS binding (pEC50: 6.9, 7.23); alters Gi/Gq signaling; affects lipolysis, neutrophil migration.</p>Formule :C18H16FN5OSCouleur et forme :SolidMasse moléculaire :369.42Raloxifene 6-glucuronide
CAS :<p>Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8.</p>Formule :C34H35NO10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :649.71CP-472555
CAS :<p>CP-472555 is a selective nonsteroidal glucocorticoid receptor antagonist with anti-GR and anti-obesity activity in animal models.</p>Formule :C31H32N2O2Couleur et forme :SolidMasse moléculaire :464.60NH-3
CAS :<p>NH-3, an orally active THR antagonist with a 55 nM IC50, blocks thyroid hormone binding and cofactor recruitment.</p>Formule :C28H27NO6Degré de pureté :97.79% - 99.40%Couleur et forme :SolidMasse moléculaire :473.523-Cl-Pyridine-amide-acrylaldehyde-piperazine
<p>3-Cl-Pyridine-amide-acrylaldehyde-piperazine serves as a synthetic intermediate for LO-4-25. LO-4-25 is a ligand for the androgen receptor (AR) DNA binding domain and is linked to a truncated fumaramide handle via a connector. In 22Rv1 cells, LO-4-25 demonstrates potent degradation of both AR and AR-V7.</p>Couleur et forme :Odour SolidAntihypertensive agent 2
<p>Antihypertensive agent 2 (Compound 4g) exhibits effective antagonistic activities against angiotensin II receptor 1 and reduces blood pressure with equal or</p>Formule :C22H15NO3Couleur et forme :SolidMasse moléculaire :341.36BigLEN(rat)
CAS :<p>Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.</p>Formule :C76H128N24O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1746R4K1
<p>R4K1 is a cell-permeable stapled peptide that binds with high affinity to estrogen receptor (ER) α, inhibiting its interaction with coactivators. It penetrates breast cancer cells, regulating gene transcription and suppressing cell proliferation. R4K1 is applicable for tumor research.</p>Formule :C82H146N34O19Couleur et forme :SolidMasse moléculaire :1912.25
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